Gene RTKF1 (M.brevicollis)

RTKF1

Species: M.brevicollis
Alias: RTKF1
External Links:
Annotation:

Classification

Group: TK
Family: RTKF

Sequence

Name Sequence Type Origin Length Description Download
RTKF1.AA Protein None 923 None Fasta, JSON
RTKF1.kin_dom Protein Kinase Domain None 265 None Fasta, JSON

Protein domain

Protein domains of RTKF1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LDLa RTKF1.AA LDLa 371-410 31 6.2e-11 43.56 SMART 1-47 (47) Show / Hide 
Range on Protein: 371-410
Range on HMM: 1-47/47
Sequence Identity: 31% (15 aa)

HCPHV--PPFACLHSSHQILATQLCDGVADCPDGEDE------QHCSA
.||      |.|  ... |  ...|||. ||.||.||      ..|. 
TCPPDHPNQFQCG-NGRCIPKSWVCDGDNDCGDGSDEWPFFDPENCPQ
Ldl_recept_a RTKF1.AA Ldl_recept_a 391-408 50 2e-06 22.49 Pfam 22-41 (41) Show / Hide 
Range on Protein: 391-408
Range on HMM: 22-41/41
Sequence Identity: 50% (10 aa)

QLCDGVADCPDGEDE--QHC
..||| .|| ||.||  ..|
WVCDGDPDCHDGSDEWPENC
Kinase RTKF1.AA RTKF 650-913 63 9.5e-229 744.45 In-house 1-272 (272) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-272/272
Sequence Identity: 63% (172 aa)

LMIEEQLGHGNFGTIHRGYWIAQ-GQRQVVAIKHVHTQGLENGKRAILRECQLLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPHGDMKRYLSLHGS
.|..||||||.||..|.|||..| ||||.|||||.|||...|..|..||||...|.||.|.||...|||.|.|.|..|..|||||||||||.|||..|..
IMLGEQLGHGHFGRVHHGYWRQQKGQRQPVAIKHIHTQDMMNWRRQMLRECCAMNRVGQHPHIIQFFGILMTPFEQNEMAFVMEFAPHGDMRRYLQQHDV

DLELDQLLDAGRQ-VAEALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQHQDYYRSMSNEELAFRWMAPEAITHRKFTQQSDVWSFGM
||.....|||..| ||||..|||.||.|||||||||||||..||...||.|||||||||||||||||||.||||.|||||||||.||.|||.||||||||
DLGRAHMLDAAHQVVAEAMVFISRQGLVHRDVAARNVLVFEDQPRMYVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWSFGM

MLYEFVTRGDVPFGKMEHGGILLAIRRGLTPELPRDVP------ADIVRLCQATWTKTPEERPTFDILADML
||.|..||||||.|.|.|...|..||||.|...|...|      ..|..|||..||..||.||.|||..|.|
MLFELFTRGDVPYGNMPHPVVLQFIRRGKTLQMPDSCPPDVCRFVSIHWLCQRIWTFDPEQRPDFDIIEDHL
Kinase RTKF1.AA TK 650-913 19 3.4e-89 299.12 In-house 1-486 (486) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-486/486
Sequence Identity: 19% (96 aa)

LMIEEQLGHGNFG---TIHRGYWIAQ-----------------------GQRQVVAIKHVHTQGLENGKRAIL-----------------RECQLLNVVG
. ....||.|.||   ....| |. .                       |... ||.| ..    .. .. ..                  ...... .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHEHIVRIFGIVMSP---------LERDELSFVMEFAPHGD----MKRYLSLHGSD--------------------------------------------
.|..|||..|... .         ...  .  |||..||||     . ||  .  .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LELDQLLDAGRQVAEALAFISSQ------GFVHRDVAARNVLVFTEQP--------SLQVKITDFG---
                               | . |||   .|.|.......|.      .|||||.||||.||. . .         ...||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARVLSQH-----------------------QDYYRSMSNEELAFRWMAPEAIT---------HRKFTQQSDVWSFGMMLYEFVTRGDVPFGK-M
     ||| . ..                       |||||. |.  | .||||||...         ..||| .||||||| ...| .|.|..|..  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

EH---------GGILLAIRRG--------------LTPELPRDVP--------------ADIVRLCQATWTKTPEERPTFDILADML
 .           ..  .|||              . .. | . |              ... .|.|  | . ||.||||. | ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKF1.AA TyrKc 650-913 30 7.1e-85 289.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-280/280
Sequence Identity: 30% (90 aa)

LMIEEQLGHGNFGTIHRGYWIAQGQRQVVAIKHVHTQGLENGKRAILRECQLLNVVG-DHEHIVRIFGIVMSPLER----DELSFVMEFAPHGDMKRYLS
.  ...||.|.||....| |.     . ||.| ..       .....|| ...  .| .|..|||..|..... ..    . |  |||..|||| | || 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

LHGSDLELDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQH------QDYYRSMS--NEE--LAFRWMAPEAITHR
 |. .| ...||.   |.|.  ....|....||| ||||.||  ..   .|||.||||.| .  .      .||||...  ..   |  ||||||.| ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KFTQQSDVWSFGMMLYEFVTRGDVPFGK-----MEHGGILLAIRRGLTPELPRD--------VPADIVRLCQATWTKTPEERPTFDILADML
||| .||||||| ...|  |.|. |        |.   ..  ...|  .. | .         |... .. .  |   ||.||||  . . .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKF1.AA Pkinase_Tyr 650-913 33 3.4e-82 279.01 Pfam 1-270 (270) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-270/270
Sequence Identity: 33% (93 aa)

LMIEEQLGHGNFGTIHRGYWI--AQGQRQVVAIKHVHTQGLENG---KRAILRECQLLNVVGDHEHIVRIFGIVMSPLERDE--LSFVMEFAPHGDMKRY
. . ..||.|.||....|.|    ..... ||.| .  .|       ... .|| ...   |.|..|||  |...   ...   .  |||..||||.. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT--DQGEPNQIYIVMEYMPHGDLLDY

LSLH---GSDLELDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQHQDYY-RSMSNEELAFRWMAPEAITHRKFTQ
|  |   .  | . .||.  .|.|..... .|....|||.||||.||     ...|||.|||||| . .. ||| |. ..  |  .|||||.| ..||| 
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTT

QSDVWSFGMMLYEFVTRGDVP-FGKMEHGGILLAI-RRGLTPELPRDVPADIVRLCQATWTKTPEERPTFDILADML
.|||||||  ..| .|.|. | .  |    .. .| ..|   . |.. |..| .| .  | . ||.||||  .  .|
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKF1.AA UTK 650-913 27 4.9e-71 242.26 In-house 1-296 (296) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-296/296
Sequence Identity: 27% (82 aa)

LMIEEQLGHGNFGTIHRGYW--IA-QGQRQVVAIKHVHTQGLENGKRA----ILRECQ---LLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPHGDM
... .|||.|.||..|.. .  .. ... ..||.|   . .  . ...    ...|..   ..  .  |....|  |....      .  |.|... ||.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP---WMIVTEYMENGDL

KRYLSLHGSDLE-------LDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVFTEQ----PSLQVKITDFG---LARVLS--------QHQDYYRSMS
  ||  |. ...       |.|.|.  ...|.......|.||||||.||||.||.         ...|| |||   ..| ..        . ..||.. .
RSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH

NEELAFRWMAPEAITHR-KFTQQSDVWSFGMMLYEFVTRGDVPFGKMEHGGILLAIRRG--LTPELPRDVPADIVRLCQATWTKTPEERPTFDILADML
......|||||||.||. .||..|||||||  ..| .|.| .|.. | .  .......|  . .. |.|.|... || .. |...|.|||.|. | . .
QDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKF1.AA RTKA 650-895 27 1.8e-68 233.78 In-house 1-314 (314) Show / Hide 
Range on Protein: 650-895
Range on HMM: 1-314/314
Sequence Identity: 27% (86 aa)

LMIEEQLGHGNFGTIHRG-YWIAQ----GQRQVVAIKHVHTQGLENGKRAI---LRECQLLNVVGDHEHIVRIFGIVMSPLE---RDELSFVMEFAPHGD
. ... .|||.|.. ..  .  .        | ||||  .   | |.| ..   .||  ||  ..|..||.. .|..... .   .  .. |.|..||| 
MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQCVAIKECDDLML-NDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGN

MKRYLSLHG----------------------SDLELDQLLDAGRQVA-------EALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQH
 .  .  |                         |  .|.  | .|..       .|.|. .. | ||||||||||||.. || . .|  |||| ||... 
LRDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKCGIVHRDVAARNVLVMSLQPAFHCKLADFGLSRVMPS-

QDYYRSMSNEELAFRWMAPEAITHRKFTQQSDVWSFGMMLYEFVTRGDVPFG------------------------------KMEHGGILLAIRRGLTPE
 |||.| . .|. |||||||.|  |.. ..|||||||... | .|.| .|..                               .. . |  .  .| | .
SDYYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLP

LPRDVPADIVRLCQAT
.|. .|.   | | . 
MPPCCPPCLQRFCFWC
Kinase RTKF1.AA Src 650-913 34 2.5e-61 207.11 In-house 1-255 (255) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-255/255
Sequence Identity: 34% (93 aa)

LMIEEQLGHGNFGTIHRGYWIAQGQRQVVAIKHVHTQGLENGKRAILRECQLLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPHGDMKRYLS--LHG
.  ...|| |.||    |||  . .   ||.|      ...   | |.| |..  . .||..|... ..    . .    | |.  ||    ||     |
IKLCRKLGQGQFGEVWMGYWNGNTK---VAVKTLKPGTMSP--EAFLQEAQIMKKL-RHEKLVQLYAVCS---QEEPIYIVTEYMSHGSLLDYLKKDGEG

SDLELDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQHQDYYRSMSNEELAFRWMAPEAITHRKFTQQSDVWSFGM
. |.| ||.| . ||||  |...|. ..||| ||||||| ..     .|. ||||||.. .  | | . .   .  .|.|||||....||. ||||||| 
RHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN---VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGI

MLYEFVTRGDVPFGKMEHGGILLAIRRGLTPELPRDVPADIVR-LCQATWTKTPEERPTFDILADML
 |.| ||.| ||   |.    | .. ||     |. .|. .   . .  | |.||.||||..| . |
LLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase RTKF1.AA TK-Unique 650-913 27 5.5e-61 208.92 In-house 1-294 (294) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-294/294
Sequence Identity: 27% (83 aa)

LMIEEQLGHGNFGTIHRG-YWIAQ---GQRQVVAIKHVHTQGLENGKRAILRECQLLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPHGDMKRYLSL
| .....| |.||...|| .|      .....||.| ..    .  |.. |.| |... .|||..||...|. ...   .    .||..| |.   ||  
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD--EPWMIIMEYCPCGNLQHYLRT

HGSD-------------------------LELDQLLDAGRQVAEALAFISS--QGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQHQDYYRSMSN
 . .                         . . .|.  . |.| ......|  ...||||..|||||.      ...||.|||.|| .. ...| .. | 
CRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE---DKVCKICDFGMARDVYTNGVYSMMCSQ

EELAFRWMAPEAIT--HRKF-TQQSDVWSFGMMLYEFVTRGDVPFGKMEHGGILLAIRRGLTPELPRDV-PADIVRLCQATWTKTPEERPTFDILADML
...  ||||||..   |. . | .|||||||  ..| .| |  |...|    |. .||.| ....|  . . ..  | . .|.. |||||.|. ....|
GRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKF1.AA Ack 650-913 34 3.8e-58 194.74 In-house 1-266 (266) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-266/266
Sequence Identity: 34% (93 aa)

LMIEEQLGHGNFGTIHRGYWIA-QGQRQVVAIKHVHTQGLENG--KRAILRECQLLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPHGDMKRYLSLH
.   |.|| | ||  .|| | .  |..  ||.| .    .  .      ||| . .    ||.|.|| .|.|   |  . |  |.|.|| |     |  |
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSL-DHPHLVRLYGVV---LDQPMLMMVTELAPCGSLLDCLRKH

GS--DLELDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQHQDYYRSMSNE--ELAFRWMAPEAITHRKFTQQSDV
 .   . .  |.|  .|.|.....  .....|||.||||.|.|.      ||| |||| | | |  ||||.  .    . | |.|||...||.|.  |||
CRTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDD--RKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDV

WSFGMMLYEFVTRGDVPFGKMEHGGILLAIR-RGLTPELPRDVPADIVRLCQATWTKTPEERPTFDILADML
|.||  | |  . |  |.  .    || .|   |   . | . | ||  .   .|...|..||||  . | |
WMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase RTKF1.AA TKL 656-913 20 2.6e-51 176.76 In-house 1-364 (364) Show / Hide 
Range on Protein: 656-913
Range on HMM: 1-364/364
Sequence Identity: 20% (75 aa)

LGHGNFGTIHRGYWIAQG------QRQVVAIKHVHTQG-LENGK-----------------------RAILRECQLLNVVG-DHEHIVRIFG--------
.| | ||....|.|  .|        ..||.|  ...   |. |                           .| ...     .|..||.. |        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-IVMSP-LERDELSFVMEFAPHGD-MKRYLSLHGSDLELDQLLDAGRQVAEALAFISSQG--------FVHRDVAARNVLVF-----------TEQPSLQ
 ..|.|  .  .| .|||..|.|.   ...        ..|...  ...| ....  |..         .|||   .|.||.            ..    
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VKITDFGLARVLSQHQD---------------YYRSMSNEEL-AFRWMAPEAIT----------------HRKFTQQSDVWSFGMMLYEFVTRGDVPFGK
.||.||||.|..||...                .|.... .   .||||||..                 ........||.|||..|.| .||   |. .
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYD

MEH----------GGILLAIRRGLTPELP------------RDVPADIVRLCQATWTKTPEERPTFDILADML
. .            . ... .|| |..|             |.| .. .|.|  |   ||.||.|. . . |
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase RTKF1.AA Frk 650-917 31 1.8e-49 169.48 In-house 1-260 (260) Show / Hide 
Range on Protein: 650-917
Range on HMM: 1-260/260
Sequence Identity: 31% (85 aa)

LMIEEQLGHGNFGTIHRGYWIAQGQRQVVAIKHVHTQGLENGKRAILRECQLLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPHGDMKRYLS---LH
. .  .|| | || .  | |  .     ||.|.. .  ..   .  ||| |..  .  |  ..... .       . .  . |   || .. ||     .
IQLIRRLGSGQFGEVWEGLWNNT---TPVAVKTLKPGTMDP--NDFLREAQIMKKL-RHPKLIQLYAVCT---VEEPIYIITELMRHGSLQEYLQAINDK

GSDLELDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQHQD-YYRSMSNEELAFRWMAPEAITHRKFTQQSDVWSF
|. ... ||.|   |||  .|.. || ..|||.|||||||     .. .|| |||||||| . .   | |  .  .  .| ||||.   ||| .||||||
GRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLV---GEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSF

GMMLYEFVTRGDVPFGKMEHGGILLAIRRGLTPELPRDVPADIVRLCQATWTKTPEERPTFDILADMLAQHA
|..|.| .| | .|.  |    .|  . .|     | . |  .  . .  | . |..||||. |   | .. 
GILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase RTKF1.AA EGFR 650-914 32 1.8e-49 162.35 In-house 1-258 (258) Show / Hide 
Range on Protein: 650-914
Range on HMM: 1-258/258
Sequence Identity: 32% (86 aa)

LMIEEQLGHGNFGTIHRGYWIAQGQ--RQVVAIKHVHTQGLENGKRAILRECQLLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPHGDMKRYLSLHG
|     || | |||...| || .|.  .  |||| .. |  .. . ..|.|   .  | ||.|.||. |. |.    ...  |  . |.| .  |.  | 
LKKVKVLGSGAFGTVYKGIWIPEGENVKIPVAIKVLREQTGPKANEEMLDEAYVMASV-DHPHLVRLLGVCMH----SQMQLVTQYMPYGCLLDYVRQHK

SDLELDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQHQDYYRSMSNEELAFRWMAPEAITHRKFTQQSDVWSFGM
  .   .||  . |.|  . .   .  |||| ||||||| . .   .|||||||||..|.. .. |. ..   .. .||| | | ||..| ||||||.| 
DNIGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPN---HVKITDFGLAKLLEHDEKEYH-AQGGKMPIKWMALECIHHRCYTHQSDVWSYGV

MLYEFVTRGDVPFGKMEHGGILLAIRRGLTPELPRDVPADIVRLCQATWTKTPEERPTFDILADMLA
 . | .| |  |.  ..   |   . .|   . |     |.  .    |   .. |||| .|.  . 
TCWELMTFGQKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase RTKF1.AA S_TKc 650-913 23 4.1e-46 160.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 650-913
Range on HMM: 1-231/231
Sequence Identity: 23% (66 aa)

LMIEEQLGHGNFGTIHRGYWIAQGQRQVVAIKHVHTQGLENGKRAILRECQLLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPH--GDMKRYLSLHG
  | ...|.| ||. ......     ..|||| ..        . |.|| |.|    .|..||.....  .    |.| .|||....  ||...|.  .|
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRG

SD-----LELDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVFTEQPSLQVKITDFGLARVLSQHQDYYRSMSNEELAFRWMAPEAITHRKFTQ-QSD
.      .   .     .|...||... |.|..|||.   |.|. .     ..||.||||||.|          .       .|||| .   ...   .|
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCD

VWSFGMMLYEFVTRGDVPFGKMEHGGILLAIRRGLTPELPRDVPADIVRLCQATWTKTPEERPTFDILA--------DML
.||.| .|||... |  ||       . . ... .        . .   . .  ..| ||.||| ..|.          .
WWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase RTKF1.AA Pkinase 650-912 23 3.9e-45 160.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 650-912
Range on HMM: 1-293/293
Sequence Identity: 23% (73 aa)

LMIEEQLGHGNFGTIHRGYWIAQGQRQVVAIKHVHTQGLENGKRAILR---ECQLLNVVGDHEHIVRIFGIVMSPLERDELSFVMEFAPHG----DMKRY
. |....| |.||.  .....  |.  .||.| .  .. . .|. ..|   |.|... . .|..|||.......   .|.. .|||....|    | ..|
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFDY

LS--LHGSDL--ELDQLLDAGRQVAEALAFISSQGFVHRDVAARNVLVF-TEQPSLQVKITDFGLARVLSQHQDYYRSMSNEELAFRWMAPEAIT-HRKF
.|   ||. .  . ... .  .|....|... |.|..|||.   |.|.  . ...  |||.|||||....     .. |.      ..|||| |  ... 
ISTWRHGC-FYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

TQQSDVWSFGMMLYEFVTRGDVPFGKM----EHGGILLAIRRGLTPELPRDVP-----------------------ADIVRLCQATWTKTPEERPT-FDI
.. .|.||.| .|||... |  ||       .    .  |.| . |.|..| |                        .   ..   ..| |..|||  .|
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

LAD--M
| .  .
LQHPWF