Gene RTKC3 (M.brevicollis)

RTKC3

Species: M.brevicollis
Alias: RTKC3
External Links:
Annotation:

Classification

Group: TK
Family: RTKC

Sequence

Name Sequence Type Origin Length Description Download
RTKC3.AA Protein None 2380 None Fasta, JSON
RTKC3.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of RTKC3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NCD3G RTKC3.AA NCD3G 54-77 44 8e-06 19.34 Pfam 31-54 (54) Show / Hide 
Range on Protein: 54-77
Range on HMM: 31-54/54
Sequence Identity: 44% (11 aa)

CTYGQYVNNTDE-TCRPCPQGFYKS
|. |.|.|.||. || |||.. . .
CPEGEYSNTTDSYTCTPCPED-QWP
GCC2_GCC3 RTKC3.AA GCC2_GCC3 57-77 42 1.9e-05 20.69 Pfam 1-21 (49) Show / Hide 
Range on Protein: 57-77
Range on HMM: 1-21/49
Sequence Identity: 42% (9 aa)

GQYVNNTDETCRPCPQGFYKS
|.| |.  ..| ||| |.|..
GTYYNKGQNPCEPCPRGTYQN
TNFR_c6 RTKC3.AA TNFR_c6 54-77 26 5.910614 3.28 Pfam 1-30 (41) Show / Hide 
Range on Protein: 54-77
Range on HMM: 1-30/41
Sequence Identity: 26% (8 aa)

CTYG-QYVN-NT-D--ETCRPCPQ-GFYKS
| .| .|   |. .  . |..|.  |.| .
CPPGKTYTDWNHVPHCLSCTRCHPMGQYMV
GCC2_GCC3 RTKC3.AA GCC2_GCC3 209-243 45 5.4e-07 25.7 Pfam 1-34 (49) Show / Hide 
Range on Protein: 209-243
Range on HMM: 1-34/49
Sequence Identity: 45% (16 aa)

GEYQDKSQSSSCKVCPPGTYSNWIGRTSCTNCSAG
|.| .|.| . |  || ||| | .|..|| .|..|
GTYYNKGQ-NPCEPCPRGTYQNEEGQDSCIPCPPG
NCD3G RTKC3.AA NCD3G 102-128 28 1.1e-05 18.87 Pfam 27-54 (54) Show / Hide 
Range on Protein: 102-128
Range on HMM: 27-54/54
Sequence Identity: 28% (8 aa)

ICFNCPAGKISLEN-RTGCVDCPAGYYA
.|. ||.| .| .   . |..|| ....
DCIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKC3.AA GCC2_GCC3 158-206 28 3.5e-05 19.82 Pfam 1-49 (49) Show / Hide 
Range on Protein: 158-206
Range on HMM: 1-49/49
Sequence Identity: 28% (14 aa)

GKYQDERGQSSCKLCPKGFFNPYTGRINCDYCSAG-RFSDREGATTCPTC
| | .  . . | .||.|.. .. |.  |  |..| .  | .|.|.   |
GTYYNKGQ-NPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKC3.AA NCD3G 151-178 25 0.000101 15.99 Pfam 27-54 (54) Show / Hide 
Range on Protein: 151-178
Range on HMM: 27-54/54
Sequence Identity: 25% (7 aa)

TCLYCEPGKYQDERGQSSCKLCPKGFFN
.|. |..| |... .  .|. || ..  
DCIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKC3.AA GCC2_GCC3 85-111 39 0.000141 17.85 Pfam 10-37 (49) Show / Hide 
Range on Protein: 85-111
Range on HMM: 10-37/49
Sequence Identity: 39% (11 aa)

TCIVCPPNQYAPNEGQRICFNCPAG-KI
.|. || . | ..|||. | .||.| ..
PCEPCPRGTYQNEEGQDSCIPCPPGKTT
NCD3G RTKC3.AA NCD3G 220-246 37 0.001316 12.68 Pfam 28-54 (54) Show / Hide 
Range on Protein: 220-246
Range on HMM: 28-54/54
Sequence Identity: 37% (10 aa)

CKVCPPGTYSNWIGRTSCTNCSAGWYA
|  ||.|.|||  . ..|| |  ....
CIPCPEGEYSNTTDSYTCTPCPEDQWP
TNFR_c6 RTKC3.AA TNFR_c6 206-228 39 0.004481 13.94 Pfam 1-28 (41) Show / Hide 
Range on Protein: 206-228
Range on HMM: 1-28/41
Sequence Identity: 39% (11 aa)

CRPG-EYQDKSQ-S--SSCKVCPP-GTY
|.|| .|.|. . .   ||..|.| |.|
CPPGKTYTDWNHVPHCLSCTRCHPMGQY
GCC2_GCC3 RTKC3.AA GCC2_GCC3 125-157 45 0.010753 11.73 Pfam 1-33 (49) Show / Hide 
Range on Protein: 125-157
Range on HMM: 1-33/49
Sequence Identity: 45% (15 aa)

GYYANQGYTSCYPCPVARYQPMSGQRTCLYCEP
|.| | |   | |||   ||. .||..|. | |
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPP
TNFR_c6 RTKC3.AA TNFR_c6 155-177 27 0.047413 10.44 Pfam 1-28 (41) Show / Hide 
Range on Protein: 155-177
Range on HMM: 1-28/41
Sequence Identity: 27% (8 aa)

CEPG-KYQDERGQ-SSC---KLCPK-GFF
|.||  |.|  .. . |   ..|.. |..
CPPGKTYTD-WNHVPHCLSCTRCHPMGQY
TNFR_c6 RTKC3.AA TNFR_c6 89-106 30 0.07755 9.71 Pfam 1-19 (41) Show / Hide 
Range on Protein: 89-106
Range on HMM: 1-19/41
Sequence Identity: 30% (6 aa)

CPPN-QYAPNEGQ-RICFNC
|||. .|   ... ..| .|
CPPGKTYTD-WNHVPHCLSC
TNFR RTKC3.AA TNFR 223-254 18 0.08037 4.99 SMART 1-50 (50) Show / Hide 
Range on Protein: 223-254
Range on HMM: 1-50/50
Sequence Identity: 18% (9 aa)

CP--PGTYSNWIG-----R--TSCT--NCSA---GWYAPNNRTN----QC
|.  .|.|..  .     .  ..|.  .|.    | |.  . |     .|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
NCD3G RTKC3.AA NCD3G 82-95 42 0.444296 5.17 Pfam 41-54 (54) Show / Hide 
Range on Protein: 82-95
Range on HMM: 41-54/54
Sequence Identity: 42% (6 aa)

DDITCIVCPPNQYA
| .||. ||. |..
DSYTCTPCPEDQWP
NCD3G RTKC3.AA NCD3G 186-212 25 2.561496 2.91 Pfam 28-54 (54) Show / Hide 
Range on Protein: 186-212
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CDYCSAGRFSDREGATTCPTCRPGEYQ
|  | .| .|.  ...|| .| .... 
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKC3.AA GCC2_GCC3 263-274 41 6.425809 2.7 Pfam 38-49 (49) Show / Hide 
Range on Protein: 263-274
Range on HMM: 38-49/49
Sequence Identity: 41% (5 aa)

TSYEGATEPETC
|.|.|.| .. |
TDYPGSTSESDC
GCC2_GCC3 RTKC3.AA GCC2_GCC3 314-350 36 7.4e-07 25.26 Pfam 1-36 (49) Show / Hide 
Range on Protein: 314-350
Range on HMM: 1-36/49
Sequence Identity: 36% (14 aa)

GQIVNASHPQRKCMKCPPGTYQPYTGRTECYECPDG-R
|.  |...   .|  || ||||.. |...| .||.| .
GTYYNKGQ--NPCEPCPRGTYQNEEGQDSCIPCPPGKT
NCD3G RTKC3.AA NCD3G 326-352 33 1e-06 21.7 Pfam 28-54 (54) Show / Hide 
Range on Protein: 326-352
Range on HMM: 28-54/54
Sequence Identity: 33% (9 aa)

CMKCPPGTYQPYTGRTECYECPDGRFS
|..||.|.|.  |. ..|  ||..  .
CIPCPEGEYSNTTDSYTCTPCPEDQWP
TNFR_c6 RTKC3.AA TNFR_c6 329-349 33 4.575358 3.66 Pfam 1-26 (41) Show / Hide 
Range on Protein: 329-349
Range on HMM: 1-26/41
Sequence Identity: 33% (9 aa)

CPPG-TYQPYTG--R--TECYECPD-G
|||| ||.  ..  .  . | .|.  |
CPPGKTYTD-WNHVPHCLSCTRCHPMG
NCD3G RTKC3.AA NCD3G 310-318 55 10.578941 1.08 Pfam 30-38 (54) Show / Hide 
Range on Protein: 310-318
Range on HMM: 30-38/54
Sequence Identity: 55% (5 aa)

PCPAGQIVN
|||.|...|
PCPEGEYSN
NCD3G RTKC3.AA NCD3G 387-413 25 0.659731 4.66 Pfam 29-54 (54) Show / Hide 
Range on Protein: 387-413
Range on HMM: 29-54/54
Sequence Identity: 25% (7 aa)

TPCPANTYRRWDFSLSNCVDCPAGSSS
.|||...|   .    .|..|| .  .
IPCPEGEYSNTT-DSYTCTPCPEDQWP
GCC2_GCC3 RTKC3.AA GCC2_GCC3 369-412 26 2.471185 4.05 Pfam 1-37 (49) Show / Hide 
Range on Protein: 369-412
Range on HMM: 1-37/49
Sequence Identity: 26% (12 aa)

GYYLDPNITLNKTSDYPHTPCPANTYRRWDFSLSNCVDCPAG-SS
|.|..       .. .| .||| .||.    .   |  ||.| ..
GTYYN-------KGQNPCEPCPRGTYQ-NEEGQDSCIPCPPGKTT
TNFR_c6 RTKC3.AA TNFR_c6 389-407 35 6.583468 3.12 Pfam 1-19 (41) Show / Hide 
Range on Protein: 389-407
Range on HMM: 1-19/41
Sequence Identity: 35% (7 aa)

CPAN-TYRRWDFSLSNCVDC
|| . || .|   .. |. |
CPPGKTYTDWNH-VPHCLSC
GCC2_GCC3 RTKC3.AA GCC2_GCC3 431-454 26 0.078065 8.93 Pfam 1-26 (49) Show / Hide 
Range on Protein: 431-454
Range on HMM: 1-26/49
Sequence Identity: 26% (7 aa)

GEYW-TGS-SCSACPHGYFTDQADAV
|.|  .|.  |..||.|.. .... .
GTYYNKGQNPCEPCPRGTYQNEEGQD
TNFR_c6 RTKC3.AA TNFR_c6 428-445 26 10.693868 2.4 Pfam 1-26 (41) Show / Hide 
Range on Protein: 428-445
Range on HMM: 1-26/41
Sequence Identity: 26% (7 aa)

CVPG-EYWT-G--SSC---SACPH-G
| || .|.  .  . |   . |.. |
CPPGKTYTDWNHVPHCLSCTRCHPMG
GCC2_GCC3 RTKC3.AA GCC2_GCC3 479-499 33 0.04558 9.69 Pfam 10-30 (49) Show / Hide 
Range on Protein: 479-499
Range on HMM: 10-30/49
Sequence Identity: 33% (7 aa)

ICTACEPGKYQDQSGSTACKS
.|..|. | ||...|...|..
PCEPCPRGTYQNEEGQDSCIP
TNFR RTKC3.AA TNFR 462-497 20 0.099269 4.03 SMART 1-50 (50) Show / Hide 
Range on Protein: 462-497
Range on HMM: 1-50/50
Sequence Identity: 20% (10 aa)

CV--PGQHQNVSYTT---SSDRICT--ACEP---GKYQDQSGST----AC
|   .|.... .  |   .  . |.   |.|   |.|  |...      |
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
NCD3G RTKC3.AA NCD3G 479-499 28 0.135701 6.7 Pfam 27-47 (54) Show / Hide 
Range on Protein: 479-499
Range on HMM: 27-47/54
Sequence Identity: 28% (6 aa)

ICTACEPGKYQDQSGSTACKS
.|. |..| |.....|. |..
DCIPCPEGEYSNTTDSYTCTP
TNFR_c6 RTKC3.AA TNFR_c6 483-499 36 0.412579 7.23 Pfam 1-18 (41) Show / Hide 
Range on Protein: 483-499
Range on HMM: 1-18/41
Sequence Identity: 36% (7 aa)

CEPG-KYQDQSGS-TACKS
|.||  |.| ..    |.|
CPPGKTYTD-WNHVPHCLS
TNFR_c6 RTKC3.AA TNFR_c6 542-580 38 0.000198 18.57 Pfam 1-41 (41) Show / Hide 
Range on Protein: 542-580
Range on HMM: 1-41/41
Sequence Identity: 38% (16 aa)

CPEG-KYQDQWHQ-PSCKNTTICLP-GQYQVTTPSVRRDRRC
||.|  |.| |.. | |.. | | | ||| |      ... |
CPPGKTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR RTKC3.AA TNFR 542-580 26 0.001511 19.03 SMART 1-50 (50) Show / Hide 
Range on Protein: 542-580
Range on HMM: 1-50/50
Sequence Identity: 26% (13 aa)

CP--EGKYQDQWHQ----PSCKNTT--ICLP---GQYQVTTPSVRRDRRC
|.  || |...|..    | |.  .   | |   ||| .   .  ....|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
GCC2_GCC3 RTKC3.AA GCC2_GCC3 525-558 35 0.123685 8.28 Pfam 1-30 (49) Show / Hide 
Range on Protein: 525-558
Range on HMM: 1-30/49
Sequence Identity: 35% (12 aa)

GTYAHEWVAEKPADCRACPEGKYQDQWHQPSCKN
||| .   ..  . | .|| | ||..  | ||..
GTYYN---KGQ-NPCEPCPRGTYQNEEGQDSCIP
NCD3G RTKC3.AA NCD3G 538-550 53 11.168579 1.01 Pfam 27-39 (54) Show / Hide 
Range on Protein: 538-550
Range on HMM: 27-39/54
Sequence Identity: 53% (7 aa)

DCRACPEGKYQDQ
||  |||| |...
DCIPCPEGEYSNT
TNFR RTKC3.AA TNFR 583-621 24 0.227503 0.26 SMART 1-50 (50) Show / Hide 
Range on Protein: 583-621
Range on HMM: 1-50/50
Sequence Identity: 24% (12 aa)

CP--EDRLTPFENEL----RCDYPE--LCPS---GWGVTQEFTTSSERVC
|.  |.  .  .|..    .|       ||.   | ...|. |  | .||
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC3.AA TNFR_c6 624-651 29 35.938629 0.6 Pfam 1-28 (41) Show / Hide 
Range on Protein: 624-651
Range on HMM: 1-28/41
Sequence Identity: 29% (9 aa)

CVLGVTYNDDPDG--GVCKPVNASCPP-GTG
|  |.||.|  ..    |..  ..|.| |..
CPPGKTYTD--WNHVPHCLSC-TRCHPMGQY
TNFR RTKC3.AA TNFR 667-705 22 0.004944 17.32 SMART 1-50 (50) Show / Hide 
Range on Protein: 667-705
Range on HMM: 1-50/50
Sequence Identity: 22% (11 aa)

CP--SNAFKPHWGD----ENCTHAT--ICDV---RERETTPITPTSDRVC
|.   . .  ||..    . |.  .   |.     .... | |.||..||
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC3.AA TNFR_c6 667-705 26 0.167214 8.57 Pfam 1-41 (41) Show / Hide 
Range on Protein: 667-705
Range on HMM: 1-41/41
Sequence Identity: 26% (11 aa)

CPSN-AFKPHWGD-ENCTHATICDV-RERETTPITPTSDRVC
|| .  .   |.  . |.  | |.   .... | |.|...||
CPPGKTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
HYR RTKC3.AA HYR 1241-1319 32 5.5e-09 31.62 Pfam 5-86 (86) Show / Hide 
Range on Protein: 1241-1319
Range on HMM: 5-86/86
Sequence Identity: 32% (27 aa)

PSWV-GCPVAPIEVNMPAGLDQVQAIWIEPQAKDNVG---ISRIDATFRPGDNFSWIGNPYQIVYTAYDLSEQSA-ECRFDLQI
|. |  ||   |.   . |   |. .| || |.|| |   ...|  |  |||.|.. |  . . ||..| .. .| .| |.  .
PPTVENCPNN-IFRTVELGTSTVNVFWTEPTATDNSGDIQANLISRTAQPGDFFPV-GEQTTVTYTFQDNAGNQADTCTFTVTV
HYR RTKC3.AA HYR 1543-1580 34 0.002208 13.16 Pfam 1-38 (86) Show / Hide 
Range on Protein: 1543-1580
Range on HMM: 1-38/86
Sequence Identity: 34% (13 aa)

YDNQKPTFLSCPSSAATRAPINVSFATFNWTEPAITDN
 | . ||...||.. .  .... | .   ||||. |||
VDTTPPTVENCPNNIFRTVELGTSTVNVFWTEPTATDN
HYR RTKC3.AA HYR 1725-1805 30 1.3e-13 46.85 Pfam 1-86 (86) Show / Hide 
Range on Protein: 1725-1805
Range on HMM: 1-86/86
Sequence Identity: 30% (27 aa)

IDEEAPNV-ICPSNVVAFVTANDEG-NATWDAPVVVDNAG---AEGLTWTSEVANGSSFGLG-SHLVRIDAYDASGNKA-SCQFAVTM
.| . | |  ||.|... |. .. . | .|. | . ||.|   |.  . |..  .|..|. | .. |.  ..|..||.| .|.| || 
VDTTPPTVENCPNNIFRTVELGTSTVNVFWTEPTATDNSGDIQANLISRTAQ--PGDFFPVGEQTTVTYTFQDNAGNQADTCTFTVTV
HYR RTKC3.AA HYR 1641-1724 28 1e-06 23.64 Pfam 1-86 (86) Show / Hide 
Range on Protein: 1641-1724
Range on HMM: 1-86/86
Sequence Identity: 28% (25 aa)

QDGQPPNA-VCPQDLEYTLLPGRAEYDVPYSAWRPTTTDNAD--LAVVVLQPEAGASMPLPTG-AHEFVVVVQDAWGNNG-SCTGTVTI
.| .||    ||   ..|  .|  .  |...   || |||..   |.....     .. .|.|  ..   ..||. ||.. .|| |||.
VDTTPPTVENCPNNIFRTVELGTSTVNVFWTE--PTATDNSGDIQANLISRTAQPGDF-FPVGEQTTVTYTFQDNAGNQADTCTFTVTV
HYR RTKC3.AA HYR 1619-1640 43 0.004731 12.07 Pfam 64-86 (86) Show / Hide 
Range on Protein: 1619-1640
Range on HMM: 64-86/86
Sequence Identity: 43% (10 aa)

TVQYRARDEYGNFA-LCNFTLRA
||.| ..|. || |  |.|| . 
TVTYTFQDNAGNQADTCTFTVTV
Kinase RTKC3.AA RTKC 1884-2144 75 2.2e-227 757.7 In-house 1-261 (261) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-261/261
Sequence Identity: 75% (198 aa)

VKLLDELGRGAFGIVYKALLEEPG-MPGYIVACKSLHEANQGGAMRELLEEAAVTAQFVHPNVVHLIGVVSVGKPLLVVLGFCERGSLKSYLEENGPMVS
..|||||||||||||||||||||| ||||.|||||||.........||||||||.|||.|||||||||||.||||.||||.|||||||||||..|. ...
LTLLDELGRGAFGIVYKALLEEPGGMPGYLVACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYLMNNP-DCT

DEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSHAAYYRSRSGNLPVRWSAPEALEDQKFSHASDSWGFGILMYE
..|...|..||||||||..||||||||.||||.||.|||.|||.|||||||||..||||.||||||||||||||.|||||.|.|||..||.|.|||||||
EHQKVRFCYQCASGMEHIHSFGFIHRDVAARNVLLSSDLTCKVADFGLARESPCNDDSHEAYYRSRSGNLPVRWTAPEALDDRKFSEKSDVWAFGILMYE

IYTDAEMPYKGWSNQRVWVEVSAGFRLPRPETCHESVYEIMMDCWMHTPADRPTFSDIVFEL
|||.|||||.|||||||||||.||.|||.||.||..||..|||||||||.||||||..|..|
IYTKAEMPYDGWSNQRVWVEVCAGYRLPCPEDCHKEVYDMMMDCWMHTPHDRPTFSEVVHWL
Kinase RTKC3.AA TK 1884-2144 22 1.7e-109 368.35 In-house 1-486 (486) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

VKLLDELGRGAFG---IVYKALLEEPG----------------------MPGYIVACKSLHEANQGGAMRELL-------------EEAAVTAQFV----
..|...||.|.||    |||.......                      .    || | |.| .   ......             |||.. ...     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVHLIGVVSVG------------KPLLVVLGFCERGS----LKSYLEENGP---------------------------------------------
 |||.|.|.||.. |            .|...|. ... |.    |..|| .. |                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------MVSDEQRAYFAFQCASGMEHVASF------GFIHRDIAARNILLASDLS-----------CKVSDFG---
                               .. .|.  ...| |.|||. .|       .|.|||.||||.|.....            ||..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARESPNTDDSHA-------------------AYYRSRSG-NLPVRWSAPEALEDQK---------FSHASDSWGFGILMYEIYTDA-EMPYKGW
     |||. .. || ..                   .|||..||  ||.|| |||.|.|..         |...|| | ||.||.||.| . |..| |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SNQRVWV-----------------------EVSAGFRLPRPETCH--------------ESVYEIMMDCWMHTPADRPTFSDIVFEL
|||.||.                       ||  ..|.|.|. |.              | .|..|..|| . |.||||||... .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKC3.AA RTKD 1884-2146 43 2.9e-108 365.97 In-house 1-262 (262) Show / Hide 
Range on Protein: 1884-2146
Range on HMM: 1-262/262
Sequence Identity: 43% (115 aa)

VKLLDELGRGAFGIVYKALLEE---PGMPGYIVACKSLHEANQGGAMRELLEEAAVTAQFVHPNVVHLIGVVSVGKPLLVVLGFCERGSLKSYLEENGPM
.|.|. .| | .|.| ||.|||    |.|| .|| | .  ..|  .. |.. |||  ||| |.|.| | ||| . .|   |  .|| ||| .|| |||  
IKCLEPIGKGNWGMVFKAMLEEHIMKGIPGFLVAVKIMKNQSQ-EQVMEMTREAAFMAQFNHDNIVRLHGVVTTNQPHIMVMEYCEHGSLQAYLRENGED

VSDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSHAAYYRSRSGNLPVRWSAPEALEDQKFSHASDSWGFGILM
.   .|  .|   | | . ..  | .||||||||||| |..  |. |||| |  .| |    .|| |. .  ||||.|||.||. |||.||| |  ....
MDNQHRFRMARDVAMGLAYLHFRGCCHRDIAARNILLDSNYRAKIGDFGLTRQQANGD---SEYYISHGQAIPVRWCAPEVLEEHKFSQASDVWSWAVFV

YEIYTDAEMPYKGWSNQRVWVEVSAGFRLPRPETCHESVYEIMMDCWMHTPADRPTFSDIVFELRG
||| | |..||.. .||.||  | .|.||.||. | . ....|||||   |..||..  .|  .  
YEIWTQAQLPYRDMHNQKVWHYVIQGYRLTRPMQCPRDIWALMMDCWAEDPKERPRMCQVVDQMTK
Kinase RTKC3.AA Pkinase_Tyr 1884-2144 36 3.9e-108 366.84 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-270/270
Sequence Identity: 36% (101 aa)

VKLLDELGRGAFGIVYKALLE-EPGMPGYIVACKSLHEANQGGA--MRELLEEAAVTAQF-VHPNVVHLIGVVS-VGKP--LLVVLGFCERGSLKSYLEE
.... .||.|||| |||. .  .|. ... || |.| |     .  ......||..  |.  |||.| |.||..  |.|  ...|. ... |.|..|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N---GPMVSDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSHAAYYRSRSGNLPVRWSAPEALEDQKFSHASDS
.   .. .. ..   ...| |.|||. .| ..||||.||||.|..... .|..||||||    ..|.   |. . .| ||..| |||.. . ||...|| 
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDV

WGFGILMYEIYTDAEMP-YKGWSNQRVWVEV-SAGFRLPRPETCHESVYEIMMDCWMHTPADRPTFSDIVFEL
| ||.||.||.|  |.| |.|.||..|   .   | |.|.|| |.. .|..|..||.. |.||||||.|. .|
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKC3.AA TyrKc 1884-2144 36 3.1e-106 360.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-280/280
Sequence Identity: 36% (105 aa)

VKLLDELGRGAFGIVYKALLEEPGMPGYIVACKSLHEANQGGAMRELLEEAAVTAQF--VHPNVVHLIGVVSVG-------KPLLVVLGFCERGSLKSYL
..|...||.||||.|||. .       . || |.|.|      ......|| .  ..   |||.| |.||.. .       .||..|. ... |.||.||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

EENGPMVSDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDS--HAAYYRSR---SGN--LPVRWSAPEALEDQKF
 ...| .. ..  .|..| |.|||. .| ..||||.||||.|..... .|.|||||.|.  . | .     |||..   .|.  ||.|| |||.. . ||
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SHASDSWGFGILMYEIYTDAEMPYKG-----WSNQRVWVEVSAGFRLPRPET--------CHESVYEIMMDCWMHTPADRPTFSDIVFEL
...|| | ||..|.||.|. ..|| |      |||.|   | .|.|.|.|.         |.. .|.|| .||.. |.||||||.|. ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKC3.AA UTK 1884-2144 34 2.3e-103 349.7 In-house 1-296 (296) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-296/296
Sequence Identity: 34% (103 aa)

VKLLDELGRGAFGIVYKALLEEPG--MPGYIVACKSLH-EANQGGAMR---ELLEEAA---VTAQFV-HPNVVHLIGVVSVGKPLLVVLGFCERGSLKSY
|.|...||.||||.|.|| ....   |.  .|| | .  .|.   ...   ...|||.   . .||  ||||. |.||.. ..|...|. ..|.|.| ||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LEENGP-------MVSDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASD-------LSCKVSDFG---LARESPN----TDDSHAAYYRSR-SGN
|  ..|       .....|| ..| . |.||.. .| ||.|||.||||.|....       ..||..|||   ..|. ..    . .. . ||...  . 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVRWSAPEALEDQ-KFSHASDSWGFGILMYEIYTDAEMPYKGWSNQRVWVEVSAG--FRLPRPETCHESVYEIMMDCWMHTPADRPTFSDIVFEL
.|.|| ||||| .. .|...|| | ||....||.| . .||.|.||..||..|..|   |.|.|. | ..||..|..||. .|..||.| |.| ..
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKC3.AA Eph 1884-2144 39 1.8e-84 283.69 In-house 1-264 (264) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-264/264
Sequence Identity: 39% (105 aa)

VKLLDELGRGAFGIVYKALLEEP-GMPGY---IVACKSLHEANQGGAMRELLEEAAVTAQFVHPNVVHLIGVVSVGKPLLVVLGFCERGSLKSYLEENGP
.|.   .| | || |..  |  | |       .|| | | .     . .. | ||..  || |||...| |||. ..|. .|  . | ||| |.| ..  
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

MVSDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSHAAYYRSRSGNLPVRWSAPEALEDQKFSHASDSWGFGIL
 ..  |        ||||   ......||| ||||||. |.| |||||||| |. .  |.|  | | .|.|  |.|| ||||.   ||. ||| | .||.
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRV-LEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIV

MYEIYTDAEMPYKGWSNQRVWVEVSAGFRLPRPETCHESVYEIMMDCWMHTPADRPTFSDIVFEL
| |. .  | ||  .||| |  ..  |.||| |  | |. ...|.|||   ...||.|..||  |
MWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase RTKC3.AA Src 1884-2144 36 2.8e-77 262.08 In-house 1-255 (255) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-255/255
Sequence Identity: 36% (96 aa)

VKLLDELGRGAFGIVYKALLEEPGMPGYIVACKSLHEANQGGAMRELLEEAAVTAQFVHPNVVHLIGVVSVGKPLLVVLGFCERGSLKSYLE--ENGPMV
.||...||.| || |....          || |.| ...   .   .|.|| .  .. |...|.|  |.| ..| . |  . ..|||  ||   . |  .
IKLCRKLGQGQFGEVWMGYWNG----NTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL

SDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSHAAYYRSRSGNLPVRWSAPEALEDQKFSHASDSWGFGILMY
. .|  ..| | |.||.   |  .|||| ||||.|   .. ||| ||||||   . ||    |  .   ..|..| ||||.  ..|.  || | ||||..
HLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDD---EYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLT

EIYTDAEMPYKGWSNQRVWVEVSAGFRLPRPETCHESVYE-IMMDCWMHTPADRPTFSDIVFEL
|| |   .||.|..|. |  .|..|.|.|.|..| ...|| ||. ||  .| .||||  .   |
EIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase RTKC3.AA TK-Unique 1884-2144 30 3.2e-72 246.25 In-house 1-294 (294) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-294/294
Sequence Identity: 30% (90 aa)

VKLLDELGRGAFGIVYKALLEEPG---MPGYIVACKSLHEANQGGAMRELLEEAAVTAQFV-HPNVVHLIGVVSVGK-PLLVVLGFCERGSLKSYLEENG
....|..|.|||| |... ....        .|| | |.. ...   ...| |...  .   |||.|...|.      | . .. .|..|.| .|| ...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

----------------------PMVS--DEQRAY-FAFQCASGMEHVAS--FGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSHAAYYRSRS-G
                      |. .  .... | ||.|.|.|||. ||   ...|||..|||.||..|. ||..|||.||.  .    . .| ...| |
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT----NGVYSMMCSQG

NLPVRWSAPEALE--DQKF-SHASDSWGFGILMYEIYTDAEMPYKGWSNQRVWVEVSAGFRLPRPETC-HESVYEIMMDCWMHTPADRPTFSDIVFEL
 .|.|| |||.|   .. . .  || | ||.||.|| |  ..|| | .. ..  .. .|.|.|.|| |  . .|..|  || . | .||.|..|...|
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKC3.AA Fer 1884-2145 32 8.2e-72 243.82 In-house 1-283 (283) Show / Hide 
Range on Protein: 1884-2145
Range on HMM: 1-283/283
Sequence Identity: 32% (94 aa)

VKLLDELGRGAFGIVYKA-----LLEEPGMPG--YIVACKSLHEANQGGA-MRELLEEAAVTAQ-FVHPNVVHLIGVVSVGKPLLVVLGFCERGSLKSYL
|.| . ||.||||.|||.     .. . .. .    |. | ....  . . ..|.. || .  . . ||||| ..|| .   |...|. ||  |||.|||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

EENGP-MVSDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLAS-DLSCK--VSDFGLARESPNTDDSHAAYYRS-RSGNLPVRWSAPEALEDQKFSH
 .|.   ||| ..  ...| |.|||.  | . |||||||||.|.   .. .|  .||||..|.   ..|   .|.    .  .|.|| |||....  .|.
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQ---CSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSP

ASDSWGFGILMYEIYTDAEMPYKG---------WSNQRVWVEVSAGFRLPRPETCHESVYEIMM-DCWMHTPADRPTFSDIVFELR
..| | ||....||.|... || |         . .|.. . . .| ..| |. ... ...||| .|| . | ||||...|. .|.
KTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase RTKC3.AA CTKA 1884-2144 34 8.4e-69 230.27 In-house 1-290 (290) Show / Hide 
Range on Protein: 1884-2144
Range on HMM: 1-290/290
Sequence Identity: 34% (101 aa)

VKLLDELGRGAFGIVYKALLEEPGMP--------GYIVACKSLHEANQGGAMRELLEEAAVTA--QFVHPNVVHLIGVVSVGKPLLVVLGFCERGSLKSY
     ..| | .| |..|.|  |  .        |  || |.| .    .. |. | || | .  .| ||||. |.||.   ||.. .  .   | |..|
HCIMFKIGEGHYGQVFRAWL-MPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCY

LEENGPMV----------------------SDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSH-AAYYRSRSG
|    |                          ||  | | | | ||.  |. ||.||| |.||.|| .    |..|||..|    | ..    || | ..
LRACRPADGQVCPARARRSIPRSFHPIEVHAHEQ-VYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGR----TLRTESQYYYVSSQR

NLPVRWSAPEALEDQKFSHASDSWGFGILMYEIYTDAEMPYKGWSNQRVWVEVSAG--FRLPRPETCHESVYEIMMDCWMHTPADRPTFSDIVFEL
 .|||| |||||   ||| ||| | ||.|..|| . .| |. . | | |   . ..   ||| | .| . .|  |  ||   |. ||||  .  .|
VMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase RTKC3.AA Tec 1884-2146 35 1.3e-66 227.66 In-house 1-254 (254) Show / Hide 
Range on Protein: 1884-2146
Range on HMM: 1-254/254
Sequence Identity: 35% (95 aa)

VKLLDELGRGAFGIVYKALLEEPGMPGYIVACKSLHEANQGGAMRE--LLEEAAVTAQFVHPNVVHLIGVVSVGKPLLVVLGFCERGSLKSYLEENGPMV
 ... |||.| ||.|  . .       | || | . |    |.| |   .||| |     ||. | | || |  .|. .|  . |.|.| .|| |.. . 
LTFMKELGSGQFGVVHLGKWRH----QYDVAIKMIKE----GSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHF

SDEQ--RAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSHAAYYRSRSGNLPVRWSAPEALEDQKFSHASDSWGFGIL
. ..    .   .   ||.   . .||||| |||| |  ..   ||||||..|     ||    |  |     ||.|..|| .   ..|  || | ||.|
QKNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYV--LDD---QYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVL

MYEIYTDAEMPYKGWSNQRVWVEVSAGFRLPRPETCHESVYEIMMDCWMHTPADRPTFSDIVFELRG
| |...   |||   ||  |  .|| |.|| ||. | ...|.|| .|| . | .||||..   ..  
MWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase RTKC3.AA S_TKc 1884-2142 22 8.7e-38 132.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 1884-2142
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

VKLLDELGRGAFGIVYKALLEEPGMPGYIVACKSLHEANQGGAMRELLEEAAVTAQFVHPNVVHLIGVVSVGKPLLVVLGFCER--GSLKSYLEENGPM-
 ..|...|.|||| |||.   .    | |||.| ..        . .. | ..  .  |||.|.|..|    . | .|. .|.   |.|..|....|.  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----VSDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSCKVSDFGLARESPNTDDSHAAYYRSRSGNLPVRWSAPEALEDQKFSH-ASDSWG
     .  . .... | ....|.  | |.||||.   |||| .    |..||||||.              ..      . ||| |   .... ..| | 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWS

FGILMYEIYTDAEMPYKGWSNQRVWVEVSAGFRLPRPETCHESVYEIMMDCWMHTPADRPTFSDIV-----------F
.|...|| ..  . |.    .. .  ..             ... .... |.   |..|||  ..            |
CGCILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKC3.AA Pkinase 1884-2141 22 2.8e-31 111.67 Pfam 1-288 (293) Show / Hide 
Range on Protein: 1884-2141
Range on HMM: 1-288/293
Sequence Identity: 22% (66 aa)

VKLLDELGRGAFGIVYKALLEEPGMPGYIVACKSLHEANQGGAMRELLE---EAAVTAQFVHPNVVHLIGVVSVGKPLLVVLGFCERG----SLKSYLE-
 ...  .|.|.|| |||.     |    |||.| .   ..   ... .    |... . . |||.| |....  .. . .|. .|| |    .|..|.. 
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-ENGPM-VSDEQRAYFAFQCASGMEHVASFGFIHRDIAARNILLASDLSC----KVSDFGLARE-SPNTDDSHAAYYRSRSGNLPVRWSAPEALE-DQKF
 ..|..  |...   .. | ..|.|.  | |.||||.   |||. ..  .    |..|||||.  .      .   . .. | .  .. ||| .  .|. 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTP--WYMAPEVIRGGQYY

SHASDSWGFGILMYEIYTDAEMPYKGW-------SNQRVWVEVSAGFRLPRPETCH-------------------ESVYEIMMDCWMHTPADRPTFSDIV
....| |..|...|| ..  . |..|         .|..    .. .. ..|..|                    |.  ... .|.   |..|||. .|.
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL
CAP_GLY RTKC3.AA CAP_GLY 2311-2377 50 9.1e-25 87.77 Pfam 1-72 (72) Show / Hide 
Range on Protein: 2311-2377
Range on HMM: 1-72/72
Sequence Identity: 50% (36 aa)

VGRRVRV--QGYACQGTLRYYGPHQ-SKPGKRCGVEL-DEPLGLNNGTVAGHKYFEC-APSHGVLVVPLRVE
|| |..|  .|  . ||.||.|| .  |||  .|||. |||.| |.|.| | .||||  | ||. | | .||
VGDRCEVWDGGGGRRGTVRYVGPTPGFKPGTWVGVEWDDEPRGKNDGSVQGVRYFECRPPNHGIFVRPSKVE