Gene Src3 (M.brevicollis)

Src3

Species: M.brevicollis
Alias: Src3
External Links:
Annotation:

Classification

Group: TK
Family: SFK-Src

Sequence

Name Sequence Type Origin Length Description Download
Src3.AA Protein None 473 None Fasta, JSON
Src3.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of Src3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 Src3.AA SH3 30-87 37 3.2e-19 71.1 SMART 1-58 (58) Show / Hide 
Range on Protein: 30-87
Range on HMM: 1-58/58
Sequence Identity: 37% (22 aa)

RILLAMYEYQARTDEDLTFHQGTHLELLDDSDANWWKARSLTTNQVGFIPCNYVAEES
.   |.| |||.....|.|..|  ...|...| .|||.|  .|.|.|..|.|||.|  
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 Src3.AA SH3_1 33-80 36 6.3e-17 60.05 Pfam 1-49 (49) Show / Hide 
Range on Protein: 33-80
Range on HMM: 1-49/49
Sequence Identity: 36% (18 aa)

LAMYEYQARTDEDLTFHQGTHLELLDDSDA-NWWKARSLTTNQVGFIPC
 | | |||.....|.| .|  ......||. .|||.|...|.|.|..|.
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 Src3.AA SH3_2 31-86 17 4.7e-07 27.58 Pfam 1-68 (68) Show / Hide 
Range on Protein: 31-86
Range on HMM: 1-68/68
Sequence Identity: 17% (12 aa)

ILLAMYEYQA-RTDED-----LTFHQGTHLELL---DDSDANWWKA-RSLTTNQV--GFIPCNYVAEE
   .. .|.. .  ..     |.|. |  ....   | .. |||.. ........  |..| ..|.| 
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 Src3.AA SH2 94-171 43 3.2e-28 84.7 Pfam 1-81 (81) Show / Hide 
Range on Protein: 94-171
Range on HMM: 1-81/81
Sequence Identity: 43% (35 aa)

WYHGKLERAEAQRLLTS--QPHGSFLVRLSSDGQ-SYALSIRLIGADIDYKHYRVRKMENGDFFIASRVIKPSITTLINHY
|||||. |.||.||| .  .|.|.|||| |.  . .|.|| |  |     ||||.....|| ..|. |.  .|.  |..||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 Src3.AA SH2 92-177 40 6e-27 96.76 SMART 1-87 (87) Show / Hide 
Range on Protein: 92-177
Range on HMM: 1-87/87
Sequence Identity: 40% (37 aa)

EPWYHGKLERAEAQRLLTS--QPHGSFLVRLSSD-GQSYALSIRLIGADIDYKHYRVRKMENGDFFIAS--RVIKPSITTLINHYQQQADG
.|||||.. |.||..|| .  .|.|.|||| |.   ..|.||.|       .||||.|. ..| ..|.   |.  ||.  |.||||. ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK---GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase Src3.AA SFK-Src 210-466 79 9.40000000001e-250 749.41 In-house 1-259 (259) Show / Hide 
Range on Protein: 210-466
Range on HMM: 1-259/259
Sequence Identity: 79% (206 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGAMSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYLHE-HGRGLTVQQLVD
||||.|||.||||.||||||||.|.||||||||||||..|||.||..||||||.||||||||||||||.|||.|||.|||||||||| |||.|...||||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLENDDI-YEAHQGAKFPIKWTAPEAANYNRFSTKSDVWAFGILMMEIITLGRVPY
|.||.|.||||||.||||||||||||||||||||||||||||||.|..||. |.||.|||||||||||||.|.||||.|||||.||||||||.|.||.||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMSNAEVLRRVDVPEKYRMPKPQNCPDEYHAIMFACWQHEADDRPLFESLKVQLEDFA
|||.|.|||..||.||.||||.|.||||||..|||.|||||.||||.|||||.|.||| 
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase Src3.AA Src 210-462 63 3.2e-169 568.47 In-house 1-255 (255) Show / Hide 
Range on Protein: 210-462
Range on HMM: 1-255/255
Sequence Identity: 63% (164 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGAMSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYLH--EHGRGLTVQQLV
|.|.||||.|||||||.| ||..|.||||||||| || . || || ||||||| .|.||||||...|| ||. |.|. |||||||.  . || | ..||.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLE-NDDIYEAHQGAKFPIKWTAPEAANYNRFSTKSDVWAFGILMMEIITLGRVP
||.||.|.|||||| .|..||||||||||||.||||||.|||  | .. .||.|.|..|||||||||||||.||.||..||||| ||||..||.| ||||
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMSNAEVLRRVDVPEKYRMPKPQNCPDEYHA-IMFACWQHEADDRPLFESLKVQL
||||.|.|||..|.    ||||.|.||||| .  ||  ||. ....|| || |   |
YPGMTNHEVLQQVE--RGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Src3.AA Pkinase_Tyr 210-462 50 2e-149 506.69 Pfam 1-270 (270) Show / Hide 
Range on Protein: 210-462
Range on HMM: 1-270/270
Sequence Identity: 50% (138 aa)

IRLERKLGAGQFGEVWKGRWN-----NSTDVAVKTLKPGAMSS----DEFLSEAAIMKKL-RHTNLIQLYAVCT-DGEP--MYIISELMRYGSLLDYLHE
|.. .|||.|.||||.||.|.     . ..||||.||.|||..    ..|..||.|||.| .| |...||.||| .|||  .||. |.| .|.|||||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H---GRGLTVQQLVDMTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLENDDIY-EAHQGAKFPIKWTAPEAANYNRFSTKSDVWAF
|   .. ||...|..| .|||.||.||| .|..||||||||.||..|||.|..|||..| ..||| |  ...|.|.||||.|||. ||..|.||||||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILMMEIITLGRVP-YPGMSNAEVLRRV-DVPEKYRMPKPQNCPDEYHAIMFACWQHEADDRPLFESLKVQL
|.|| ||.|.|. | ||||||.||.... .    ||||.|.||||| . .|  ||.....||| |. .  ||
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYED--GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Src3.AA Frk 210-466 64 2e-145 489.4 In-house 1-260 (260) Show / Hide 
Range on Protein: 210-466
Range on HMM: 1-260/260
Sequence Identity: 64% (168 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGAMSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYLH---EHGRGLTVQQL
|.| |.||.||||||| |.|||.| |||||||||.|  ..|| || |||||||. |||||||||  ||.||| |||| |||..||    ..|| . .|||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDMTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSR--GLENDDIYEAHQGAKFPIKWTAPEAANYNRFSTKSDVWAFGILMMEIITLGR
|||.||.|.|||||| ||..||||||||||||..|.||. |||. |    .| ||||...||.||||||||||||||.|..|||||.||||..|||| ||
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

VPYPGMSNAEVLRRVDVPEKYRMPKPQNCPDEYHAIMFACWQHEADDRPLFESLKVQLEDFA
.||||| |||||  ||  . ||||.| ||| ..  ||  ||..... || || |. .|||. 
MPYPGMTNAEVLQMVD--HGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase Src3.AA TyrKc 210-462 44 4.6e-140 472.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 210-462
Range on HMM: 1-280/280
Sequence Identity: 44% (128 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGAMSSDEFLSEAAIMKKL--RHTNLIQLYAVCTDG-------EPMYIISELMRYGSLLDYLHEHGRG
|.|..||| |.||||.||.|.  ..||||.||..|    .|..|| ||.||  .| |...||.|||..       ||..|. |.| .|.|.|||..|.. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LTVQQLVDMTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLEND-------DIYEAHQ--GAK--FPIKWTAPEAANYNRFSTKSDV
|....|...  |||.||.||. .|..||||||||.|||.|...|..|||.|| ...|       | | . .  |.|  .||.|.|||. ||..|.|||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WAFGILMMEIITLGRVPYPG-----MSNAEVLRRVDVPEKYRMPKPQN--------CPDEYHAIMFACWQHEADDRPLFESLKVQL
|.||..| || |.|  ||||     |||.||...|.  . ||||.|.|        |||| . ||  ||.....||| |. .. ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK--QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Src3.AA Src-Unclassified 210-462 50 4.4e-137 461.7 In-house 1-284 (284) Show / Hide 
Range on Protein: 210-462
Range on HMM: 1-284/284
Sequence Identity: 50% (145 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPG---AMSSDEFL--------SEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYLHEHG
..| |||| |||||||.| | .. ||||||..||    ||   ||         ||.||||.|| ||..|||||.. || ||| |.|  ||||..| | |
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

-RGLTVQQL------------VDMTAQIASGMAYLEGQNFVHRDLAARNVLVGDNN-----VCKVGDFGMSR-GLENDDIYEAHQGAKFPIKWTAPEAAN
 . |  | .            ||. ||.|||| |||    |||||||||||.|.||     | || |||  |  |  ||.|.. .||.||.||.|||.. 
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YNRFSTKSDVWAFGILMMEIITLGRVPYPGMSNAEVLRRVDVPEKYRMPKP--QNCPDE-YHAIMFACWQHEADDRPLFESLKVQL
|  ||.||||| .||| .|| |.|..||||| | |||  |     ||||||  . |||  |  ||  ||    . || |. |   .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERG--YRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase Src3.AA SrcA 210-462 59 1.9e-136 433.9 In-house 1-250 (250) Show / Hide 
Range on Protein: 210-462
Range on HMM: 1-250/250
Sequence Identity: 59% (151 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGAMSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYLHEH-GRGLTVQQLVD
|||||.|| |.||||| | || .| ||.|||||| || . || || |||||||  |.|||||  . ||.||. | | .|||||.| .. |. | . ||||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSE-EPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

MTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLENDDIYEAHQGAKFPIKWTAPEAANYNRFSTKSDVWAFGILMMEIITLGRVPYP
|.||.|.||||.|  |..|||| | |.|||.| .||. |||. | | .|. |.|.||||||||||||||| | ||  |||||.||||. |..| ||||||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLAR-LIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMSNAEVLRRVDVPEKYRMPKPQNCPDEYHAIMFACWQHEADDRPLFESLKVQL
|| | |||  |.  . |.|| ||.||   | .|  ||. . ..|| || |.  |
GMNNREVLEQVE--RGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase Src3.AA TK 210-462 28 3e-130 439.01 In-house 1-486 (486) Show / Hide 
Range on Protein: 210-462
Range on HMM: 1-486/486
Sequence Identity: 28% (141 aa)

IRLERKLGAGQFG---EVWKG------RWNNS--------------------TDVAVKTLKPG-AMSSDE--------------FLSEAAIMKKLR----
|.|..|||.||||   ||.||      .||..                    |.||||.||.| |||..|              ||.||..||...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HTNLIQLYAVCTDG------------EPMYIISELMRYGS----LLDYLHEHGRG--------------------------------------------
 | |...||.|||.|            ||..|. |.| .|.    |.|||... ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTVQQLVDMTAQIASGMAYLEGQ------NFVHRDLAARNVLVGDNNV-----------CKVGDFGMS-
                               ||..||. | .|||.||.||. .      |||||||||||.|||.|||           ||..|||.| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RGLENDDIYEAHQ------------------------GAKFPIKWTAPEAAN---------YNRFSTKSDVWAFGILMMEIITLGRVPYPG-M
       | ...|| | ...                        |.|.||.|.|||. |         |..|.||||||.||.|| || |.|..||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN---------AEVLRRVDVP------------EKYRMPKPQNCP--------------DEYHAIMFACWQHEADDRPLFESLKVQL
||         .||....               ...|||.|..||              .||. .|  ||.....||| |. |. ||
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Src3.AA SrcB 210-463 54 8.10000000001e-123 414.32 In-house 1-251 (251) Show / Hide 
Range on Protein: 210-463
Range on HMM: 1-251/251
Sequence Identity: 54% (140 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGAMSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYLH-EHGRGLTVQQLVD
..|..||||||||||| | .||.. |||||.|.|.|| . || || .||.| |  |..|||| |  ||.||| | |  |.|||.|  . |  |.. .|.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTK-EPIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLENDDIYEAHQGAKFPIKWTAPEAANYNRFSTKSDVWAFGILMMEIITLGRVPYP
|.|||| ||||.| .|..|||| | |.|| .  .||. |||. | .| |. | |. ||||||||||||| |.  |  |||||.||||.|||.| ||.|||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIE-DNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMSNAEVLRRVDVPEKYRMPKPQNCPDEYHAIMFACWQHEADDRPLFESLKVQLE
||.|.||.| ..  . ||||.|.|||.|   ||  ||.. ...|| |. |.  |.
GMTNPEVIRNLE--RGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase Src3.AA Src-Echino1 210-462 55 4.6e-120 405.19 In-house 1-252 (252) Show / Hide 
Range on Protein: 210-462
Range on HMM: 1-252/252
Sequence Identity: 55% (142 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGAMSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYL-HEHGRGLTVQQLVD
 |...|.| |..|||||| ||  |.|||||||...||  .|| || .|||.|| ...|.|||| | ||.||. |||. |.|.||| ..... . . .|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLENDDIYEAHQGAKFPIKWTAPEAANYNRFSTKSDVWAFGILMMEIITLGRVPYP
| |.||||| ||. .|.|||||||||||||. ||||. |||. | . ..|.| ..||||.|||||||||| | ||  |||||.||||| |..| ||.|||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLAR-MMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMSNAEVLRRVDVPEKYRMPKPQNCPDEYHAI-MFACWQHEADDRPLFESLKVQL
|| | ||| .||  . |||||...|||  . . |. ||  ..  || || |   .
GMMNREVLDQVD--RGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase Src3.AA SRM 212-463 51 4.2e-118 396.73 In-house 3-253 (253) Show / Hide 
Range on Protein: 212-463
Range on HMM: 3-253/253
Sequence Identity: 51% (132 aa)

LERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGA-MSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYLHE-HGRGLTVQQLVDM
| ||||.| ||||| | |  .  ||.|  |    |   .. .|   ||||||  .| |.|||. |.| ||| |||| |.|. || .  .. | . .|.|.
LCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLDF

TAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLENDDIYEAHQGAKFPIKWTAPEAANYNRFSTKSDVWAFGILMMEIITLGRVPYPG
  |.| ||.||| ||..|||||||||||||||.|||||||. | |  ||||    . . |.||||||||||  .|.||||| ||||. |. | | .||||
ACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLAR-LIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPG

MSNAEVLRRVDVPEKYRMPKPQNCPDEYHAIMFACWQHEADDRPLFESLKVQLE
|.| | . ..|    |||| |  || | |  |  ||. . ..|| |  |  .| 
MTNHETFQQID--RGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase Src3.AA Tec 210-464 45 6.6e-117 394.68 In-house 1-254 (254) Show / Hide 
Range on Protein: 210-464
Range on HMM: 1-254/254
Sequence Identity: 45% (117 aa)

IRLERKLGAGQFGEVWKGRWNNSTDVAVKTLKPGAMSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYGSLLDYLHEHGRGLTVQQ--LV
. . . || |||| |  |.| .. |||.|..| |.|| ..|. || .|.|| | .|.||| ||.   |.||. | |  |.||.|| ||. ..  ..  | 
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

DMTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLENDDIYEAHQGAKFPIKWTAPEAANYNRFSTKSDVWAFGILMMEIITLGRVPY
.|. ..  |||||| ..|.|||||||| ||||..| || ||||.|    || |    |.|||.|| .||  .|.|.| ||||||||.|| |. ..|..||
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVL-DDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPY

PGMSNAEVLRRVDVPEKYRMPKPQNCPDEYHAIMFACWQHEADDRPLFESLKVQLED
. ||| ||  .|     .|. .|. |...   ||  ||......|| |. |  |...
ENMSNSEVVEHVSQG--HRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase Src3.AA S_TKc 210-466 22 3.4e-53 183.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 210-466
Range on HMM: 1-231/231
Sequence Identity: 22% (62 aa)

IRLERKLGAGQFGEVWKGRWNN-STDVAVKTLKPGAMSSDEFLSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRY--GSLLDYLHEHGRG-----L
 .. ||.| | ||.|.|.|...    ||.| .|      . ...| .|.|| .| |...|| |. | . .|.. |..    |.|.||....||.     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TVQQLVDMTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVCKVGDFGMSRGLENDDIYEAHQGAKFPIKWTAPEAANYNRFST-KSDVWAFGILMMEII
.  .   ...||.....|.  ....||||   |.|. .  . |..|||..| |                 . |||      ... |.|.|..|... | .
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TLGRVPYPGMSNAEVLRRVDVPEKYRMPKPQNCPDEYHAIMFACWQHEADDRPLFESLKV-----QLEDFA
. |. |.|    .......              ..|   ..  |.| . ..||    .        .  . 
C-GYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Src3.AA Pkinase 210-462 22 1.9e-45 161.79 Pfam 1-293 (293) Show / Hide 
Range on Protein: 210-462
Range on HMM: 1-293/293
Sequence Identity: 22% (67 aa)

IRLERKLGAGQFGEVWKGRWNNSTD-VAVKTLKPGAMSSDEF-----LSEAAIMKKLRHTNLIQLYAVCTDGEPMYIISELMRYG----SLLDYLH-EHG
....||.|.| ||.|.|... .. . ||||..|    .|..      |||..|||.|.| | ..|| ...|.  .|.. |... |    .| ||.. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RGL--TVQQLVDMTAQIASGMAYLEGQNFVHRDLAARNVLVGDNNVC----KVGDFGMSRGLENDDIYEAHQGAKFPIKWTAPEAAN-YNRFSTKSDVWA
...  . ... ..  ||..|..|.  ....||||   |.|. .|...    |..||| .. ..    ..  ..    . . |||  . ..  ..|.|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGILMMEIITLGRVPYPGM-----SNAEVLRRVDVPEKYRMPKPQNCP-------------------DEYHAIMFACWQHEADDRPLFESLKVQ--L
.|... | .. || |.||       .  .. . . . ... . |. |.                   .|   ..  |..    .|| .| ..    .
CGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF