Gene Src1 (M.brevicollis)

Src1

Species: M.brevicollis
Alias: Src1
External Links:
Annotation:

Classification

Group: TK
Family: SFK-Src

Sequence

Name Sequence Type Origin Length Description Download
Src1.AA Protein None 495 None Fasta, JSON
Src1.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of Src1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3_1 Src1.AA SH3_1 50-97 42 4.9e-23 80.55 Pfam 1-49 (49) Show / Hide 
Range on Protein: 50-97
Range on HMM: 1-49/49
Sequence Identity: 42% (21 aa)

IALYDYEARTADDLTFQKGEKLKITNNSDG-DWWQATSLITGKSGYIPS
.|||||.|...|.|.|.||..... . ||. ||| . .. ||. |..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3 Src1.AA SH3 47-104 36 8.9e-23 82.91 SMART 1-58 (58) Show / Hide 
Range on Protein: 47-104
Range on HMM: 1-58/58
Sequence Identity: 36% (21 aa)

NLFIALYDYEARTADDLTFQKGEKLKITNNSDGDWWQATSLITGKSGYIPSNFVAAVQ
  ..|||||.|...|.|.|.||... ... .|..||...   ||. |..|||.|. ..
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 Src1.AA SH3_2 48-103 20 2e-12 46.37 Pfam 1-68 (68) Show / Hide 
Range on Protein: 48-103
Range on HMM: 1-68/68
Sequence Identity: 20% (14 aa)

LFIALYDYEA-RTADD-----LTFQKGEKLKIT---NNSDGDWWQA-TSLITGKS--GYIPSNFVAAV
..... ||.. . ...     |.|.||...|..   . ....||.. ... .|.   |..||..|. .
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 Src1.AA SH2 111-187 56 1.8e-48 144.17 Pfam 1-81 (81) Show / Hide 
Range on Protein: 111-187
Range on HMM: 1-81/81
Sequence Identity: 56% (46 aa)

WYHGRIKRAEAEKVLML-TGVEGSFLIRESESKPGQYALSIRTGD---IVKHYSIRTLDEGGYYITSRVTFRTLQELVSHY
|||| | |.|||. ||  .. .|.||.|||||.||.|.|| |...    |||| |...|.|||||| |..|..|||||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 Src1.AA SH2 109-193 48 1.6e-38 135.25 SMART 1-87 (87) Show / Hide 
Range on Protein: 109-193
Range on HMM: 1-87/87
Sequence Identity: 48% (43 aa)

EDWYHGRIKRAEAEKVLMLT-GVEGSFLIRESESKPGQYALSIRTGDIVKHYSIRTLDEGGYYITS--RVTFRTLQELVSHYRESADG
. ||||.| |.|||. |.   . .|.||.|.|||.||.|.||.|... |||| ||..|.|.|||.   |..| .| ||| ||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase Src1.AA SFK-Src 228-482 79 3.4e-253 759.8 In-house 1-259 (259) Show / Hide 
Range on Protein: 228-482
Range on HMM: 1-259/259
Sequence Identity: 79% (206 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGSMSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYLHD-KGRALNLPQLVD
|.|..|||||||||||.|.||.||||||||||||.|||||||.||.|||.||||.||||||||||.|||||.|||||.||||||||. .||.|..|||||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQESE-YTAREGAKFPIKWTAPEAALMNRFSIKSDVWAFGILLTELVTYGRIPY
||||||.||||||||||||||||||||||||||.|||||||.||||.|..| |||.||||||||||||||..|||||||||||.||||..|.||||||||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTNAEVLQQVER--GYRMPAPTNCPPELYNIMLDCWKFKPDERPTFETLQYRLEDFF
|||||.||||||.|  |||||.|.|||.|.|.||.|||...||.|||||.|....||||
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase Src1.AA Src 228-478 70 5.8e-188 630.73 In-house 1-255 (255) Show / Hide 
Range on Protein: 228-478
Range on HMM: 1-255/255
Sequence Identity: 70% (181 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGSMSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYLH--DKGRALNLPQLV
| |. |||.||||.|| |.||..|.|||||||||.|| | ||.|| .|| |||.||.||||||...||||||||.|..|||||||.  ..||.|.||||.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLG-QESEYTAREGAKFPIKWTAPEAALMNRFSIKSDVWAFGILLTELVTYGRIP
|||||||.||||||..|..||||||||||||.|| |||.|||| |..   . ||.||.|||||||||||||.. .||.|||||| |||||||.|||||.|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMTNAEVLQQVERGYRMPAPTNCPPELYN-IMLDCWKFKPDERPTFETLQYRL
||||||.||||||||||||| |.|||.|||. ||| ||. .|..|||||.||  |
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Src1.AA Frk 228-482 69 8.10000000001e-164 550.53 In-house 1-260 (260) Show / Hide 
Range on Protein: 228-482
Range on HMM: 1-260/260
Sequence Identity: 69% (181 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGSMSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYLH---DKGRALNLPQL
|.|  .|||||||.|| | || || |||||||||.|  ..||.|| .||.|||||||||||||| .|||||.||||..|||..||    |||| ....||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDMAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQESE--YTAREGAKFPIKWTAPEAALMNRFSIKSDVWAFGILLTELVTYGR
||||||||.|||||| ||..||||||||||||..| ||. |||| ||| .. |  | .| ||.||||||||||| .|.|.||||||.|||||||..||||
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

IPYPGMTNAEVLQQVERGYRMPAPTNCPPELYNIMLDCWKFKPDERPTFETLQYRLEDFF
.||||||||||||.|..||||| |.|||..||.|||.||. .|..||||||||..|||.|
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase Src1.AA Pkinase_Tyr 228-478 47 4.4e-158 536.0 Pfam 1-270 (270) Show / Hide 
Range on Protein: 228-478
Range on HMM: 1-270/270
Sequence Identity: 47% (128 aa)

IELKSKLGSGQFGDVWRGVWN-----KTTEVAVKTLKPGSMSA----EEFLKEAGVMKRL-RHPKLIQLYAVCT-DKEP--IYIVTELMKNGSLLDYLHD
|..  |||.|.||.|..|.|.     ....||||.||.|.|.     |.|..|| .|| | .||....||.||| ..||  ||||.|.|..|.|||||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K---GRALNLPQLVDMAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQESEY-TAREGAKFPIKWTAPEAALMNRFSIKSDVWAF
.   ...|....|..|..|.|.||.|||..|..||||||||.||..||..|..||||.| .  ...| ..|.|.|.||||.|||.   ..|..|||||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLTELVTYGRIP-YPGMTNAEVLQQV-ERGYRMPAPTNCPPELYNIMLDCWKFKPDERPTFETLQYRL
|.|. |..|||..| ||||.|.||.... |.|||||.| |||.|.|..|..||...|..||||. .. .|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Src1.AA SrcA 228-478 66 1.1e-157 502.2 In-house 1-250 (250) Show / Hide 
Range on Protein: 228-478
Range on HMM: 1-250/250
Sequence Identity: 66% (168 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGSMSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYLHDK-GRALNLPQLVD
|.|. .|| |.||.|| | || || ||.|||||| || | ||.|| .||.||| ||.|||||  . |||||||| |  |||||.| |. |..| ||||||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSE-EPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

MAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQESEYTAREGAKFPIKWTAPEAALMNRFSIKSDVWAFGILLTELVTYGRIPYP
||||||.||||.|  |..|||| | |.|||.|  ||. |||| |.. .. ||||| |||||||||||||||  || ||||||.|||||||||| ||.|||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLI-EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTNAEVLQQVERGYRMPAPTNCPPELYNIMLDCWKFKPDERPTFETLQYRL
|| | |||.||||||.|| | .||  |...|  ||.  |.|||||| ||  |
GMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase Src1.AA Src-Unclassified 228-478 51 1e-148 500.38 In-house 1-284 (284) Show / Hide 
Range on Protein: 228-478
Range on HMM: 1-284/284
Sequence Identity: 51% (145 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPG---SMSAEEFL--------KEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYLHDKG
. |. ||| |||| || | |    .|||||..||    || | ||        .|| .|| .||..|..|||||.. ||.||.||.| |||||..|   |
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

-RALNLPQL------------VDMAAQVASGMAYLEAQNFVHRDLAARNVLVGDNN-----TCKVGDFGLSR-VLGQESEYTAREGAKFPIKWTAPEAAL
 . | .. .            ||.|||||||| |||.   |||||||||||.|.||       || |||| |  | |. .| .| ||.||.||.|||...
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

MNRFSIKSDVWAFGILLTELVTYGRIPYPGMTNAEVLQQVERGYRMPAP--TNCPPELYN-IMLDCWKFKPDERPTFETLQYRL
   |||||||| .|||| |. |.|..||||| | ||| .|||||||| |    ||  .|  ||. ||   |. ||||.||   .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase Src1.AA TyrKc 228-478 42 8e-147 494.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 228-478
Range on HMM: 1-280/280
Sequence Identity: 42% (121 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGSMSAEEFLKEAGVMKRL--RHPKLIQLYAVCTDK-------EPIYIVTELMKNGSLLDYLHDKGRA
|.|. |||.|.|| |..|.|.  ..||||.||...   |.|..|| .|..|  .|| ...||.|||..       ||..||.|.|..|.|.|||..... 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LNLPQLVDMAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQE-------SEYTARE--GAK--FPIKWTAPEAALMNRFSIKSDV
|....|.... |.|.||.||. .|..||||||||.|||.|.|.|..|||||| .. .       . |...|  |.|  .||.|.|||.   ..|..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WAFGILLTELVTYGRIPYPG-----MTNAEVLQQVERGYRMPAPTN--------CPPELYNIMLDCWKFKPDERPTFETLQYRL
|.||... |. |||  ||||     |.|.||...|..||||| | |        ||.|.|.||..||...|..||||...  ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Src1.AA SrcB 228-479 62 2.8e-142 478.95 In-house 1-251 (251) Show / Hide 
Range on Protein: 228-479
Range on HMM: 1-251/251
Sequence Identity: 62% (159 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGSMSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYLH-DKGRALNLPQLVD
. |  |||.||||.|| | .|. . |||||.|.|.|| | ||.|| ||| | | .|..|||| | ||||||.|| |..|.|||.|  |.|  |.||.|.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVT-KEPIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQESEYTAREGAKFPIKWTAPEAALMNRFSIKSDVWAFGILLTELVTYGRIPYP
|.||.| ||||.| .|..|||| | |.|| .   ||. |||| |.. .. |||||||||||||||||||     | ||||||.|||||.|.|||||||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARII-EDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTNAEVLQQVERGYRMPAPTNCPPELYNIMLDCWKFKPDERPTFETLQYRLE
||||.||....||||||| | |||.||||||  ||| .|.|||||. ||  |.
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase Src1.AA Src-Echino1 228-478 59 6.2e-134 451.24 In-house 1-252 (252) Show / Hide 
Range on Protein: 228-478
Range on HMM: 1-252/252
Sequence Identity: 59% (150 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGSMSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYL-HDKGRALNLPQLVD
 ... |.|.|..|.||.||||  |.|||||||...||  .|| || |||..||  ..|.|||| ||||||||||||.||.|.||| ..|.. . ...|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQESEYTAREGAKFPIKWTAPEAALMNRFSIKSDVWAFGILLTELVTYGRIPYP
| |..|||| ||. .|.|||||||||||||. | ||. |||| |.. |. .| ...|||.|||||||||||  || ||||||.||||.||.||.||.|||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMM-QKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTNAEVLQQVERGYRMPAPTNCPPELYNI-MLDCWKFKPDERPTFETLQYRL
||.| |||.||.|||||| . .||  ||.. |. ||   |  ||||| |   .
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase Src1.AA TK 228-478 26 4.4e-133 448.41 In-house 1-486 (486) Show / Hide 
Range on Protein: 228-478
Range on HMM: 1-486/486
Sequence Identity: 26% (130 aa)

IELKSKLGSGQFG---DVWRGVW--------------------------NKTTEVAVKTLKPG-SMSAEE--------------FLKEAGVMKRLR----
|.|  |||.||||   .|..| |                          ...|.||||.||.| .||.||              ||.|| .|| ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPKLIQLYAVCTDK------------EPIYIVTELMKNGS----LLDYLHDKGRA--------------------------------------------
 || ...||.|||..            ||..||.|.|..|.    |.|||... .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNLPQLVDMAAQVASGMAYLEAQ------NFVHRDLAARNVLVGDNNT-----------CKVGDFG---
                               |...||. |..|.|.||.||...      |||||||||||.|||.||.           ||..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRVLGQESEYTARE------------------------GAKFPIKWTAPEAAL---------MNRFSIKSDVWAFGILLTELVTYGRIPYPG-M
     |.| ......|....                        |.|.||.|.|||. .          ..|..|||||.||.|. |..|||. ||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------AEVLQQVERG--------------YRMPAPTNCP--------------PELYNIMLDCWKFKPDERPTFETLQYRL
.|         .||.....||              .|||.| .||              .|.| .|..||...|..||||..|. .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Src1.AA SRM 230-479 53 5.9e-129 433.57 In-house 3-253 (253) Show / Hide 
Range on Protein: 230-479
Range on HMM: 3-253/253
Sequence Identity: 53% (136 aa)

LKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGS-MSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYLHD-KGRALNLPQLVDM
|  |||.| || || | |    .||.|  |    |  ... ||   || ||| ..| |.|||.  .|.||.||||. |.|. || |  ..|| .|.|.|.
LCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLDF

AAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQESEYTAREGAKFPIKWTAPEAALMNRFSIKSDVWAFGILLTELVTYGRIPYPG
| ||| ||.||| ||..|||||||||||||||.|||||||| | .  .  |    . . |.||||||||    .|.||||| ||||| |. ||| .||||
ACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLI-KDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPG

MTNAEVLQQVERGYRMPAPTNCPPELYNIMLDCWKFKPDERPTFETLQYRLE
||| | .||..|||||| |  |||| .  ||.||.  |..||.| .|  .| 
MTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase Src1.AA Tec 228-480 48 1.2e-119 403.84 In-house 1-254 (254) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-254/254
Sequence Identity: 48% (124 aa)

IELKSKLGSGQFGDVWRGVWNKTTEVAVKTLKPGSMSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNGSLLDYLHDKGRALNLPQ--LV
. .   ||||||| | .| |    .||.|..| |||| |.|. || ||. | ||||.||| ||. . ||||||| |..|.||.||  ..  .   .  | 
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

DMAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSR-VLGQESEYTAREGAKFPIKWTAPEAALMNRFSIKSDVWAFGILLTELVTYGRIP
.|  .|  |||||| ..|.|||||||| ||||..  || |||..| ||    .||   |.|||.|| .||    .|.| ||||||||.|  |  . |..|
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVL--DDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMP

YPGMTNAEVLQQVERGYRMPAPTNCPPELYNIMLDCWKFKPDERPTFETLQYRLED
|. |.| || ..| .|.|.  |  |. ..| || .||. ||.|||||. |   ...
YENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase Src1.AA S_TKc 228-482 24 6.7e-60 206.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 228-482
Range on HMM: 1-231/231
Sequence Identity: 24% (65 aa)

IELKSKLGSGQFGDVWRGVWNK-TTEVAVKTLKPGSMSAEEFLKEAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKN--GSLLDYLHDKGRA-----L
 |.  |.|.| || |......|   .||.| .|      | ...|  ..|. .|| ...|| |. | . .|.|.|.. .  |.|.||....||      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NLPQLVDMAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTCKVGDFGLSRVLGQESEYTAREGAKFPIKWTAPEAALMNRFSI-KSDVWAFGILLTELV
.  .   ...|......|.  ....||||   |.|. .  . |..||||.|.|                 . |||      ..  |.|.|..|..| |..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TYGRIPYPGMTNAEVLQQVERGYRMPAPTNCPPELYNIMLDCWKFKPDERPTFETLQY-----RLEDFF
. |. |.|  . .......            .||. ...  |... |..|||   .       ..  .|
C-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Src1.AA Pkinase 228-472 25 8e-53 186.6 Pfam 1-285 (293) Show / Hide 
Range on Protein: 228-472
Range on HMM: 1-285/293
Sequence Identity: 25% (75 aa)

IELKSKLGSGQFGDVWRGVWNKTTE-VAVKTLKPGSMSAEE---FLK--EAGVMKRLRHPKLIQLYAVCTDKEPIYIVTELMKNG----SLLDYLH-DKG
.....|.||| || |..... .| . ||||..|  . . ..    ..  |. .||||.||  ..|| ...||  ||.|.|.. .|    .| ||.. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RAL--NLPQLVDMAAQVASGMAYLEAQNFVHRDLAARNVLVGDNNTC----KVGDFGLSRV--LGQESEYTAREGAKFPIKWTAPEAAL-MNRFSIKSDV
...     .. ... |...|..|. .....||||   |.|. .|...    |..||||...  .   | .| . |  .   . |||  .  .  . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW---YMAPEVIRGGQYYGPKVDM

WAFGILLTELVTYGRIPYPGM----TNAEVLQQVERGYRMPAPTNCP-----------------------PELYNIMLDCWKFKPDERPTFE
|..|..| |... || |.||     . .. .| ..|  . | . ..|                       .|.  .. .|....| .|||.|
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE