Gene RTKD1 (M.brevicollis)

RTKD1

Species: M.brevicollis
Alias: RTKD1
External Links:
Annotation:

Classification

Group: TK
Family: RTKD

Sequence

Name Sequence Type Origin Length Description Download
RTKD1.AA Protein None 1547 None Fasta, JSON
RTKD1.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of RTKD1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
EGF RTKD1.AA EGF 32-62 27 0.000124 18.55 Pfam 1-36 (36) Show / Hide 
Range on Protein: 32-62
Range on HMM: 1-36/36
Sequence Identity: 27% (10 aa)

CRVD--SCTNGGACVVHGNFTECVCPSA---WQGLR
|  .   | ..| ||  ..  .| ||     ..| |
CNPNNNPCHHHGTCVDTPGGYTCQCPPGYLGYTGKR
EGF_2 RTKD1.AA EGF_2 32-63 27 0.000374 16.48 Pfam 1-29 (29) Show / Hide 
Range on Protein: 32-63
Range on HMM: 1-29/29
Sequence Identity: 27% (10 aa)

CRVDSCTN-GGACVVHGNFTE---CVCPSA-WQGLRC
|    |.. .| |.      .   |.|..  |||  |
C----CNGHHGTCNNQ----GCGKCQCDDGWWQGDHC
EGF RTKD1.AA EGF 31-64 27 0.001926 18.68 SMART 1-32 (32) Show / Hide 
Range on Protein: 31-64
Range on HMM: 1-32/32
Sequence Identity: 27% (11 aa)

DCRVDSCTNG-----GACVVHGNFTECVCP-SAWQGLRCQ
.|    | .|     | |.      .| ||   ..| ||.
ECA--PCHHGGCEQHGTCI----SYTC-CPGPGYTG-RCE
EGF RTKD1.AA EGF 68-97 27 0.118332 7.88 SMART 1-32 (32) Show / Hide 
Range on Protein: 68-97
Range on HMM: 1-32/32
Sequence Identity: 27% (10 aa)

VCRTNFDCARG------LCQNGKCSCP-GNWGGGACE
 |    .|  |       |.  .| ||   . |  ||
ECA---PCHHGGCEQHGTCISYTC-CPGPGYTG-RCE
EGF_2 RTKD1.AA EGF_2 69-96 32 2.92741 4.3 Pfam 1-29 (29) Show / Hide 
Range on Protein: 69-96
Range on HMM: 1-29/29
Sequence Identity: 32% (11 aa)

CRTNFDCA--RGLCQ---NGKCSCPGN-WGGGAC
|     |   .| |     |||.|. . | |  |
C-----CNGHHGTCNNQGCGKCQCDDGWWQGDHC
EGF RTKD1.AA EGF 75-97 26 7.413134 2.59 Pfam 1-24 (36) Show / Hide 
Range on Protein: 75-97
Range on HMM: 1-24/36
Sequence Identity: 26% (7 aa)

CARG--LCQN-GKCSCPGNWGGGACE
|.     |.. |.|  ..  ||  |.
CNPNNNPCHHHGTCVDTP--GGYTCQ
EGF RTKD1.AA EGF 191-199 50 1.398506 5.01 Pfam 25-36 (36) Show / Hide 
Range on Protein: 191-199
Range on HMM: 25-36/36
Sequence Identity: 50% (6 aa)

CPPG---WTGDY
||||   .||..
CPPGYLGYTGKR
NCD3G RTKD1.AA NCD3G 201-227 37 0.001513 12.5 Pfam 28-54 (54) Show / Hide 
Range on Protein: 201-227
Range on HMM: 28-54/54
Sequence Identity: 37% (10 aa)

CEKCPSGTYKNETSRAPCTTVPTGYYA
|..|| |.| |.|    ||. | ....
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKD1.AA NCD3G 286-311 35 0.000223 14.97 Pfam 28-54 (54) Show / Hide 
Range on Protein: 286-311
Range on HMM: 28-54/54
Sequence Identity: 35% (10 aa)

CRPCPENHINN--GQFAACIPCPAGTFA
| ||||... |  . .  |.||| .  .
CIPCPEGEYSNTTDSY-TCTPCPEDQWP
HYR RTKD1.AA HYR 648-708 34 0.000239 16.34 Pfam 23-86 (86) Show / Hide 
Range on Protein: 648-708
Range on HMM: 23-86/86
Sequence Identity: 34% (23 aa)

DSQVAVNWTVPSVLDNVG---VTAFYASATPGLVKSWN-DLPLTVTYDANDAAGNHE-SCTMVIDV
.| |.| || | . || |   ..    .| ||   ..  .   |||| . |.|||   .||  . |
TSTVNVFWTEPTATDNSGDIQANLISRTAQPGDFFPVGEQ--TTVTYTFQDNAGNQADTCTFTVTV
HYR RTKD1.AA HYR 921-951 28 0.527181 5.33 Pfam 1-32 (86) Show / Hide 
Range on Protein: 921-951
Range on HMM: 1-32/86
Sequence Identity: 28% (9 aa)

EDSEPPQL-TCPLDMERTLGEDESSYILSYAE
 | .||.  .||   .||  .. |.   .. |
VDTTPPTVENCPNNIFRTVELGTSTVNVFWTE
Kinase RTKD1.AA RTKD 1015-1273 64 1.1e-213 716.24 In-house 1-262 (262) Show / Hide 
Range on Protein: 1015-1273
Range on HMM: 1-262/262
Sequence Identity: 64% (168 aa)

LKVLETLGSGHWGIVSKALLEENIMSGVPGFLVAVKILKTQSDEALIELTREAAFMAQFNHDNVVRLHGVITKDQPVIMIMEYCEHGSLQSFLRDN--DT
.|.||..|.|.||.|.||.|||.||.|.|||||||||.|.||.|...|.||||||||||||||.||||||.|..||.||.||||||||||..||.|  |.
IKCLEPIGKGNWGMVFKAMLEEHIMKGIPGFLVAVKIMKNQSQEQVMEMTREAAFMAQFNHDNIVRLHGVVTTNQPHIMVMEYCEHGSLQAYLRENGEDM

APQQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRGKIADLGLTR-QAEADSEYYTSKGGAVPVRWSAPEALEEHKFSQASDVWSWGILLYEIE
..|.|..||.|.|||||||..||..|||.||||.||.|..|.||.|.|||| ||..|||||.|.|.|.||||.|||.|||||||||||||||....|||.
DNQHRFRMARDVAMGLAYLHFRGCCHRDIAARNILLDSNYRAKIGDFGLTRQQANGDSEYYISHGQAIPVRWCAPEVLEEHKFSQASDVWSWAVFVYEIW

TKAALPYDGMSNQKVWINVAAGYRLEKPTQTPAALYALMRDCWAEETRSRPGFCEVVNRLED
|.|.|||..|.|||||..|..||||..|.|.|....|||.|||||....||..|.||.....
TQAQLPYRDMHNQKVWHYVIQGYRLTRPMQCPRDIWALMMDCWAEDPKERPRMCQVVDQMTK
Kinase RTKD1.AA RTKC 1015-1271 50 2.7e-125 415.54 In-house 1-261 (261) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-261/261
Sequence Identity: 50% (133 aa)

LKVLETLGSGHWGIVSKALLEENIMSG-VPGFLVAVKIL-KTQSDEALIELTREAAFMAQFNHDNVVRLHGVITKDQPVIMIMEYCEHGSLQSFLRDN-D
|..|. || |  ||| ||||||   .|  ||.|||.| | .| .| .  ||  ||| ||||.| |||.| ||.|.  |.  ..|.|| ||| |.|  | |
LTLLDELGRGAFGIVYKALLEE---PGGMPGYLVACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYLMNNPD

TAPQQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRGKIADLGLTRQA----EADSEYYTSKGGAVPVRWSAPEALEEHKFSQASDVWSWGILL
  . |... ....| |..  .. | .||||||||||||| |. |.|| || | .    ...  || | .| .||||.|||||.. |||..||||. |||.
CTEHQKVRFCYQCASGMEHIHSFGFIHRDVAARNVLLSSDLTCKVADFGLARESPCNDDSHEAYYRSRSGNLPVRWTAPEALDDRKFSEKSDVWAFGILM

YEIETKAALPYDGMSNQKVWINVAAGYRLEKPTQTPAALYALMRDCWAEETRSRPGFCEVVNRL
||| |||..|||| ||| ||. |.|||||..|.......|..| |||..    || | ||| .|
YEIYTKAEMPYDGWSNQRVWVEVCAGYRLPCPEDCHKEVYDMMMDCWMHTPHDRPTFSEVVHWL
Kinase RTKD1.AA TyrKc 1015-1271 33 7.29999999999e-110 372.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-280/280
Sequence Identity: 33% (98 aa)

LKVLETLGSGHWGIVSKALLEENIMSGVPGFLVAVKILKTQSDEALIELTREAAFMAQF--NHDNVVRLHGVITKD-------QPVIMIMEYCEHGSLQS
.. ...||.|. |.| |. .            |||| ||  .   . .. |||  | ..  .|.|.|||.||.|..       .|. ..|||..||.|..
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FLRDND--TAPQQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRGKIADLGLTRQAEAD------SEYYTSK---GGA--VPVRWSAPEALEEH
.||..     ... |......| | .||. ....||| ||||.|...... ||.| ||.|  . |      ..||..|   ||   .|.|| |||.. ..
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KFSQASDVWSWGILLYEIETKAALPYDG-----MSNQKVWINVAAGYRLEKPTQ--------TPAALYALMRDCWAEETRSRPGFCEVVNRL
||. .|||||.|....|| |  . || |     |||| |  .| .|||...|           |...| .|..||.|.  .|| | |.. ..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKD1.AA TK 1015-1271 20 3.5e-107 360.46 In-house 1-486 (486) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-486/486
Sequence Identity: 20% (101 aa)

LKVLETLGSGH---WGIVSKALLEENIMSGVPGF-------------------LVAVKILKTQSDEALIELTR--------------EAAFMAQFN----
......||.|.   .| | |..... . .. ..|                    ||||.||  ....  |                 ||. |....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HDNVVRLHGVITKD------------QPVIMIMEYCEHGS----LQSFLRDND----------------------------------------------
 |.|.|||.||.|..            .|....|||..||.    |...||...                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------TAPQQRLQMALDAAMGLAYLAGR------GVVHRDVAARNVLLSSELR-----------GKIADLG---
                                 ..|.| |....| |..||. .      ..||||.||||.|......            |||| |   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LTRQAEADSEYYTSK------------------------GGAVPVRWSAPEALEEHK---------FSQASDVWSWGILLYEIETKA-ALPYDGM
     |.|  . |..||...                        || .|.|| |||.|....         |. .|||||.|.|..|| | . . .| ||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SNQKVWI-----------------------NVAAGYRLEKPTQTP--------------AALYALMRDCWAEETRSRPGFCEVVNRL
|||.||.                       .|  ..|...| . |              ...| ||..||... . || | .....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKD1.AA Pkinase_Tyr 1015-1271 36 1.2e-106 361.8 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-270/270
Sequence Identity: 36% (98 aa)

LKVLETLGSGHWGIVSKALLEENIMSGVPGFLVAVKILKTQSDEA---LIELTREAAFMAQF-NHDNVVRLHGVIT-KDQP--VIMIMEYCEHGSLQSFL
.. ...||.|. | | |. .      . ..  ||||.|| ....    . .. |||. | |. .|.|.|||.||.| ...|  ....|||..||.| ..|
ITFGKKLGEGAFGEVYKGTWKG--DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RDN-----DTAPQQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRGKIADLGLTRQAEADSEY-YTSKGGAVPVRWSAPEALEEHKFSQASDVW
|..        ... |||... |.|..||. .. .|||.||||.|.....  ||.| ||.|  . |..| ....|| .|..| |||.. . ||. .||||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SWGILLYEIETKAALP-YDGMSNQKVWINV-AAGYRLEKPTQTPAALYALMRDCWAEETRSRPGFCEVVNRL
| |.|..|| |  . | | ||||. |   .   |||...|  .|. .| ||..||...   || | |....|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKD1.AA UTK 1015-1271 36 6.9e-102 344.8 In-house 1-296 (296) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-296/296
Sequence Identity: 36% (110 aa)

LKVLETLGSGHWGIVSKALLEE--NIMSGVPGFLVAVKILK-----TQSDE---ALIELTREAAFMAQFN-HDNVVRLHGVITKDQPVIMIMEYCEHGSL
.. ...||.|. |.|.|| ...  ..|  .   .|||| ..     .|. |    ..|..||...|.||. | ||.|| || |...| ....||.| |.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEM---DVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDL

QSFLRDNDTAPQ---------QRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSE-------LRGKIADLG---LTRQAEA--------DSEYYTSKG
.|.||..  .|          |||.||.| | |..||...|.||||.||||.|. .        .  ||||.|   ..|.. .        .|.||.. .
RSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH

-GAVPVRWSAPEALEEH-KFSQASDVWSWGILLYEIETKAALPYDGMSNQKVWINVAAG--YRLEKPTQTPAALYALMRDCWAEETRSRPGFCEVVNRL
 ...|.|| ||||| .| .|...|||||.|....|| | ..||| ||||..|| .| .|  ||...| . |...| ||..||. . . || | ..| ..
QDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKD1.AA Eph 1015-1271 41 7.9e-83 278.07 In-house 1-264 (264) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-264/264
Sequence Identity: 41% (109 aa)

LKVLETLGSGHWGIVSKALLEEN-IMSGVPGFLVAVKILK-TQSDEALIELTREAAFMAQFNHDNVVRLHGVITKDQPVIMIMEYCEHGSLQSFLRDNDT
.|. . .|.|  | | .  |  .     |   .||.| || . .. . ..  .||. | ||.| |..|| ||.|| .||  . || |.||| |||| .| 
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

--APQQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRGKIADLGLTRQAEADS---EYYTSKGGAVPVRWSAPEALEEHKFSQASDVWSWGILL
   . | . |    | |  ||.  . |||| ||||.|..|.|. |..|.||.|. | |.     ||..|| .|.|| ||||.   ||. ||||||.||..
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVM

YEIETKAALPYDGMSNQKVWINVAAGYRLEKPTQTPAALYALMRDCWAEETRSRPGFCEVVNRL
 |. .    ||  ||||.|   .  ||||  |   |.||. || |||. .  .|| | ..|. |
WEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase RTKD1.AA SFK-Src 1047-1275 40 1.6e-78 232.2 In-house 26-259 (259) Show / Hide 
Range on Protein: 1047-1275
Range on HMM: 26-259/259
Sequence Identity: 40% (94 aa)

VAVKILKTQSDEALIELTREAAFMAQFNHDNVVRLHGVITKDQPVIMIMEYCEHGSLQSFLRD---NDTAPQQRLQMALDAAMGLAYLAGRGVVHRDVAA
|||| ||  .  |  |  .||. | .  |.| ..|. | |   |.  | | .  |||  .|..        .|   || . | |.||| .   |||| ||
VAVKTLKPGAMSA-EEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVDMAAQVAHGMAYLEAQNFVHRDLAA

RNVLLSSELRGKIADLGLTRQAEADSEYYTSKGGA-VPVRWSAPEALEEHKFSQASDVWSWGILLYEIETKAALPYDGMSNQKVWINVAA--GYRLEKPT
||||       |..| |. |  ..|.| || . ||  |..| ||||    .||  ||||| |||..|| |    ||.||.|. |   |    |||...|.
RNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPP

QTPAALYALMRDCWAEETRSRPGFCEVVNRLEDFA
 .| ..|..|.||| .|   || |     ..||| 
NCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase RTKD1.AA Fer 1015-1272 31 1.6e-76 260.11 In-house 1-283 (283) Show / Hide 
Range on Protein: 1015-1272
Range on HMM: 1-283/283
Sequence Identity: 31% (89 aa)

LKVLETLGSGHWGIVSKA---LLEENIMSGV-PGFLVAVKILKTQ-SDEA-LIELTREAAFMAQ-FNHDNVVRLHGVITKDQPVIMIMEYCEHGSLQSFL
 .  . ||.|. |.| |.   | . . .. | .   |.|| .|.  .... ..|. .|| .| . ..|.|||...||.. .||.  .||.| .|||.|.|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RDND--TAPQ-QRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSS-ELRGK--IADLGLTRQAEADSEYYTSK--GGAVPVRWSAPEALEEHKFSQASD
. |.  | .  ....|...|| |..|| .....|||.||||.|..  ..  |  |.| |. || . . . |. |     ||.|| |||...   .| ..|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSWGILLYEIETKAALPYDG----MSNQKV-----WINVAAGYRLEKPTQTPAALYALMR-DCWAEETRSRPGFCEVVNRLE
|||.|....|| |..| || |    | .  |        . .||..  | ..| ... .|  .||....  || . |....|.
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase RTKD1.AA Src 1015-1271 36 2.6e-76 258.74 In-house 1-255 (255) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-255/255
Sequence Identity: 36% (96 aa)

LKVLETLGSGHWGIVSKALLEENIMSGVPGFLVAVKILKTQSDEALIELTREAAFMAQFNHDNVVRLHGVITKDQPVIMIMEYCEHGSLQSFLR-DNDTA
.| .. ||.|. | | ...   |.        |||| ||  .  .   . .||  | .. |...|.|. | ... |.  . || .||||. .|. | .. 
IKLCRKLGQGQFGEVWMGYWNGNTK-------VAVKTLKPGT-MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGR

---PQQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRGKIADLGLTRQAE-ADSEYYTSKGGAVPVRWSAPEALEEHKFSQASDVWSWGILLYE
    .| . ||   | | |||  . ..||| |||||| . ..  |.|| || |  .  | ||  ..|  .|..| ||||. ...|.. ||||| ||||.|
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTE

IETKAALPYDGMSNQKVWINVAAGYRLEKPTQTPAALYA-LMRDCWAEETRSRPGFCEVVNRL
| |.   || ||.|. |  .| .|||. .|.. |. ||  .|. || .. . || |    . |
IVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase RTKD1.AA CTKA 1015-1271 35 3.6e-73 245.19 In-house 1-290 (290) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-290/290
Sequence Identity: 35% (104 aa)

LKVLETLGSGHWGIVSKALLEENIMSGVP--------GFLVAVKILKTQSDEALI-ELTREAAFMA--QFNHDNVVRLHGVITKDQPVIMIMEYCEHGSL
. .   .|.||.| | .|.|    |   .        | .|||| ||    |.   .   ||   .  .| | ||.|| ||.|...|  ||||.   | |
HCIMFKIGEGHYGQVFRAWL----MPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDL

QSFLRDNDTAP-----------------------QQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRGKIADLGLTRQAEAD-SEYYTSKGGAV
...||    |.                            || ..| |  ||| .| |||| |.||.|| .    ||||.|. |  .     || |. .  
HCYLRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVM

PVRWSAPEALEEHKFSQASDVWSWGILLYEIETKAALPYDGMSNQKVWINVAAG--YRLEKPTQTPAALYALMRDCWAEETRSRPGFCEVVNRL
|||| ||||| . ||| |||||. |.||.|| . . .|. .|| | |   ....   ||  |   |  || .|  ||  |   || |  .   |
PVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase RTKD1.AA TK-Unique 1015-1271 31 1.1e-70 241.11 In-house 1-294 (294) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-294/294
Sequence Identity: 31% (94 aa)

LKVLETLGSGHWGIVSKALLEENIMSGVPGFLVAVKILK-TQSDEALIELTREAAFMAQFN-HDNVVRLHGVITKDQ-PVIMIMEYCEHGSLQSFLRDND
|.|....|.|  | | .. .......      |||| ||   .|.   ....|...| .   | |.|.. |. ||.. |. .|||||. |.||..|| . 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

TAPQQR---------------------LQ------MALDAAMGLAYLAG--RGVVHRDVAARNVLLSSELRGKIADLGLTRQAEADSEYYTSKG-GAVPV
 |. |                      ..       | . |.|..|||.  ...||||..||||||.. .. ||.|.|..|  ... .| .... | .|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWSAPEALE--EHKF-SQASDVWSWGILLYEIETKAALPYDGMSNQKVWINVAAGYRLEKPTQT-PAALYALMRDCWAEETRSRPGFCEVVNRL
|| |||.|   .. . .  ||||| |.|..|| |  | || ||.. ..  .. .|||...| .  . ..| ||. || .|  .|| | ....||
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKD1.AA S_TKc 1015-1275 21 3.1e-41 144.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 1015-1275
Range on HMM: 1-231/231
Sequence Identity: 21% (59 aa)

LKVLETLGSGHWGIVSKALLEENIMSGVPGFLVAVKILKTQSDEALIELTREAAFMAQFNHDNVVRLHGVITKDQPVIMIMEYCEH--GSLQSFLRDND-
 ..|...|.|  | | |.   .       | .||.||.|       . . || . . . .|.|.|.|..|.   . . |.||||..  |.| ......  
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------TAPQQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRGKIADLGLTRQAEADSEYYTSKGGAVPVRWSAPEALEEHKFSQ-ASDVWSWG
        . .   ..   . .|.|.  .|..|||.   |.||..  . ||.| || ||          .   .   . ||| |   ...  ..|.|| |
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

ILLYEIETKAALPYDGMSNQKVWINVAAGYRLEKPTQTPAALYALMRDCWAEETRSRPGFCEVVN-----RLEDFA
..|||  .    |..   .... ...            .  .  ..| |.  . . ||.  |. .     ..  . 
CILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKD1.AA Pkinase 1015-1271 20 4.6e-34 121.51 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1015-1271
Range on HMM: 1-293/293
Sequence Identity: 20% (63 aa)

LKVLETLGSGHWGIVSKALLEENIMSGVPGFLVAVKILKTQSDEA--LIELTR--EAAFMAQFNHDNVVRLHGVITKDQPVIMIMEYCEHG----SLQSF
.......|||  | | |.    .        .|||||.| ....   .....|  |.. |. .||.|.|||... . .. . |.|||||.|    .| ..
YHIGRKIGSGSFGCVYKCHHKGTGK------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LR---DNDT--APQQRLQMALDAAMGLAYLAGRGVVHRDVAARNVLLSSELRG----KIADLGLTRQAEADSEYYTSKGGAVPVRWSAPEALE-EHKFSQ
..   ..     ...   ...  . ||.|.  .|..|||.   |.|....       ||.| || .|..    .   .. ..  .. ||| .    . ..
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

ASDVWSWGILLYEIETKAALPYDGM-----SNQKVWINVAAGYRLEKPTQTP---------------------AALYALMRDCWAEETRSRPGFCEVVNR
..|.|| |..|||  ..  .|..|       .|.. |.   | .|. . ...                      ..  ....|..    .||.. .... 
KVDMWSCGCILYEMLCGR-PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

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PWF