Gene RTKC4 (M.brevicollis)

RTKC4

Species: M.brevicollis
Alias: RTKC4
External Links:
Annotation:

Classification

Group: TK
Family: RTKC

Sequence

Name Sequence Type Origin Length Description Download
RTKC4.AA Protein None 3303 None Fasta, JSON
RTKC4.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of RTKC4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
GCC2_GCC3 RTKC4.AA GCC2_GCC3 45-92 38 0.201594 7.59 Pfam 1-49 (49) Show / Hide 
Range on Protein: 45-92
Range on HMM: 1-49/49
Sequence Identity: 38% (19 aa)

GYVG-KEQGKCTDLCPIGTFGIDDCNGGCRSCSPG-TYTSVPGSTYCQTC
|.   |.|..|. .||.||.   . .. | .|.|| |.|. ||||. . |
GTYYNKGQNPCE-PCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKC4.AA NCD3G 72-98 25 0.746846 4.5 Pfam 28-54 (54) Show / Hide 
Range on Protein: 72-98
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CRSCSPGTYTSVPGSTYCQTCNWPLYS
|  | .|.| . ..|. |..| .  ..
CIPCPEGEYSNTTDSYTCTPCPEDQWP
TNFR_c6 RTKC4.AA TNFR_c6 75-92 40 4.052713 3.84 Pfam 1-19 (41) Show / Hide 
Range on Protein: 75-92
Range on HMM: 1-19/41
Sequence Identity: 40% (8 aa)

CSPG-TYTSVPGS-TYCQTC
|.|| |||. ..    |. |
CPPGKTYTD-WNHVPHCLSC
GCC2_GCC3 RTKC4.AA GCC2_GCC3 202-219 44 0.000175 17.55 Pfam 1-18 (49) Show / Hide 
Range on Protein: 202-219
Range on HMM: 1-18/49
Sequence Identity: 44% (8 aa)

GYFSSAGATSCTPCPKGT
|.....|   |.|||.||
GTYYNKGQNPCEPCPRGT
NCD3G RTKC4.AA NCD3G 181-205 22 0.00048 13.98 Pfam 28-54 (54) Show / Hide 
Range on Protein: 181-205
Range on HMM: 28-54/54
Sequence Identity: 22% (6 aa)

CQECQAGSYTH--NNINCINCQSGYFS
|  | .|.| .  . ..|. |  .. .
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKC4.AA NCD3G 117-143 32 0.00064 13.61 Pfam 27-54 (54) Show / Hide 
Range on Protein: 117-143
Range on HMM: 27-54/54
Sequence Identity: 32% (9 aa)

TCYKCPETHIVN-SDRGGCSPCGPGTYA
.| .||| ...| .|   | || .. ..
DCIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKC4.AA GCC2_GCC3 224-243 55 0.000975 15.12 Pfam 9-28 (49) Show / Hide 
Range on Protein: 224-243
Range on HMM: 9-28/49
Sequence Identity: 55% (11 aa)

NNCVPCPLGEYQSAVGQSWC
|.|.||| | ||. .||  |
NPCEPCPRGTYQNEEGQDSC
NCD3G RTKC4.AA NCD3G 148-174 32 0.00191 12.2 Pfam 28-54 (54) Show / Hide 
Range on Protein: 148-174
Range on HMM: 28-54/54
Sequence Identity: 32% (9 aa)

CINCNPGSISNLTANA-KCLACTGGKIS
|| | .|..|| | ..  |. |. .  .
CIPCPEGEYSNTT-DSYTCTPCPEDQWP
FU RTKC4.AA FU 162-235 18 0.061318 5.41 SMART 1-48 (48) Show / Hide 
Range on Protein: 162-235
Range on HMM: 1-48/48
Sequence Identity: 18% (14 aa)

NAKCLACTGGKISSPDGASCQE-CQAGSYTHNNINCINCQSGYFSSAGATSCTPCPKGTKGVGNNCVP-CPLGEYQ
. .| .|          ..| . |        . .|. | .||.                   . ||. || |.| 
DGVCKPCH---------PECATGCWGPG----PDQCTSCPHGYYLHHN---------------GTCVSQCPPGYYP
NCD3G RTKC4.AA NCD3G 212-236 32 0.547734 4.9 Pfam 28-54 (54) Show / Hide 
Range on Protein: 212-236
Range on HMM: 28-54/54
Sequence Identity: 32% (9 aa)

CTPCPKGTKGV--GN-NCVPCPLGEYQS
|.||| |.     .  .|.|||.. . .
CIPCPEGEYSNTTDSYTCTPCPED-QWP
TNFR_c6 RTKC4.AA TNFR_c6 199-220 20 0.601761 6.67 Pfam 1-28 (41) Show / Hide 
Range on Protein: 199-220
Range on HMM: 1-28/41
Sequence Identity: 20% (6 aa)

CQSG-YFSSAGAT-S----CTPCPK-GTK
|. | ....  .. .    ||.|.. |..
CPPGKTYTD-WNHVPHCLSCTRCHPMGQY
GCC2_GCC3 RTKC4.AA GCC2_GCC3 171-189 26 3.860031 3.42 Pfam 1-19 (49) Show / Hide 
Range on Protein: 171-189
Range on HMM: 1-19/49
Sequence Identity: 26% (5 aa)

GKISSPDGASCQECQAGSY
|  ..  .. |. |  |.|
GTYYNKGQNPCEPCPRGTY
GCC2_GCC3 RTKC4.AA GCC2_GCC3 125-168 22 6.563713 2.67 Pfam 2-31 (49) Show / Hide 
Range on Protein: 125-168
Range on HMM: 2-31/49
Sequence Identity: 22% (10 aa)

HIVNSDRGGCSPCGPGTYASVSVCINCNPGSISNLTANAKCLAC
.  |.  . |.||. |||               |   . .|..|
TYYNKGQNPCEPCPRGTY--------------QNEEGQDSCIPC
Laminin_EGF RTKC4.AA Laminin_EGF 177-199 20 10.533121 2.05 Pfam 36-59 (59) Show / Hide 
Range on Protein: 177-199
Range on HMM: 36-59/59
Sequence Identity: 20% (5 aa)

DGASCQECQAGSYTHNN-INCINC
.|  | .|. | .  ..  .. .|
TGRHCDRCKPGYWGDPWCDPPQGC
TNFR_c6 RTKC4.AA TNFR_c6 137-165 28 27.455563 1.0 Pfam 1-41 (41) Show / Hide 
Range on Protein: 137-165
Range on HMM: 1-41/41
Sequence Identity: 28% (12 aa)

CGPG-TYASVSV-------CINCNP-GS--IS--NLTANAKC
| || || . .        |  |.| |.  ..  . | |..|
CPPGKTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
GCC2_GCC3 RTKC4.AA GCC2_GCC3 264-285 47 0.001682 14.35 Pfam 14-36 (49) Show / Hide 
Range on Protein: 264-285
Range on HMM: 14-36/49
Sequence Identity: 47% (11 aa)

CPRGTYSTQGSVGSCTACPIG-K
||||||  ... .|| .|| | .
CPRGTYQNEEGQDSCIPCPPGKT
NCD3G RTKC4.AA NCD3G 264-287 37 0.001895 12.21 Pfam 31-54 (54) Show / Hide 
Range on Protein: 264-287
Range on HMM: 31-54/54
Sequence Identity: 37% (9 aa)

CPRGTYSTQGSVGSCTACPIGKAS
|| |.|| .    .|| || .  .
CPEGEYSNTTDSYTCTPCPEDQWP
TNFR RTKC4.AA TNFR 264-299 16 0.222065 0.37 SMART 1-50 (50) Show / Hide 
Range on Protein: 264-299
Range on HMM: 1-50/50
Sequence Identity: 16% (8 aa)

CP--RGTYSTQGSV----GSCTACP-IGKAS--ASLGITYDCNA-----C
|.   |.|.....     . |..|      .  . .. . .|.|     |
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC4.AA TNFR_c6 264-281 42 1.722027 5.11 Pfam 1-19 (41) Show / Hide 
Range on Protein: 264-281
Range on HMM: 1-19/41
Sequence Identity: 42% (8 aa)

CPRG-TYSTQGSVGSCTAC
|| | ||. .. |  |..|
CPPGKTYTDWNHVPHCLSC
GCC2_GCC3 RTKC4.AA GCC2_GCC3 430-468 42 8.2e-09 31.62 Pfam 10-49 (49) Show / Hide 
Range on Protein: 430-468
Range on HMM: 10-49/49
Sequence Identity: 42% (17 aa)

TCQTCAKGYYQDSTGQSECKACPAG-TMRDATGGTSSTQC
.|. | .|.||.. || .|..||.| |  | .| || ..|
PCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKC4.AA NCD3G 555-581 25 1.1e-05 18.84 Pfam 28-54 (54) Show / Hide 
Range on Protein: 555-581
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CLICAAGSYQAQLGQTSCTTCADGTTS
|. |..|.|. . . ..||.| ..  .
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKC4.AA GCC2_GCC3 474-506 39 1.2e-05 21.38 Pfam 1-32 (49) Show / Hide 
Range on Protein: 474-506
Range on HMM: 1-32/49
Sequence Identity: 39% (13 aa)

GTEAPLAGSATCSPCSTGRYQNQTSQATCLSCP
||  .  . ..|.||  | |||. .| .|..||
GTYYNKGQ-NPCEPCPRGTYQNEEGQDSCIPCP
NCD3G RTKC4.AA NCD3G 484-511 42 1.5e-05 18.45 Pfam 27-54 (54) Show / Hide 
Range on Protein: 484-511
Range on HMM: 27-54/54
Sequence Identity: 42% (12 aa)

TCSPCSTGRYQNQTSQATCLSCPEGTYQ
.|.|| .| |.|.|   ||..|||. . 
DCIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKC4.AA NCD3G 337-363 29 2.1e-05 18.03 Pfam 28-54 (54) Show / Hide 
Range on Protein: 337-363
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CRDCPAGTYSTVENAESCRVCAAGYTS
| .||.|.||   .. .|  |  .. .
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKC4.AA GCC2_GCC3 508-545 35 0.001018 15.06 Pfam 1-38 (49) Show / Hide 
Range on Protein: 508-545
Range on HMM: 1-38/49
Sequence Identity: 35% (14 aa)

GTYQNVMGAT-SCRPCNNGQYQDGTVSANCKKCAVG-SYT
||| |  . .  | ||  | ||.   .  |..| .| ..|
GTYYN--KGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTT
GCC2_GCC3 RTKC4.AA GCC2_GCC3 641-667 41 0.001409 14.6 Pfam 1-29 (49) Show / Hide 
Range on Protein: 641-667
Range on HMM: 1-29/49
Sequence Identity: 41% (12 aa)

GHYGYNGQ--CFSCPEGTYSDVIDASSCK
|.|  .||  | .|| ||| . ..  ||.
GTYYNKGQNPCEPCPRGTYQNEEGQDSCI
NCD3G RTKC4.AA NCD3G 378-406 40 0.002686 11.76 Pfam 9-45 (54) Show / Hide 
Range on Protein: 378-406
Range on HMM: 9-45/54
Sequence Identity: 40% (15 aa)

CPPGTLK---TGHL-----CEACEAGKYSSTTNAATC
||||. |   .|       |. |..| ||.||.. ||
CPPGFRKKPQKGQHTCCWDCIPCPEGEYSNTTDSYTC
GCC2_GCC3 RTKC4.AA GCC2_GCC3 337-369 45 0.003614 13.27 Pfam 11-45 (49) Show / Hide 
Range on Protein: 337-369
Range on HMM: 11-45/49
Sequence Identity: 45% (16 aa)

CRDCPAGTYSTVENAESCRVCAAG--YTSVAGSTS
|  || |||   |.  ||  | .|  .|.  ||||
CEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTS
TNFR RTKC4.AA TNFR 392-431 22 0.004016 17.62 SMART 1-50 (50) Show / Hide 
Range on Protein: 392-431
Range on HMM: 1-50/50
Sequence Identity: 22% (11 aa)

CE--AGKYSSTTNA----ATCSAHS-AACSA---GSYETVAPTSSSDRTC
|.  .| |... |.     .| ...   |.    | |..   |. |...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC4.AA TNFR_c6 434-468 25 0.004133 14.06 Pfam 1-41 (41) Show / Hide 
Range on Protein: 434-468
Range on HMM: 1-41/41
Sequence Identity: 25% (11 aa)

CAKG-YYQDSTGQ-SEC---KACPA-GT--MRDATGGTSSTQC
|..| .|.| ... . |   . |.  |.  ... |  |. |.|
CPPGKTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTW-TQNTVC
NCD3G RTKC4.AA NCD3G 602-628 22 0.004766 11.02 Pfam 28-54 (54) Show / Hide 
Range on Protein: 602-628
Range on HMM: 28-54/54
Sequence Identity: 22% (6 aa)

CTACSDASAQPQPGSTACVLCPNGTKA
|. | . . . ...|. |. || .  .
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKC4.AA NCD3G 430-452 34 0.005272 10.89 Pfam 27-49 (54) Show / Hide 
Range on Protein: 430-452
Range on HMM: 27-49/54
Sequence Identity: 34% (8 aa)

TCQTCAKGYYQDSTGQSECKACP
.|  |. | |...|.  .|. ||
DCIPCPEGEYSNTTDSYTCTPCP
NCD3G RTKC4.AA NCD3G 519-546 35 0.006204 10.68 Pfam 28-54 (54) Show / Hide 
Range on Protein: 519-546
Range on HMM: 28-54/54
Sequence Identity: 35% (10 aa)

CRPCNNGQYQDGTVSANCKKCAVGSYTP
| || .|.|.. | | .|..|  . . |
CIPCPEGEYSNTTDSYTCTPCPED-QWP
NCD3G RTKC4.AA NCD3G 635-658 29 0.00655 10.61 Pfam 28-54 (54) Show / Hide 
Range on Protein: 635-658
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CVDCGKGHYGYNG---QCFSCPEGTYS
|..|  |.|  .    .| .|||. ..
CIPCPEGEYSNTTDSYTCTPCPEDQWP
Laminin_EGF RTKC4.AA Laminin_EGF 429-451 30 0.022737 11.51 Pfam 38-59 (59) Show / Hide 
Range on Protein: 429-451
Range on HMM: 38-59/59
Sequence Identity: 30% (7 aa)

RTCQTCAKGYYQDSTGQSECKAC
| |  |. ||..|... . .. |
RHCDRCKPGYWGDPWC-DPPQGC
TNFR RTKC4.AA TNFR 434-468 21 0.024825 10.33 SMART 1-50 (50) Show / Hide 
Range on Protein: 434-468
Range on HMM: 1-50/50
Sequence Identity: 21% (11 aa)

CA--KGYYQDSTGQ----SEC---K--ACPA-----GTMRDATGGTSSTQC
|   .| |... ..    ..|       ||      .  .. |  || |.|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTA-TSNTVC
FU RTKC4.AA FU 533-597 20 0.029681 9.19 SMART 1-48 (48) Show / Hide 
Range on Protein: 533-597
Range on HMM: 1-48/48
Sequence Identity: 20% (14 aa)

SANCKKCAVGSYTPNDGQAYASCLI-CAAGSYQAQLGQTSCTTCADGTTSNNDRTLCVQ-CPAGTAG
.  ||.|             ..|.  |          ...||.|. |   ...   ||. ||.|. .
DGVCKPCH------------PECATGCWGPG------PDQCTSCPHGYYLHHN-GTCVSQCPPGYYP
FU RTKC4.AA FU 465-528 21 0.04145 7.45 SMART 1-48 (48) Show / Hide 
Range on Protein: 465-528
Range on HMM: 1-48/48
Sequence Identity: 21% (14 aa)

STQCLACPVGTEAPLAGSATCSP-CSTGRYQNQTSQATCLSCPEGTYQNVMGATSCRP-CNNGQYQ
...| .|           ..|.  |.  .      . .|.|||.| |..      | . |. | | 
DGVCKPCH----------PECATGCWGPG------PDQCTSCPHGYYLHHN--GTCVSQCPPGYYP
FU RTKC4.AA FU 334-384 26 0.053608 6.11 SMART 1-48 (48) Show / Hide 
Range on Protein: 334-384
Range on HMM: 1-48/48
Sequence Identity: 26% (14 aa)

DRVCRDCPAGTYS--TVENAESCRVCAAGYTSVAGSTSCVEDSDATCPPGTLK
|.||. | ..  .  .  ....|  |. ||        ||.    .||||. .
DGVCKPCHPECATGCWGPGPDQCTSCPHGYYLHHN-GTCVS----QCPPGYYP
TNFR_c6 RTKC4.AA TNFR_c6 505-527 37 0.056876 10.17 Pfam 1-28 (41) Show / Hide 
Range on Protein: 505-527
Range on HMM: 1-28/41
Sequence Identity: 37% (11 aa)

CPEG-TYQNVMG--A--TSCRPCNN-GQY
||.| ||.   .     .||..|.. |||
CPPGKTYTD-WNHVPHCLSCTRCHPMGQY
GCC2_GCC3 RTKC4.AA GCC2_GCC3 549-577 36 0.06728 9.14 Pfam 1-33 (49) Show / Hide 
Range on Protein: 549-577
Range on HMM: 1-33/49
Sequence Identity: 36% (12 aa)

GQAY----ASCLICAAGSYQAQLGQTSCTTCAD
|. |    . |  |  |.|| . ||.||  | .
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPP
FU RTKC4.AA FU 386-457 17 0.070541 4.68 SMART 1-48 (48) Show / Hide 
Range on Protein: 386-457
Range on HMM: 1-48/48
Sequence Identity: 17% (13 aa)

GHLCEACEAGKYSSTTNAATCSAHSAACSAGSYETVAPTSSSDRTCQTCAKGYYQDSTGQSECKA-CPAGTMR
.. |..|           ..|.     |.             . .|..|..|||....  ..| . ||.|. .
DGVCKPCH----------PECAT---GCWGPG----------PDQCTSCPHGYYLHHN--GTCVSQCPPGYYP
TNFR RTKC4.AA TNFR 340-378 20 0.073116 5.42 SMART 1-50 (50) Show / Hide 
Range on Protein: 340-378
Range on HMM: 1-50/50
Sequence Identity: 20% (11 aa)

CP--AGTYSTVENA----ESC---R--VCAA---GYTSVAGSTSCVEDSDATC
|.  .|.|.. .|.    . |   |   |     |   ..   .| . |...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQ---PCTATSNTVC
FU RTKC4.AA FU 599-658 25 0.076758 4.24 SMART 1-48 (48) Show / Hide 
Range on Protein: 599-658
Range on HMM: 1-48/48
Sequence Identity: 25% (16 aa)

GGSCTACSDASAQPQPGSTACVL-CPNGTKASFDKTNCVDCGKGHYGYN-GQCFS-CPEGTYS
.| | .|.            |   |   .      ..|. | .|.|. . |.| | ||.|.| 
DGVCKPCH----------PECATGCWGPG-----PDQCTSCPHGYYLHHNGTCVSQCPPGYYP
GCC2_GCC3 RTKC4.AA GCC2_GCC3 578-635 26 0.093181 8.68 Pfam 1-49 (49) Show / Hide 
Range on Protein: 578-635
Range on HMM: 1-49/49
Sequence Identity: 26% (17 aa)

GTTSNNDRTLCVQCPAGTAGTGGSCTACSDASAQPQPGSTACVLCPNG-T----KASFDKTNC
|| .|.    |. || ||               |.. |...|  || | |    ..|  .. |
GTYYNKGQNPCEPCPRGTY--------------QNEEGQDSCIPCPPGKTTTDYPGSTSESDC
TNFR RTKC4.AA TNFR 505-539 20 0.22109 0.39 SMART 1-50 (50) Show / Hide 
Range on Protein: 505-539
Range on HMM: 1-50/50
Sequence Identity: 20% (10 aa)

CP--EGTYQNVMGAT----SCRPCN----NGQYQDGTVSANCKK-----C
|.  ||.|..  ..|     |.||     . . ..  ....| .     |
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC4.AA TNFR_c6 392-431 23 1.088943 5.79 Pfam 1-41 (41) Show / Hide 
Range on Protein: 392-431
Range on HMM: 1-41/41
Sequence Identity: 23% (10 aa)

CEAG-KYSSTTNA-ATCSAHSAACSA-GSYETVAPTSSSDRTC
|. |  |.. .|   .| .  . |.  |.|..   |. ... |
CPPGKTYTD-WNHVPHCLSC-TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 RTKC4.AA TNFR_c6 340-378 25 1.62068 5.2 Pfam 1-41 (41) Show / Hide 
Range on Protein: 340-378
Range on HMM: 1-41/41
Sequence Identity: 25% (11 aa)

CPAG-TYSTVEN--A--ESCRVCAAGYTSVAGSTSCVEDSDATC
|| | ||.  .|     .||..|     ... . .| . ... |
CPPGKTYTD-WNHVPHCLSCTRCHP-MGQYM-VQPCTWTQNTVC
NCD3G RTKC4.AA NCD3G 463-477 33 2.227924 3.09 Pfam 40-54 (54) Show / Hide 
Range on Protein: 463-477
Range on HMM: 40-54/54
Sequence Identity: 33% (5 aa)

TSSTQCLACPVGTEA
| |..|. || .  .
TDSYTCTPCPEDQWP
TNFR_c6 RTKC4.AA TNFR_c6 652-667 36 3.737883 3.96 Pfam 1-17 (41) Show / Hide 
Range on Protein: 652-667
Range on HMM: 1-17/41
Sequence Identity: 36% (7 aa)

CPEG-TYSDVIDA--SSCK
||.| ||.|  ..  . |.
CPPGKTYTD--WNHVPHCL
Laminin_EGF RTKC4.AA Laminin_EGF 385-406 25 4.032586 3.53 Pfam 36-59 (59) Show / Hide 
Range on Protein: 385-406
Range on HMM: 36-59/59
Sequence Identity: 25% (6 aa)

TGHLCEACEAGKYSSTT-NAA-TC
||  |. |. | .   . . .  |
TGRHCDRCKPGYWGDPWCDPPQGC
GCC2_GCC3 RTKC4.AA GCC2_GCC3 383-408 25 8.059179 2.38 Pfam 4-30 (49) Show / Hide 
Range on Protein: 383-408
Range on HMM: 4-30/49
Sequence Identity: 25% (7 aa)

LKTGH-LCEACEAGKYSSTTNAATCSA
...|.  ||.|. | | .. .  .| .
YNKGQNPCEPCPRGTYQNEEGQDSCIP
Laminin_EGF RTKC4.AA Laminin_EGF 505-522 16 24.000554 0.78 Pfam 43-59 (59) Show / Hide 
Range on Protein: 505-522
Range on HMM: 43-59/59
Sequence Identity: 16% (3 aa)

CPEGTYQNVMGATSCRPC
| .|....  . .... |
CKPGYWGDPWC-DPPQGC
TNFR_c6 RTKC4.AA TNFR_c6 558-579 25 29.170468 0.91 Pfam 1-27 (41) Show / Hide 
Range on Protein: 558-579
Range on HMM: 1-27/41
Sequence Identity: 25% (7 aa)

CAAG-SYQAQLGQ-TSC---TTCAD-GT
|. | .|..  ..   |   |.|   |.
CPPGKTYTD-WNHVPHCLSCTRCHPMGQ
TNFR RTKC4.AA TNFR 705-736 16 0.026872 9.97 SMART 1-50 (50) Show / Hide 
Range on Protein: 705-736
Range on HMM: 1-50/50
Sequence Identity: 16% (8 aa)

CV--PGTFCGT-------ERCASCS--MCSI---GYFAEISGAT----QC
|   .|..| .       ..| .|.  .|.    | ..  ..      .|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC4.AA TNFR_c6 705-723 34 0.622386 6.62 Pfam 1-23 (41) Show / Hide 
Range on Protein: 705-723
Range on HMM: 1-23/41
Sequence Identity: 34% (8 aa)

CVPG-TFCG-T--ERCASCSMCS
| || |..     ..| ||..|.
CPPGKTYTDWNHVPHCLSCTRCH
GCC2_GCC3 RTKC4.AA GCC2_GCC3 708-736 24 3.596234 3.52 Pfam 1-28 (49) Show / Hide 
Range on Protein: 708-736
Range on HMM: 1-28/49
Sequence Identity: 24% (7 aa)

GTFCGTERCASCSMCSIGYFAEISGATQC
||.  ..  . |..| .|.. . .| . |
GTYYNKGQ-NPCEPCPRGTYQNEEGQDSC
NCD3G RTKC4.AA NCD3G 759-786 42 1.7e-08 27.18 Pfam 27-54 (54) Show / Hide 
Range on Protein: 759-786
Range on HMM: 27-54/54
Sequence Identity: 42% (12 aa)

TCEACAAGTYSATADAASCTTCPEGKSS
.|. |..|.|| | |. .||.|||.  .
DCIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKC4.AA GCC2_GCC3 745-785 30 0.000145 17.81 Pfam 1-37 (49) Show / Hide 
Range on Protein: 745-785
Range on HMM: 1-37/49
Sequence Identity: 30% (13 aa)

GTFVAATPTSSTDRTCEACAAGTYSATADAASCTTCPEG-KS
||.      ...  .||.|  |||  ...  ||  || | ..
GTYYN----KGQ-NPCEPCPRGTYQNEEGQDSCIPCPPGKTT
Laminin_EGF RTKC4.AA Laminin_EGF 758-777 27 1.312461 5.26 Pfam 38-59 (59) Show / Hide 
Range on Protein: 758-777
Range on HMM: 38-59/59
Sequence Identity: 27% (6 aa)

RTCEACAAGTY-SATADAA-SC
| |. |. |..  ...| . .|
RHCDRCKPGYWGDPWCDPPQGC
TNFR_c6 RTKC4.AA TNFR_c6 763-783 34 6.408396 3.16 Pfam 1-26 (41) Show / Hide 
Range on Protein: 763-783
Range on HMM: 1-26/41
Sequence Identity: 34% (9 aa)

CAAG-TYSATA--D-AASCTTCPE-G
|. | ||....  .   |||.|.. |
CPPGKTYTDWNHVPHCLSCTRCHPMG
TNFR RTKC4.AA TNFR 913-951 24 0.000267 21.53 SMART 1-50 (50) Show / Hide 
Range on Protein: 913-951
Range on HMM: 1-50/50
Sequence Identity: 24% (12 aa)

CP--GDAFSTTNNA----AQCTPHT--TCAA---GSYVTVYPTVTSNREC
|.  .. .....|.     .|.|..  .|     | |..   | |||..|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR RTKC4.AA TNFR 996-1033 22 0.00265 18.22 SMART 1-50 (50) Show / Hide 
Range on Protein: 996-1033
Range on HMM: 1-50/50
Sequence Identity: 22% (11 aa)

CR--QGYYRDATL-----TSCAPHT--TCTA---GTYEAVAPTVASDRKC
|.  .| |..          | |..  .|.    |.|.    |  |...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
GCC2_GCC3 RTKC4.AA GCC2_GCC3 999-1050 26 0.011706 11.61 Pfam 1-49 (49) Show / Hide 
Range on Protein: 999-1050
Range on HMM: 1-49/49
Sequence Identity: 26% (15 aa)

GYYRDATLTSCAPHTTCTAGTYEAVAPTVASDRKCEACPSG-K---YQPSAYATSC
|.| .. .  |   . |  |||    ... .| .|..||.| .   |. | ....|
GTYYNKGQNPC---EPCPRGTYQ---NEEGQD-SCIPCPPGKTTTDYPGSTSESDC
TNFR RTKC4.AA TNFR 814-852 17 0.012144 13.58 SMART 1-50 (50) Show / Hide 
Range on Protein: 814-852
Range on HMM: 1-50/50
Sequence Identity: 17% (9 aa)

CP--AGKFSAS-------RGQESCQDLATCPT---GYEVATQPTSSTDRVC
|.  .| ....       .  ..|. . .||    | ..    |.  ..||
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC4.AA TNFR_c6 996-1033 26 0.017251 11.94 Pfam 1-41 (41) Show / Hide 
Range on Protein: 996-1033
Range on HMM: 1-41/41
Sequence Identity: 26% (11 aa)

CRQG-YYRD-ATLTSCAPHTTCTA-GTYEAVAPTVASDRKC
|..| .| | ...  | . |.|   |.|.    |  ....|
CPPGKTYTDWNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
GCC2_GCC3 RTKC4.AA GCC2_GCC3 803-828 42 0.022775 10.67 Pfam 1-28 (49) Show / Hide 
Range on Protein: 803-828
Range on HMM: 1-28/49
Sequence Identity: 42% (12 aa)

GTYISDGA--CAACPAGKFSASRGQESC
||| . |   | .|| | .  . || ||
GTYYNKGQNPCEPCPRGTYQNEEGQDSC
TNFR RTKC4.AA TNFR 954-993 22 0.03984 8.18 SMART 1-50 (50) Show / Hide 
Range on Protein: 954-993
Range on HMM: 1-50/50
Sequence Identity: 22% (11 aa)

CSL-GATFSSAINA----AQCQPVT--VCSV---GEEEYTAPTLISNRVC
|   . ....  |.     .|.| .   |.    |...    |  ||.||
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR RTKC4.AA TNFR 1036-1073 22 0.044767 7.65 SMART 1-50 (50) Show / Hide 
Range on Protein: 1036-1073
Range on HMM: 1-50/50
Sequence Identity: 22% (11 aa)

CP--SGKYQPSAYAT----SCLSAT--DCGT----ELAVKAPTPTTDRVC
|.   | |. .  .|     ||. .   |      . ...  |.| ..||
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
FU RTKC4.AA FU 948-1021 17 0.093717 3.2 SMART 1-48 (48) Show / Hide 
Range on Protein: 948-1021
Range on HMM: 1-48/48
Sequence Identity: 17% (13 aa)

NRECQSCSLGATFSSAINAAQCQPVTVCSVGEEEYTAPTLISNRVCEACRQGYYRDATLTSCAPHTTCTAGTYE
...|. |.           ..|     |.             .  | .|. ||| . .   | .  .|..|.| 
DGVCKPCH-----------PECAT--GCWGPG----------PDQCTSCPHGYYLHHN-GTCVS--QCPPGYYP
TNFR_c6 RTKC4.AA TNFR_c6 814-852 21 0.09429 9.42 Pfam 1-41 (41) Show / Hide 
Range on Protein: 814-852
Range on HMM: 1-41/41
Sequence Identity: 21% (9 aa)

CPAG-KFSASRGQ-ESCQDLATCPT-GYEVATQPTSSTDRVC
|| |  ...  .. . |.  ..|.  | ..  . |.  ..||
CPPGKTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 RTKC4.AA TNFR_c6 954-993 28 0.110845 9.18 Pfam 1-41 (41) Show / Hide 
Range on Protein: 954-993
Range on HMM: 1-41/41
Sequence Identity: 28% (12 aa)

CSLGATFSSAINA-AQCQPVTVCSV-GEEEYTAPTLISNRVC
|. | |...  |   .|.. |.|.  |...    |  .|.||
CPPGKTYTD-WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR RTKC4.AA TNFR 872-910 16 0.206516 0.7 SMART 1-50 (50) Show / Hide 
Range on Protein: 872-910
Range on HMM: 1-50/50
Sequence Identity: 16% (8 aa)

CN--STSFAEVAG----LSSCAPHR--ICAP---GSFVQGQPSISNDRSC
|      . .  .    .. | |.|   | |   | ..    .   .. |
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 RTKC4.AA TNFR_c6 1036-1073 34 0.214574 8.2 Pfam 1-41 (41) Show / Hide 
Range on Protein: 1036-1073
Range on HMM: 1-41/41
Sequence Identity: 34% (14 aa)

CPSG-KYQPSAYATSCLSATDCGT-EL-AVKAPTPTTDRVC
|| |  |. ....  ||| | |    . .|.  |.| ..||
CPPGKTYTDWNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 RTKC4.AA TNFR_c6 913-951 29 0.231087 8.09 Pfam 1-41 (41) Show / Hide 
Range on Protein: 913-951
Range on HMM: 1-41/41
Sequence Identity: 29% (12 aa)

CPGD-AFSTTNNAAQCTPHTTCAA-GSYVTVYPTVTSNREC
|| .  .. .|.. .|.. |.|   |.|..   | |.|..|
CPPGKTYTDWNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
NCD3G RTKC4.AA NCD3G 852-878 25 0.357609 5.45 Pfam 28-54 (54) Show / Hide 
Range on Protein: 852-878
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CRRCEAGYVASSINQLACTPCNSTSFA
| .|..| . .. .   ||||  .  .
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKC4.AA GCC2_GCC3 892-927 22 0.558776 6.15 Pfam 14-49 (49) Show / Hide 
Range on Protein: 892-927
Range on HMM: 14-49/49
Sequence Identity: 22% (9 aa)

CAPGSFVQGQPSISNDRSCVACPGD-A---FSTTNNAAQC
|  |..   |.....| || .||.           .. .|
CPRGTY---QNEEGQD-SCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKC4.AA NCD3G 800-820 29 1.126306 3.97 Pfam 31-54 (54) Show / Hide 
Range on Protein: 800-820
Range on HMM: 31-54/54
Sequence Identity: 29% (7 aa)

CEAGTYIS--DG-ACAACPAGKFS
|..|.| .  |   |  || .  .
CPEGEYSNTTDSYTCTPCPEDQWP
Laminin_EGF RTKC4.AA Laminin_EGF 993-1015 30 1.175384 5.43 Pfam 40-59 (59) Show / Hide 
Range on Protein: 993-1015
Range on HMM: 40-59/59
Sequence Identity: 30% (7 aa)

CEACRQGYYRDATLTSCAPHTTC
|. |. ||..|...    |.  |
CDRCKPGYWGDPWC---DPPQGC
NCD3G RTKC4.AA NCD3G 910-929 40 1.685432 3.45 Pfam 28-47 (54) Show / Hide 
Range on Protein: 910-929
Range on HMM: 28-47/54
Sequence Identity: 40% (8 aa)

CVACPGDAFSTTNNAAQCTP
|. ||.  .| | .. .|||
CIPCPEGEYSNTTDSYTCTP
NCD3G RTKC4.AA NCD3G 1033-1052 30 5.18573 2.0 Pfam 28-47 (54) Show / Hide 
Range on Protein: 1033-1052
Range on HMM: 28-47/54
Sequence Identity: 30% (6 aa)

CEACPSGKYQPSAYATSCLS
|. || | |. .  ...|..
CIPCPEGEYSNTTDSYTCTP
Laminin_EGF RTKC4.AA Laminin_EGF 1031-1050 27 20.016342 1.06 Pfam 38-59 (59) Show / Hide 
Range on Protein: 1031-1050
Range on HMM: 38-59/59
Sequence Identity: 27% (6 aa)

RKCEACPSGKY-QPS-AYATSC
|.|. |  | .  |.   . .|
RHCDRCKPGYWGDPWCDPPQGC
HYR RTKC4.AA HYR 1602-1685 33 1.1e-09 33.9 Pfam 80-165 (86) Show / Hide 
Range on Protein: 1602-1685
Range on HMM: 80-165/86
Sequence Identity: 33% (30 aa)

EDLVDPRWVGCPTGRITYLVSQPTLSTTADWTEPQATDNVG---LRETHSNYAPGDTLDMT-DSPFNVIYTAVDLSGRTA-TCEFTVVL
 |   |.   ||.. |.. |.  |...   |||| |||| |    . .  .. |||..    .    | ||. | .| .| || |||  
VDTTPPTVENCPNN-IFRTVELGTSTVNVFWTEPTATDNSGDIQANLISRTAQPGDFFPVGEQTT--VTYTFQDNAGNQADTCTFTVTV
HYR RTKC4.AA HYR 1895-1931 29 0.08557 7.93 Pfam 1-37 (86) Show / Hide 
Range on Protein: 1895-1931
Range on HMM: 1-37/86
Sequence Identity: 29% (11 aa)

TDFVDPTLHGCSSNLTRVLPSNSNAVAFSWPRPTYSD
.|   ||   |..| .|. ..... |. .|. || .|
VDTTPPTVENCPNNIFRTVELGTSTVNVFWTEPTATD
HYR RTKC4.AA HYR 2078-2157 29 1.2e-07 27.26 Pfam 1-86 (86) Show / Hide 
Range on Protein: 2078-2157
Range on HMM: 1-86/86
Sequence Identity: 29% (26 aa)

RDEQPPRV-ICPTSPVALVSTAASPNVVYNYTLPLAEDNSG----SVFVSDNNTAAALPTG-RTTVVIVVSDAANNAV-TCVVHVDV
 | .||.|  ||.. .. . .  .. |.  .| | | ||||    .. .  .   . .|.|  |||  ...|.| |   ||.. | |
VDTTPPTVENCPNN-IFRTVELGTSTVNVFWTEPTATDNSGDIQANLISRTAQPGDFFPVGEQTTVTYTFQDNAGNQADTCTFTVTV
HYR RTKC4.AA HYR 2051-2077 34 7.256839 1.58 Pfam 58-86 (86) Show / Hide 
Range on Protein: 2051-2077
Range on HMM: 58-86/86
Sequence Identity: 34% (10 aa)

PIG-SASVNATVRDAYGNSQ-TVMVPVVV
|.| . .| .|..|. ||.  |  . | |
PVGEQTTVTYTFQDNAGNQADTCTFTVTV
Kinase RTKC4.AA RTKC 2243-2499 65 2e-213 710.96 In-house 1-261 (261) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-261/261
Sequence Identity: 65% (172 aa)

LTLLEELGRGAFGLVYKGLLEEPP-NPGFLVAVKSLHDAADEKARQELLEEAAVMAQFNHRNVVKLVGVVTVGRPILVVIEFCEKGALKGYLEKH-DLTQ
||||.||||||||.|||.|||||. .||.|||.||||..|....||||||||||||||.|.|||.|.||||||.|||||.||||.|.||.||... |.|.
LTLLDELGRGAFGIVYKALLEEPGGMPGYLVACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYLMNNPDCTE

HQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAREA--DGGAEETYYRATSSQIPIRWTAPEAMEERKFSEKSDVWAGGILFYEI
|||.||....|.|.||||...|.||||||||||.|||||.||||||||||.  .....|.|||..|...|.|||||||...|||||||||||.|||.|||
HQKVRFCYQCASGMEHIHSFGFIHRDVAARNVLLSSDLTCKVADFGLARESPCNDDSHEAYYRSRSGNLPVRWTAPEALDDRKFSEKSDVWAFGILMYEI

LTRAALPYDGWSNQRVWVEVCAGYKLQPPTGTPTELCDLLNDMWSMNPKERPDFSGVVERL
.|.|..||||||||||||||||||.|..|.....|..|...|.|...|..||.||.||..|
YTKAEMPYDGWSNQRVWVEVCAGYRLPCPEDCHKEVYDMMMDCWMHTPHDRPTFSEVVHWL
Kinase RTKC4.AA RTKD 2243-2501 44 3.8e-110 372.24 In-house 1-262 (262) Show / Hide 
Range on Protein: 2243-2501
Range on HMM: 1-262/262
Sequence Identity: 44% (118 aa)

LTLLEELGRGAFGLVYKGLLEE---PPNPGFLVAVKSLHDAADEKARQELLEEAAVMAQFNHRNVVKLVGVVTVGRPILVVIEFCEKGALKGYLEKH--D
...|| .| | .| | |..|||      |||||||| .  . .| .  |.. ||| |||||| |.| | ||||.  |   | |.|| |.|  || .   |
IKCLEPIGKGNWGMVFKAMLEEHIMKGIPGFLVAVKIMKNQSQE-QVMEMTREAAFMAQFNHDNIVRLHGVVTTNQPHIMVMEYCEHGSLQAYLRENGED

LTQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAR-EADGGAEETYYRATSSQIPIRWTAPEAMEERKFSEKSDVWAGGILFY
    . .|.|.|.|.||. .|    .|||.||||.|..|.. ||..|||| | .|.|  |  || .    ||.|| |||. || |||  ||||  ... |
MDNQHRFRMARDVAMGLAYLHFRGCCHRDIAARNILLDSNYRAKIGDFGLTRQQANGDSE--YYISHGQAIPVRWCAPEVLEEHKFSQASDVWSWAVFVY

EILTRAALPYDGWSNQRVWVEVCAGYKLQPPTGTPTELCDLLNDMWSMNPKERPDFSGVVERLEE
|| | |.|||.. .||.||  | .|| |. |...| .. .|  | |.  ||||| .  ||.....
EIWTQAQLPYRDMHNQKVWHYVIQGYRLTRPMQCPRDIWALMMDCWAEDPKERPRMCQVVDQMTK
Kinase RTKC4.AA TK 2243-2499 22 9.5e-107 358.98 In-house 1-486 (486) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

LTLLEELGRGAFG---LVYKGLLEEPP---NPGF-------------------LVAVKSLHDAADEKARQELL-------------EEAAVMAQFN----
.||...||.|.||    ||||......   ...|                    |||| |.. ... ......             |||..|....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNVVKLVGVVTVG------------RPILVVIEFCEKGA----LKGYLEKHD----------------------------------------------
 | |.|.|.||.| |            .|...| |....|     |. || |..                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTQHQKLRFALDAARGLEHIHAY------NFVHRDVAARNVLVSSDLT-----------AKVADFGLAR
                               || ||.| .....|.|.|..|.       ||||||.||||.||.....           .|.|||||.|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

E------ADGGAEETYYRAT------------------------SSQIPIRWTAPEAME---------ERKFSEKSDVWAGGILFYEILTRA-ALPYDGW
.       | . .. |||..                        . ..||||.|||...         ..||..|||||. |.| .||.|.. . .| |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SNQRVWV-----------------------EVCAGYKLQPPTGTP--------------TELCDLLNDMWSMNPKERPDFSGVVERL
|||.||.                       ||  .. . .| . |              .|. ||. . |. .|..||.|| ..|.|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKC4.AA Pkinase_Tyr 2243-2499 38 3.3e-106 360.31 Pfam 1-270 (270) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-270/270
Sequence Identity: 38% (105 aa)

LTLLEELGRGAFGLVYKGLLE-EPPNPGFLVAVKSLHDAADEKA--RQELLEEAAVMAQF-NHRNVVKLVGVVT-VGRP--ILVVIEFCEKGALKGYLEK
.|....||.|||| |||| .  .| |..  ||||.| . |....  |.....||..| |. .| |.|.|.||.|  |.|  |..| |....| |. || |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H-----DLTQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAREADGGAEETY-YRATSSQIPIRWTAPEAMEERKFSEKSDVW
|      || ...| .... |.|.|. .. |..|||.||||.||......|..||||||      ...| . .... .||.|.|||.. ..||..|||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

AGGILFYEILTRAALP-YDGWSNQRVWVEV-CAGYKLQPPTGTPTELCDLLNDMWSMNPKERPDFSGVVERL
. |.| .||.|. . | | |.||..|   .   || . .| ..| |. ||. . |  .|..|| || ..|.|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKC4.AA TyrKc 2243-2499 35 8.49999999999e-106 358.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-280/280
Sequence Identity: 35% (104 aa)

LTLLEELGRGAFGLVYKGLLEEPPNPGFLVAVKSLHDAADEKARQELLEEAAVMAQF--NHRNVVKLVGVVTVG-------RPILVVIEFCEKGALKGYL
.||...||.|||| |||| .         ||||.|.. |    |.....|| .| ..  .| |.|.|.||.| .        |...| |....|.|| ||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

EKHD--LTQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAREADGG----AEETYYRAT---SSQ--IPIRWTAPEAMEERKF
 ||   |.  ..| |....|.| |..|  |..||| ||||.||....|.|..||||.|. . .    ... |||..   ..   .||||.|||.. ..||
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SEKSDVWAGGILFYEILTRAALPYDG-----WSNQRVWVEVCAGYKLQPPTG--------TPTELCDLLNDMWSMNPKERPDFSGVVERL
..|||||. |.. .||.|. . || |      |||.|   | .|| . .|           |.|. ..  . |  .|..|| || ..|..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKC4.AA UTK 2243-2499 36 1.5e-101 343.71 In-house 1-296 (296) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-296/296
Sequence Identity: 36% (109 aa)

LTLLEELGRGAFGLVYKGLLEEPPNPGFL--VAVKSLH-DAADEKARQ---ELLEEAA---VMAQFN-HRNVVKLVGVVTVGRPILVVIEFCEKGALKGY
. |...||.|||| |.|. ........ .  |||| .  .|......    ...|||.   .|.||. |.||..||||.| . |...|.|..|.| |  |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LEKHDL---------TQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSD-------LTAKVADFG---LAREADG------GAEETYYRAT-SSQ
| .|           | ||.| .|.| |||....|  .|||||.||||.|| ..       ...|.||||   ..|.. .       .|  ||.|.   .
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

IPIRWTAPEAMEER-KFSEKSDVWAGGILFYEILTRAALPYDGWSNQRVWVEVCAG--YKLQPPTGTPTELCDLLNDMWSMNPKERPDFSGVVERL
.||||.||||. .. .|..|||||. |.. .||.|...||| |.||..||..||.|  | . .| . | .. .|... | ..| |||||  .|...
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKC4.AA Fer 2243-2500 32 7.9e-85 288.12 In-house 1-283 (283) Show / Hide 
Range on Protein: 2243-2500
Range on HMM: 1-283/283
Sequence Identity: 32% (91 aa)

LTLLEELGRGAFGLVYKG--LLEEPPNPGFL-----VAVKSLHDA-ADEKARQELLEEAAVMAQ-FNHRNVVKLVGVVTVGRPILVVIEFCEKGALKGYL
 || . ||.|||| ||||   | .    ..      |.|| .. . |... ..|.. || .| . ..| ||||. || .   ||..|.|||  |.|. ||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

EK-HD--LTQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSS-DLTAK--VADFGLAREADGGAEETYYRATSSQIPIRWTAPEAMEERKFSEKSD
 | ..  ..  .|.|....||.|.|..|. | .|||.||||.|..  ..  |  ..|||..|. ... .  . . .. ..||||.|||... . .|.|.|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWAGGILFYEILTRAALPYDG---------WSNQRVWVEVCAGYKLQPPTGTPTELCDLLN-DMWSMNPKERPDFSGVVERLE
||. |.. .|| |..| || |         . .|.. . ...|| ...| ..|.|.  ..  . | ..|..|| .. ....|.
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase RTKC4.AA Eph 2243-2499 39 6.7e-81 271.48 In-house 1-264 (264) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-264/264
Sequence Identity: 39% (105 aa)

LTLLEELGRGAFGLVYKGLLEEP-PNPGF---LVAVKSLHDAADEKARQELLEEAAVMAQFNHRNVVKLVGVVTVGRPILVVIEFCEKGALKGYLEKHD-
... . .| | || |..| |  | .       .||.| | . . ||.| . | ||..| ||.| |...| |||| .||. .|.|. | |.|  .| .|| 
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

-LTQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAREADGGAE-ETYYRATSSQIPIRWTAPEAMEERKFSEKSDVWAGGILF
 .|  | .      | |       |.|||| ||||.||.|.|  ||.|||| |. .  .  |  |  ... ||||||||||.  |||.  ||||  ||. 
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVM

YEILTRAALPYDGWSNQRVWVEVCAGYKLQPPTGTPTELCDLLNDMWSMNPKERPDFSGVVERL
 |...    ||  .||| |  ..  || | || . |. |  |  | | . ...|| |. .|  |
WEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase RTKC4.AA SFK-Src 2243-2503 37 2.4e-77 228.63 In-house 1-259 (259) Show / Hide 
Range on Protein: 2243-2503
Range on HMM: 1-259/259
Sequence Identity: 37% (101 aa)

LTLLEELGRGAFGLVYKGLLEEPPNPGFLVAVKSLHDAADEKARQELLEEAAVMAQFNHRNVVKLVGVVTVGRPILVVIEFCEKGALKGYLEK---HDLT
  | . || | || |.||      |    |||| |  .|     .| |.||.|| .  | | ..|  | | | || .. | .  | |  ||     . |.
IRLEKKLGSGQFGDVWKGRW----NNTTEVAVKTLKPGA--MSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLR

QHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAREADGGAEET-YYRATSSQIPIRWTAPEAMEERKFSEKSDVWAGGILFYEI
  |    | . | |.    | |||||| |||||||    . ||.|||..|    ....  |   .    ||.|||||||   .|| |||||. ||| .||
MPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVL--AQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEI

LTRAALPYDGWSNQRVWVEVCA--GYKLQPPTGTPTELCDLLNDMWSMNPKERPDFSGVVERLEELL
 |    ||.| .|. |   |    || .  |...| |.  .. | |  .| .|| |     ..|.  
VTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase RTKC4.AA Src 2243-2499 36 1.7e-74 252.54 In-house 1-255 (255) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-255/255
Sequence Identity: 36% (95 aa)

LTLLEELGRGAFGLVYKGLLEEPPNPGFLVAVKSLHDAADEKARQELLEEAAVMAQFNHRNVVKLVGVVTVGRPILVVIEFCEKGALKGYLEK----HDL
..|...||.| || |..|.     |    ||||.|  .    . . .|.|| .| .. | ..|.|  |.. . ||. | |. ..| |  || |    . |
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL

TQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAREADGGAEETYYRATSSQIPIRWTAPEAMEERKFSEKSDVWAGGILFYEI
   | . .|   |.| . . . |..||| |||||||. .. .|||||||||  . . .. |   . . .||.||||||  ...|. |||||  ||| .||
HLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKED-DDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEI

LTRAALPYDGWSNQRVWVEVCAGYKLQPPTGTPTELCD-LLNDMWSMNPKERPDFSGVVERL
 |.   || |..|. |  .| .||..  |.. | || . ..   |   |..|| |    . |
VTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase RTKC4.AA Csk 2243-2499 40 4.5e-72 245.23 In-house 1-251 (251) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-251/251
Sequence Identity: 40% (105 aa)

LTLLEELGRGAFGLVYKGLLEEPPNPGFLVAVKSLHDAADEKARQELLEEAAVMAQFNHRNVVKLVGVVTVGRP--ILVVIEFCEKGALKGYL---EKHD
|.|.|. | | || |  | .      .  |||| . . . . | | .| ||.|| |  |.| |.|.||. .. .  . .|.|.  || |  ||   ..| 
LHLGECIGHGEFGDVMQGEYQ-----NRKVAVKCIKCDGNGMA-QAFLAEASVMTQLRHPNLVQLIGVI-LHQKNHLYIVMEYMSKGNLVDYLRSRGRHV

LTQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAREADGGAEETYYRATSSQIPIRWTAPEAMEERKFSEKSDVWAGGILFYE
.|. | | ||.| . | .   . .||||| ||||.||| |. ||| |||||.|.  . ..    .||. .|| ||||||. . ||| |||||  |||  |
ITRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDD----STSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWE

ILTRAALPYDGWSNQRVWVEVCAGYKLQPPTGTPTELCDLLNDMWSMNPKERPDFSGVVERL
|      ||   . . |   |  ||.  .| | | .   . .. | .||..|| |  |.|.|
IYSFGRVPYPRIPLKDVVKHVEKGYRMEAPEGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL
Kinase RTKC4.AA TK-Unique 2243-2499 30 1.1e-66 227.87 In-house 1-294 (294) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-294/294
Sequence Identity: 30% (89 aa)

LTLLEELGRGAFGLVYKGLLEEPP--NPGF-LVAVKSLHDAADEKARQELLEEAAVMAQFN-HRNVVKLVGVVTVGR-PILVVIEFCEKGALKGYLEKHD
|......|.|||| |..| .....  .  .  |||| |.| |..  .|..| |...| .   | |.|...|. |    | . ..|.|..| | .|| .  
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

---------------------------LTQHQKLRFALDAARGLEHIHA--YNFVHRDVAARNVLVSSDLTAKVADFGLAREADGGAEETYYRATS-SQI
                           .. .. ..|| . |.|.|...   ...||||..|||||...|...|..|||.||. .   .. | . .| . |
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT--NGVYSMMCSQGRI

PIRWTAPEAME--ERKF-SEKSDVWAGGILFYEILTRAALPYDGWSNQRVWVEVCAGYKLQPPTGT-PTELCDLLNDMWSMNPKERPDFSGVVERL
|||| |||..   .. . ..|||||. |.| .||.|  | || | .. ..  .. .|| .. | .  . |.  |.   |. .|.|||.|. .. ||
PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKC4.AA S_TKc 2243-2503 21 3.4e-52 180.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 2243-2503
Range on HMM: 1-231/231
Sequence Identity: 21% (59 aa)

LTLLEELGRGAFGLVYKGLLEEPPNPGFLVAVKSLHDAADEKARQELLEEAAVMAQFNHRNVVKLVGVVTVGRPILVVIEFCEK--GALKGYLEKHD---
 ..|...|.|||| |||.   .    | .||.| ..        . .. | ... . .| |.||| .|      . .| |.|.   | |. |..|.    
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LTQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTAKVADFGLAREADGGAEETYYRATSSQIPIRWTAPEAMEERKFSE-KSDVWAGG
    ..  .  ...   ...||..|  ...|||.   |.|...  . |..||||||.            |.      . ||| .   ...  |.|.|. |
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

ILFYEILTRAALPYDGWSNQRVWVEVCAGYKLQPPTGTPTELCDLLNDMWSMNPKERPDFSGVVE-----RLEELL
...|| |.    |..   .. .  ...           . |..|... .. ..|..||    . .     .. . .
CILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKC4.AA Pkinase 2243-2499 20 3.1e-42 150.4 Pfam 1-293 (293) Show / Hide 
Range on Protein: 2243-2499
Range on HMM: 1-293/293
Sequence Identity: 20% (63 aa)

LTLLEELGRGAFGLVYKGLLEEPPNPGFLVAVKSLH-DAADEKARQELLE--EAAVMAQFNHRNVVKLVGVVTVGRPILVVIEFCEKG----ALKGYLE-
..... .|.|.|| |||.     .    .|||| .  . .... .|...   |...|. .|| |.|.| .... .. | .| |.||.|     |. |.. 
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

--KHDL--TQHQKLRFALDAARGLEHIHAYNFVHRDVAARNVLVSSDLTA----KVADFGLAREADGGAEETYYRATSSQIPIRWTAPEAME-ERKFSEK
  .  .  . ..  ....  .||||..|. ...|||.   |.|.... .     |..|||||. .|   .  .  .|.    ... |||     .. . |
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

SDVWAGGILFYEILTRAALPYDG------WSNQRVWVEVCAGYKLQPPTGTP-------------------TELCDLLNDMWSMNPKERPDFSGVVER--
.|.|. |...|| |..  . ..         .|..    .. .. . |.  .                    |..|...... ..||.|| .  ...   
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

L
.
F
CAP_GLY RTKC4.AA CAP_GLY 2681-2725 40 5e-12 43.98 Pfam 1-49 (72) Show / Hide 
Range on Protein: 2681-2725
Range on HMM: 1-49/72
Sequence Identity: 40% (20 aa)

IGKRVVV--QGYRSLGYLRFYGHHH-EKGGVRCGVEL-DEPEGRNDGTV
.| |..|  .| . .| .|..|  .  |.|. .|||. ||| | |||.|
VGDRCEVWDGGGGRRGTVRYVGPTPGFKPGTWVGVEWDDEPRGKNDGSV
PA26 RTKC4.AA PA26 3178-3204 48 0.000226 17.02 Pfam 79-105 (477) Show / Hide 
Range on Protein: 3178-3204
Range on HMM: 79-105/477
Sequence Identity: 48% (13 aa)

LAASRHCCQYLIDIHLHHFRELGGDEE
.||.|| | ||...| | | . |||..
MAAARHQCSYLVNHHEHEFLQNGGDPR
PA26 RTKC4.AA PA26 3156-3177 36 0.089658 7.32 Pfam 30-51 (477) Show / Hide 
Range on Protein: 3156-3177
Range on HMM: 30-51/477
Sequence Identity: 36% (8 aa)

AFESDGRVSNMTRVMATHPKFL
.| . ||. . |.||. ||...
EFMFHGRWDHVTQVMGWHPQYH
PA26 RTKC4.AA PA26 3209-3244 44 1.1e-10 40.52 Pfam 152-187 (477) Show / Hide 
Range on Protein: 3209-3244
Range on HMM: 152-187/477
Sequence Identity: 44% (16 aa)

DNWSLPELMQAVLLLSHFHALAGFCLATGLLPEVDL
..|||.|| .|..|..|||.|..|    |. ||.|.
HSWSLCELVHAMVLMCHFHSLCSFVFCCGIHPECDC