Gene RTKB5 (M.brevicollis)

RTKB5

Species: M.brevicollis
Alias: RTKB5
External Links:
Annotation:

Classification

Group: TK
Family: RTKB

Sequence

Name Sequence Type Origin Length Description Download
RTKB5.AA Protein None 1039 None Fasta, JSON
RTKB5.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of RTKB5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NCD3G RTKB5.AA NCD3G 269-295 29 0.052298 7.93 Pfam 28-54 (54) Show / Hide 
Range on Protein: 269-295
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CVPCSGAAYRDALSMDQCAACPVGSEP
|.|| .  | .   ...|  || .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB5.AA NCD3G 237-262 25 0.092815 7.19 Pfam 28-54 (54) Show / Hide 
Range on Protein: 237-262
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CDTCAAGSYRS-AGMNECAVCADGTEP
|  |..|.| .  .. .|  | ..  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKB5.AA GCC2_GCC3 259-292 32 0.285193 7.1 Pfam 1-34 (49) Show / Hide 
Range on Protein: 259-292
Range on HMM: 1-34/49
Sequence Identity: 32% (11 aa)

GTEPSGNLASCVPCSGAAYRDALSMDQCAACPVG
||  ..... |.||    |..  ..| | .||.|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPG
GCC2_GCC3 RTKB5.AA GCC2_GCC3 227-249 26 3.30336 3.64 Pfam 1-23 (49) Show / Hide 
Range on Protein: 227-249
Range on HMM: 1-23/49
Sequence Identity: 26% (6 aa)

GSELNAERSGCDTCAAGSYRSAG
|  .|.. . |  |  |.|.. .
GTYYNKGQNPCEPCPRGTYQNEE
NCD3G RTKB5.AA NCD3G 334-360 29 0.003896 11.28 Pfam 28-54 (54) Show / Hide 
Range on Protein: 334-360
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CVPCSGAGYRDTSSMDQCAACAVGSEP
|.|| .  | .|. ...|  |  .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB5.AA NCD3G 302-327 25 0.092815 7.19 Pfam 28-54 (54) Show / Hide 
Range on Protein: 302-327
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CDTCAAGSYRS-AGMNECAVCADGTEP
|  |..|.| .  .. .|  | ..  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKB5.AA GCC2_GCC3 308-351 32 0.252853 7.27 Pfam 1-49 (49) Show / Hide 
Range on Protein: 308-351
Range on HMM: 1-49/49
Sequence Identity: 32% (16 aa)

GSYRSAGMNECAVCADGT-EPSGDQASCVPCSGA-G---YRDTSSMDQC
| | ..| |.|  |  ||  ....| || ||..  .   |   .| ..|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKB5.AA NCD3G 399-425 29 0.000418 14.16 Pfam 28-54 (54) Show / Hide 
Range on Protein: 399-425
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CVSCTGAEYRDASSMDQCAACPVGSEP
|. |.. || . . ...|  || .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKB5.AA GCC2_GCC3 389-422 32 0.079741 8.9 Pfam 1-34 (49) Show / Hide 
Range on Protein: 389-422
Range on HMM: 1-34/49
Sequence Identity: 32% (11 aa)

GTEPSGSQASCVSCTGAEYRDASSMDQCAACPVG
||  ...|. |..|    |.. ...| | .||.|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPG
NCD3G RTKB5.AA NCD3G 367-392 25 5.307715 1.97 Pfam 28-54 (54) Show / Hide 
Range on Protein: 367-392
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CDTCVAGSYRS-AGMNGCAVCADGTEP
|  | .|.| .  ..  |  | ..  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB5.AA NCD3G 464-490 29 0.001456 12.55 Pfam 28-54 (54) Show / Hide 
Range on Protein: 464-490
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CVPCSGAAYRDASSMDQCAACPVGSEP
|.|| .  | . . ...|  || .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKB5.AA GCC2_GCC3 438-481 32 0.22418 7.44 Pfam 1-49 (49) Show / Hide 
Range on Protein: 438-481
Range on HMM: 1-49/49
Sequence Identity: 32% (16 aa)

GSYRSAGMNGCAVCADGT-EPSGSQASCVPCSGA-A---YRDASSMDQC
| | ..| | |  |  ||  ....| || ||..      |  ..| ..|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKB5.AA NCD3G 432-457 25 1.367155 3.72 Pfam 28-54 (54) Show / Hide 
Range on Protein: 432-457
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CDMCAAGSYRS-AGMNGCAVCADGTEP
|  |..|.| .  ..  |  | ..  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
Kinase RTKB5.AA RTKB 596-858 67 5.1e-201 674.09 In-house 1-264 (264) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-264/264
Sequence Identity: 67% (177 aa)

LWIGPKLGNGAFGEVFQAWIAHQSADGKQACAAKRLPPGASYEAHQDFRAELALMKELGTHPNVIGLVGHCFQDEPPILLVELAELGNLRDLLRKGRASE
.|.|.||||||||||||||.........|.||||.|.||||||..|||..|...|||||.||||||..|||.||||.||||||.|||||||.||..|||.
VWLGEKLGNGAFGEVFQAWVRNRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRASQ

GRAQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQMTCKVSDFGLARTLDGEQYTTTTTRLPVKWMAPESLGRRIYTTKS-DVWAFGVTM
...||....||..||.||..|||||.|..||||||.|||||||||..||..|||.||..|.|.|.||.||||.|||||||...||||||| |||.|||||
HNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGVTM

WEIFSLGGTPYQEYRNAHILNLLESGYRLPVPMQMPSKAHGIMQQCWSMEAEERPAFAELIGSF
||||||||||||.|||..|...||||.|||.|.|||..|..|||.||.|||..||.|.||...|
WEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase RTKB5.AA Pkinase_Tyr 596-858 41 2e-111 377.96 Pfam 1-270 (270) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-270/270
Sequence Identity: 41% (112 aa)

LWIGPKLGNGAFGEVFQAWIAHQSADGKQACAAKRLPPGASYEA--HQDFRAELALMKELGTHPNVIGLVGHCF-QDEP--PILLVELAELGNLRDLLRK
. .| ||| ||||||...    .  ..|. .| | |..||. |.  ..|| .|...||.|| |||.. |.| |  |.||  ... .|....|.|.| |||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

GRASEGRAQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQMTCKVSDFGLARTL--DGEQ-YTTTTTRLPVKWMAPESLGRRIYTTKSDV
 |      |. .. .|...|.|| .||..||..  |||||||||.||. ....|..||||||..  |..  .... ..||.||||||..  ...||||||
HR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WAFGVTMWEIFSLGGTP-YQEYRNAHILNLL-ESGYRLPVPMQMPSKAHGIMQQCWSMEAEERPAFAELIGSF
|.|||.|||||..|..| |..  |. ..... |.|||.| |.  | . . .|.|||  ..|.|| |.|..  .
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKB5.AA TyrKc 596-858 36 4e-110 373.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-280/280
Sequence Identity: 36% (108 aa)

LWIGPKLGNGAFGEVFQAWIAHQSADGKQACAAKRLPPGASYEAHQDFRAELALMKELG-THPNVIGLVGHCFQD-------EPPILLVELAELGNLRDL
.  | |||.||||||...          . .| | | ..|    ..||. |. .|..||  |||.. |.| | |.       ||. ...|....|.|.| 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LRKGRASEGRAQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQMTCKVSDFGLARTLDGE-------QYTTT----TTR--LPVKWMAPE
||| |         .. .|..|| || .||..|... .|||||||||.||. . |.|.|||||.| .. .       .| ..     ..  ||..|||||
LRKHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

SLGRRIYTTKSDVWAFGVTMWEIFSLGGTPYQE-----YRNAHILNLLESGYRLPVPMQ--------MPSKAHGIMQQCWSMEAEERPAFAELIGSF
..  ...|||||||.|||.|||||..|..|| .       |.........|||.| |          .|.. . ||.|||  ..|.|| |.|..  |
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKB5.AA TK 596-858 22 9.5e-109 365.81 In-house 1-486 (486) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-486/486
Sequence Identity: 22% (109 aa)

LWIGPKLGNGAFG---EVFQAWIAHQS---------------------ADGKQACAAKRLPPG--ASYEAHQD--------------FRAELALMKE-LG
. .| ||| |.||   ||....   ..                      .||. .| | | .|  .| |...|              . .|...|.. ||
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

THPNVIGLVGHCFQD------------EPPILLVELAELGN----LRDLLRKGRA---------------------------------------------
 |||.. |.|.|.|.            ||.....|....|.    ||| ||| |                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------SEGRAQSHS--------------VGQLIEFCRQIVNGMAFLEQNDV------IHRDLAARNVLVDQQMT-----------CKVSDFG---
          . . .. ..              . ||. .|.|| .||..|... .      .||||||||.||.....           ||..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARTLDGEQYTTTTT--------------------------RLPVKWMAPESLGRRI---------YTTKSDVWAFGVTMWEIFSLG-GTPYQEY
     ||| .. ... ....                          .||..|||||.|  |.         .|||||||.|||.|||||..| ...| . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

RN---------AHILNLLESG--------------YRLPVPMQMP--------------SKAHGIMQQCWSMEAEERPAFAELIGSF
 |         . ....|..|              .|.| |...|                 . .|||||. ..|.|| |..|   .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKB5.AA UTK 596-858 33 6e-91 308.45 In-house 1-296 (296) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-296/296
Sequence Identity: 33% (99 aa)

LWIGPKLGNGAFGEVFQAWIAHQS-ADGKQACAAKRLPPGASYEAHQD----FRAELA---LMKELGTHPNVIGLVGHCFQDEPPILLVELAELGNLRDL
. .| .|| ||||||. |   . |   .....| | . ..|. .  ..    |. | .   .|| .  ||||..||| |.|.||.....|..| |.||..
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRKGRASEG-RAQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQ-------MTCKVSDFG---LARTLD---------GEQYTTT--TTR
||. | . . .  . .  |.......| .||..|..  ..||||||||.||...       |.||..|||   ..| .          . .| .    .|
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVKWMAPESLGRR-IYTTKSDVWAFGVTMWEIFSLGGTPYQEYRNAHILNLLESG--YRLPVPMQMPSKAHGIMQQCWSMEAEERPAFAELIGSF
.|..|||||.|  .  .|||||||.|||..|||.. | .|| .. |. ..  .. |  ||.| | ..|     .|..|| .. .||| | .|   .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKB5.AA TK-Unique 596-858 36 1.6e-90 307.04 In-house 1-294 (294) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-294/294
Sequence Identity: 36% (107 aa)

LWIGPKLGNGAFGEVFQAWIAHQS-ADGKQ-ACAAKRLPPGASYEAHQDFRAELALMKELGTHPNVIGLVGHCFQD-EPPILLVELAELGNLRDLLRKGR
| .| ..| ||||.|. . .   .  ..||   | | |  .|. . .|||  |...||||| |||.. ..| |  . ||. .. | .. |||...||. |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

AS-------------------EGRAQSHSVGQLIEFCRQIVNGMAFLEQ--NDVIHRDLAARNVLVDQQMTCKVSDFGLARTLD-GEQYTTTTT--RLPV
                     . |  . | ..|. |. || .||..|..    ..||||.|||||.    .||..|||.|| .. ...| ....  |.|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWMAPESLG--RRIY-TTKSDVWAFGVTMWEIFSLGGTPYQEYRNAHILNLLESGYRLPVPMQM-PSKAHGIMQQCWSMEAEERPAFAELIGSF
.|||||||   ...| |||||||.|||.|||||.||..|| ..... |..... |||.|.| .  .   . .|..||. |.|||| |....  .
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKB5.AA Src 596-858 38 6.5e-81 274.64 In-house 1-255 (255) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-255/255
Sequence Identity: 38% (104 aa)

LWIGPKLGNGAFGEVFQ-AWIAHQSADGKQACAAKRLPPGASYEAHQDFRAELALMKELGTHPNVIGLVGHCFQDEPPILLV-ELAELGNLRDLLRKGRA
.    |||.| ||||..  |      .|.   | | | ||    . ..| .|  .||.|  |.... |   | |.| ||. | |. . |.| | |.|   
IKLCRKLGQGQFGEVWMGYW------NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEE-PIYIVTEYMSHGSLLDYLKK---

SEGRAQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQMTCKVSDFGLARTLD--GEQY-TTTTTRLPVKWMAPESLGRRIYTTKSDVWAF
 .|. .. .. |||..  |. .|||.||.. .||||||||||||...  ||| |||||| ..   . |   .  ..|.||.||| . .. .|.||||| |
-DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSF

GVTMWEIFSLGGTPYQEYRNAHILNLLESGYRLPVPMQMPSKAHG-IMQQCWSMEAEERPAFAELIGSF
|. ..||.. | .||   .|.  |  .| |||.| |.. | . .  ||.|||  ..|.|| |. |   .
GILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase RTKB5.AA Tie 604-858 40 7.3e-79 239.53 In-house 1-267 (267) Show / Hide 
Range on Protein: 604-858
Range on HMM: 1-267/267
Sequence Identity: 40% (110 aa)

NGAFGEVFQAWIAHQSADGKQACAAKRLPPGASYEAHQDFRAELALMKELGTHPNVIGLVGHCFQDEPPILLVELAELGNLRDLLRKGR---------AS
 | || |..| |      .|   | |..  .|| . |.||  || .|  .|.|||.| ||| | .     . .| |  ||| | ||| |          .
EGNFGQVMKAMIKKDG--LKMEVAIKMMKEYASEDDHRDFMGELEVMCKVGHHPNIINLVGACEHRGYLYVAIEYAPYGNLLDFLRKSRVIETDPAFARE

EGR------AQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQMTCKVSDFGLARTLDGEQYTTTTT-RLPVKWMAPESLGRRIYTTKSDV
..       | . |  |...|   . .|| .| | ..|||||||||.|| . . ||..||||.|    | |  .|  ||||.||| |||   .|||||||
HTTRFKVNVASTLSSQQILHFAADVARGMQYLSQKQCIHRDLAARNILVCENYVCKIADFGLSRG--DEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDV

WAFGVTMWEIFSLGGTPYQEYRNAHILNLLESGYRLPVPMQMPSKAHGIMQQCWSMEAEERPAFAELIGSF
|..|| .||| |||||||     | . . |  |||.  |.    . . .|.|||     |||.||... ..
WSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYDLMRQCWRDRPYERPPFAQIAVQL
Kinase RTKB5.AA FGFR 596-858 34 1.4e-76 260.52 In-house 1-293 (293) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-293/293
Sequence Identity: 34% (102 aa)

LWIGPKLGNGAFGEVFQAWIA---HQSADGKQACAAKRLPPGASYEAHQDFRAELALMKELGTHPNVIGLVGHCFQDEPPILLVELAELGNLRDLLRKGR
| .|  || |.||.|  |       . .. . . | | |  ... .   |   |.. ||  | |.|.| | | | |. |.  .||... ||||| ||. |
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARR

ASEGRAQSHSV-----------GQ-------------LIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQMTCKVSDFGLARTLDGEQY--TTTTTRL
  .  ... |            .|             |. .  |.  || .|.   .||||||||||||      |..||||||      |   ||  ||
PPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRL

PVKWMAPESLGRRIYTTKSDVWAFGVTMWEIFSLGGTPYQEYR-NAHILNLLESGYRLPVPMQMPSKAHGIMQQCWSMEAEERPAFAELIGSF
|.||||||.|  |.||..|||| .|| .|||. .||.||        .  .| .|.|.  | . ..    .| |||  ....|| |..|. ..
PIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase RTKB5.AA KIN6 625-858 38 1.2e-75 249.47 In-house 46-305 (305) Show / Hide 
Range on Protein: 625-858
Range on HMM: 46-305/305
Sequence Identity: 38% (100 aa)

ACAAKRLPPGASYEAHQDFRAELALMKELGTHPNVIGLVGHCFQDEPPILLVELAELGNLRDLLR--KGRASE---------GRAQSH-SVG-------Q
.|| | ||  |   ||.||. | |.|| || || .. . |     ..| |.||. . ..|   ||  .  .           .   .  ...       .
QCAVKMLPSHADEMAHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYCCHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHKD

LIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQM---TCKVSDFGLAR--TLDGEQYTTTTTR-LPVKWMAPESLGRRIYTTKSDVWAFGVTMWEIFS
|  |  || .|| .| .   ||||||||||||. .    |||.|||||.|    |  |||.   | ||.||||||.|    . .||||| ||| |.|.||
LYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFS

LGGTPYQEYR-NAHILNLLESGYRLPVPMQMPSKAHGIMQQCWSMEAEERPAFAELIGSF
||. || |      ..  ..|| |.  |   | .   |||.||.   ..||.| |. . |
LGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase RTKB5.AA Fer 596-859 30 4.4e-73 248.22 In-house 1-283 (283) Show / Hide 
Range on Protein: 596-859
Range on HMM: 1-283/283
Sequence Identity: 30% (89 aa)

LWIGPKLGNGAFGEVFQAW-----IAHQSADG-KQACAAKRL-PPGASYEAHQDFRAELALMKE-LGTHPNVIGLVGHCFQDEPPILLVELAELGNLRDL
  .| |||.||||||...      . . .... | |.. |..   .|. |  ..| .|  .|.  .  ||||. . | | ...|  .. |..  |.|.. 
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYD-HPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSY

LRKGRASEGRAQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQ-QMTCK--VSDFGLARTLDGEQYTTT----TTRLPVKWMAPESLGRRI
|.|  .      . |. ..|..| |. .||..|... .||||.||||.|... .  .|  .||||..|......|. .     ...|..|.|||..  .|
LKKNKNK-----TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGI

YTTKSDVWAFGVTMWEIFSLGGTPYQE----YRNAHI-----LNLLESGYRLPVPMQMPSKAHGIMQ-QCWSMEAEERPAFAELIGSFT
|..|.|||.|||..||||. | .|| .     ... .      .  ..||..| | .||.    ||  ||| .. |.|| ..|..  . 
YSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase RTKB5.AA VEGFR 712-858 46 6.9e-59 201.95 In-house 181-332 (332) Show / Hide 
Range on Protein: 712-858
Range on HMM: 181-332/332
Sequence Identity: 46% (70 aa)

QIVNGMAFLEQNDVIHRDLAARNVLVDQQMTCKVSDFGLART--LDGEQYTTTTT--RLPVKWMAPESLGRRIYTTKSDVWAFGVTMWEIFSLGGTPYQE
|. .|| ||.   .|||||||||.|..   . | .||||||    ..  | . .   ||| |||||||.  ..|||.||||..|| .|||||||| ||  
QVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPG

YR-NAHILNLLESGYRLPVPMQMPSKAHGIMQQCWSMEAEERPAFAELIGSF
   .    | | .|||.  |   .     ||..||. | ||||.|.||   .
VQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase RTKB5.AA S_TKc 596-859 22 6.4e-41 143.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 596-859
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

LWIGPKLGNGAFGEVFQAWIAHQSADGKQACAAKRLPPGASYEAHQDFRAELALMKELGTHPNVIGLVGHCFQDEPPILLVELAEL--GNLRDLLRKGR-
  |. |.| ||||.|....  .     .. .| |...        ...| |....|.   |||.. | ...   .   .  |...   |.|.|...| . 
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------ASEGRAQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQMTCKVSDFGLARTLDGEQYTTTTTRLPVKWMAPESLGRRIYTT-KS
       .| .|..        ...||....... .. .|||||   |.|.|.  . |..|||||| |       ||      .|||| |    |.. |.
HGLRFPFPE-HARF--------YMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKC

DVWAFGVTMWEIFSLGGTPYQEYRNAHILNLLESGYRLPVPMQMPSKAHGIMQQCWSMEAEERPAFAELIG--------SFT
|.|..|....| .. | .|..    . .....            .. |  ....|. .. |.||   |.           . 
DWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKB5.AA Pkinase 596-858 21 6.9e-30 106.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 596-858
Range on HMM: 1-293/293
Sequence Identity: 21% (65 aa)

LWIGPKLGNGAFGEVFQAWIAHQSADGKQACAAKRLPPGASYEAHQDFRA--ELALMKELGTHPNVIGLVGHCFQDEPPILLVELAELG----NLRDLLR
. || |.| |.||.|   ...|   .||. .  .   .... . .|  |   |...||.|  |||.. | . .  .  . .  |..| |     | |...
YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

KGRASEGRAQSHSVGQLIEFCRQIVNGMAFLEQNDVIHRDLAARNVLVDQQMTC----KVSDFGLARTL-DGEQYTTTTTRLPVKWMAPESLG-RRIYTT
    ..|.    |  ... ...||. |.... .. .|||||   |.|.|.....    |..|||||. .    .  .||      .|||| .  .. |..
T--WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KSDVWAFGVTMWEIFSLGGTPYQEY----------RNAHILN-LLESGYRLPVPMQ---------------MPSKAHGIMQQCWSMEAEERPAFAELIGS
|.|.|..|....| .. | .|...           . . |.   |.. .  . ..                ... .  ..  |. .  ..|| ....  .
KVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

--F
  |
PWF
Kinase RTKB5.AA VEGFR 596-692 33 2.8e-09 31.33 In-house 1-101 (332) Show / Hide 
Range on Protein: 596-692
Range on HMM: 1-101/332
Sequence Identity: 33% (34 aa)

LWIGPKLGNGAFGEVFQAW-IAHQSADGKQACAAKRLPPGASYEAHQDFRAELALMKELGTHPNVIGLVGHCF---QDEPPILLVELAELGNLRDLLRKG
| .|  || |||| | .|  .  .   . .  | |.| .||  . |    .|| ... .|.| ||  . | |    |  |    ||    ||| . ||  
LKLGKMLGRGAFGQVHEASAFGIRKMETCTTVAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTK

R
|
R
Kinase RTKB5.AA KIN6 601-611 63 0.047667 2.33 In-house 6-16 (305) Show / Hide 
Range on Protein: 601-611
Range on HMM: 6-16/305
Sequence Identity: 63% (7 aa)

KLGNGAFGEVF
|||.|||. |.
KLGHGAFCNVY