Gene RTKA9 (M.brevicollis)

RTKA9

Species: M.brevicollis
Alias: RTKA9
External Links:
Annotation:

Classification

Group: TK
Family: RTKA

Sequence

Name Sequence Type Origin Length Description Download
RTKA9.AA Protein None 1968 None Fasta, JSON
RTKA9.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of RTKA9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LDLa RTKA9.AA LDLa 402-440 27 2.8e-05 21.37 SMART 1-47 (47) Show / Hide 
Range on Protein: 402-440
Range on HMM: 1-47/47
Sequence Identity: 27% (13 aa)

PCMSPE--ERAAWGGEFIFPTQVCDGVPDCTNGRDE------GGCQA
.| . .  . .   |. |  ..||||..|| .| ||       .|  
TCPPDHPNQFQCGNGRCIPKSWVCDGDNDCGDGSDEWPFFDPENCPQ
Kinase RTKA9.AA RTKA 682-932 43 3.9e-169 568.19 In-house 1-314 (314) Show / Hide 
Range on Protein: 682-932
Range on HMM: 1-314/314
Sequence Identity: 43% (136 aa)

MEVIEVVGSGNFGRVLKAKLFE--DESRKLTSLVAVKEPVDLMLNEVDALSDFLKEAMVLQAIASHPNVVGLHGVCLPNST--VNRHCALVCEYCEFGEL
|.|..|||.|.|..|..|.|..  ||.|.....||.||..|||||....||....|.|.|......|...||||||||...  ...||..|||.|..|.|
MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQCVAIKECDDLMLNDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGNL

KALLVQ--------------QHS-------ALQSVAVQRRVALQMC-------SAMAFLASKGIIHRDLAARNVLVARLQP-ISIRLADFGLSRLVSKDD
.....|              |||       .|.|.|......||||       .|||.||..||.|||.|||||||..||| ....||||||||.....|
RDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKCGIVHRDVAARNVLVMSLQPAFHCKLADFGLSRVMPSSD

YYRSRGKDGLPFRWMAPEAIRELRFSQASDVWSLGVVVWEVLHHGQTPYG------------------------------SLDGHHIVQLLLQGSTLSME
||.||..|..||||||||.|.|.|.|..|||||.||.|||.|.|||||..                              ..|.|||.|.|.||.||.|.
YYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLPMP

PGVDPLLSEFCFWC
|...|.|..|||||
PCCPPCLQRFCFWC
Kinase RTKA9.AA TK 682-950 18 1.1e-87 293.99 In-house 1-486 (486) Show / Hide 
Range on Protein: 682-950
Range on HMM: 1-486/486
Sequence Identity: 18% (90 aa)

MEVIEVVGSGNFG---RVLKAKLFEDE--------------------SRKLTSLVAVKEPVDLMLNEVDALSD-----------FLKEAMVLQAIAS---
 ..... |.|.||   .| |......                     ... .  ||||   .   .. ..  |           ||.||....   .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVGLHGVCLPNSTVN--------RHCALVCEYCEFGE----LKALLVQQH----------------------------------------------
 |||.| |.|||. . ..         ... .| ||.. |     |.  | . .                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----SALQSVAVQRRVALQ-------------------MC----SAMAFLASK------GIIHRDLAARNVLVARLQPIS---------IRLADFG----
    ..... ... .  ||                   ||    ..|..|.||      ...||||||||.||..  ..          ...||||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LSRLVSK------------------------DDYYRSRGKDGLPFRWMAPEAIR---------ELRFSQASDVWSLGVVVWEVLHHG-QTPYGSLD
    |.| . .                        .||||.. .. ||.||||||...         . .|. .|||||.||..||.. .| ...|| ..
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

G---------HHIVQLLLQGST------------LSME--PGVD--------------PLLSEFCFWCWQRAASARPSFADLKDQL
          . ....| .|..            . |.  |.                ... ...  ||.. .. ||.|..|..||
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKA9.AA Pkinase_Tyr 682-950 31 3.8e-77 261.91 Pfam 1-270 (270) Show / Hide 
Range on Protein: 682-950
Range on HMM: 1-270/270
Sequence Identity: 31% (87 aa)

MEVIEVVGSGNFGRVLKAKLFEDESRKLTSLVAVKEPVDLMLNEVDA--LSDFLKEAMVLQAIASHPNVVGLHGVCL----PNSTVNRHCALVCEYCEFG
 . ... |.|.||.| |....  .  . .  ||||          ..  . ||..|| ..  . .|||.| |.|||.    ||     .  .| ||.. |
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-----QIYIVMEYMPHG

ELKALLVQQ--HSALQSVAVQRRVALQMCSAMAFLASKGIIHRDLAARNVLVARLQPISIRLADFGLSRLVSKDDYY-RSRGKDGLPFRWMAPEAIRELR
 |.  | ..       ..      ..| ...|..|.||..|||||||||.||..  .  .. .||||.|.. .|||| |.||.  || .|||||.|.. .
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK

FSQASDVWSLGVVVWEVLHHGQTP-YGSLDGHHIVQLL-LQGSTLSMEPGVDPLLSEFCFWCWQRAASARPSFADLKDQL
|. .||||| ||. ||..  |..| |  .. . .....  .|  . . ..  . . .    ||.  .. ||.|...  ||
FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKA9.AA TyrKc 682-950 30 9.2e-76 258.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 682-950
Range on HMM: 1-280/280
Sequence Identity: 30% (91 aa)

MEVIEVVGSGNFGRVLKAKLFEDESRKLTSLVAVKEPVDLMLNEVDALSDFLKEAMVLQAI-ASHPNVVGLHGVCLPNS----TVNRHCALVCEYCEFGE
 . ... |.|.||.| |...           ||||     ||.|   . ||..|| ..  .  .|||.| |.|||.  .     .  .. .| ||.. | 
ITLGKKLGEGAFGEVYKGTWK--------IQVAVK-----MLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM-IVMEYMPHGD

LKALLVQQHSALQSVAVQRRVALQMCSAMAFLASKGIIHRDLAARNVLVARLQPISIRLADFGLSRLVSKD-------DYYRSR---GKDG-LPFRWMAP
||  |   .    ...     ..| .. |..|.||..|||||||||.||.. .   .. .|||||| .  |       ||||..   |... || |||||
LKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EAIRELRFSQASDVWSLGVVVWEVLHHGQTPYGS-----LDGHHIVQLLLQGSTLSMEPG--------VDPLLSEFCFWCWQRAASARPSFADLKDQL
|.|.. .|. .||||| ||. ||..  ||.||       ..  ...... ||  .   |           . . .   .||.. .. ||.|.......
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKA9.AA UTK 682-900 31 3.2e-64 218.58 In-house 1-244 (296) Show / Hide 
Range on Protein: 682-900
Range on HMM: 1-244/296
Sequence Identity: 31% (78 aa)

MEVIEVVGSGNFGRVLKAKLFEDESRKLTSLVAVKEPVDLMLNEVDALS---DFLKEAM---VLQAIASHPNVVGLHGVCLPNSTVNRHCALVCEYCEFG
 .  .  |.|.|| | ||.. ..  . ....||||. .    .  ..     ||..||    .... . ||||..| |||.  .      ..| ||.| |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ-HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP----WMIVTEYMENG

ELKALLVQQHS------ALQSVAVQRRVALQMCSAMAFLASKGIIHRDLAARNVLVARLQ-----PISIRLADFG---LSRLVS---------KDDYYRS
 | ..|  ..       ....   .   |..  ..|..|.|.|..||||||||.||..         ....||||   .||.|.          ..||..
DLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA

RGKDGLPFRWMAPEAIREL-RFSQASDVWSLGVVVWEVLHHGQTPYGSL
.. | .|.|||||||. .  ||...|||||.|||.||....|..||. .
QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGM
Kinase RTKA9.AA RTKF 682-950 32 6.5e-54 171.94 In-house 1-272 (272) Show / Hide 
Range on Protein: 682-950
Range on HMM: 1-272/272
Sequence Identity: 32% (91 aa)

MEVIEVVGSGNFGRVLKAKLFEDESRKLTSLVAVKEPVDLMLNEVDALSDFLKEAMVLQAIASHPNVVGLHGVCLPNSTVNRHCALVCEYCEFGELKALL
  . |..|.|.||||...    .     .  ||.|   .. .   .  .  |.|.  .  .  || .. ..|. |.        |.| |.   | ..  |
IMLGEQLGHGHFGRVHHGYWRQQKGQ--RQPVAIKHIHTQDMM--NWRRQMLRECCAMNRVGQHPHIIQFFGI-LMTPFEQNEMAFVMEFAPHGDMRRYL

VQQHSALQSVAVQRRVALQ-MCSAMAFLASKGIIHRDLAARNVLVARLQP-ISIRLADFGLSRLVSKD-DYYRSRGKDGLPFRWMAPEAIRELRFSQASD
 |  . |  .|.    | | . .||.|  ..| .|||.|||||||   || . . | |||| |  |   |||||   . |||||||||||   ||.| ||
QQHDVDLG-RAHMLDAAHQVVAEAMVFISRQGLVHRDVAARNVLVFEDQPRMYVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSD

VWSLGVVVWEVLHHGQTPYGSLDGHHIVQLLLQGSTLSMEPGVD------PLLSEFCFWCWQRAASARPSFADLKDQL
||| |.  .|    |  |||      ..|    | || | . .         .   |   |     .||.|  . | |
VWSFGMMLFELFTRGDVPYGNMPHPVVLQFIRRGKTLQMPDSCPPDVCRFVSIHWLCQRIWTFDPEQRPDFDIIEDHL
Kinase RTKA9.AA TK-Unique 682-950 28 1.2e-52 179.81 In-house 1-294 (294) Show / Hide 
Range on Protein: 682-950
Range on HMM: 1-294/294
Sequence Identity: 28% (86 aa)

MEVIEVVGSGNFGRVLKAKLFEDE-SRKLTSLVAVKEPVDLMLNEVDALSD---FLKEAMVLQAIASHPNVVGLHGVCLPNSTVNRHCALVCEYCEFGEL
 || .|.|.|.|| | .......  ..  .. ||||     ||..   . |   ||||. .....  |||.| . |.|  ..  .... .. |||. | |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVK-----MLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD--EPWM-IIMEYCPCGNL

KALLVQQHSALQSV--------------AVQRRV----------ALQMCSAMAFLAS--KGIIHRDLAARNVLVARLQPISIRLADFGLSRLVSKDDYYR
  .| .   |  ..              . .|.           | | ...|..|||  |.|.||||.|||||...     . ..|||..| |...  | 
QHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE--DKVCKICDFGMARDVYTNGVYS

SRGK-DGLPFRWMAPEAIR--ELRF-SQASDVWSLGVVVWEVLHHGQTPYGSLDGHHIVQLLLQGSTLSMEPGV-DPLLSEFCFWCWQRAASARPSFADL
. ..   .| ||||||...  .  . .  |||||.||. ||..  |..||....   |.... .|...   ...  . . ..   |||. .. ||||...
MMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQI

KDQL
|..|
KHRL
Kinase RTKA9.AA FAK 732-955 37 8.1e-50 165.02 In-house 71-285 (285) Show / Hide 
Range on Protein: 732-955
Range on HMM: 71-285/285
Sequence Identity: 37% (84 aa)

FLKEAMVLQAIASHPNVVGLHGVCLPNSTVNRHCALVCEYCEFGELKALLVQQHSALQSVAVQRRVALQMCSAMAFLASKGIIHRDLAARNVLVARLQPI
|..||.... .  || .| | |.|  . .      .. | |..|||.. |  .   | ..|     ..|.| |||.| ||  .||| |||||||.   | 
FMQEAYIMKQFD-HPHIVKLIGICEEMPIW-----IIMELCKYGELRHYLQRNKNSL-KHATLILYCYQLCMAMAYLESKKFVHRDIAARNVLVS--SPD

SIRLADFGLSRLVSKDDYYRSRGKDGLPFRWMAPEAIRELRFSQASDVWSLGVVVWEVLHHGQTPYGSLDGHHIVQLLLQGSTLSMEPGVDPLLSEFCFW
 ..|.||||||... ..||..  |  || .||.|| |   ||  |||||  || .||.| .|  |.  .    ..  . .|  | | |   | |      
CVKLGDFGLSRWMHDHSYYKASPKGKLPIKWMSPESINFRRFTTASDVWMFGVCMWEILMYGVKPFQWVKNNDVIGRIENGERLPMPPNCPPTLYSLMTR

CWQRAASARPSFADLKDQLEAGYI
||    | || | .|| ||.  | 
CWAYDPSKRPRFKELKCQLKDIYQ
Kinase RTKA9.AA RTKE 682-950 28 1.4e-49 167.27 In-house 1-293 (293) Show / Hide 
Range on Protein: 682-950
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

MEVIEVVGSGNFGRVLKAKLFE-------------DESRKLTSLVAVKEPVDLMLNEVDALSDFLKEAMVLQAIASHPNVVGLHGVCLPNSTVNRHCALV
   . . ||| || |  . .                |.   | .||||      | .   ...| ...| .  .  |||||.|..|    ..  .| ..|
LTFMRALGSGEFGEVWLMTMPNHAHSPNYSKETISSEQQRSTRQVAVK-----TLHNHECHHEF-VQEMTMMCKLHHPNVVHLLHV----VQMKQHFMMV

CEYCEFGELKALLVQQHSALQSVAVQRRVALQMCSAMAFLASKGIIHRDLAARNVLVARLQPIS-IRLADFGLSRLV-----SKDDYYRSRGKDGLP---
 || . | |.  | ..|..  |   |.... |  ..|.||.. ||.||||.|.||.. |   .  ...||.|||| .     . . ||| . .  .|   
YEYMPGGQLEDWLQDHHGRPTSHEDQIHCLHQVACGMSFLERLGIVHRDLCAHNVYCCRC--WNDVKVADYGLSRDMYLGQEYMQCYYRIKTRRWMPTTW

--FRWMAPEAIRELRFSQASDVWSLGVVVWEVLHHGQTPYGSLDGHHIVQLLLQGST------------LSMEPGVDPLLSEFCFWCWQRAASARPSFAD
   ||.|||...   || .||||. |. .|||.. || ||  .|.  ..| ..|..             ..  .  .|...    || .... .||.||.
GSRRWWAPEVWKDQHFSFKSDVWAYGCLCWEVWNNGQMPYAHMDDQQFMQRIVQCQMPSGGHLGDHEPVHAPPVHCPPWADRLMQWCLCINPEHRPNFAQ

LKDQL
| ...
LYQMW
Kinase RTKA9.AA RTKD 682-952 32 3.7e-49 165.11 In-house 1-262 (262) Show / Hide 
Range on Protein: 682-952
Range on HMM: 1-262/262
Sequence Identity: 32% (91 aa)

MEVIEVVGSGNFGRVLKAKLFEDESRKLTS-LVAVKEPVDLMLNEVDALSDFLKEAMVLQAIASHPNVVGLHGVCLPNSTVNRHCALVCEYCEFGELKAL
....| .|.||.| | || | |. .  ..  |||||    .     ...  .. ||  . |   |.|.| ||||     |.|   ..| |||| | | | 
IKCLEPIGKGNWGMVFKAMLEEHIMKGIPGFLVAVKI---MKNQSQEQVMEMTREAAFM-AQFNHDNIVRLHGVV----TTNQPHIMVMEYCEHGSLQAY

LVQQ--HSALQSVAVQR-RVALQMCSAMAFLASKGIIHRDLAARNVLVARLQPISIRLADFGLSR--LVSKDDYYRSRGKDGLPFRWMAPEAIRELRFSQ
| .     ..|    .| |.|.    . | |. .|..||| ||||.|.  .      ..||||.|    .   || |.|.   | || |||. .|..|||
LRENGEDMDNQ----HRFRMARDVAMGLAYLHFRGCCHRDIAARNILLDSN--YRAKIGDFGLTRQQANGDSEYYISHGQ-AIPVRWCAPEVLEEHKFSQ

ASDVWSLGVVVWEVLHHGQTPYGSLDGHHIVQLLLQGSTLSMEPGVDPLLSEFCFWCWQRAASARPSFADLKDQLEA
|||||| .|.|.|.   .| ||  .    .    .||  |.   .    . . .  ||    . ||..  . ||.. 
ASDVWSWAVFVYEIWTQAQLPYRDMHNQKVWHYVIQGYRLTRPMQCPRDIWALMMDCWAEDPKERPRMCQVVDQMTK
Kinase RTKA9.AA Ack 682-909 31 2.1e-48 161.4 In-house 1-224 (266) Show / Hide 
Range on Protein: 682-909
Range on HMM: 1-224/266
Sequence Identity: 31% (74 aa)

MEVIEVVGSGNFGRVLKAKLFEDESRKLTSLVAVKEPVDLMLNEVDALSDFLKEAMVLQAIASHPNVVGLHGVCLPNSTVNRHCALVCEYCEFGELKALL
  . |  |.| || | ..      ..  .  ||||   . ...   ...|||.|. .. ..  ||..| |.|| |   ..     .| | .. | |   |
ITLCEKLGDGCFGVVWRGEWTN--PGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLD-HPHLVRLYGVVL---DQPM-LMMVTELAPCGSLLDCL

VQQHS-ALQSVAVQRRVALQMCSAMAFLASKGIIHRDLAARNVLVARLQPISIRLADFGLSR-LVSKDDYYRSRGKD--GLPFRWMAPEAIRELRFSQAS
 .. . |  ....  . ..| ...|..| .|..|||||||||.|...     .  .||||.| |   .||||. ..    .|| |.|||..| ..|| ||
RKHCRTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDD-RKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHAS

DVWSLGVVVWEVLHHGQTPYGSLDGHHIVQLL
|||. ||  ||.   |. |.  . |  | |..
DVWMFGVTLWEMFSYGEEPWAGCNGYQILQKI
Kinase RTKA9.AA CTKA 805-950 34 4.1e-45 149.44 In-house 144-290 (290) Show / Hide 
Range on Protein: 805-950
Range on HMM: 144-290/290
Sequence Identity: 34% (51 aa)

MAFLASKGIIHRDLAARNVLVARLQPISIRLADFGLSRLVSKD-DYYRSRGKDGLPFRWMAPEAIRELRFSQASDVWSLGVVVWEVLHHGQTPYGSLDGH
| .||. |..|||||.||.|. .     | .||||..|. .    || .  .  .|.|||||||... .|| |||||. ||..||..  | .|.  .   
MNYLAEMGFVHRDLACRNCLLGQYC--HIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQ

HIVQLLLQG--STLSMEPGVDPLLSEFCFWCWQRAASARPSFADLKDQL
 ..|. . .  . | . .     |   .  ||. .  .||.|. |.  |
EVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase RTKA9.AA S_TKc 682-955 22 9.1e-42 145.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 682-955
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

MEVIEVVGSGNFGRVLKAKLFEDESRKLTSLVAVKEPVDLMLNEVDALSDFLKEAMVLQAIASHPNVVGLHGVCLPNSTVNRHCALVCEYCEF--GELKA
 |.....|.| ||.| |..  .        .||.|.             ....|  .|.    |||.| |..|.        |  .| |||.   |.|. 
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFD

LLVQQHSAL----QSVAVQRRVALQMCSAMAFLASKGIIHRDLAARNVLVARLQPISIRLADFGLSRLVSKDDYYRSRGKDGLPFRWMAPEAIRELRFSQ
..... .       .  . |... |.|.|.... |.|||||||   |.|. .     | ..||||.|..                 .|||| .    .. 
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGK

-ASDVWSLGVVVWEVLHHGQTPYGSLDGHHIVQLLLQGSTLSMEPGVDPLLSEFCFWCWQRAASARPSFADLKD----QLEAGYI
 ..|.||.|....| |  |..|.   . . . ....           .| . .|   |.|.  . ||.  ..           ..
CKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKA9.AA Pkinase 682-950 20 5.3e-40 142.52 Pfam 1-293 (293) Show / Hide 
Range on Protein: 682-950
Range on HMM: 1-293/293
Sequence Identity: 20% (65 aa)

MEVIEVVGSGNFGRVLKAKLFEDESRKLTSLVAVKEPVDLMLNEVDALSDFLK------EAMVLQAIASHPNVVGLHGVCLPNSTVNRHCALVCEYCEFG
 ......|||.||.| |..   ..      .||||      .. ... |....      |. ... . .|||.| |....      ..|. .| |||| |
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVK-----IIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED----KDHIYMVMEYCEGG

----ELKALLV-QQHSAL-QSVAVQRRVALQMCSAMAFLASKGIIHRDLAARNVLVA-RLQP-ISIRLADFGLSRLVSKDDYYRSRGKDGLP--FRWMAP
    .|....  ..| ..  |  . .....|........ |.|||||||   |.|.  . ..  .....||||.....   | ...  ...    ..|||
LYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAP

EAIR-ELRFSQASDVWSLGVVVWEVLHHGQTPYGSL------DGHHIVQLLLQGSTLSMEPGVD--------------------PLLSEFCFWCWQRAAS
| ||     ....|.||.|....|.|  |..|. .       |  ..... ... . . .|  .                    . . .|. ||...  .
EVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK

ARPSFADLKDQ--L
 ||......    .
KRPTAEQILQHPWF
Kinase RTKA9.AA CTKA 682-756 34 4.8e-09 26.38 In-house 1-79 (290) Show / Hide 
Range on Protein: 682-756
Range on HMM: 1-79/290
Sequence Identity: 34% (28 aa)

MEVIEVVGSGNFGRVLKAKLFEDES-----RKLTSLVAVKEPVDLMLNEVDALS-DFLKEAMVLQ-AIASHPNVVGLHGVCL
  .   .|.| .| | .| |  |       ||   .||||    |  .  ..    || || ||     .||||..| |||.
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKM---LKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCT
Kinase RTKA9.AA Ack 932-950 47 2e-06 17.44 In-house 248-266 (266) Show / Hide 
Range on Protein: 932-950
Range on HMM: 248-266/266
Sequence Identity: 47% (9 aa)

CWQRAASARPSFADLKDQL
|||  .  ||.|....|||
CWQHHPADRPTFSAIRDQL
Kinase RTKA9.AA UTK 932-950 42 1.8e-05 14.69 In-house 278-296 (296) Show / Hide 
Range on Protein: 932-950
Range on HMM: 278-296/296
Sequence Identity: 42% (8 aa)

CWQRAASARPSFADLKDQL
||.   . ||.| || .|.
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