Gene RTKA3 (M.brevicollis)
RTKA3
Species: M.brevicollis
Alias: RTKA3
External Links:
Annotation:
Sequence
Protein domains of RTKA3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LDLa | RTKA3.AA | LDLa | 369-409 | 27 | 2.3e-05 | 22.07 | SMART | 1-47 (47) | Show / Hide |
Range on Protein: 369-409 Range on HMM: 1-47/47 Sequence Identity: 27% (13 aa) FCPKP-AQNVVCPSSGSALEIVQICDGVADCPNGEDE------ASCHG || |. .| . . |||. ||..|.|| . |. TCPPDHPNQFQCG-NGRCIPKSWVCDGDNDCGDGSDEWPFFDPENCPQ |
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| Ldl_recept_a | RTKA3.AA | Ldl_recept_a | 392-407 | 50 | 0.000122 | 16.9 | Pfam | 24-41 (41) | Show / Hide |
Range on Protein: 392-407 Range on HMM: 24-41/41 Sequence Identity: 50% (9 aa) CDGVADCPNGEDE--ASC ||| .|| .|.|| ..| CDGDPDCHDGSDEWPENC |
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| Kinase | RTKA3.AA | RTKA | 644-885 | 52 | 3.1e-182 | 611.69 | In-house | 1-314 (314) | Show / Hide |
Range on Protein: 644-885 Range on HMM: 1-314/314 Sequence Identity: 52% (166 aa) IKVEHAVGHGNFSDVYQASLLRGE----QAPWCVAIKKCH----ADKTTLLAWLREIMLLHSFRDQPNIIGLHGVLLSVAK---LSNLSAVLEWAPHGNL ..|.| ||||.||.||||||...| |.|.|||||.|. .|||||.||.||||||||.||.|.|||||||.|.... |....|.||.||||| MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQCVAIKECDDLMLNDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGNL RDFVRRHP------------------------LSEAQLHQALHQTV-------SALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSSE |||||.|| |||||.||||.|.. .|.|||||..||||||||||||||...|.|.|||.||||||.||||. RDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKCGIVHRDVAARNVLVMSLQPAFHCKLADFGLSRVMPSSD YYKSTADSEMPFRWMALECLVARRYSEHSDVWAFGVLVWELVTAGATPWQ------------------------------GMELPAIIQQLKAGAALPLP ||||.||.||||||||.||...||||||||||.||||||||.|.|.|||| |..|..|||.||.|..||.| YYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLPMP PGAPSIAQRFALPL |..|...|||.. PCCPPCLQRFCFWC |
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| Kinase | RTKA3.AA | TK | 644-875 | 18 | 9.7e-74 | 246.37 | In-house | 1-444 (486) | Show / Hide |
Range on Protein: 644-875
Range on HMM: 1-444/486
Sequence Identity: 18% (83 aa)
IKVEHAVGHGNFS---DVYQASLLR----------------------GEQAPWCVAIKKCHADKTTLLAW------------------LREIMLLHS-FR
|.... |.|.| .||.. . . .|... ||.| .... .. . ..|......
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
DQPNIIGLHGVLLSVAKL---------SNLSAVLEWAPHGN----LRDFVRRH-----------------------------------------------
. |||. |.|| . .. . |.|..|||. |||. |..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
----------PLSEAQLHQ-------------------ALHQTVSALAYLAKLDI------VHRDVAARNVLVMAASP--------TFVCKLGDFG----
||....|.| .| ....||... . ||||.||||.|| . ..|||..|||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ
----LSRIMPS------------------------SEYYKSTADSEMPFRWMALECLV---------ARRYSEHSDVWAFGVLVWELVTAGATPWQG-ME
|.| ..| ..||... . .|.|||| ||| ..... ||||.||||.||..| |..|. | |
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS
L---------PAIIQQLKAG--------------AALPLPPGAP
....|..| .| ||..|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCP
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| Kinase | RTKA3.AA | Pkinase_Tyr | 644-875 | 31 | 1.4e-64 | 219.39 | Pfam | 1-242 (270) | Show / Hide |
Range on Protein: 644-875 Range on HMM: 1-242/270 Sequence Identity: 31% (77 aa) IKVEHAVGHGNFSDVYQASLL-RGEQAPWCVAIKKC--HADKTT--LLAWLREIMLLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPHGNLRDFVRR |. . |.|.| .||.. . ... ||.|.. .|.. . . .||. ..... . |||. |.|| .. . ... |.| .|||.|.|. |. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK H-----PLSEAQLHQALHQTVSALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSSEYY-KSTADSEMPFRWMALECLVARRYSEHSDV | ||. .| | .| ....||. ..|||.||||.|| ..|.| .||||.| . . .|| ... .. .| .|||.||. ..... ||| HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV WAFGVLVWELVTAGATP-WQGMELPAIIQQL-KAGAALPLPPGAP |.|||| ||..| |..| ..|| ..... . | .| |...| WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCP |
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| Kinase | RTKA3.AA | RTKF | 644-882 | 35 | 8.8e-64 | 204.24 | In-house | 1-245 (272) | Show / Hide |
Range on Protein: 644-882 Range on HMM: 1-245/272 Sequence Identity: 35% (87 aa) IKVEHAVGHGNFSDVYQASLLRGEQAPWCVAIKKCHADKTTLLAW----LREIMLLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPHGNLRDFVRRH | .. .|||.| | .. . |||| | . | ||| .. . | || ..|.| .. .. |.| |||| .| . .| IMLGEQLGHGHFGRVHHGYWRQQKGQRQPVAIKHIHT--QDMMNWRRQMLRECCAMNRVGQHPHIIQFFGILMTPFEQNEMAFVMEFAPHGDMRRYLQQH P--LSEAQLHQALHQ-TVSALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSS-EYYKSTADSEMPFRWMALECLVARRYSEHSDVWAF | |.. .| || .|... . |||||||||||| . |. || |||| |. . .|| | . | |||||| | .||... |||| | DVDLGRAHMLDAAHQVVAEAMVFISRQGLVHRDVAARNVLVFEDQPRMYVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWSF GVLVWELVTAGATPWQGMELPAIIQQLKAGAALPLPPGAPSIAQRFA |.. .||.| | |. .|. |...| | | .|. .| ||. GMMLFELFTRGDVPYGNMPHPVVLQFIRRGKTLQMPDSCPPDVCRFV |
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| Kinase | RTKA3.AA | RTKL | 646-875 | 37 | 2.3e-59 | 155.39 | In-house | 3-231 (259) | Show / Hide |
Range on Protein: 646-875 Range on HMM: 3-231/259 Sequence Identity: 37% (90 aa) VEHAVGHGNFSDVYQASLLRGEQAPWCVAIKKCHADKTTL--LAWLREIMLLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPHGNLRDFVRRHPLSE | | |.|| ||||. . . | |||| | . | |.| .||| . |.|| .||. . . . .|| || |||| . | LENELGRGQFSRVYQAR-SCSRMVPTQVAIKIAHEQQSKNQMDAVLYEAVLLHQL-HHPHIIQMHGCTAVPQR---MAMILELAPNGNLREYLRHDDAPS AQLHQA-----LHQTVSALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSS-EYYKSTADSEMPFRWMALECLVARRYSEHSDVWAFGV . |. | | .||||. ..||| |.|||| | |||| |||||| . .|| . ..||||| .| |. |||||||| SSWPQRQRLQWLCQVAQALAYIHQRRMIHRDLASRNVLLV---PMMVCKLSDFGLSRRLQNEQDYYRPQQNDHVPFRWMSPETLNGKPHTMASDVWAFGV LVWELVTAGATPWQGMELPAIIQQLKAGAALPLPPGAP . .| .| | |. .. | .. || | || | | VCYEVIT-GQVPYADTDMPQVVALLKNEGRLALPAGTP |
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| Kinase | RTKA3.AA | UTK | 644-875 | 28 | 3.4e-57 | 194.23 | In-house | 1-268 (296) | Show / Hide |
Range on Protein: 644-875 Range on HMM: 1-268/296 Sequence Identity: 28% (78 aa) IKVEHAVGHGNFSDVYQASLLR-GEQAPW-CVAIKKCH--ADKTTLLA----WLREIM---LLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPHGNL .. |.|.| .|. |.. . |... ||.|.| ||... . ...| .. |. ||...| || . . . . |.| .. |.| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGV---CTQEEPWMIVTEYMENGDL RDFVRRHPL---------SEAQLHQALHQTVSALAYLAKLDIVHRDVAARNVLVMAAS----PTFVCKLGDFG---LSRIMP---------SSEYYKSTA |...|||. .. |. . . ....||. .||||.||||.|| . . |||..||| .|| .. .|.||... RSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH DSEMPFRWMALECLVAR-RYSEHSDVWAFGVLVWELVTAGATPWQGMELPAIIQQLKAG--AALPLPPGAP . ..|.|||| |.|. . |....||||.|||..||..| |..|. || .....|. .| . .| |.. | QDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCP |
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| Kinase | RTKA3.AA | TyrKc | 644-881 | 27 | 5.5e-53 | 183.26 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 644-881 Range on HMM: 1-280/280 Sequence Identity: 27% (81 aa) IKVEHAVGHGNFSDVYQASLLRGEQAPWCVAIKKCHADKTTLLAWLREIMLLHSF-RDQPNIIGLHGVLLSV----AKLSNLSAVLEWAPHGNLRDFVRR |. .. |.|.| ||.. . ||.|....|. . . .||. ..... . |||. |.|| .. | |.| .|||.|.|. |. ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK HP--LSEAQLHQALHQTVSALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSS-------EYYKSTA--DSE--MPFRWMALECLVARR | |. ..|.. .| . .||.. ..||| ||||.|| . ...| .|||||| . .||... .. .| ||||.||. .. HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLV---GENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YSEHSDVWAFGVLVWELVTAGATPWQG-----MELPAIIQQLKAGAALPLPPG--------APS----------------------IAQRF ... ||||.|||. ||. | |..|. | |. .|...|.| .| || .|. | ..| FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | RTKA3.AA | TK-Unique | 644-873 | 29 | 1.5e-49 | 169.0 | In-house | 1-263 (294) | Show / Hide |
Range on Protein: 644-873
Range on HMM: 1-263/294
Sequence Identity: 29% (79 aa)
IKVEHAVGHGNFSDVYQASLLRGE---QAPWCVAIKKCH--ADKTTLLAWLREIMLLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPHGNLRDFVR-
..|. .| |.|. |. . . .. .. |||.|... |..|. . |.|| .. . |.|||. . |. .. . . ..|..| |||... |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGC--CTKSDEPWMIIMEYCPCGNLQHYLRT
------RH--------------------PLSEAQLHQALHQTVSALAYLAK--LDIVHRDVAARNVLVMAASPTFVCKLGDFGLSR-IMPSSEYYKSTAD
.| |.|. .| . . | ....|||. |||||..|||||. .|||..|||..| .. .| ...
CRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE---DKVCKICDFGMARDVYTNGVYSMMCSQ
SEMPFRWMALECLV--ARRY-SEHSDVWAFGVLVWELVTAGATPWQGMELPAIIQQLKAGAALPLPPG
...| ||||.| | . | .. ||||.|||| ||..| ||.| || . |......| .|.|..
GRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEH
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| Kinase | RTKA3.AA | FAK | 644-875 | 32 | 3.4e-41 | 135.7 | In-house | 1-252 (285) | Show / Hide |
Range on Protein: 644-875
Range on HMM: 1-252/285
Sequence Identity: 32% (85 aa)
IKVEHAVGHGNFSDVYQASLLRGEQ------------------------APWCVAIKKCHADKTTLLA--WLREIMLLHSFRDQPNIIGLHGVLLSVAKL
|. .| | | |||| . .. |||| | .. . . | . .. | | | |. | |. .
ITLNRCIGEGQFGDVYQGVYTNHKNGKGKNLAGNGKNSNSDQRNADSRPDKIQVAIKTCKKCCDDDNKEKFMQEAYIMKQF-DHPHIVKLIGIC----EE
SNLSAVLEWAPHGNLRDFVRRH--PLSEAQLHQALHQTVSALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSSEYYKSTADSEMPFRW
..| .. | || . .|. |. | | | |.||| ||||.||||||| .||. | ||||||||| | ..|||.. .| .|
MPIWIIMELCKYGELRHYLQRNKNSLKHATLILYCYQLCMAMAYLESKKFVHRDIAARNVLV--SSPDCV-KLGDFGLSRWMHDHSYYKASPKGKLPIKW
MALECLVARRYSEHSDVWAFGVLVWELVTAGATPWQGMELPAIIQQLKAGAALPLPPGAP
|. | ||. |||| ||| .|| | | |... .| .. | ||.|| |
MSPESINFRRFTTASDVWMFGVCMWEILMYGVKPFQWVKNNDVIGRIENGERLPMPPNCP
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| Kinase | RTKA3.AA | CTKA | 759-877 | 38 | 4.8e-41 | 135.58 | In-house | 146-264 (290) | Show / Hide |
Range on Protein: 759-877 Range on HMM: 146-264/290 Sequence Identity: 38% (47 aa) YLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSS-EYYKSTADSEMPFRWMALECLVARRYSEHSDVWAFGVLVWELVTAGATPWQGMELPA ||| ...|||| |.||.|. . |. |||..| . || . . ||.|||| | | ..| |||||||||.||. . | .|| .| YLAEMGFVHRDLACRNCLLGQYC---HIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQE IIQQLKAG--AALPLPPGAPSI . | .. .||.|. .|.. VCQAYTSHGMRRLPVPRNCPQV |
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| Kinase | RTKA3.AA | EGFR | 644-872 | 35 | 2.9e-40 | 131.28 | In-house | 1-226 (258) | Show / Hide |
Range on Protein: 644-872 Range on HMM: 1-226/258 Sequence Identity: 35% (83 aa) IKVEHAVGHGNFSDVYQASLL-RGEQAPWCVAIKKC--HADKTTLLAWLREIMLLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPHGNLRDFVRRH- .| | | | || ||. |||| . .. . |.| . . | | |... | || .. |.. | |.|.| |.|| | LKKVKVLGSGAFGTVYKGIWIPEGENVKIPVAIKVLREQTGPKANEEMLDEAYVMASV-DHPHLVRLLGVCMH----SQMQLVTQYMPYGCLLDYVRQHK -PLSEAQLHQALHQTVSALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSSEYYKSTADSEMPFRWMALECLVARRYSEHSDVWAFGVL . .| | . . || . .|||| ||||||| || | | ||||...... | .. || .||||||. |.| ||||..|| DNIGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVK--SPNHV-KITDFGLAKLLEHDEKEYHAQGGKMPIKWMALECIHHRCYTHQSDVWSYGVT VWELVTAGATPWQGMELPAIIQQLKAGAALPLPP .|||.| |. |..|... | . |. | || || CWELMTFGQKPYDGIPAREIPDLLEKGERLPQPP |
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| Kinase | RTKA3.AA | Abl | 644-875 | 32 | 3.4e-38 | 124.7 | In-house | 1-224 (252) | Show / Hide |
Range on Protein: 644-875 Range on HMM: 1-224/252 Sequence Identity: 32% (77 aa) IKVEHAVGHGNFSDVYQASLLRGEQAPWCVAIKKCHADKTTLLAWLREIMLLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPHGNLRDFVR---RHP | ..| .| | . .||.. | .. ||.| . | . .|.| .. . ||.. | || . . . |. ..||| |..| |. IMMKHKLGGGQYGEVYEGVWKRHDC---TVAVKTLKEDTMEVHEFLKEAAIMKEMK-HPNLVQLLGV---CTREPPFYIITEFMCYGNLLDYLRECDREE LSEAQLHQALHQTVSALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSSEYYKSTADSEMPFRWMALECLVARRYSEHSDVWAFGVLVW |. | . | |.. || | . .|||.|||| || . |. ||||.|.| . | | | .| | | | ..| |||||||||.| LPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHH---IVKVADFGLARMM-KDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLW ELVTAGATPWQGMELPAIIQQLKAGAALPLPPGAP |. | | .|. |..| . ..| | . |.| | EIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCP |
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| Kinase | RTKA3.AA | S_TKc | 644-886 | 20 | 9.4e-28 | 99.44 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 644-886
Range on HMM: 1-231/231
Sequence Identity: 20% (55 aa)
IKVEHAVGHGNFSDVYQASLLRGEQAPWCVAIKKCHADKTTLLAWLREIMLLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPH--GNLRDFVRRHP-
.. .|.| |. ||.. . ||||. . .||| .|.. . |||. |..| . ..| |.| ... |.|.|. ....
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGR
------LSEAQLHQALHQTVSALAYLAKLDIVHRDVAARNVLVMAASPTFVCKLGDFGLSRIMPSSEYYKSTADSEMPFRWMALECLVARRYSE-HSDVW
..| . ..|...||.|. .. |.|||. |.|. . |..||||.|.. .|| | | |. .|.|
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWW
AFGVLVWELVTAGATPWQGMELPAIIQQLKAGAALPLPPGA--------------PSIAQRFA-------LPLR
..|....|... | .|.. .. ....... |.. |.. . .. |
SCGCILYEMLC-GYPPFP--QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | RTKA3.AA | Pkinase | 644-852 | 20 | 1e-24 | 88.47 | Pfam | 1-214 (293) | Show / Hide |
Range on Protein: 644-852 Range on HMM: 1-214/293 Sequence Identity: 20% (48 aa) IKVEHAVGHGNFSDVYQASLLRGEQAPWCVAIKKCHADKTTLLAW---LR--EIMLLHSFRDQPNIIGLHGVLLSVAKLSNLSAVLEWAPHG----NLRD .... .| |.|. ||.. .. ||.|. ... . .| || ..... . |||. |... . ... |.|....| | | YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFD FVR---RHPL--SEAQLHQALHQTVSALAYLAKLDIVHRDVAARNVLVMAASPTFVC----KLGDFGLSR---IMPSSEYYKSTADSEMPFRWMALECLV ... . .. || .. . |....|.|. . |.|||. |.|. . .. |..||||.. . ..| .. . .. .|| | . YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID---NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW----YMAPEVIR -ARRYSEHSDVWAFGVLVWELVTAGATPWQG .. |. .|.|..|....|... | .|..| GGQYYGPKVDMWSCGCILYEMLC-GRPPFPG |
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