Gene HMTK08 (M.brevicollis)

HMTK08

Species: M.brevicollis
Alias: HMTK08
External Links:
Annotation:

Classification

Group: TK
Family: HMTK

Sequence

Name Sequence Type Origin Length Description Download
HMTK08.AA Protein None 755 None Fasta, JSON
HMTK08.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of HMTK08.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PTB HMTK08.AA PTB 186-322 12 6.3e-05 19.01 SMART 1-156 (156) Show / Hide 
Range on Protein: 186-322
Range on HMM: 1-156/156
Sequence Identity: 12% (20 aa)

ERLIGTELGTFLGSRPVSKKT-------GNAACEAAVMALRRKNKNRNKGLLATIAVHSDSISYAETMSDDILFEGHIKDVTFVTVLD---------EGQ
.     .. ..||. .|....       |...|...   .|   . . ..   .. . .| ..     . ... . .|. ..|. . .          . 
PWGCCFNV-WYLGCVEVPHHRNSMAPGKGMQVCQECMRKIR---QHWKHWQKMHLHISVDGVKLIDPQTKQVIHHHPIHRISFCAHDPYRWNTGGHHCCD

PEEIFAFIESDDRLD-------TITCHLFLCEKGYADKICTFVSRALQQMRELQERKADD
 . .|..|  ..  .          ||.|.||.  |. |.  . .| |.  ... ..  .
DDRCFGYICRHPNDRGSHRMTYWFRCHVFWCEDPHAEDIAQTIGQAFQVCYQQCQKQRCQ
Kinase HMTK08.AA HMTK 350-612 48 1.1e-185 623.11 In-house 1-291 (291) Show / Hide 
Range on Protein: 350-612
Range on HMM: 1-291/291
Sequence Identity: 48% (140 aa)

LSALKVLGAGQFG-----------------TVYMATLA------QDDADEDQTVAVKMLRTESSNADADEFRYECEVMVQLQHTNVVKLVGVCFEHRPWL
|.|.||.||||||                 .||.|...      .||.......||||||...|..|..||..|.|||.||.|.|.|.|||||...||||
LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKDGDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQLRHPNLVQLVGVCMQQRPWL

CVLEIMPYGDLRKVLQTCASKNLHLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQTQKFRLTGHL-RLAVRWMA
||||.|.|||||.||.||..||..||..|.|.|..|...||.|||||..|||||||||.|.|.||..||||||.....||......|..|. .|...|||
CVLEYMQYGDLRNVLKTCREKNIQLTYHEQLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKHMVKLPIKWMA

PETLGGKRIYFSEKTDVYSFGVFMWEVFESGELPFG--HLKSRAARDEIRAG--LILSQPDDCPDDVFDFMLQAWHKEPEQRPSFSTFHDA
||...|||..||||.||..|||.|||....||.|..  ..|........|.|  |....|||||||..|.| ..|||.|.|||.|.    .
PEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM
Kinase HMTK08.AA TK 350-613 22 3.9e-100 336.42 In-house 1-486 (486) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-486/486
Sequence Identity: 22% (111 aa)

LSALKVLGAGQFG---TVYMATLAQDD---------------------ADEDQTVAVKMLRTESSNADADEFRY-------------ECEVMVQLQ----
.  .|.||.||||   .||.... ...                      .. ..||||||. .........| .             |.|.| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HTNVVKLVGVCFEH------------RPWLCVLEIMPYGD----LRKVLQTCASKNLH-----------------------------------------
 | |.|.|.|||...            .||..|.| ||.||    ||. |..|  |  |                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTLVERLNFIKQTLAGMEYIASQ------GFVHMDLAARNVLLGENNL-----------TKIADFGIA-
                               ||. ..| .  |  .||||..|.      .|||.||||||.|.||||             |||||| . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------HKVDPQTQKFRLTG-----------------------HLRLAVRWMAPETLGGK-------RIYFSEKTDVYSFGVFMWEVFESG-ELPFGHL
        .... .   | ..                         .| .||||||.| ..          |..|.||.||||.|||.|  | | . | .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

KS---------RAARDEIRAG--------------LILSQPDDCP--------------DDVFDFMLQAWHKEPEQRPSFSTFHDAI
 .         .   . .|.|              . . ||..||              ....|.|.| ||..||.||.||. |...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase HMTK08.AA TyrKc 350-613 33 9.2e-91 308.76 SMART 1-280 (280) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-280/280
Sequence Identity: 33% (99 aa)

LSALKVLGAGQFGTVYMATLAQDDADEDQTVAVKMLRTESSNADADEFRYECEVMVQL--QHTNVVKLVGVCFEH-------RPWLCVLEIMPYGDLRKV
.. .|.|| |.||.|| .|.        ..||||||. ..      .|. | ..| .|  .| |.|.|.||| ..        | . |.| ||.|||.. 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LQTCASKNLHLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQ--------TQKFRLTGHLR--LAVRWMAPETLG
|. .  |   |.. . |.|  |  .||||..|....| ||||||.|.|||.  ||.||| . ...          . . . ... .  | .||||||.. 
LRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

GKRIYFSEKTDVYSFGVFMWEVFESGELPFGH-----LKSRAARDEIRAGLILSQPDD--------CPDDVFDFMLQAWHKEPEQRPSFSTFHDAI
 .   |..|.||.|||| |||.|  |. |        .. . ..  ...|  . ||..        |||.... |.| || .||.||.||. |. .
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase HMTK08.AA Pkinase_Tyr 350-613 38 1.9e-89 303.54 Pfam 1-270 (270) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-270/270
Sequence Identity: 38% (104 aa)

LSALKVLGAGQFGTVYMATLAQDDADEDQTVAVKMLRTESSNAD--ADEFRYECEVMVQL-QHTNVVKLVGVCF-EHRP--WLCVLEIMPYGDLRKVLQT
.. .|.||.|.||.||..|.  |. .....||||||.  ..  .   ..|  | ..| || .| |.|.|.|||  . .|  .. |.| ||.|||.. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

CASKNLHLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKV-DPQTQKFRLTGHLRLAVRWMAPETLGGKRIYFSEKTDV
  . . .||. . |..  |  .|||| .|....| ||||||.|..|||  ||.||| |  . .  .  .| .|. .| ..||||| .  ..  |..|.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK--FTTKSDV

YSFGVFMWEVFESGELP-FGHLKSRAARDEI-RAGLILSQPDDCPDDVFDFMLQAWHKEPEQRPSFSTFHDAI
.|||| |||.|  || | .  ..     . | . |  . .|..|||.. | |.| ||..||.||.||  |  .
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase HMTK08.AA UTK 350-613 31 1.8e-86 293.62 In-house 1-296 (296) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-296/296
Sequence Identity: 31% (95 aa)

LSALKVLGAGQFGTVYMATLAQDD-ADEDQTVAVKMLRTESS-NADAD---EFRYECE---VMVQLQ-HTNVVKLVGVCFEHRPWLCVLEIMPYGDLRKV
.  .. ||.|.||.|..|.. |..   ... |||| ...... . . .   .|..|.    .| |.. | ||..|||||.   ||. |.| |. ||||..
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LQTCAS----KNLHLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGEN-------NLTKIADFG---IAHKVDP--------QTQKFRLTGHLR
|....       ..||| .|| .  .  .||.|..|.|||| ||||||.|....       .. ||||||    .. |          ... .. ..  |
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LAVRWMAPETLGGKRIYFSEKTDVYSFGVFMWEVFESGELPFGHLKSRAARDEIRAG--LILSQPDDCPDDVFDFMLQAWHKEPEQRPSFSTFHDAI
...|||||| |      |..|.||.||||..||..  | ||....  ...  ....|  . . .|.|||..|.. |.. ||..|. ||.| .  ...
WPIRWMAPEALTHHT-RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase HMTK08.AA TK-Unique 350-613 33 1.7e-77 263.76 In-house 1-294 (294) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-294/294
Sequence Identity: 33% (98 aa)

LSALKVLGAGQFGTVYMATLAQDD--ADEDQTVAVKMLRTESSNADADEFRYECEVMVQLQ-HTNVVKLVGVCFEHR-PWLCVLEIMPYGDLRKVLQTCA
|  ..|.| |.||.|. ... ...   |... ||||||. ...  | ..|  | ..| .|  | |.|...|.| .   ||. ..| .|.|.|.. |.||.
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

SK--------NLH--------------LTLVERLNFIKQTLAGMEYIAS--QGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQTQKFRLTGHLRLAV
 .        ||               ...   ..|..|   ||||.||  ...||.||.||||||.|..  ||.|||.| .|.  ..  . ..  |. .
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMAPETLG-GKRIYFSEKTDVYSFGVFMWEVFESGELPFGHLKSRAARDEIRAGLILSQPDDC-PDDVFDFMLQAWHKEPEQRPSFSTFHDAI
|||||| |   ...|...|.||.||||.|||.|  |. |.. ....  ...||.| .. ||. | ..... .| . |..|||.||||..  . .
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase HMTK08.AA CTKA 350-613 32 1.4e-71 239.78 In-house 1-290 (290) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-290/290
Sequence Identity: 32% (95 aa)

LSALKVLGAGQFGTVYMATLAQDDA------DEDQTVAVKMLRTESSNADADEFRYECEVMV--QLQHTNVVKLVGVCFEHRPWLCVLEIMPYGDLRKVL
.     .| |..| |. | |  |           . ||||||. .   .|. .|  |  |    .. | ||. |.|||  | ||. . | |.||||. .|
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYL

QTCASKN------------------LHLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQTQKFRLTGHLRLAVRW
. |..                    . .   |      |  |||.| |. |||| |||.||.|||  .  |||||| .   .   | . .    .. |||
RACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRW

MAPETLGGKRIYFSEKTDVYSFGVFMWEVFESGELPFGHLKSRAARDEIRAG--LILSQPDDCPDDVFDFMLQAWHKEPEQRPSFSTFHDAI
||||.|  .   ||   ||..||| .||..  ||.|. |.  .     . ..    |  |  ||. .   |   |  || |||.| |     
MAPEAL--CFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase HMTK08.AA Trk 350-613 38 2.9e-65 220.2 In-house 1-275 (275) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-275/275
Sequence Identity: 38% (108 aa)

LSALKVLGAGQFGTVYMATLAQDDADEDQT-VAVKMLRTESSNADADEFRYECEVMVQLQHTNVVKLVGVCFEHRPWLCVLEIMPYGDLRKVLQ------
.   . || | || |..|   .   ..|.. |||| |.  | ||  | |. | |.. .||| ..||. ||| .|.| | | | |  |||.| |.      
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASENARKD-FQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

TCASKNLH------LTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQTQKFRLTGHLRLAVRWMAPETLGGKRIYF
 |  ..        ||. . |  .||  .|| |.||| ||| |.|.|| | |.| . ||.|||    |   |  .|. .|  | .||| ||    ..  |
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRK--F

SEKTDVYSFGVFMWEVFESGELPFGHLKSRAARDEIRAGLI-LSQPDDCPDDVFDFMLQAWHKEPEQRPSFSTFHDAI
.   || |||| |||.|. |  |.  |    . . | .|   | .|  || .|.| ||  |..||.|| .    ||.|
TYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase HMTK08.AA Fer 350-614 29 4.7e-63 213.57 In-house 1-283 (283) Show / Hide 
Range on Protein: 350-614
Range on HMM: 1-283/283
Sequence Identity: 29% (85 aa)

LSALKVLGAGQFGTVYMAT-----LAQDDAD-EDQTVAVKMLRTESSNAD-ADEFRYECEVMVQ-LQHTNVVKLVGVCFEHRPWLCVLEIMPYGDLRKVL
    |.|| | ||.|| ..     . .  .. ..  |.||....|.....   ||  |  .| . ..| ||||. |||    | . |.| .. |.|.. |
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

QTCASKNLHLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTK---IADFGIAHKVDPQTQKFRLT-GHLRLAVRWMAPETLGGKRIYFS
..  .|   ... |..... |  .||||. |.. .| |.||||.|...... |   |.||| . . .  . . ..   . .. .||.||||.  ..| .|
KKNKNK--TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETW-QTGI-YS

EKTDVYSFGVFMWEVFESGELPFGH------LKSR--AARDE-IRAGLILSQPDDCPDDVFDFML-QAWHKEPEQRPSFSTFHDAIS
.||||.|||| .||.|. |. |..       ..     ||   |..|  .  |. .|...  .|. | |.|.||.||......  . 
PKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase HMTK08.AA Src 350-613 32 1.8e-60 204.16 In-house 1-255 (255) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-255/255
Sequence Identity: 32% (87 aa)

LSALKVLGAGQFGTVYMATLAQDDADEDQTVAVKMLRTESSNADADEFRYECEVMVQLQHTNVVKLVGVCFEHRPWLCVLEIMPYGDLRKVLQTCASKNL
.  .. ||.|||| |.|..      .    |||| |.  .   . . |  | ..| .|.| ..|.|  || .  | . | | |  | | . |.   ..  
IKLCRKLGQGQFGEVWMGYW-----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-DGEGR

HLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQTQKFRLTGHLRLAVRWMAPETLGGKRIYFSEKTDVYSFGVFM
|| | . . .  |  .||.|. |. ..| |||||||| ||||. |.|||| |  ..            .. ..|.||| .   .  |. |.|| |||. .
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAI--NYGRFTIKSDVWSFGILL

WEVFESGELPFGHLKSRAARDEIRAGLILSQPDDCPDDVFD-FMLQAWHKEPEQRPSFSTFHDAI
.|..  |  |    . . . ... .|  . .|. ||| ...  ||| |||.||||| | . ..  
TEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase HMTK08.AA Abl 350-613 33 1.8e-57 190.09 In-house 1-252 (252) Show / Hide 
Range on Protein: 350-613
Range on HMM: 1-252/252
Sequence Identity: 33% (89 aa)

LSALKVLGAGQFGTVYMATLAQDDADEDQTVAVKMLRTESSNADADEFRYECEVMVQLQHTNVVKLVGVCFEHRPWLCVLEIMPYGDLRKVLQTCASKNL
..  . || ||.| || .   .     |.||||| |. .  . . .||  |  .| ...| |.|.|.|||    |.  . | |.|| |   |  |  .  
IMMKHKLGGGQYGEVYEGVWKR----HDCTVAVKTLKED--TMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDRE--

HLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQTQKFRLTGHLRLAVRWMAPETLGGKRIYFSEKTDVYSFGVFM
.|. |  |    |   ||.|. .. |.| |||||| |.||... |.||||.|  .  .|  .      .  ..| ||| |  ..  || | ||. ||| .
ELPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDT--YTAHAGAKFPIKWTAPESLAYNK--FSSKSDVWAFGVLL

WEVFESGELPFGHLKSRAARDEIRAGLILSQPDDCPDDVFDFMLQAWHKEPEQRPSFSTFHDAI
||.   |  |.  .      . .  |  . .|. ||..|.. |.| |. ..  ||||   | |.
WEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase HMTK08.AA Frk 350-617 31 1.8e-56 193.93 In-house 1-260 (260) Show / Hide 
Range on Protein: 350-617
Range on HMM: 1-260/260
Sequence Identity: 31% (84 aa)

LSALKVLGAGQFGTVYMATLAQDDADEDQTVAVKMLRTESSNADADEFRYECEVMVQLQHTNVVKLVGVCFEHRPWLCVLEIMPYGDLRKVLQTCASKNL
.  .. ||.|||| |.         .    |||| |.. .  .| ..|  |  .| .|.|. ...|  ||    | . . |.|  | | . ||. . |  
IQLIRRLGSGQFGEVWEGLW-----NNTTPVAVKTLKPGT--MDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGR

HLTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQTQ-KFRLTGHLRLAVRWMAPETLGGKRIYFSEKTDVYSFGVF
.. . . ..   |  ||| |. || ..| ||||||||.||.|  ||||||.|  .  . .  .      |. ..| |||    ..  |. | ||.|||. 
QCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNK--FTIKSDVWSFGIL

MWEVFESGELPFGHLKSRAARDEIRAGLILSQPDDCPDDVFDFMLQAWHKEPEQRPSFSTFHDAISNIY
. |.   | .|.  .  .   . . .|  . || .||  ... ||. ||..|..|| | | .  . . .
LTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase HMTK08.AA S_TKc 350-618 22 2.9e-43 150.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 350-618
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

LSALKVLGAGQFGTVYMATLAQDDADEDQTVAVKMLRTESSNADADEFRYECEVMVQLQHTNVVKLVGVCFEHRPWLCVLEIMPY--GDLRKVLQTCASK
   |...| | ||.|| ..        .. ||.|...        . .| | ... . .| |.||| .|. .      |.| ..   |||..... . ..
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

NLH--LTLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLTKIADFGIAHKVDPQTQKFRLTGHLRLAVRWMAPETLGGKRIYFSE-KTDVYS
 |.  ..  .   ...|.. ..||. |.|..| ||   |.|| |    ||.|||.| ..           ..     .|||| |      ..  | |..|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL-----GYGKCKCDWWS

FGVFMWEVFESGELPFGHLKSRAARDEIRAGLILSQPDDCPDDVFDFMLQAWHKEPEQRPSFSTFHD----AISNIYA
.|. ..| .  |. ||      .  . |.           .... ||. . ..|.||.||.          . .  . 
CGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase HMTK08.AA Pkinase 350-606 22 4.4e-40 142.81 Pfam 1-284 (293) Show / Hide 
Range on Protein: 350-606
Range on HMM: 1-284/293
Sequence Identity: 22% (66 aa)

LSALKVLGAGQFGTVYMATLAQDDADEDQTVAVKMLRTESSNADADEFRY-----ECEVMVQLQHTNVVKLVGVCFEHRPWLC-VLEIMPYG----DLRK
.  ....|.| ||.|| ..   .      .|||| .. .  ... .. ..     |...|  |.| |.|.| ... . ..... |.| .. |    ||  
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFD

VLQTCASKNLHL--TLVERLNFIKQTLAGMEYIASQGFVHMDLAARNVLLGENNLT----KIADFGIAHKVDPQTQKFRLTGHLRLAVRWMAPETLGGKR
...|  ...  .  .  |  ....|.| |.||. |.|..| ||   |.|. .|. .    ||.|||.| ..|  . . . . ..    ..|||| .  ..
YIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIR-GG

IYFSEKTDVYSFGVFMWEVFESGELPFGHL-------KSRAARDEIRAGLILSQPDDCP-------------------DDVFDFMLQAWHKEPEQRPSF
 | . | |..|.|. ..|..  |..|| .        .    .   .. |  . | .|.                   ..  ||.   ..| |..||..
QYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA