Gene HMTK06 (M.brevicollis)

HMTK06

Species: M.brevicollis
Alias: HMTK06
External Links:
Annotation:

Classification

Group: TK
Family: HMTK

Sequence

Name Sequence Type Origin Length Description Download
HMTK06.AA Protein None 1030 None Fasta, JSON
HMTK06.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of HMTK06.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PTB HMTK06.AA PTB 535-681 14 0.000102 16.37 SMART 1-156 (156) Show / Hide 
Range on Protein: 535-681
Range on HMM: 1-156/156
Sequence Identity: 14% (25 aa)

QPFWLSHVYYVGTINAADHS-------GQNTVEHAMGLLADQVRGKPTKFKDLAATDGHRVCLVFSAEGVRVVDAATKELLFNTLVKAVSFHCTTK----
..     | |.|..  . |.       | . .. .|  ..                .. .. |  |  ||...|. ||... .  .. .||    .    
PWGCCFNVWYLGCVEVPHHRNSMAPGKGMQVCQECMRKIR------------QHWKHWQKMHLHISVDGVKLIDPQTKQVIHHHPIHRISFCAHDPYRWN

------LKKGDAFAYIEVDDRRS-------DNECHVFVCQRSPKNQADQLTEAMNKTVQIGKDRVGNPFRA
       .  . |.||  ..  .        ..|||| |. .    |... ... .  |   ..  .  ..
TGGHHCCDDDRCFGYICRHPNDRGSHRMTYWFRCHVFWCEDPH---AEDIAQTIGQAFQVCYQQCQKQRCQ
PID HMTK06.AA PID 584-664 24 0.000213 17.23 Pfam 55-139 (153) Show / Hide 
Range on Protein: 584-664
Range on HMM: 55-139/153
Sequence Identity: 24% (21 aa)

DGHRVCLVFSAEGVRVVDAAT---KELLFNTLVKAVSFHCT-TKLK-KGDAFAY-IEVDDRRSDNECHVFVCQRSPKNQADQLTEAM
.. .. |  | .||...|..|   .|.. .  .. .||       .   ..||| |  |.. .   ||||.|.    .|| ......
HWQKIDLHISTDGVKWIDEKTEAEQECMHDHPMRNISFCADGGDPHVDMRYFAYDICRDGPCQRFACHVFWCCKT--QQAQDIAQTV
Kinase HMTK06.AA HMTK 704-968 53 5.9e-196 657.29 In-house 1-291 (291) Show / Hide 
Range on Protein: 704-968
Range on HMM: 1-291/291
Sequence Identity: 53% (156 aa)

LKAVKAIGAGQFG-----------------KVYLSEYS---VDGAEVEGEPELRAVKMLRGQASDNDRDEFLREAETMLQIGAHENLVSLCGVVLNKRPM
|||.|.|||||||                 ||||.|.|   .||......|..||||||||.||..||.|||||||.|.|. .|.|||.|.||....||.
LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKDGDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQL-RHPNLVQLVGVCMQQRPW

LMVLEYCQYGDLSDVLRSLRRKNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQKNYYKQQGVM-KLSIRWL
|.||||.|||||..||...|.|||.|...|||....|.||||.||||...|||||||||||.|.|....||||||||..|....|......| ||.|.|.
LCVLEYMQYGDLRNVLKTCREKNIQLTYHEQLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKHMVKLPIKWM

AIDAFQ--YKIFSEKSDVWSFAVTVWEILAYGRQPYH--GTELKQVMKAVIAGRRLSQPKE--CPDDVWDMLYSCWIKEPNRRPTFRQLKKA
|..|..  .||||||||||.|.||.|||..||.|||.  ....|.|...|..||||.||..  ||||.||....||.|.|..||||.||.|.
APEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM
Kinase HMTK06.AA TyrKc 704-969 36 8.20000000001e-107 362.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-280/280
Sequence Identity: 36% (108 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLRGQASDNDRDEFLREAETMLQIG-AHENLVSLCGVVLNK-------RPMLMVLEYCQYGDL
..  | .| |.||.||. ...          .  |||||.  |    | .|.|||. | ..|  |.|.| | ||.. .        |...|.||. .|||
ITLGKKLGEGAFGEVYKGTWK----------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

SDVLRSLRRKNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQ------KNYYKQQG--VMK--LSIRWLAID
 | ||. |.|   |.. . |... | |.||.|..||...| ||||||||.| |  ..|.||||.| ...       | ||....    |  | |||.|. 
KDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

AFQYKIFSEKSDVWSFAVTVWEILAYGRQPYHG-----TELKQVMKAVIAGRRLSQPKE--------CPDDVWDMLYSCWIKEPNRRPTFRQLKKAV
...|..|..||||||| |. |||. || ||| |      . ..|.. | .|.|. ||..        |||.. ..  .||  .|. ||||.....  
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase HMTK06.AA TK 704-969 23 2e-106 357.92 In-house 1-486 (486) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-486/486
Sequence Identity: 23% (114 aa)

LKAVKAIGAGQFG---KVYLSEYSVDGA------------------EVEGEPELRAVKMLRGQASDNDRD-------------EFLREAETMLQIGA---
.. .| .|.||||   .||. |.  ..                   . ||...  |||||.  .......             .||.||| | .  .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENLVSLCGVVLNK------------RPMLMVLEYCQYGD----LSDVLRSLRRKNIK-----------------------------------------
 |.|.|.| ||.. .            .|...|.||...||    | | ||. |.| ..                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNLGEQLHMANQLASGMQYIASK------HFVHMDLAARNCLLGPNSS-----------IRIADFG---
                               |.. ..| |. |.|.||.|..||      .|||.||||||||.| |             ..|||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LTRPHDNQKNYYKQQG-----------------------VMKLSIRWLAIDAFQ---------YKIFSEKSDVWSFAVTVWEILAYGRQPYH---
     |.| ... ..||....                        .|| |||.|  ...         |..|..||||||| |..|||. ||..||.   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------GTELKQVMKAVIAG--------------RRLSQPKECPD-------------DVWDM-LYSCWIKEPNRRPTFRQLKKAV
        | ....||. . .|               |. ||. |||             ....  . .|| ..|..||||.||... 
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase HMTK06.AA Pkinase_Tyr 704-969 38 1.6e-104 354.63 Pfam 1-270 (270) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-270/270
Sequence Identity: 38% (106 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLRGQASDND--RDEFLREAETMLQIGAHENLVSLCGVVL-NKRP--MLMVLEYCQYGDLSDV
..  | .|.|.||.||. ..     . ...    |||||. .|.. .  |..|.|||..| |.| |.|.|.| ||..  ..|  ...|.||...||| | 
ITFGKKLGEGAFGEVYKGTWKG---DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LRSLRRKNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQKNYY-KQQGVMKLSIRWLAIDAFQYKIFSEKSD
||. |  . .|.. . |.|. | |.||.| .||...| ||||||||.. |  ..|.||||.| .   . || ...|  || |.|.|  ...|..|..|||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VWSFAVTVWEILAYGRQP-YHGTELKQVMKAV-IAGRRLSQPKECPDDVWDMLYSCWIKEPNRRPTFRQLKKAV
|||| |. |||. ||.|| | |    .|....   |.|. .|. |||.. |.. .|| ..|..||||...    
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase HMTK06.AA TK-Unique 704-969 33 1.9e-86 293.47 In-house 1-294 (294) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-294/294
Sequence Identity: 33% (98 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLRGQASDNDRDEFLREAETMLQIGAHENLVSLCGVVLNKR-PMLMVLEYCQYGDLSDVLRSL
|.  . || |.|| |.  |.. .  ......   |||||.  |.| |...||.|.. | ..|.|.|.|...|.   .  |.....|||..|.| . ||. 
LEVGDVIGEGAFGQVWRGEVWGIW-KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

RRK--------NIK--------------LNLGEQLHMANQLASGMQYIAS--KHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQKNYYKQQGVMKLS
|..        |.|              ....  .| | |.|.||.|.||  |..||.||.|||.||. .  . |.|||..|  .. . | ....  ...
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

IRWLAIDAFQ--YKIF-SEKSDVWSFAVTVWEILAYGRQPYHGTELKQVMKAVIAGRRLSQPKEC-PDDVWDMLYSCWIKEPNRRPTFRQLKKAV
|||.| ....  .... ..|||||||.|. |||. .| .||.|   |..|... .| |. ||..| ....   ..||| .||  ||.|||.|.  
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase HMTK06.AA UTK 704-969 33 2.3e-86 293.2 In-house 1-296 (296) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-296/296
Sequence Identity: 33% (99 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLR-GQASDNDRD---EFLREAE---TMLQIGAHENLVSLCGVVLNKRPMLMVLEYCQYGDLS
..  . .|.|.|| |.. .. .. .| ..|  ..||| .. . ..  ...   .|..||     | |   |.|.. | ||...  |...|.||.. |||.
VQLGRQLGQGAFGEVHKARF-TQCSEHMYE-MDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLR

DVLRSLRR----KNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPN-------SSIRIADFG---LTRPHDN--------QKNYYKQQGV
..||. |.        |.| ..|.||.. |.||||..|..||| ||||||||.. .       ....|||||   ..|   .        . .||..|..
SYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQ

MKLSIRWLAIDAFQYK-IFSEKSDVWSFAVTVWEILAYGRQPYHGTELKQVMKAVIAG--RRLSQPKECPDDVWDMLYSCWIKEPNRRPTFRQLKKAV
 .. ||| |  |. .   |..||||||| |..|||...||.|| |    || ..| .|  .|. .|..||..|.... .|| ..| .||.|..| ...
DRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase HMTK06.AA Trk 704-969 36 1.1e-73 249.21 In-house 1-275 (275) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-275/275
Sequence Identity: 36% (101 aa)

LKAVKAIGAGQFGKVYLSE-YSVDGAEVEGEPELRAVKMLRGQASDNDRDEFLREAETMLQIGAHENLVSLCGVVLNKRPMLMVLEYCQYGDLSDVLRS-
.   . .| | ||||.| | |   ...   .. . ||| |.  ||.| | .| |||| .|.   |.. | . ||  . .|.||| || . |||   ||. 
IVLKWELGEGAFGKVFLAECYNLCPEQ---DKMMVAVKTLK-DASENARKDFQREAE-LLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQH

------LRRKNI-----KLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQKNYYKQQGVMKLSIRWLAIDAFQYK
      . . .       | ... |. | | |||| |.|| |||| |.|.|||| | |. ..|.|||. |      .||.  .   | |||.   . .|.
GPDAMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYR

IFSEKSDVWSFAVTVWEILAYGRQPYHGTELKQVMKAVIAGRR-LSQPKECPDDVWDMLYSCWIKEPNRRPTFRQLKKAV
 |.  |||||| |. ||.. ||.||. .   . |   . .||  | .|. || .|.|..  || .|| .| . ... ...
KFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase HMTK06.AA CTKA 704-969 34 1.8e-71 239.4 In-house 1-290 (290) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-290/290
Sequence Identity: 34% (102 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPE----------LRAVKMLRGQASDNDRDEFLREAETML--QIGAHENLVSLCGVVLNKRPMLMVLEYCQ
.     || |..| |.        |   ..|.          . |||||.  | . || .|| || .    .   | | . | ||..   |..|. |. |
HCIMFKIGEGHYGQVFR-------AWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHF-HHPNVLRLLGVCTQHKPWHMIMEHMQ

YGDLSDVLRSLRRKN------------------IKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQKNYYKQQG
||||  .||  |                     | .   ||  || | | || | |.  ||| |||.||||||    | |||||. |  .    ||  . 
YGDLHCYLRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSS

VMKLSIRWLAIDAFQYKIFSEKSDVWSFAVTVWEILAYGRQPYHGTELKQVMKAVIAG--RRLSQPKECPDDVWDMLYSCWIKEPNRRPTFRQLKKAV
   . .|| |. | .   ||  ||||.| | .|||.  |  |. .   . | .|. ..  |||  |. ||. .  .   ||  ||| |||| .|..  
QRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase HMTK06.AA Src 704-969 36 9.8e-68 229.19 In-house 1-255 (255) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-255/255
Sequence Identity: 36% (97 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLRGQASDNDRDEFLREAETMLQIGAHENLVSLCGVVLNKRPMLMVLEYCQYGDLSDVLRSLR
.| .. .|.|||| |.   .     .|       ||| |.      . . ||.||..| .   ||.||.|  |.  . | . | || . | | | |.  .
IKLCRKLGQGQFGEVWMGYWNGN-TKV-------AVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-D

RKNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQKNYYKQQGVMKLSIRWLAIDAFQYKIFSEKSDVWSFAV
..  .|.| ... || | |.||.|. |. ..| |||||| | | |.   .||||| |  .. .. |  .   |. |.| |  |..|  |. ||||||| .
GEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGI

TVWEILAYGRQPYHGTELKQVMKAVIAGRRLSQPKECPDDVWD-MLYSCWIKEPNRRPTFRQLKKAV
  .||  ||| || | . ..|...| .| |. .|..||| . .  .  || |.| .||||  | .  
LLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase HMTK06.AA Abl 704-969 36 3.1e-66 219.82 In-house 1-252 (252) Show / Hide 
Range on Protein: 704-969
Range on HMM: 1-252/252
Sequence Identity: 36% (97 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLRGQASDNDRDEFLREAETMLQIGAHENLVSLCGVVLNKRPMLMVLEYCQYGDLSDVLRSLR
.   . .| ||.| || . .   .  |       ||| |. ..   . .|||.||  | ..  |.||| | ||     |  .. |.  || | | ||.  
IMMKHKLGGGQYGEVYEGVWKRHDCTV-------AVKTLKEDTM--EVHEFLKEAAIMKEM-KHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECD

RKNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQKNYYKQQGVMKLSIRWLAIDAFQYKIFSEKSDVWSFAV
|....      |.|| |.||||.|. ..||.| ||||||||.| .  ...|||||.|    ... |  .   |  |.| | ..  |. || ||||| | |
REELPAVV--LLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMM--KDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGV

TVWEILAYGRQPYHGTELKQVMKAVIAGRRLSQPKECPDDVWDMLYSCWIKEPNRRPTFRQLKKAV
 .|||  ||  || | .|..| . .  | |. .|. ||..|....  ||  ..  ||.|... .|.
LLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase HMTK06.AA Frk 704-972 33 4e-65 222.66 In-house 1-260 (260) Show / Hide 
Range on Protein: 704-972
Range on HMM: 1-260/260
Sequence Identity: 33% (92 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLRGQASDNDRDEFLREAETMLQIGAHENLVSLCGVVLNKRPMLMVLEYCQYGDLSDVLRSLR
.. .. .|.||||.|.   . .  . |       ||| |.  .   | ..|||||  | ..  |  |..|  |   . |.... |  . | | . |... 
IQLIRRLGSGQFGEVWEGLWNNT-TPV-------AVKTLK--PGTMDPNDFLREAQIMKKL-RHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAIN

RKNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTR-PHDNQKNYYKQQGVMKLSIRWLAIDAFQYKIFSEKSDVWSFA
.|  .... ... || |.|.|| |. |. ..| |||||| |.| . ...|||||| |    .... |  .  ... |.| | .| .|. |. ||||||| 
DKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFG

VTVWEILAYGRQPYHGTELKQVMKAVIAGRRLSQPKECPDDVWDMLYSCWIKEPNRRPTFRQLK-KAVDFL
. . ||. ||| || |   ..|.. | .| |. || .||  .....  || ..|..||||  |. |  |..
ILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase HMTK06.AA DDR 704-916 36 5.1e-53 182.47 In-house 1-245 (306) Show / Hide 
Range on Protein: 704-916
Range on HMM: 1-245/306
Sequence Identity: 36% (90 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAE--------VE---GEPELRAVKMLRGQASDNDRDEFLREAETMLQIGAHENLVSLCGVVLNKRPMLMVLEYCQY
|  |..|| |||| | | |  |.| .        ..   |.| | ||||||. |....| .|..|.  |.| . | | | | || .   |..|..||  .
LIFVEKIGEGQFGEVHLCE--VEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMEN

-GDLSDVLRSLRRK-----NIK----------LNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFG--LTRPHDNQKNYYKQQG-
 |||   .           | |          .  .  .... |.|||| | .|  ||| |||.|||| |..  |.|.|||  . |    | .||. .| 
LGDLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQ-DYYRVEGF

----VMKLSIRWLAIDAFQYKIFSEKSDVWSFAVTVWEILAYGR-QPY
       . ||| |  .     |. |||||.|.||.||..   | |||
TGRQRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPY
Kinase HMTK06.AA S_TKc 704-972 21 9.7e-44 152.54 SMART 1-231 (231) Show / Hide 
Range on Protein: 704-972
Range on HMM: 1-231/231
Sequence Identity: 21% (60 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLRGQASDNDRDEFLREAETMLQIGAHENLVSLCGVVLNKRPMLMVLEYCQY--GDLSDVLRS
 . .. || | |||||.              .. |.|...        . ..|| . . .   |.|.| | .|  .   . ||.|||    ||| |....
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

LRR--KNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSIRIADFGLTRPHDNQKNYYKQQGVMKLSIRWLAIDAFQYKIFSE-KSDV
 .|  .. ...  .  ... |......|. |....| ||   | ||     | |.|||| |              .  .  ..|   .    ..  |.|.
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDW

WSFAVTVWEILAYGRQPYHGTELKQVMKAVIAGRRLSQPKECPDDVWDMLYSCWIKEPNRRPTFRQLKK------AVDFL
||. ....| |. |. |..  ......| .            .....|..  |. |.|..|||  .. .      .  ..
WSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase HMTK06.AA Pkinase 704-858 26 2.3e-20 73.12 Pfam 1-158 (293) Show / Hide 
Range on Protein: 704-858
Range on HMM: 1-158/293
Sequence Identity: 26% (45 aa)

LKAVKAIGAGQFGKVYLSEYSVDGAEVEGEPELRAVKMLRGQASDN-DRDEFLR--EAETMLQIGAHENLVSLCGVVLNKRPMLMVLEYCQYG----DLS
.. .. ||.| ||.||.     .|        . ||| .. .  .   . . .|  |.. |. .  |.| | | ... .|. . ||.|||. |    ||.
YHIGRKIGSGSFGCVYKCHHKGTGK-------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF

DVLR-SLRRKNIKLNLGEQLHMANQLASGMQYIASKHFVHMDLAARNCLLGPNSSI----RIADFGL
|... . ... . .   |  ... |...|..|. |. ..| ||   |.|.  |  |    .|.||||
DYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase HMTK06.AA DDR 934-969 27 1.2e-10 33.36 In-house 270-306 (306) Show / Hide 
Range on Protein: 934-969
Range on HMM: 270-306/306
Sequence Identity: 27% (10 aa)

LSQPKECPDDVW-DMLYSCWIKEPNRRPTFRQLKKAV
|..|  ||...  . . .||  .. .||.|... |  
LPMPPMCPYEIYNQLMCRCWRRDQSQRPSFEEIHKFL
Kinase HMTK06.AA Pkinase 893-969 20 1.9e-09 34.46 Pfam 190-293 (293) Show / Hide 
Range on Protein: 893-969
Range on HMM: 190-293/293
Sequence Identity: 20% (21 aa)

SEKSDVWSFAVTVWEILAYGRQPYHGT------ELKQVMKAVIAGRRLSQ-PKECP-------------------DDVWDMLYSCWIKEPNRRPTFRQLK
. |.|.||. ....| |  || |. |       . .|... .  ..  .. |..|.                   ..  | ...|. | |..|||..|..
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

KA--V
.   .
QHPWF