Gene HMTK05 (M.brevicollis)
HMTK05
Species: M.brevicollis
Alias: HMTK05
External Links:
Annotation:
Sequence
Protein domains of HMTK05.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PID | HMTK05.AA | PID | 1-76 | 24 | 1.2e-05 | 21.63 | Pfam | 59-143 (153) | Show / Hide |
Range on Protein: 1-76 Range on HMM: 59-143/153 Sequence Identity: 24% (21 aa) VILRITYQGLEVTDSKT---GQQLTMTPMRAFSYISILGKKQ---NFIAY-VETDRTNSIRQCHLFRSKK--TCKEVSAKVNEAF ..|.|...|....| || .. . ||| |... | .. . || . |.. ....|| |...| .... | .|| IDLHISTDGVKWIDEKTEAEQECMHDHPMRNISFCADGGDPHVDMRYFAYDICRDGPCQRFACHVFWCCKTQQAQDIAQTVGQAF |
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| PID | HMTK05.AA | PID | 263-284 | 23 | 0.001416 | 14.34 | Pfam | 1-30 (153) | Show / Hide |
Range on Protein: 263-284 Range on HMM: 1-30/153 Sequence Identity: 23% (7 aa) FEAQYLGSVPVDRN-K-------SQATCDA ||..|||.|.|.. . ....... FEVRYLGCVEVPCHMRRPDKNTRMMQCQEC |
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| PID | HMTK05.AA | PID | 295-333 | 29 | 0.002711 | 13.35 | Pfam | 113-153 (153) | Show / Hide |
Range on Protein: 295-333 Range on HMM: 113-153/153 Sequence Identity: 29% (12 aa) DERLDRLSCEIFRAGT--RAYDLCQSVNVAFQVAMEEAKQN | .. |. | .|.. |.|. |.| ||||.... .. DGPCQRFACHVFWCCKTQQAQDIAQTVGQAFQVCYQQCLRA |
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| Kinase | HMTK05.AA | HMTK | 364-629 | 55 | 1.7e-201 | 675.69 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 364-629 Range on HMM: 1-291/291 Sequence Identity: 55% (161 aa) LKPIRVLGMGQFG-----------------EVYLGLQAVKAGHGENGSNTIH-RAVKLLKDGATPADREEFLRESELMLNFNHVNLVRLVGVAVQQRPWL ||.|.|.|.|||| .|||....||.|.|...||..| ||||.|...|...||||||||.|.|....|.|||.||||..|||||| LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKDGDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQLRHPNLVQLVGVCMQQRPWL CVLEYMEYGDLRAVVKAAHEKNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSRKLPEERDVFVLTTSL-KLPIKWMA ||||||.|||||.|.|...||||.||..|||.|.||.|.||.|.|..|.|||||||||.|....|.||||||||.|.|....|...|.... |||||||| CVLEYMQYGDLRNVLKTCREKNIQLTYHEQLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKHMVKLPIKWMA IECMD--EKIFSPASDCWALGVTMWEVAAYGMVPYP--GVKNIEVQKRVREGLRLT-APEG-CDPEFFELMCSCWERQPSQRPTFDQLRKS .|.|| .||||..||.|| ||||||...||..||. ..||.|||..||||.||| .|.. |...|..|||.||...|.|||||.||.|. PEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM |
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| Kinase | HMTK05.AA | Pkinase_Tyr | 364-630 | 39 | 4.7e-111 | 376.74 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 364-630 Range on HMM: 1-270/270 Sequence Identity: 39% (109 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLKDGATPAD--REEFLRESELMLNF-NHVNLVRLVGVAV-QQRP--WLCVLEYMEYGDLR .. ...|| |.|||||.| . ....|. ||| ||.||.. . ||.|.|| ..| .. .| |.|||.|| . |..| .. |.|||..|||. ITFGKKLGEGAFGEVYKGTWKG-----DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL AVVKAAHEKNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSRKL-PEERDVFVLTTSLKLPIKWMAIECMDEKIFSPA .. | . ||. . |....||| ||.| . ....| ||||||.|....| |||.||||.| . ... .. ... |||||||| ||. ...|. . DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTK SDCWALGVTMWEVAAYGMVP-YPGVKNIEVQKRV-REGLRLTAPEGCDPEFFELMCSCWERQPSQRPTFDQLRKSI || |. ||.|||. ||. | |||..| || ... ..| |. .||.| .| .||..||. .|..|||| ... . SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | HMTK05.AA | TK | 364-630 | 23 | 2e-107 | 361.28 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 364-630
Range on HMM: 1-486/486
Sequence Identity: 23% (113 aa)
LKPIRVLGMGQFG---EVYLG-LQAVKAGHGENG---------------SNTIHRAVKLLKDGATPADRE-------------EFLRESELMLNFN----
.. ...|| |||| |||.| .. . ..|... ... ||| ||.|.. ...| .||.| | | ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
-HVNLVRLVGVAVQQ------------RPWLCVLEYMEYGD----LRAVVKAAHEKNIT-----------------------------------------
| |.|||.|| .|. .||..|.|||..|| || .. ..| ..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------LTLLEQLKFAVQIATGMDYMAKH------RFVHMDLAARNVLLSSKNL-----------VKIADFG---
||. ..| ...||| || |.... .|||.||||||.|....| .||||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-----LSRKLPEERDVFVLT-----------------------TSLKLPIKWMAIECMDEKI---------FSPASDCWALGVTMWEVAAYG-MVPYPGV
|.|..... | . . .. ||||.||| ||..... |...|| |..||.|||. || . .|.|.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
KN---------IEVQKRVREG--------------LRLTAPEGCD--------------PEFFELMCSCWERQPSQRPTFDQLRKSI
| || ...|.| .|. .|..| .|...||..||...|..||||.||.. .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | HMTK05.AA | TyrKc | 364-630 | 36 | 2.9e-107 | 363.56 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 364-630 Range on HMM: 1-280/280 Sequence Identity: 36% (108 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLKDGATPADREEFLRESELMLNF--NHVNLVRLVGVAVQQ-------RPWLCVLEYMEYG .. ...|| |.|||||.| | ||| ||..| ||.|.|| ..| .. .| |.|||.||..|| | . |.|||..| ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG DLRAVVKAAHEKNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSRKLPEE------RDVFVLTT--SLK--LPIKWMA ||. .. ..| |.. . |.|..||| ||.| ......| ||||||.|..... |||.||||||.. .. |. . .. . | |||.||| DLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA IECMDEKIFSPASDCWALGVTMWEVAAYGMVPYPG-----VKNIEVQKRVREGLRLTAPEG--------CDPEFFELMCSCWERQPSQRPTFDQLRKSI .||.....|...|| |. ||.|||. ||. |||| ..|.|| ..|..| |. |. | .| ...| .||...|..|||| .... . PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | HMTK05.AA | UTK | 364-630 | 33 | 9.7e-87 | 294.47 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 364-630 Range on HMM: 1-296/296 Sequence Identity: 33% (99 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLK-DGATPADRE---EFLRESE---LMLNFN-HVNLVRLVGVAVQQRPWLCVLEYMEYGD ... | || |.||||... .. . . . . ..||| .. ..... ..| .|..|. .| .|. |.|..||||| .|. ||. |.|||| || VQLGRQLGQGAFGEVHKA----RFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGD LRAVVKAAHE----KNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSK-------NLVKIADFG---LSRKLPE--------ERDVFVLT ||... ... ||| ..|..|..|| || |.. ..||| ||||||.|. . ...|||||| .|| .. | . . . LRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQ TSLKLPIKWMAIECMDEK-IFSPASDCWALGVTMWEVAAYGMVPYPGVKNIEVQKRVREG--LRLTAPEGCDPEFFELMCSCWERQPSQRPTFDQLRKSI ..||.||| |.... |. .|| |..||..||. ..| .|||| | .| ..|..| .|. .|..| . ..|| .||. |. ||.|..|.. . HQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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| Kinase | HMTK05.AA | Src | 364-630 | 38 | 1.8e-82 | 280.03 | In-house | 1-255 (255) | Show / Hide |
Range on Protein: 364-630 Range on HMM: 1-255/255 Sequence Identity: 38% (103 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLKDGATPADREEFLRESELMLNFNHVNLVRLVGVAVQQRPWLCVLEYMEYGDLRAVVKAA .| .| || ||||||. |. .... ||| || | . | ||.| ..| .. | .||.| | | | . | |||. | | . |. IKLCRKLGQGQFGEVWMGYWN----------GNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK- HEKNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSRKLPEERDVFVLTTSLKLPIKWMAIECMDEKIFSPASDCWALG .. .| | ... .| |.| ||.|. . ...| |||||||| . .|..|.||||| | . |. |. . . |.||||.| |. .. |. || | | DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFG VTMWEVAAYGMVPYPGVKNIEVQKRVREGLRLTAPEGCDPEFFE-LMCSCWERQPSQRPTFDQLRKSI . ..|. || ||||| .| || ..| | |. |..| .|..| .|. ||...| |||||. |.. ILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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| Kinase | HMTK05.AA | TK-Unique | 364-630 | 31 | 7.9e-82 | 278.17 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 364-630
Range on HMM: 1-294/294
Sequence Identity: 31% (93 aa)
LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLKDGATPADREEFLRESELMLNFN-HVNLVRLVGVAVQQR-PWLCVLEYMEYGDLRAVVK
|. .|.|.|.||.|. | .... .. . ... |||.|||.||. |. .||.| ..| . | |.|...|. . ||. ..||...|.|. .
LEVGDVIGEGAFGQVWRG-EVWGIW--KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLR
AAHEK--------NIT--------------LTLLEQLKFAVQIATGMDYMAK--HRFVHMDLAARNVLLSSKNLVKIADFGLSRKLPEERDVFVLTTSLK
. |. ... . ||.||| || |.|. ...||.||.||||||.... .||.|||..|.. .... ... .
TCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR
LPIKWMAIECMD--EKIF-SPASDCWALGVTMWEVAAYGMVPYPGVKNIEVQKRVREGLRLTAPEGC-DPEFFELMCSCWERQPSQRPTFDQLRKSI
.||.||| | . .... .. || |..||.|||.. .| ||||... ......|.| |. ||.| .|...|| ||| . |..||.|.|... .
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
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| Kinase | HMTK05.AA | Fer | 364-631 | 29 | 3.8e-78 | 265.7 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 364-631 Range on HMM: 1-283/283 Sequence Identity: 29% (88 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHR-----------AVKLLKD-GA-TPAD-REEFLRESELMLN-FNHVNLVRLVGVAVQQRPWLCVL . . .|| | |||||.| . |... ||| | .. . .. ..||..| .|.| ..| | |.. ||.|.. | . |. VTLGKKLGEGAFGEVYKGR-----------R-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVM EYMEYGDLRAVVKAAHEKNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSS-KNLVK--IADFGLSRKLPEERDVFVLT-TSLKLPIKWMA |.. |.|. | ..| |... | .... |.| ||.|. .. .| |.||||.|.. |. .| |.|||.||.. .. . .. |.||.|.| EFCNGGSLDSYLKKNKNK--TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLA IECMDEKIFSPASDCWALGVTMWEVAAYGMVPYPG----VKNIEV----QKR-VREGLRLTAPEGCDPEFFELMC-SCWERQPSQRPTFDQLRKSIL |... .|.||..| |. ||..||. . | |||| .|. .| .|. ...| ... |... ||. ..|. .||.. |..|||...... . PETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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| Kinase | HMTK05.AA | Abl | 364-630 | 38 | 5.5e-74 | 246.09 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 364-630 Range on HMM: 1-252/252 Sequence Identity: 38% (103 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLKDGATPADREEFLRESELMLNFNHVNLVRLVGVAVQQRPWLCVLEYMEYGDLRAVVKAA . || ||.|||| ..| | ..|. ||| ||. . . .|||.| .| . | |||.|.|| . |. . |.| || | .. . IMMKHKLGGGQYGEVY---EGVWKRH----DCTV--AVKTLKEDTMEV--HEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLREC HEKNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSRKLPEERDVFVLTTSLKLPIKWMAIECMDEKIFSPASDCWALG ..... | | | ||| ||.|. |. |.| |||||| |.. ...||.|||||.| . . |.. | |||| | | . . || || || | DREELPAVVL--LYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKD--DTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFG VTMWEVAAYGMVPYPGVKNIEVQKRVREGLRLTAPEGCDPEFFELMCSCWERQPSQRPTFDQLRKSI | .||.| ||| ||||. .| ... .| |. |||| |. .||| ||. ... ||.| .. . . VLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM |
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| Kinase | HMTK05.AA | CTKA | 400-630 | 37 | 5.9e-72 | 241.03 | In-house | 38-290 (290) | Show / Hide |
Range on Protein: 400-630
Range on HMM: 38-290/290
Sequence Identity: 37% (94 aa)
AVKLLKDGATPADREEFLRESELML--NFNHVNLVRLVGVAVQQRPWLCVLEYMEYGDLRAVVKAAHEKN------------------ITLTLLEQLKFA
||| ||| || .||..|| | . | | | .||.|| | ||. . |.| ||||. ...| | . || |
AVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYLRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMA
VQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSRKLPEERDVFVLTTSLKLPIKWMAIECMDEKIFSPASDCWALGVTMWEVAAYGMVPYPG
||| ||.| | ||| |||.||.|| . . .||||||..| | | ... . .|. |||.| . . || ||| || || .||.. | |. .
MQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRH
VKNIEVQKRVREG--LRLTAPEGCDPEFFELMCSCWERQPSQRPTFDQLRKSI
|| . . . || | | .| || | ||||| .|...
MSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
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| Kinase | HMTK05.AA | Frk | 364-634 | 36 | 2.7e-70 | 239.84 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 364-634 Range on HMM: 1-260/260 Sequence Identity: 36% (98 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLKDGATPADREEFLRESELMLNFNHVNLVRLVGVAVQQRPWLCVLEYMEYGDLRAVVKAA .. || || ||||||. || ||. ||| || |. .| ..|||| .| . | |..| | . | . . | |. | | ..| IQLIRRLGSGQFGEVWEGLWN----------NTTPVAVKTLKPGT--MDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAI HEKNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSR-KLPEERDVFVLTTSLKLPIKWMAIECMDEKIFSPASDCWAL .| . . ... | |.|.|| |. .. ..| ||||||||. .| .||||||| | . .. |.. . ..|||| | | . . |. || |. NDKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSF GVTMWEVAAYGMVPYPGVKNIEVQKRVREGLRLTAPEGCDPEFFELMCSCWERQPSQRPTFDQLRKSILGLA |. . |. || .||||. | || . | .| |. | .|.....|.| ||. .| .||||. |. . GILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF |
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| Kinase | HMTK05.AA | Axl | 364-628 | 37 | 6.8e-70 | 238.52 | In-house | 1-267 (267) | Show / Hide |
Range on Protein: 364-628 Range on HMM: 1-267/267 Sequence Identity: 37% (104 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLK-DGATPADREEFLRESELMLNFNHVNLVRLVGVAVQQRP------WLCVLEYMEYGDL . ..|| | || | | | . ||| .| | | . ||||.| | .|.| | .||.||..|.. . .| .| .||| FVLGKMLGEGEFGSVMEGQLKQEDG------SFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDL RAVVKAA--HEKNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSRKLPEERDVFVLTTSLKLPIKWMAIECMDEKIFS . . .. .. . | | .|| | ||.||.|.....|.| |||||| .| | .||||||.|. . | . |.|.||.||| . .... HTFLLYSRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKI-YSGDYYRQGCIAKMPVKWIAIESLADRVYT PASDCWALGVTMWEVAAYGMVPYPGVKNIEVQKRVREGLRLTAPEGCDPEFFELMCSCWERQPSQRPTFDQLRK || || ||||||.. |. |||||.| |. ...| || || | | ..|| .||| .| .||.| .||. SKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCMDELYDLMYQCWEADPKDRPSFSVLRE |
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| Kinase | HMTK05.AA | S_TKc | 364-631 | 22 | 7.7e-45 | 156.21 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 364-631
Range on HMM: 1-231/231
Sequence Identity: 22% (62 aa)
LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVKLLKDGATPADREEFLRESELMLNFNHVNLVRLVGVAVQQRPWLCVLEYMEY--GDLRAVVK
. .|..| | ||.||.. . |.| .| | ..|| ... . .| |.|.| .| . |.||.. |||. . |
YEILRKIGKGAFGKVYKCRHKK---------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK
AAHE--KNITLTLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLVKIADFGLSRKLPEERDVFVLTTSLKLPIKWMAIECMDEKIFSP-ASD
.. .. . ... ||. ...|. .|...| || |.||.. .||.||||.|.| |.. .|| | . ... ..|
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCD
CWALGVTMWEVAAYGMVPYPGVKNIEVQKRVREGLRLTAPEGCDPEFFELMCSCWERQPSQRPTFDQLRK--------SIL
|..|....| .. | |.| .. |... .||. .... |... |..||| .. . .
WWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | HMTK05.AA | Pkinase | 364-523 | 24 | 5.1e-22 | 78.94 | Pfam | 1-162 (293) | Show / Hide |
Range on Protein: 364-523 Range on HMM: 1-162/293 Sequence Identity: 24% (43 aa) LKPIRVLGMGQFGEVYLGLQAVKAGHGENGSNTIHRAVK-LLKDGATPADREEFLR--ESELMLNFNHVNLVRLVGVAVQQRPWLC-VLEYMEYG----D .. .|..| | ||.||.. ||| . |... . ... .| | ..|...|| | ||| .. ..... |.||.| | | YHIGRKIGSGSFGCVYKCHHKGTGK---------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMD LRAVVKAAHEKNITL--TLLEQLKFAVQIATGMDYMAKHRFVHMDLAARNVLLSSKNLV----KIADFGLSRKL | ..... ... .. . | ... ||. |..|. .....| || |.|..... . ||.||||.... LFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQF |
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| Kinase | HMTK05.AA | Pkinase | 554-630 | 15 | 7.6e-12 | 42.96 | Pfam | 190-293 (293) | Show / Hide |
Range on Protein: 554-630 Range on HMM: 190-293/293 Sequence Identity: 15% (16 aa) SPASDCWALGVTMWEVAAYGMVPYPGV----KNIEVQKRVREGLRLTAPEGCD-----------------------PEFFELMCSCWERQPSQRPTFDQL .|..| |..|....|.. | |.|| . .. ...... .. .. .. .|. .....|... |..|||..|. GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI RKS--I .. . LQHPWF |
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