Gene HMTK03 (M.brevicollis)

HMTK03

Species: M.brevicollis
Alias: HMTK03
External Links:
Annotation:

Classification

Group: TK
Family: HMTK

Sequence

Name Sequence Type Origin Length Description Download
HMTK03.AA Protein None 1325 None Fasta, JSON
HMTK03.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of HMTK03.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PTB HMTK03.AA PTB 351-493 18 2.7e-05 23.61 SMART 1-156 (156) Show / Hide 
Range on Protein: 351-493
Range on HMM: 1-156/156
Sequence Identity: 18% (31 aa)

RHGYKVQGYYLGHELVNALR-------GKHVCQDAMMRNSTRWRELQRRRPNEKPRGIVLTITESLVHAEDMQAGTPLFSHFLKTVSFTCVALQ------
 .| .    |||   | . |       |  |||..| . .           ........| |. . |.  | | .. . .| ....|| |.. .      
PWGCCFNVWYLGCVEVPHHRNSMAPGKGMQVCQECMRKIR---------QHWKHWQKMHLHISVDGVKLIDPQTKQVIHHHPIHRISF-CAHDPYRWNTG

---SPDRGDVFAYIRNDDKIG-------HVQCHLFQLRFGDGDKLTAAVSEAFQILSEQSKALGDD
   ..|  ..|.||  ..          . .||.|.      . . ... .|||   .|...   .
GHHCCDDDRCFGYICRHPNDRGSHRMTYWFRCHVFWCEDPHAEDIAQTIGQAFQVCYQQCQKQRCQ
Kinase HMTK03.AA HMTK 519-784 56 7.2e-201 673.6 In-house 1-291 (291) Show / Hide 
Range on Protein: 519-784
Range on HMM: 1-291/291
Sequence Identity: 56% (163 aa)

LKAIKQIGAGQFG-----------------DVWLAKQKVAPGQGEGGSDSIT-RAVKLLRGAASAADKEEFLHEAEVMLELRHDHLIRIIGVALQQKPWL
|||||.|||||||                 .|.||...|..|.|. .|.... ||||.|||.||..|.||||.|||||..|||..|....||..||.|||
LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKDGDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQLRHPNLVQLVGVCMQQRPWL

CVLEYMQYGDLRSVLMACKEKGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYFLLRTRL-KLALKWCS
||||||||||||.||..|.||..||..||.. .|.|.|.|||..|..||||||||||||....||.||..|||||.|||.|.||..||... ||..||..
CVLEYMQYGDLRNVLKTCREKNIQLTYHEQLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKHMVKLPIKWMA

PEGLD--EKIFSEASDVWSFGVLMWEIMMYGEAPYE--EIELRDVQRYVREGGRLTQPPD--CPDKTFAVMKKCWNSDRRTRWTFSALQRM
||..|  .|||||.||||.|||.||||.||||.|||  .|....|||.||||.||||||.  |||.....|..||..|...|.||..||.|
PEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM
Kinase HMTK03.AA TK 519-785 22 3.3e-104 350.33 In-house 1-486 (486) Show / Hide 
Range on Protein: 519-785
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

LKAIKQIGAGQFG---DVWLAKQKVA-PGQGEGGSDS---------------ITRAVKLLRGAASAADKE-------------EFLHEAEVMLELR----
.. .|..|.||||   .|.... .   |..|......               .. ||| |.  ......|             .|| |||.|  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HDHLIRIIGVALQQ------------KPWLCVLEYMQYGD----LRSVLMACKEKGLQ-----------------------------------------
 |....|..|| .|.            .||..|.|||..||    ||. | .|..|. .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LHLHEMIVWCTQLAKGMAFMAES------RMVHMDLAARNCMLASNNV-----------VKVGDFG---
                               |..|... .| |.|.||.....       ..||.|||||||....|||           .|..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LTQRLDEGHDYFLLR-----------------------TRLKLALKWCSPEGLDEKI---------FSEASDVWSFGVLMWEIMMYGEAPYE---
     |. ......||   .                       .. || ..|..|| |....         |...|||||||||||||..||..||    
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------EIELRDVQRYVREGGRL--------------TQPPDCP--------------DKTFAVMKKCWNSDRRTRWTFSALQRML
        . ....| .|.|.||||               |||.||              .  . .|..||. | . | |||.|...|
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase HMTK03.AA TyrKc 519-785 33 3.5e-103 350.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 519-785
Range on HMM: 1-280/280
Sequence Identity: 33% (100 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAADKEEFLHEAEVMLEL--RHDHLIRIIGVALQQ-------KPWLCVLEYMQYG
.. .|..| |.|| |.... |            |. ||| |.  |    .|.|..||..| .|  .|....|..||..||       .| . |.||| .|
ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

DLRSVLMACKEKGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEG------HDYFLLRT--RLK--LALKWCS
||.. | ....|   | . ... .|.| |.||.. .. . .| |||||||....|..||..||||.  ....      .||   ..    |  | ..|..
DLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEGLDEKIFSEASDVWSFGVLMWEIMMYGEAPYEE-----IELRDVQRYVREGGRLTQPPD--------CPDKTFAVMKKCWNSDRRTRWTFSALQRML
|| .....|...||||||||.||||. ||. ||..     .. ..| .||..|.|. |||.        |||. . .||.||. |   | |||.. . .
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase HMTK03.AA Pkinase_Tyr 519-785 37 1.1e-102 348.46 Pfam 1-270 (270) Show / Hide 
Range on Protein: 519-785
Range on HMM: 1-270/270
Sequence Identity: 37% (104 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAAD--KEEFLHEAEVMLEL-RHDHLIRIIGVAL-QQKP--WLCVLEYMQYGDLR
.. .|..|.|.||.|.... |      ..... |. ||| |.  |.  .  .|.|..||..| .| .|....| .|| . |..|  .. |.|||..|||.
ITFGKKLGEGAFGEVYKGTWKG-----DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

SVLMACKEKGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYF-LLRTRLKLALKWCSPEGLDEKIFSEA
. | . .| . .| ..... .|.| ||||.. .. ...| |||||||....|||||..||||.  . .  ||    |.  ||  ||..|| . ...|...
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTK

SDVWSFGVLMWEIMMYGEAP-YEEIELRDVQRYV-REGGRLTQPPDCPDKTFAVMKKCWNSDRRTRWTFSALQRML
|||||||||||||. ||| | |...   .| .|. ..|.|. .|..|||.   .||.||. |   | |||.....|
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase HMTK03.AA UTK 519-785 30 1e-83 284.43 In-house 1-296 (296) Show / Hide 
Range on Protein: 519-785
Range on HMM: 1-296/296
Sequence Identity: 30% (90 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLR-GAASAADKE---EFLHEAE---VMLELR-HDHLIRIIGVALQQKPWLCVLEYMQYGD
..  .|.|.|.||.| .|. . ......       .||| .. .|..  ..|   .|. ||    .|  .. | ...| .|| .|..||. |.|||. ||
VQLGRQLGQGAFGEVHKARFTQCSEHMY----EMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGD

LRSVLMACKE----KGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASN-------NVVKVGDFG---LTQRLDE--------GHDYFLLR
|||.|. ...     ...| ||... .. . | ||..... . || ||||||| ....       .|.|..|||   .. |.          . .|.  .
LRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQ

TRLKLALKWCSPEGLDEK-IFSEASDVWSFGVLMWEIMMYGEAPYEEIELRDVQRYVREGG--RLTQPPDCPDKTFAVMKKCWNSDRRTRWTFSALQRML
 . .....|..|| |..   |...||||||||..|||...| .||...  ..|   |..||  |. .|.|||.  . .|..||..| . | .|  |   .
HQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase HMTK03.AA CTKA 519-785 35 7.3e-75 250.95 In-house 1-290 (290) Show / Hide 
Range on Protein: 519-785
Range on HMM: 1-290/290
Sequence Identity: 35% (103 aa)

LKAIKQIGAGQFGDVWLAKQKVAPG----QGEGGSDSITRAVKLLRGAASAADKEEFLHEAEVML--ELRHDHLIRIIGVALQQKPWLCVLEYMQYGDLR
.    .|| |..|.|  |  .  |     |   | |    ||| |.  |  .| ..||||| |     . |   .| .|| .| |||. . |.||||||.
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDV---AVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLH

SVLMACKEKG------------------LQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYFLLRTRLKLA
..| ||                      . .| || . .  | | || . ||  .|| |||.|||.| . ...|. |||.   |. .  |. .  .  . 
CYLRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMP

LKWCSPEGLDEKIFSEASDVWSFGVLMWEIMMYGEAPYEEIELRDVQRYVREG--GRLTQPPDCPDKTFAVMKKCWNSDRRTRWTFSALQRML
  | .|| | .  || |||||.||||.||||  || |.     . |   .  .   ||  |. ||.     |. ||      | ||  |||||
VRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase HMTK03.AA TK-Unique 519-785 28 4.4e-73 249.12 In-house 1-294 (294) Show / Hide 
Range on Protein: 519-785
Range on HMM: 1-294/294
Sequence Identity: 28% (85 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAADKEEFLHEAEVMLELR-HDHLIRIIGVALQQK-PWLCVLEYMQYGDLRSVLM
|.  ..|| |.|| || .. .  .   .. .. .  |||.|.  |.  || .|| |...| ||  | ......|.      ||. ..||...|.|.. | 
LEVGDVIGEGAFGQVWRGEVWGIW---KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLR

ACKEK--GLQ--------------------LHLHEMIVWCTQLAKGMAFMAE--SRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYFLLRTRLK
 |. .  . |                    . .. .. .. |.|.||...|.   . ||.||.|||..|....|.|..|||.. ... ...|   ... .
TCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR

LALKWCSPEGLD--EKIF-SEASDVWSFGVLMWEIMMYGEAPYEEIELRDVQRYVREGGRLTQPPDC-PDKTFAVMKKCWNSDRRTRWTFSALQRML
. ..|..|| |   .... .. |||||||||||||. .|. || ..  .|... .|.| |. ||. | .. .. .|| ||....  | .|...  .|
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase HMTK03.AA Src 519-785 36 8.5e-73 246.65 In-house 1-255 (255) Show / Hide 
Range on Protein: 519-785
Range on HMM: 1-255/255
Sequence Identity: 36% (99 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAADKEEFLHEAEVMLELRHDHLIRIIGVALQQKPWLCVLEYMQYGDLRSVLMAC
.| ....|.||||.|| .. .          ...  ||| |. .    . | || ||..| .|||..|...  |  | .| . | |||. | |   | . 
IKLCRKLGQGQFGEVWMGYWN----------GNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-

KEKGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYFLLRTRLKLALKWCSPEGLDEKIFSEASDVWSFG
...| .||| . |   .| |.|||.. . ...| ||||||     |||.||.|||| . ..|. |    |.  |.  ||  || ...  |.  |||||||
DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFG

VLMWEIMMYGEAPYEEIELRDVQRYVREGGRLTQPPDCPDKTFA-VMKKCWNSDRRTRWTFSALQRML
.|..||. ||  ||.  . ..| . |  | |. .|. |||. .  .|..||..| . | ||  ||  |
ILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase HMTK03.AA Frk 519-789 34 1.5e-68 234.05 In-house 1-260 (260) Show / Hide 
Range on Protein: 519-789
Range on HMM: 1-260/260
Sequence Identity: 34% (93 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAADKEEFLHEAEVMLELRHDHLIRIIGVALQQKPWLCVLEYMQYGDLRSVLMAC
.. |...|.||||.||  .  ..          .  ||| |.  . ..| ..|| || .| .|||  ||..  |   ..| . . | |. | |   | | 
IQLIRRLGSGQFGEVWEGLWNNT----------TPVAVKTLK--PGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAI

KEKGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQ-RLDEGHDYFLLRTRLKLALKWCSPEGLDEKIFSEASDVWSF
..|| |.......    |.| |||.. .   .| |||||| ..  .|..|. ||||    . .  | .  |.  .. .||  ||    . |.  ||||||
NDKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSF

GVLMWEIMMYGEAPYEEIELRDVQRYVREGGRLTQPPDCPDKTFAVMKKCWNSDRRTRWTFSALQRMLDGEL
|.|. ||. ||  ||  .  ..|   | .| |. |||.|| . . .| .||.|| . | ||  ||  |.  .
GILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase HMTK03.AA EGFR 519-786 37 1.3e-65 216.77 In-house 1-258 (258) Show / Hide 
Range on Protein: 519-786
Range on HMM: 1-258/258
Sequence Identity: 37% (100 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAADKEEFLHEAEVMLELRHDHLIRIIGVALQQKPWLCVLEYMQYGDLRSVLMAC
|| .|  |.| || |.  |    |   || .  |  |.| || . ..  .||.| || ||  ..|.||.|..|| ....    |  || || |   .   
LKKVKVLGSGAFGTVY--KGIWIP---EGENVKIPVAIKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLGVCMHSQ-MQLVTQYMPYGCLLDYVRQH

KEKGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYFLLRTRLKLALKWCSPEGLDEKIFSEASDVWSFG
|.   ..  .... ||.| |||| .. | |||| |||||| .. | | ||. |||| . |.   . .      |.. ||   | . ....  .|||||.|
KD---NIGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGG-KMPIKWMALECIHHRCYTHQSDVWSYG

VLMWEIMMYGEAPYEEIELRDVQRYVREGGRLTQPPDCPDKTFAVMKKCWNSDRRTRWTFSALQRMLD
| .||.| .|. ||. |..|..   . .| || ||| |    . || |||  |   | ||  |.  ..
VTCWELMTFGQKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase HMTK03.AA Abl 519-785 33 1.1e-63 211.17 In-house 1-252 (252) Show / Hide 
Range on Protein: 519-785
Range on HMM: 1-252/252
Sequence Identity: 33% (89 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAADKEEFLHEAEVMLELRHDHLIRIIGVALQQKPWLCVLEYMQYGDLRSVLMAC
.   ...| ||.|.|. .  |           . | ||| |.  . .   .|||.|| .| |..|  |....||  .  |.  . |.| || |   |  |
IMMKHKLGGGQYGEVYEGVWKRH---------DCTVAVKTLKEDTMEV--HEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLREC

KEKGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYFLLRTRLKLALKWCSPEGLDEKIFSEASDVWSFG
... |.     ..   ||.| || .. .   .| |||||||... ...||| ||||.  . .  | .  .   |  .||  ||.|  . ||  |||| ||
DREELPAVV--LLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKD--DTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFG

VLMWEIMMYGEAPYEEIELRDVQRYVREGGRLTQPPDCPDKTFAVMKKCWNSDRRTRWTFSALQRML
||.|||  || .||  |.| .|   . .| |. .|. ||.| . .|..||. .   | .|  . ...
VLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase HMTK03.AA Axl 519-783 34 7.4e-62 211.81 In-house 1-267 (267) Show / Hide 
Range on Protein: 519-783
Range on HMM: 1-267/267
Sequence Identity: 34% (94 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASA-ADKEEFLHEAEVMLELRHDHLIRIIGVALQQKP------WLCVLEYMQYGDL
.   | .| | || |  .. |    | .| .  .  ||| .. . ..  . |||| ||  | |  | . .|.|||..|..        . .| .|..|||
FVLGKMLGEGEFGSVMEGQLK----QEDGSFVKV--AVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDL

RSVLMACK--EKGLQLHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYFLLRTRLKLALKWCSPEGLDEKIFS
 . |.. .  ..   |.|  .. .   .| || .... . .| |||||||||. .  | | |||| ... .| ||.      |.  ||   | | .... 
HTFLLYSRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSG-DYYRQGCIAKMPVKWIAIESLADRVYT

EASDVWSFGVLMWEIMMYGEAPYEEIELRDVQRYVREGGRLTQPPDCPDKTFAVMKKCWNSDRRTRWTFSALQR
  ||||.||| |||||  |  ||  .|  ..  |...| || ||.|| |. ...| .||. | . | .|| |. 
SKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase HMTK03.AA S_TKc 519-792 17 7.4e-36 126.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 519-792
Range on HMM: 1-231/231
Sequence Identity: 17% (49 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAADKEEFLHEAEVMLELRHDHLIRIIGVALQQKPWLCVLEYMQY--GDLRSVLM
 . ...|| | || |.... |          .    |.| ..        | .. | ... . .|........|    .    |.||.    |||.... 
YEILRKIGKGAFGKVYKCRHKK---------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK

ACKEKGLQ--LHLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVVKVGDFGLTQRLDEGHDYFLLRTRLKLALKWCSPEGLDEKIFSE-ASD
 .. .||.  ..  .   .. |........ . . .| ||   | .| .  ..|..||||  .|          | .   . ...|| |    ..  ..|
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCD

VWSFGVLMWEIMMYGEAPYEEIELRDVQRYVREGGRLTQPPDCPDKTFAVMKKCWNSDRRTRWTFSALQR--MLDGELRFL
.||.|....| .  |. |..  ..  . . ..           ..     ..||.. | . |.|   . .  ..     ..
WWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase HMTK03.AA Pkinase 519-674 20 5.4e-18 64.7 Pfam 1-158 (293) Show / Hide 
Range on Protein: 519-674
Range on HMM: 1-158/293
Sequence Identity: 20% (35 aa)

LKAIKQIGAGQFGDVWLAKQKVAPGQGEGGSDSITRAVKLLRGAASAADKEE--FLH--EAEVMLELRHDHLIRIIGVALQQKPWLC-VLEYMQYG----
.. ...||.| || |.... |  .          . ||| ..   .. ....   ..  |...|..|.|.. .|....    |.... |.||.. |    
YHIGRKIGSGSFGCVYKCHHKGTGK---------IVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVM

DLRSVLMACKEKGLQL--HLHEMIVWCTQLAKGMAFMAESRMVHMDLAARNCMLASNNVV----KVGDFGL
|| .....  ...  .    .| . ...|...|.... . . .| ||   |... .|...    |..||||
DLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase HMTK03.AA Pkinase 697-785 15 3.2e-07 26.61 Pfam 177-293 (293) Show / Hide 
Range on Protein: 697-785
Range on HMM: 177-293/293
Sequence Identity: 15% (18 aa)

WCSPEGLD-EKIFSEASDVWSFGVLMWEIMMYGEAPYEEI----ELRDVQRYVREGGRLTQPPDCP-----------------------DKTFAVMKKCW
...|| .   .  . ..|.||.|....| |. |. |. .     . .| .  ... ..   . |.|                       .    ..|.|.
YMAPEVIRGGQYYGPKVDMWSCGCILYE-MLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

NSDRRTRWTFSALQRM--L
. |   |.|.  .     .
CKDPKKRPTAEQILQHPWF