Gene Csk (M.brevicollis)

Csk

Species: M.brevicollis
Alias: Csk
External Links:
Annotation:

Classification

Group: TK
Family: SFK-Csk

Sequence

Name Sequence Type Origin Length Description Download
Csk.AA Protein None 448 None Fasta, JSON
Csk.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of Csk.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 Csk.AA SH3 7-64 30 3.9e-20 74.15 SMART 1-58 (58) Show / Hide 
Range on Protein: 7-64
Range on HMM: 1-58/58
Sequence Identity: 30% (18 aa)

TNVVALFDFAGESSEDLPFKRNEPLTIVKVASDSNWWLARNS-KGKTGMIPANYVRPVG
  |.||.|. ......|.||... .|...   |..|| .|.  .|..|..|.|||... 
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 Csk.AA SH3_1 10-57 28 2.1e-17 61.65 Pfam 1-49 (49) Show / Hide 
Range on Protein: 10-57
Range on HMM: 1-49/49
Sequence Identity: 28% (14 aa)

VALFDFAGESSEDLPFKRNEPLTIVKVASDSNWWLARNSK-GKTGMIPA
|||.|........|.||... .....   |..|| .|.   |..|..|.
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 Csk.AA SH3_2 8-63 18 2.5e-10 39.06 Pfam 1-68 (68) Show / Hide 
Range on Protein: 8-63
Range on HMM: 1-68/68
Sequence Identity: 18% (13 aa)

NVVALFDFAG-ESSED-----LPFKRNEPLTIVKVA-----SDSNWWLA-RN-SKGKT--GMIPANYVRPV
 .....|. . .. ..     | ||...   ..||      .. |||.. .. ..|..  | .| ..|...
YYRVHCDYVPATYCNENHEPQLHFKKGD---VIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 Csk.AA SH2 81-155 46 2e-34 102.88 Pfam 1-81 (81) Show / Hide 
Range on Protein: 81-155
Range on HMM: 1-81/81
Sequence Identity: 46% (38 aa)

WFHGKINRTVAEELIAG--KPVGTFLVRESTNFPGDYTLTVVGTE---AVDHYHIQSKGGK-ITIDDEVSFGSLDELISHY
|.||||.|  ||.|     .| |||||||| . ||||||.|.       | ||.||. ...   | ... |.|| ||..||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 Csk.AA SH2 79-161 43 9.7e-33 116.0 SMART 1-87 (87) Show / Hide 
Range on Protein: 79-161
Range on HMM: 1-87/87
Sequence Identity: 43% (38 aa)

MPWFHGKINRTVAEELIAG--KPVGTFLVRESTNFPGDYTLTVVGTEAVDHYHIQSKG-GKITIDD--EVSFGSLDELISHYTQDADG
.||.||.|.|  ||.|  .  .| |.||||.| ..||||.|.|   . | ||.|.... ||  ||.  ...| || ||. ||.. ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase Csk.AA Csk 194-442 55 1.3e-140 473.43 In-house 1-251 (251) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-251/251
Sequence Identity: 55% (141 aa)

LIKGAKLGSGQFGDVFEGTYCGQRVAIKTLKNYEQSLRDEFLAEASVMTKLKHPNLVKLEGVVTEGK-EIMLVTEYMAKGNLLDFLRSRGRSVVKKDLLF
|  |.. | | ||||  |.| .. ||.| .|.      . |||||||||.|.|||||.| ||. . | .. .|.|||.||||.|.||||||.|.... | 
LHLGECIGHGEFGDVMQGEYQNRKVAVKCIKCDGNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLRSRGRHVITRRQLL

KFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAK--RSDWGDIDSGKLPIKWTAPEVLKHKVSTSKSDVWSFGITMWEIYSYGRSPYPR
||  |.||||..||. ..|||||||||.|.||..|||| ||||||  .|  .|  |||.|||||||| |.||  ..||||||||| .|||||.|| ||||
KFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIYSFGRVPYPR

MSQKDVVDALPKGYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTL
.. |||| .  |||||| |. ||.  |. ||. ||...|  |||| ...  |
IPLKDVVKHVEKGYRMEAPEGCPPHVYK-VMKQCWHLNPAKRPTFRQVREQL
Kinase Csk.AA TyrKc 194-442 38 5.5e-127 429.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-280/280
Sequence Identity: 38% (110 aa)

LIKGAKLGSGQFGDVFEGTYCGQRVAIKTLKNYEQSLRDEFLAEASVMTKL--KHPNLVKLEGVVTEG-------KEIMLVTEYMAKGNLLDFLRSRGRS
. .| |||.|.|| |..||.  . ||.|.||..    | .|. ||..|.||  .|||.|.| ||.|..       . .|.|.|||..|.|.|.||.... 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

VVKKDLLFKFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAKRSDWG-------DIDS------GK--LPIKWTAPEVLKHKVSTSKSD
 .. . | .|  .|..||..|...|..||||||||.|..|. ..|..||||..  . .       |  .      ||  |||.|.|||...... |.|||
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGITMWEIYSYGRSPYPR-----MSQKDVVDALPKGYRMERPDD--------CPETLYTAVMRACWEMDPLSRPTFNRLKRTL
|||||..||||..|| .|||      || ..|.  . .||||..|..        ||. .|. .|. ||. || .||||. ... .
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase Csk.AA Pkinase_Tyr 194-442 43 2.2e-126 428.64 Pfam 1-270 (270) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-270/270
Sequence Identity: 43% (117 aa)

LIKGAKLGSGQFGDVFEGTYC------GQRVAIKTLKNYEQSL---RDEFLAEASVMTKL-KHPNLVKLEGVVT-EGKE--IMLVTEYMAKGNLLDFLRS
...| |||.|.||.|..||.       .. ||.|.||..  .    |..|..||..|..| .|||.|.| ||.| .|.   |..|.|||..|.|||.||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---GRSVVKKDLLFKFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAKRSDWGDID-----SGKLPIKWTAPEVLKHKVSTSKSDVWS
.   ....  || | .. ..|..||..|| .| .||||||||.|..|. |.|..|||||.     |       .|||||||.|||...... |.||||||
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGITMWEIYSYGRSP-YPRMSQKDVVDAL-PKGYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTL
||..||||..||..| || ||  .|....  .||||..|..||. .|.  |. ||. ||  ||||  . . |
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase Csk.AA TK 194-442 23 3e-116 391.38 In-house 1-486 (486) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-486/486
Sequence Identity: 23% (116 aa)

LIKGAKLGSGQFG---DVFEGTYCG---------------------------QRVAIKTLKNY-EQSLRD-------------EFLAEASVMTKLK----
.. | |||.||||   .|..|.. |                           ..||.|.||   ..| ..             .||.||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVKLEGVVTEG------------KEIMLVTEYMAKGN----LLDFLRSRG----------------------------------------------
 |||.|.| ||.|.|            . .|.|.|||..|.    |.|.||..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------RSVVKKDLLFKFTQDICEGMAFLEKQ------NVVHRDLAARNVLISEEDV-----------AKVADFGLAK
                            .. .    |  . ..|..||..|...      |.|||||||||.|..|..|           .|.|||||..
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RSDWGDID-------------------------------SGKLPIKWTAPEVLKHKV---------STSKSDVWSFGITMWEIYSYGRSPYPR-M
     ..   . |                               .|||||.|.|||.|...|          |.||||||||..||||..||. ||.  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SQ---------KDVVDALPKG--------------YRMERPDDCPE-------------TLYTAVMRACWEMDPLSRPTFNRLKRTL
|          ..|.. | .|              .||..|..||.             ..|  .|. ||. ||  ||||  |.. |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Csk.AA Src 194-442 45 3.8e-109 368.91 In-house 1-255 (255) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-255/255
Sequence Identity: 45% (117 aa)

LIKGAKLGSGQFGDVFEGTYCG-QRVAIKTLKNYEQSLRDEFLAEASVMTKLKHPNLVKLEGVVTEGKEIMLVTEYMAKGNLLDFLR-SRGRSVVKKDLL
.    |||.||||.|..|.. |   ||.||||       . ||.|| .|.||.|..||.|  |..... |  |||||..|.|||.|. ..  . ..   |
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT-MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQL

FKFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAKRSDWGD-----IDSGKLPIKWTAPEVLKHKVSTSKSDVWSFGITMWEIYSYGRS
  ..  . ||||.||..|..||||||||||..|. |.||||||||.  . .|         |.|||||||| . . . | ||||||||| ..|| .||| 
IDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYPRMSQKDVVDALPKGYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTL
||| |. ..|.... .|||| .|. ||. ||  .|. ||. ||  |||| .|   |
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Csk.AA SFK-Src 198-446 46 4.7e-108 321.39 In-house 5-259 (259) Show / Hide 
Range on Protein: 198-446
Range on HMM: 5-259/259
Sequence Identity: 46% (121 aa)

AKLGSGQFGDVFEGTYCGQ-RVAIKTLKNYEQSLRDEFLAEASVMTKLKHPNLVKLEGVVTEGKEIMLVTEYMAKGNLLDFLRS-RGRSVVKKDLLFKFT
 ||||||||||. |.  ..  ||.||||    |  .|||.|| || ||.||||..|  | | |  |  .|| |. | |||.|.. .|||  .  .|   .
KKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMS-AEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRS-LRMPQLVDMA

QDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAKRSDWGDI-----DSGKLPIKWTAPEVLKHKVSTSKSDVWSFGITMWEIYSYGRSPYPR
 ..  |||.|| || |||||||||||. .  | ||.|||..      |.     .  | ||||||||  .      ||||||||| | ||  ||| ||| 
AQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPG

MSQKDVVDALPK--GYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTLAKFK
|. . |.  . .  ||||. |  ||. .| ..|..||   |  ||||  ||  .  | 
MTNMEVLQQVDRPEGYRMPCPPNCPDEYY-KIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase Csk.AA UTK 194-442 34 3.2e-100 339.25 In-house 1-296 (296) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-296/296
Sequence Identity: 34% (101 aa)

LIKGAKLGSGQFGDVFEGTY--CG-----QRVAIKTLKNYEQSLRD-----EFLAEAS---VMTKLK-HPNLVKLEGVVTEGKEIMLVTEYMAKGNLLDF
.. |..||.|.||.|.....  |      ..||.|.... . . ..     .|. ||    .| ... |||...| ||.| .. .|.|||||..|.|...
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRSRGRSV------VKKDLLFKFTQDICEGMAFLEKQNVVHRDLAARNVLISEE-------DVAKVADFG---LAKRSD--------WGD-----IDSGK
||. ....      .... . ..  || .||..|. ...|||||||||.|. .         |.|.||||   ...|          |..      . ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPIKWTAPEVLKHK-VSTSKSDVWSFGITMWEIYSYGRSPYPRMSQKDVVDALPKG--YRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTL
.||.|.|||.| |    |.||||||||...|||...|| ||| ||  .|. .. .|  |||..|.|||...|. .|..||..||  ||.| .|  ..
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYR-LMHRCWHYDPQERPDFEDLVQQM
Kinase Csk.AA TK-Unique 194-442 35 7.1e-98 331.46 In-house 1-294 (294) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-294/294
Sequence Identity: 35% (104 aa)

LIKGAKLGSGQFGDVFEGTYCG--------QRVAIKTLK-NYEQSLRDEFLAEASVMTKLK-HPNLVKLEGVVTEGK-EIMLVTEYMAKGNLLDFLRSRG
|  | ..|.|.|| |. |...|        ..||.|.|| |  .  ...|| |...| .|. |||.|...|. |.     |.. ||...|||...||...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

R------------------------SVVKKDLLFKFTQDICEGMAFLEK--QNVVHRDLAARNVLISEEDVAKVADFGLAK----RSDWGDIDS-GKLPI
.                        . ..  .|. |  .|. ||..|..  ...|||||.|||||..|  |.|..|||.|.    . .   ..| |..||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWTAPEVLK--HKVS-TSKSDVWSFGITMWEIYSYGRSPYPRMSQKDVVDALPKGYRMERPDDC-PETLYTAVMRACWEMDPLSRPTFNRLKRTL
.| |||.||  |..  |.||||||||..|||| ..|  |||.|..||.......||||..|. | ....|  .|. ||  .| .||.|  .|  |
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMY-NLMKSCWQWEPEERPSFRQIKHRL
Kinase Csk.AA SFK-Abl 194-442 47 1.2e-96 315.94 In-house 1-251 (251) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-251/251
Sequence Identity: 47% (119 aa)

LIKGAKLGSGQFGDVFEGTYCGQRVAIKTLKNYEQSLRDEFLAEASVMTKLKHPNLVKLEGVVTEGKEIMLVTEYMAKGNLLDFLRS-RGRSVVKKDLLF
 | |  || ||.| |. | .  .|||||| |. |     .|. || .| ...|||||.| || | .  .  |.|.|  |||||.|.| ..|  .    . 
IILGHRLGEGQYGEVYKGIWNNHRVAIKTIKD-ESMETKDFMKEAHIMKRMQHPNLVRLIGVCTREGPMYIVQEFMNYGNLLDYLQSPQSRIQIDHVSMM

KFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAK--RSDWGDIDSG-KLPIKWTAPEVLKHKVSTSKSDVWSFGITMWEIYSYGRSPYP
   | | .|| ||| |. .|||||||| |. .    ||||||.|    ||  .   | |.|||||||| |   . | ||||||||||.|||  ||  |||
HCAQQIADGMSFLEEQHFIHRDLAARNCLVGDNLQIKVADFGMARFVDSDFYEARIGTKMPIKWTAPESLCYDIFTIKSDVWSFGITLWEIATYGDVPYP

RMSQKDVVDALPKGYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTL
 .  .||.. |  |||| ||.|||  .|  .|  ||...|  || |  |.. |
GIHHRDVINQLMMGYRMQRPQDCPMEIY-NIMTQCWDVNPDERPSFHDLQHQL
Kinase Csk.AA Tec 200-444 44 6.5e-95 321.62 In-house 7-254 (254) Show / Hide 
Range on Protein: 200-444
Range on HMM: 7-254/254
Sequence Identity: 44% (112 aa)

LGSGQFGDVFEGTYCGQR-VAIKTLKNYEQSL-RDEFLAEASVMTKLKHPNLVKLEGVVTEGKEIMLVTEYMAKGNLLDFLRSRGRSVVKKD-LLFKFTQ
||||||| |  | . .|. ||||..|  | |   ..|. || ||.|| ||.||.| || .. . | .|||||..| ||..||...    |.  .| . .|
LGSGQFGVVHLGKWRHQYDVAIKMIK--EGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILLEMCQ

DICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAKRS-DWGDIDSG--KLPIKWTAPEVLKHKVSTSKSDVWSFGITMWEIYSYGRSPYPRMSQ
|.|||||.||.....|||||||| |.... | ||.|||..    |   . |.  | |.|| .|||..     ||||||.||. |||..| |. ||..|| 
DVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSN

KDVVDALPKGYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTLAK
 .||..  .|.|..||. |....|. .|  ||.  |  ||||..| |....
SEVVEHVSQGHRLYRPHLCSMHIYQ-IMYHCWHEKPEERPTFQQLLRQITE
Kinase Csk.AA Abl 194-442 45 6.9e-91 303.43 In-house 1-252 (252) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-252/252
Sequence Identity: 45% (116 aa)

LIKGAKLGSGQFGDVFEGTY--CGQRVAIKTLKNYEQSLRDEFLAEASVMTKLKHPNLVKLEGVVTEGKEIMLVTEYMAKGNLLDFLRSRGRSVVKKDLL
..   ||| ||.|.|.|| .   .. ||.||||     . .|||.|| .| ..||||||.| || |      ..||.|..|||||.||. .|. ..   |
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEV-HEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVL

FKFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAK--RSDWGDIDSG-KLPIKWTAPEVLKHKVSTSKSDVWSFGITMWEIYSYGRSPY
      |  || .|||.. .|||||||| |..|... ||||||||.  . |      | | |||||||| | ..   |||||| ||. .|||  || |||
LYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

PRMSQKDVVDALPKGYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTL
| .  ..| . | ||||||||. ||.  |  .||.||. ..  ||.|. . ...
PGIDLSHVYHKLEKGYRMERPEGCPPKVY-ELMRQCWQWSHTDRPSFKEIHHAM
Kinase Csk.AA SrcB 194-443 48 2.4e-90 305.85 In-house 1-251 (251) Show / Hide 
Range on Protein: 194-443
Range on HMM: 1-251/251
Sequence Identity: 48% (122 aa)

LIKGAKLGSGQFGDVFEGTYCGQ-RVAIKTLKNYEQSLRDEFLAEASVMTKLKHPNLVKLEGVVTEGKEIMLVTEYMAKGNLLDFLRSRGRSVVKKDLLF
|    |||.||||.|. |.| .. .||.||.|.   |  . ||||| || .|.|  ||.|  |||    | ..||||||| |||||..   | .. . | 
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSP-EAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLI

KFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAKRSDW---GDIDSGKLPIKWTAPEVLKHKVSTSKSDVWSFGITMWEIYSYGRSPYP
 ..  | ||||..|..| .|||| | |.|.||  . |.||||||.  .       .  | |||||||| ... . | ||||||||| . ||  ||| |||
DMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

RMSQKDVVDALPKGYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKRTLA
 |.  .|. .| .|||| ||| ||| ||  .|. ||   |  ||||. |.  | 
GMTNPEVIRNLERGYRMPRPDNCPEELYN-IMMMCWKERPEERPTFDYLQSVLD
Kinase Csk.AA S_TKc 194-446 24 2.9e-52 180.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 194-446
Range on HMM: 1-231/231
Sequence Identity: 24% (65 aa)

LIKGAKLGSGQFGDVFEGTYCG--QRVAIKTLKNYEQSLRDEFLAEASVMTKLKHPNLVKLEGVVTEGKEIMLVTEYMAK--GNLLDFLRSRGR----SV
  .. |.|.| || |. ..  .  ..|||| .|       . .. | ... | .|||.||| .|  . ... .|.||.    |.|.|....|||    ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

VKKDLLFKFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVAKVADFGLAKRSDWGDIDSGKLPIKWTAPEVLKHKVSTSKSDVWSFGITMWEIYSYGR
       .... ||...... .....||||   |.|..|  . |..|||||..      ..      . |||||  . .. |.|.||.|....| .. |.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLC-GY

SPYPRMSQKDVVDALPKGYRMERPDDCPETLYTAVMRACWEMDPLSRPTFNRLKR-----TLAKFK
 |.|   .. . . .            .. .    .| |...||  |||   . .      .  . 
PPFP--QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Csk.AA Pkinase 194-442 22 5.7e-43 153.02 Pfam 1-293 (293) Show / Hide 
Range on Protein: 194-442
Range on HMM: 1-293/293
Sequence Identity: 22% (67 aa)

LIKGAKLGSGQFGDVFEGTYCGQR--VAIKTLKNYEQSL--RDEFLA--EASVMTKLKHPNLVKLEGVVTEGKEIMLVTEYMAKG----NLLDFLR-SRG
. .| |.||| || |....  | .  ||.|..|  ...   . . .   |...| .|.||| |.| ........| .|.||. .|     | |... .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RSV-VKKDLLFKFTQDICEGMAFLEKQNVVHRDLAARNVLISEEDVA----KVADFGLAK---RSDWGDIDSGKLPIKWTAPEVLK-HKVSTSKSDVWSF
...    . . ..   |..|.... .....||||   |.||.....     |..||||||       .  ..    . . ||||.. ..  ..|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITMWEIYSYGRSPYP--------RMSQKDVVDALPKGYRMERPDDCPE-----------------TLYTAVMRACWEMDPLSRPTFNRLKRT--L
|....| .. || |.|        .. |. . .  |.  . .  ....                       ... |...|| .|||.  ..    .
GCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF