Gene TK2 (Sea Urchin)

TK2

Species: Sea Urchin
Alias: SPU_005055, TK2, Spk270
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: TK-Sp1

Sequence

Name Sequence Type Origin Length Description Download
TK2.AA Protein None 379 None Fasta, JSON
TK2.kin_dom Protein Kinase Domain None 219 None Fasta, JSON

Protein domain

Protein domains of TK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TK2.AA TK-Sp1 3-234 77 7.1e-198 663.66 In-house 38-270 (270) Show / Hide 
Range on Protein: 3-234
Range on HMM: 38-270/270
Sequence Identity: 77% (180 aa)

RENATRSMKEDFLEEIKLIVEIGNHPNILPILGCCTADEPHYLITELMDYGDLLHFLWKCREEKNAVNDPIYKLTPTGQLQIAIQIARGMEYLSTTLYYH
| |||  ||||||.||||..|.|.||.||.|.||||..||||.|||.|.|||||||||||||.|....||||.||.|.|.||..||||||||.|.|.|||
RVNATPGMKEDFLNEIKLMFELGQHPHILQIIGCCTVHEPHYMITEMMKYGDLLHFLWKCREDKHIRQDPIYDLTDTQQYQICRQIARGMEYISKTRYYH

GDLAARNVLVGKGLICKISDFGLADDIYQRGYKRLAPERKRPVKWVSLETNTQGKCSIQSDVWSFGIVLYEIYTLGGVPYPGMDGRYVISKLQQGYRMER
||||||||||||||.|||||||||||||||||||||||||||||||||||||||||.|||||||||||.|||||.||.||||||||.||||||.|||||.
GDLAARNVLVGKGLMCKISDFGLADDIYQRGYKRLAPERKRPVKWVSLETNTQGKCTIQSDVWSFGIVMYEIYTNGGMPYPGMDGREVISKLQDGYRMEK

TSTCPEE-YEIMRSCWHEHSHHRPTFTVMYNTL
...|||. |..||.|||||.||||||. ..| .
PDNCPEDVYDMMRACWHEHPHHRPTFKNIFNFF
Pkinase_Tyr TK2.AA Pkinase_Tyr 1-234 41 3.6e-94 319.57 Pfam 35-270 (270) Show / Hide 
Range on Protein: 1-234
Range on HMM: 35-270/270
Sequence Identity: 41% (102 aa)

MSRENATRSM--KEDFLEEIKLIVEIGNHPNILPILGCCT-ADEP--HYLITELMDYGDLLHFLWKCREEKNAVNDPIYKLTPTGQLQIAIQIARGMEYL
| .|.|. .   .|||..|.|.  ..|.||||.  .|.||  .||  .|...|.| .||||..| | |       ..  .||.   ||...|||.|||||
MLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR-------EDKQPLTMKDLLQMCWQIAKGMEYL

STTLYYHGDLAARNVLVGKGLICKISDFGLADDIYQRGYK-RLAPERKRPVKWVSLETNTQGKCSIQSDVWSFGIVLYEIYTLGGVP-YPGMDGRYVISK
.   . | ||||||.||......||.||||| |||  .|  | . . | |.|| ..|    ||....|||||||....||.|.|. | ||||.   |. .
ESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEY

L-QQGYRMERTSTCPEE-YEIMRSCWHEHSHHRPTFTVMYNTL
. ..||||..   ||.| |..|..|||.   .||||.  .. |
IYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase TK2.AA TK 1-234 23 6.6e-89 298.12 In-house 59-486 (486) Show / Hide 
Range on Protein: 1-234
Range on HMM: 59-486/486
Sequence Identity: 23% (100 aa)

MSRENATRSMKEDFL----------------EEIKLIVE-IGNHPNILPILGCCTAD------------EPHYLITELMDYGD----LLHFLWKCREEKN
| .| .. |..| |.                ||.|.  . .|.||||. ..|.|| .            || ....|.|..||    |...|.|||....
MLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQ

AVNDPIY---------------------------------------------KLTPTGQLQ-------------------IAIQIARGMEYLSTT-----
   | ..                                              || . .||                   .. |||.|||||.       
HEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFI

-LYYHGDLAARNVLVGKGLI-----------CKISDFG--------LADDIYQRGYKRLAP------------------------ERKRPVKWVSLETNT
  . |.||||||.|||....           |||.|||        || |||.... . .                          .| |..| . |. .
QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLN

---------QGKCSIQSDVWSFGIVLYEIYTLG-GVPYPGMDG---------RYVISKLQQG--------------YRMERTSTCP--------------
          ||....|||||||....||.|.| . .|.||.          . |. .|..|              .||..   ||              
DRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPP

EEY-EIMRSCWHEHSHHRPTFTVMYNTL
||| ..|..|||.   .||||. ... |
EEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase TK2.AA TK-Unique 1-234 36 2.8e-84 286.28 In-house 37-294 (294) Show / Hide 
Range on Protein: 1-234
Range on HMM: 37-294/294
Sequence Identity: 36% (95 aa)

MSRENATRSMKEDFLEEIKLIVEIGNHPNILPILGCCTAD-EPHYLITELMDYGDLLHFLWKCREEKNAV---------------NDPIYKLTPTGQLQI
| ..|||   | ||| ||..  |.| ||||. .||||| . ||...| | . .|.|.|.|..|| ..  .                .. . ..|   ...
MLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHF

AIQIARGMEYLSTTLY--YHGDLAARNVLVGKGLICKISDFGLADDIYQ-RGYKRLAPERKRPVKWVSLETNT--QGKC-SIQSDVWSFGIVLYEIYTLG
|.|||.|||||.  ..   |.||.|||||.. ...|||.|||.|.|.|  . | .   . . |..| ..|     .| . ...|||||||....|| |||
AWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLG

GVPYPGMDGRYVISKLQQGYRMERTSTC--PEEYEIMRSCWHEHSHHRPTFTVMYNTL
. |||||. . .. ....||||.. . |  .| |..|.|||..  ..||.|.   . |
ACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase TK2.AA TyrKc 1-234 33 8.8e-80 272.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-234
Range on HMM: 1-280/280
Sequence Identity: 33% (99 aa)

MS---------------------------RENATRSMKEDFLEEIKLIVEIG-NHPNILPILGCCTAD-------EPHYLITELMDYGDLLHFLWKCREE
 .                           .|.|    .|||..|...  ..| .||||. ..|.|| .       ||.....|.|..|||...| |.|..
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

KNAVNDPIYKLTPTGQLQIAIQIARGMEYLSTTLYYHGDLAARNVLVGKGLICKISDFGLADDIYQR-------GYKRLA--PERK--RPVKWVSLETNT
          |..   |....|||.|||||.   . | ||||||.|||.....|||||||. |||          |.| .    .|   |..| ..|.  
----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

QGKCSIQSDVWSFGIVLYEIYTLGGVPYPG-----MDGRYVISKLQQGYRMERTST--------CPEE-YEIMRSCWHEHSHHRPTFTVMYNTL
 ||....|||||||....||.|.|. ||||     |. . || ...|||||..           ||.| |.||..||||  . ||||.  .  .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TK2.AA Src 12-234 40 3.7e-74 251.33 In-house 39-255 (255) Show / Hide 
Range on Protein: 12-234
Range on HMM: 39-255/255
Sequence Identity: 40% (93 aa)

EDFLEEIKLIVEIGNHPNILPILGCCTADEPHYLITELMDYGDLLHFLWKCREEKNAVNDPIYKLTPTGQLQIAIQIARGMEYLSTTLYYHGDLAARNVL
|.||.|...  .   |.... ..  |. .|| | .||.|  | || .| |        ..   .|  . .. .| |.|.||.||.   | | ||||||||
EAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK--------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVL

VGKGLICKISDFGLA------DDIYQRGYKRLAPERKRPVKWVSLETNTQGKCSIQSDVWSFGIVLYEIYTLGGVPYPGMDGRYVISKLQQGYRMERTST
||....||. |||||      ||.|         . | |.||   |  . |. .| |||||||| |.|| | | ||||||. . |. ....|||| . ..
VGENNVCKVADFGLARLIKEDDDEYCARH-----GAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN

CPEE-YE-IMRSCWHEHSHHRPTFTVMYNTL
||.| || ||. |||.    ||||  ... |
CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase TK2.AA UTK 2-234 32 2.4e-65 222.51 In-house 39-296 (296) Show / Hide 
Range on Protein: 2-234
Range on HMM: 39-296/296
Sequence Identity: 32% (85 aa)

SRENATRSMK--EDFLEEIK---LIVEIGNHPNILPILGCCTADEPHYLITELMDYGDLLHFLWKCREEKNAVNDPIYKLTPTGQLQIAIQIARGMEYLS
....|....    ||.|| .   .      |||.|  .| ||..|| ...||.|  |||...| ..|.. .   ..   || . .|. | .|||||.||.
HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPP---ACPHWLTLHQRLCMAWDIARGMQYLH

TTLYYHGDLAARNVLVGKG-------LICKISDFG---LADDIY---------QRGYKRLAPERKRPVKWVSLETNTQG-KCSIQSDVWSFGIVLYEIYT
.  . |.||||||.||..        ..|||.|||   .. ...         .  | . .. .. |..| . |  |.. . ...|||||||.|..||.|
SCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWT

LGGVPYPGMDGRYVISKLQQG--YRMERTSTCPEE-YEIMRSCWHEHSHHRPTFTVMYNTL
 | .|||||  . |.  .  |  |||..   ||.. |..|..|||     ||.|  .. ..
WGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase TK2.AA Abl 12-234 42 4.8e-62 205.59 In-house 40-252 (252) Show / Hide 
Range on Protein: 12-234
Range on HMM: 40-252/252
Sequence Identity: 42% (96 aa)

EDFLEEIKLIVEIGNHPNILPILGCCTADEPHYLITELMDYGDLLHFLWKCREEKNAVNDPIYKLTPTGQLQIAIQIARGMEYLSTTLYYHGDLAARNVL
..||.|  .. |.  |||.  .|| || . | |.||| | || || .| .| .|         .|..   |..| ||| ||.||    . | |||||| |
HEFLKEAAIMKEM-KHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDRE---------ELPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCL

VGKGLICKISDFGLADDIYQRGYKRLAPERKRPVKWVSLETNTQGKCSIQSDVWSFGIVLYEIYTLGGVPYPGMDGRYVISKLQQGYRMERTSTCPEE-Y
||   | |. |||||  . .  |   |   | |.||   |     | |..|||| ||..|.|| | |  ||||.|   |  ||..||||||   ||.. |
VGEHHIVKVADFGLARMMKDDTYTAHA-GAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVY

EIMRSCWHEHSHHRPTFTVMYNTL
|.|| ||. .   ||.|. . ...
ELMRQCWQWSHTDRPSFKEIHHAM
Kinase TK2.AA Frk 12-238 40 5.3e-61 208.98 In-house 39-260 (260) Show / Hide 
Range on Protein: 12-238
Range on HMM: 39-260/260
Sequence Identity: 40% (93 aa)

EDFLEEIKLIVEIGNHPNILPILGCCTADEPHYLITELMDYGDLLHFLWKCREEKNAVNDPIYKLTPTGQLQIAIQIARGMEYLSTTLYYHGDLAARNVL
.||| | ... ..  || .. .   || .|| |.|||||  | |...|        |.||   ..  . ....| |.| || ||    | | ||||||||
NDFLREAQIMKKL-RHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYL-------QAINDKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVL

VGKGLICKISDFGLADDIYQRGY--KRLAPERKRPVKWVSLETNTQGKCSIQSDVWSFGIVLYEIYTLGGVPYPGMDGRYVISKLQQGYRMERTSTCPEE
||...|||| |||||  . .          . . |.||   |     | .|.||||||||.|.|| | | .||||| .. |.  ...|||| . . ||..
VGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQ

-YEIMRSCWHEHSHHRPTFTVMYNTLDAML
 ||||  |||.....||||  .   |.  .
LYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase TK2.AA KIN6 11-234 34 3.5e-60 197.51 In-house 61-305 (305) Show / Hide 
Range on Protein: 11-234
Range on HMM: 61-305/305
Sequence Identity: 34% (88 aa)

KEDFLEEIKLIVEIGNHPNILPILGCCTADEPHYLITELMDYGDLLHFLW-KC----------------REEKNAVN---DPIYKLTPTGQLQIAIQIAR
. ||. || .    | || .   ||| |  .. .|. |. . .|||..|  .|                 |  . .    ...  |     ...| ||. 
HHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYCCHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHKDL-----YMFAWQICD

GMEYLSTTLYYHGDLAARNVLVGKGL---ICKISDFGLAD--DIYQRGYKRLAPERKR--PVKWVSLETNTQGKCSIQSDVWSFGIVLYEIYTLGGVPYP
|||||.     | ||||||||| .|.    ||||||||.   .  | .|. ..    |  |.|| ..|     . |. |||||||....|...||.||||
GMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKG---GRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYP

GMD-GRYVISKLQQGYRMERTSTCPEE-YEIMRSCWHEHSHHRPTFTVMYNTL
.|     .|  .  | |..    |||| |.||.||| | .  || |. | . .
EMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase TK2.AA FGFR 24-234 38 2e-59 201.22 In-house 61-293 (293) Show / Hide 
Range on Protein: 24-234
Range on HMM: 61-293/293
Sequence Identity: 38% (89 aa)

IGNHPNILPILGCCTADEPHYLITELMDYGDLLHFLWKCR-EEKNAVNDPI-----YKLTPTGQ--------------LQIAIQIARGMEYLSTTLYYHG
|| |.||.  ||||| . | | | |.   | |  || . |  .. .  |.        ..|..|               ..| |.|||||||      | 
IGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARRPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHR

DLAARNVLVGKGLICKISDFGLADDIYQRGYKRLAPERKRPVKWVSLETNTQGKCSIQSDVWSFGIVLYEIYTLGGVPYPGMD-GRYVISKLQQGYRMER
|||||||||. . . ||.||||| || .  | |   .   |.||  .|     .   ||||||.|. | || |.|| |||.        . |. |.|||.
DLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEK

TSTCPEE-YEIMRSCWHEHSHHRPTFTVMYNTL
 . |..| | .|..|||. .  ||||. .   |
PHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase TK2.AA Src-Unclassified 12-234 37 6.1e-59 200.73 In-house 42-284 (284) Show / Hide 
Range on Protein: 12-234
Range on HMM: 42-284/284
Sequence Identity: 37% (96 aa)

EDFL--------EEIKLIVEIGNHPNILPILGCCTADEPHYLITELMDYGDLLHFLWKCREEKNAVNDPIYKL-TPTGQ------LQIAIQIARGMEYLS
| ||        .| ..  .   |.|.   .. |. .|| | |||.|  | || .|   ||       .|  .   ||         || |.|.||.||.
EAFLHVKILNFCQEAQIMKKC-RHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWL---REGGGQYL-HIQDMSEETGRKNVLIGVDIAAQVASGMMYLE

TTLYYHGDLAARNVLVGKGL-----ICKISDFGLA------DDIYQRGYKRLAPERKRPVKWVSLETNTQGKCSIQSDVWSFGIVLYEIYTLGGVPYPGM
   | | ||||||||.|        . |. |||||      ||.|    .. |   . |.||   |  . |. || |||||.|| |.|| |.| .|||||
SKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYC--MRTGA---MFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMTKGQTPYPGM

DGRYVISKLQQGYRMERT--STCPEE-YE-IMRSCWHEHSHHRPTFTVMYNTL
. | |.  .  |||| .     ||.  || ||  |||.    ||||   |. .
HNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase TK2.AA S_TKc 3-238 20 5.8e-12 -1.49 SMART 19-231 (231) Show / Hide 
Range on Protein: 3-238
Range on HMM: 19-231/231
Sequence Identity: 20% (52 aa)

RENA---------TRSMKEDFLEEIKLIVEIGNHPNILPILGCCTADEPHYLITELMDY--GDLLHFLWKCREEKNAVNDPIYKLTPTGQLQIAIQIARG
|..           .   |... ||..  .  .||||  .....   .  |...|..|   |||.... |.. ...      .....     .. ||...
RHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR-----FPFPE-HARFYMYQICCA

MEYLSTTLYYHGDLAARNVLVGKGLICKISDFGLADDIYQRGYKR------LAPERKRPVKWVSLETNTQGKCSI-QSDVWSFGIVLYEIYTLGGVPYPG
.||.      | ||   |.|. .    ||.|||||  .    .        .|||                . .   .|.||.|..||| .. |  |.| 
LEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL--------------GYGKCKCDWWSCGCILYEMLC-GYPPFP-

MDGRYVISKLQQGYRMERTSTCPEEYEIMRSCWHEHSHHRPTFTVMYN-----TLDAML
    ... |.            ||  ...| |..    .|||     .      ..  .
--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TK2.AA Pkinase 8-95 21 2.7e-05 19.8 Pfam 35-124 (293) Show / Hide 
Range on Protein: 8-95
Range on HMM: 35-124/293
Sequence Identity: 21% (21 aa)

RSMKEDFLE------EIKLIVEIGNHPNILPILGCCTADEPHYLITELMDYG----DLLHFLWKCREEKNAVNDPIYKLTPTGQLQIAIQIARGMEYL
|. |.....      ||..  .. |||||. ...... .   |...|... |    || ...          . ..| ...     .. ||.||.||.
RHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST------WRHGCFY-FSEWECKFYMYQILRGLEYC
Kinase TK2.AA Pkinase 162-234 17 4.7e-05 18.94 Pfam 193-293 (293) Show / Hide 
Range on Protein: 162-234
Range on HMM: 193-293/293
Sequence Identity: 17% (18 aa)

SDVWSFGIVLYEIYTLGGVPYPGM------DGRYVISKLQQGYRMERTSTC---------------------PEEYEIMRSCWHEHSHHRPTFTVMYNT-
.|.||.|..||| .. |  |.||       | ...| .  ..  ..  ..                      .|  .....|..   . |||..   .  
VDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

-L
 .
WF
Kinase TK2.AA Pkinase 109-126 40 1.006679 3.64 Pfam 138-159 (293) Show / Hide 
Range on Protein: 109-126
Range on HMM: 138-159/293
Sequence Identity: 40% (9 aa)

NVLVGKGLIC----KISDFGLA
|.|. .   .    ||.|||||
NILIDNNGHIDACVKICDFGLA