Gene ILGFR (Sea Urchin)

ILGFR

Species: Sea Urchin
Alias: Spk274, SPU_002840, ILGFR
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: InsR

Sequence

Name Sequence Type Origin Length Description Download
ILGFR.AA Protein None 1221 None Fasta, JSON
ILGFR.kin_dom Protein Kinase Domain None 280 None Fasta, JSON

Protein domain

Protein domains of ILGFR.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor ILGFR.AA ANF_receptor 175-542 21 3.2e-52 184.62 Pfam 1-355 (364) Show / Hide 
Range on Protein: 175-542
Range on HMM: 1-355/364
Sequence Identity: 21% (86 aa)

GIEPGARMAIDAVNADLN-ILPNYKLTLASMETG---CSPETSLLSYFKFYEDRGQSLAGLVGPMCSSEAEVVGSVSRFLNTVVVSYQSDSPSLSN--KD
  .|..||||. .||| . .||...|..   ..    ..     .  .... ..    ....|| ||.... |... . .|  ..|. ...|.|..  |.
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KG---VVAIIGPSCSYVCIPVARIANHWNIPMISWGCTCPCLTDKAKN

QYPYYFRTFPDTTEQ-CYALIELFQN-FGWGRYALLSDSEDI--TYKV---MKNMEEVMIE-GGIEMVV--DIYMATNEVNQAAVTSYLEEIVSKKAHII
.|||.||| |. | |  .|.....|  ||| . |.. |..|      .   |. ..... | ||.   .     . ... ....  . . .|...||..|
RYPYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVI

VGYFPENVA----RLVLCEAHKQGLTGEKGYQWFLPEWYQDAWWDTDYHNKNSPSYSIFSTSPSSFNISCTTTEMMQAIKGYISLS-------RAYIANW
|  .... .    |.....||..|. .. ||.|.. .|. .... . .                 .  .  ... ..|.|| . .        . .. .|
VMCCYPDDMGLLQRQIMQQAHELGM-MSGGYVWIYTDWWMHSYDMQ-W----------------WYDDDMDNDKFREAMKGVLGFTMHPSPEFQEFMQRW

DKPVPGHETVEGWINEYNSLIEKEGKMPSTYAAYAYDTVWTYAYALDKLLFNDVAALDTLSSQQTIRTY---------LRHLSN-TSFSGVTGEVKFMD-
 |                     ..  ...||||||| |. ||.||...| .| .. . ..       .         |... | ..| ||||.|.| | 
KK---------------------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGC-------DIMKWHGWQLLHYMWNKVNFEGVTGDVQFDDN

QDRRGP
 .|| .
GGRRPD
Kinase ILGFR.AA InsR 675-945 53 1.3e-204 686.08 In-house 1-278 (278) Show / Hide 
Range on Protein: 675-945
Range on HMM: 1-278/278
Sequence Identity: 53% (149 aa)

VVLNRKLGEGAFGTVYGG--EALLDDNKWA--AVAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGRRH
.||.|..|.|.||.||.|  .....|..|.  ..|.||....||..|...||.||.|||.||....|.|||||.||.|||.|||.|.|||||..|..||.
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

LVG--EGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYDSDYYRLGKRSKLPVRWMAPESLTEGIFTT
...  .....|||||.|.||...|...|..|..|||....||||||||||.|....|||||||||||..|..||||.|....|||||||||||..|.|||
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTT

MSDVWSLGVVIYEVVTFGSFPYQELSNAEVLDYI-RNRNSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDVNDILCQ
.|||||.|||..|.||.|..|||.|||..||.|| ...|.|||||.|......|||.||..||..|||..|....||.
HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase ILGFR.AA Pkinase_Tyr 675-943 44 1.5e-129 439.34 Pfam 1-270 (270) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-270/270
Sequence Identity: 44% (124 aa)

VVLNRKLGEGAFGTVYGGEAL-LDDNKWAAVAVKTLKLGASVEE--KLDFLSEAEVMKRF-NHKNIVNLLGVCT-RGEP--MYAVMEFMLYGDLKTFLLG
.....||||||||.|| |..  ..||.   ||||.|| ||. |.  . ||..||..|| . .|.|||.|.|||| .|||  .| |||.| .|||...|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

RRHLVGEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYDSDYY-RLGKRSKLPVRWMAPESLTEGIF
.|          ...  .. .| .|  .||.|..||.|.|..|||||.|||||. . .|||.|||..|..|. ||| | .. .|||..|||||.. .|.|
HR---------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKF

TTMSDVWSLGVVIYEVVTFGSFP-YQELSNAEVLDYI-RNRNSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDVNDIL
|| ||||| ||...|..|.|  | |...||.||..|| .... . .||.|.. .  ||.|||. .|..||| ...  .|
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase ILGFR.AA TyrKc 675-943 39 7.6e-128 431.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-280/280
Sequence Identity: 39% (119 aa)

VVLNRKLGEGAFGTVYGGEALLDDNKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRF--NHKNIVNLLGVCTRG-------EPMYAVMEFMLYGDLKTFL
..|..||||||||.|| |..         ||||.|| .|    . ||..||..|...  .|.|||.|.|||| .       ||.. |||.| .|||| .|
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

LGRRHLVGEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYDS-------DYYRL----GKRSKLPVR
  .|.              |...| |.  .||.| .||.| |..|||||.|||||.. .||||.|||..|..||        ||||     |... ||.|
RKHRPK------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR

WMAPESLTEGIFTTMSDVWSLGVVIYEVVTFGSFPYQE-----LSNAEVLDYIRNRNSLRPPEG--------CSPALGALMMQCWAIQPQHRPTAKDVND
|||||.. .|.||| ||||| ||...|. |.|  || .     .||.||. |..... ...|.         |....  .| |||. .|  ||| ... .
WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

IL
..
CF
Kinase ILGFR.AA TK 675-943 25 2e-115 388.62 In-house 1-486 (486) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-486/486
Sequence Identity: 25% (123 aa)

VVLNRKLGEGAFG---TVYGGEALLDD----------------------NKWAAVAVKTLKLG--ASVEEKLD-----------FLSEAEVMKRFN----
..| .|||||.||   .|| ||.  ..                      ..   ||||.||.|  .| ||..|           ||.|||.|| ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIVNLLGVCTRG------------EPMYAVMEFMLYGD----LKTFLLGRRH---------------------------------------------
 |.|||.|.||||.|            ||.. |||.| .||    |...|  .|.                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------LVGEGVYERNQHV------------MCPDQLTSMVSDIASGLSYLASI------NYVHRDLACRNCLVDASYT-----------VKIGDFGMT-
      .... . .. ..             ... ||  |  .||.|..||.|       |.||||||.|||||. ...           .||.|||.. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RALYDSDYYRLGK------------------------RSKLPVRWMAPESLTEGI---------FTTMSDVWSLGVVIYEVVTFG-SFPYQEL
       |..|..|.|.  .                        . |||.||||||.|....         ||| |||||.||...|..|.|   .| ..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN---------AEVLDYIRN--------------RNSLRPPEGCSP-------------ALGAL-MMQCWAIQPQHRPTAKDVNDIL
||         .||..|.|.              |. . .|..|..             .. .. |.|||. .|..||| ... . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase ILGFR.AA UTK 675-943 36 3.7e-103 349.02 In-house 1-296 (296) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-296/296
Sequence Identity: 36% (109 aa)

VVLNRKLGEGAFGTVYGGEALLDD--NKWAAVAVKTLKLGASVEEKLD----FLSEAE---VMKRFN-HKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTF
| | |.||.||||.|. ...  ..   . ..||||... .|. . . .    |. ||    .||.|. | |...|.||||..||.. |.|.|  ||| ..
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LLGRRHLVGEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDAS-------YTVKIGDFG---MTRALY---------DSDYYRL
|   |. ..      ..|    .|...|..|||.|..||.| ..||||||.|||||...       ...||.|||   |.|...         .|.||. 
LRRHRPTPP-----ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA

GKRSKLPVRWMAPESLTEG-IFTTMSDVWSLGVVIYEVVTFGSFPYQELSNAEVLDYIRNR--NSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDVNDI
  . ..|.||||||.||..  ||| |||||.||| .|..|.|. || ..||..|.  ..|.    ...|..|. ..  ||..||.  || ||...|. . 
QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQ

L
.
M
Kinase ILGFR.AA Trk 675-943 43 2e-99 336.59 In-house 1-275 (275) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-275/275
Sequence Identity: 43% (120 aa)

VVLNRKLGEGAFGTVYGGE--ALLDDNKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGRRHLV
.|| . ||||||| |. .|   |. ..    |||||||  ||.. . ||  |||..    |..|| . |||| ..|.  | |.|  |||...|  | |  
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLK-DASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYL--RQHGP

GEGVYERNQH-----VMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYD-SDYYRLGKRSKLPVRWMAPESLTEGIF
   .| ..|       .  ||.   ...||||. |.||  .||||.| ||||| .   |||||||| | .|. .||||.| .  ||.||| |||     |
DAMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKF

TTMSDVWSLGVVIYEVVTFGSFPYQELSNAEVLDYIRNRNS-LRPPEGCSPALGALMMQCWAIQPQHRPTAKDVNDIL
|. |||||.|||. |. |.|  |.  ||| || ..| .    |  |..| . . ..|. ||  .||.| ..||. ||.
TYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase ILGFR.AA TK-Unique 675-943 35 2.8e-90 306.24 In-house 1-294 (294) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-294/294
Sequence Identity: 35% (104 aa)

VVLNRKLGEGAFGTVYGGEALLDD---NKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRFN-HKNIVNLLGVCTRG-EPMYAVMEFMLYGDLKTFLLGRR
.......||||||.|. ||.  ..   .|   ||||.|| .|. ..| |||.|...||    |.|||..||.||.  ||.. .||.. .|.| ..|  .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

HLVGEG------------VYERNQHV-MCPDQLTSMVSDIASGLSYLAS--INYVHRDLACRNCLVDASYTVKIGDFGMTRALYD-SDYYRLGKRSKLPV
    ..            . ....     | .| .   .||.|..||||   . |||||. ||.|.   ...||.||||.| .|.  .| . ......|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMAPESLT--EGIF-TTMSDVWSLGVVIYEVVTFGSFPYQELSNAEVLDYIRNRNSLRPPEGC-SPALGALMMQCWAIQPQHRPTAKDVNDIL
||||||||   .|.. || |||||.||...|..|.|..|| ......... ||.   .  ||.| |...  || .||   |..||.  .. ..|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase ILGFR.AA CTKB 675-945 41 3.8e-83 282.54 In-house 1-269 (269) Show / Hide 
Range on Protein: 675-945
Range on HMM: 1-269/269
Sequence Identity: 41% (114 aa)

VVLNRKLGEGAFGTVYGGEA--LLDDNKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRFN-HKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGRRHL
.||  ||||| || || |||  .. |     ||.| |.  .| |   ||. |  .|.     . || |||.|||  |   |.| |  ||||| |   |  
IVLKQKLGEGHFGVVYAGEAKKIMPDQAVTPVAIKMLQ-DSSSEATNDFMKEVKIMQTIDGDQKIVRLLGICTRETPFLMVLELMAKGDLKTLLRNSRPK

VGEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYDSDYYRLGKRSKLPVRWMAPESLTEGIFTTMSD
            . |  |  |  |.| |. |.||   |||||| |||||   . | |||||. |  | . || .     ||.|||.|||.  |..|| ||
TSKPS------ALSPRRLALMAADVADGMAYIASKRIVHRDLAARNCLVHQNWRVCIGDFGISRDVYMREYYKMQASNPLPIRWMSPESINDGVYTTQSD

VWSLGVVIYEVVTFGSFPYQE-LSNAEVLDYIRNR-NSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDVNDILCQ
||| |.||.|..||.  || | ..| ||   |      .  |..|. .. .||||||   |  |.  |.    .  
VWSYGIVIWEIMTFAKMPYPEYETNMEVVERICDEDYRMWQPKECPDEFYDLMMQCWDEEPDDRISFKELHEKTLL
Kinase ILGFR.AA Src 675-943 37 4.3e-81 275.24 In-house 1-255 (255) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-255/255
Sequence Identity: 37% (103 aa)

VVLNRKLGEGAFGTVYGGEALLDDNKWAA---VAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGRRHL
. | ||||.| || |. |       .|     ||||||| |    .  .|| ||..|| . |...|.|. ||...|| | | |.|  | | ..|      
IKLCRKLGQGQFGEVWMG-------YWNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----

VGEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALY-DSDYYRLGKRSKLPVRWMAPESLTEGIFTTMS
      ..  . .   || .|   .|.| .|| | ||.||||| || ||. .  .|..|||  | .  | | |   . .|.|..|.||| ...| ||. |
------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKS

DVWSLGVVIYEVVTFGSFPYQELSNAEVLDYIRNRNSLRPPEGCSPALGA-LMMQCWAIQPQHRPTAKDVNDIL
|||| |. ..|.||.|  ||   .|.|||. . .   .  |..| . |   .|.|||  .|. ||| .  .. |
DVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase ILGFR.AA Eph 675-943 39 5.4e-81 271.81 In-house 1-264 (264) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-264/264
Sequence Identity: 39% (109 aa)

VVLNRKLGEGAFGTVYGGEALLD-DNKWA---AVAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGRRH
. . . .|.| || |. |   |    .     .||.|||| |..  ...|||||| .|  |.| ||. | || |...|.  | |.|  | | .||  |.|
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFL--RQH

LVGEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYDSD----YYRLGKRSKLPVRWMAPESLTEGIF
   .|        . . ||. |   ||||  ||.. |||||||| || ||..    |. |||..| | | .     |     .| |.|| ||| .. ..|
---DG-------QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKF

TTMSDVWSLGVVIYEVVTFGSFPYQELSNAEVLDYIRNRNSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDVNDIL
|. ||||| |.|. ||...|  || ..|| .|.  |     | || .| .||  ||..||. ...|||. ...  ||
TSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase ILGFR.AA Sev 792-943 45 1.3e-54 180.33 In-house 119-277 (277) Show / Hide 
Range on Protein: 792-943
Range on HMM: 119-277/277
Sequence Identity: 45% (74 aa)

MVSDIASGLSYLASINYVHRDLACRNCLV-----DA--SYTVKIGDFGMTRALYDSDYYRLGKRSK--LPVRWMAPESLTEGIFTTMSDVWSLGVVIYEV
|. ||. | .||  . .||||||||||||      .    .|||||||  |  | .||||  |.    |||||||||||  |.||| ||||. |. . |.
MCIDISKGCEYLEDMHFVHRDLACRNCLVSVKDYTTHRRRVVKIGDFGLARDIYKNDYYR--KEGEGLLPVRWMAPESLMDGYFTTQSDVWAFGILCWEI

VTFGSFPYQELSNAEVLDYIRNRNSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDVNDIL
 | |  ||   || ||| ...    | .|. |   |  .| |||.  |  ||. . . . |
MTLGHQPYPAHSNFEVLNHVQAGGRLQQPRMCPDDLWMMMRQCWRQDPWQRPSFHMCQNML
Kinase ILGFR.AA Ror 796-939 48 4.9e-54 185.84 In-house 128-271 (308) Show / Hide 
Range on Protein: 796-939
Range on HMM: 128-271/308
Sequence Identity: 48% (70 aa)

IASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYDSDYYRLGKRSKLPVRWMAPESLTEGIFTTMSDVWSLGVVIYEVVTFGSFPYQELSN
||.|  ||.|  .|||||| |||||    .||| |||  |  | |||||.  .| .|.|||.||.   | |.. ||.|| |||  |.  .|  ||   ||
IAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEIWSYGMQPYYGYSN

AEVLDYIRNRNSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDV
 || . ||||  |  |..| ..  .||  ||  .|  ||. ||.
QEVIEMIRNRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDI
Kinase ILGFR.AA S_TKc 675-948 25 1e-41 145.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 675-948
Range on HMM: 1-231/231
Sequence Identity: 25% (71 aa)

VVLNRKLGEGAFGTVYGGEALLDDNKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLY--GDLKTFLLGRRHLV
  . ||.|.||||.|| .           ||.| .|         ....| ...|. .|.|||.|..|.   . .| |||..    |||....  |..  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR--

GEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYDSDYYRLGKRSKLPVRWMAPESLTEGIFTT-MSD
     ....... . .  ...  |...| |. | . .||||   | |.|   ..||.|||. | |         .       .|||| |    ...  .|
-----HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCD

VWSLGVVIYEVVTFGSFPYQELSNAEVLDYIRNRNSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDVND----ILCQRPH
.||.|...|| .. |  |..    ..... |.           || .  ....|.   |..|||| ..      | |    
WWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ILGFR.AA Pkinase 675-943 21 2.1e-34 122.71 Pfam 1-293 (293) Show / Hide 
Range on Protein: 675-943
Range on HMM: 1-293/293
Sequence Identity: 21% (69 aa)

VVLNRKLGEGAFGTVYGGEALLDDNKWAAVAVKTLKLGASVEEKL--DFL-SEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYG----DLKTFLLG
 .. ||.|.|.||.|| .    .      ||||..|.    ..|.  ... ||...|||.||.||| |.......  .| |||..  |    ||.... .
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

RRHLVGEGVYERNQHVM--CPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTV----KIGDFGMTRALYDSDYYRLGKRSKLPV---RWMAP
           ... ..   .... ...  |..|| |. | . .||||   |.|.|  ...    ||.|||  . ..    |  .   . ..   ..|||
-----------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAP

ESLT-EGIFTTMSDVWSLGVVIYEVVTFGSFPYQEL----SNAEVLDYIRNRNSLRPPEGCS-----------------------PALGALMMQCWAIQP
| .      .. .|.||.|...||... | .|...     . .. .  |... . .... ..                       ...  ..  |..  |
EVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

QHRPTAKDVNDI--L
. ||||...     .
KKRPTAEQILQHPWF
Kinase ILGFR.AA Sev 675-765 46 8.2e-29 92.99 In-house 1-94 (277) Show / Hide 
Range on Protein: 675-765
Range on HMM: 1-94/277
Sequence Identity: 46% (44 aa)

VVLNRKLGEGAFGTVYGGEALLDD---NKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFL
  | | || |||| || | |   |        ||.|||. |.  .||  || || .| .|.| ||| ..|||  .|| | .|| |  ||| ..|
LKLRRFLGSGAFGEVYEGQAKDIDGVGEEEQRVAIKTLRKGSTDQEKQEFLKEAHLMSKFKHPNIVCQMGVCLDNEPQYIIMEHMEGGDLLCYL
Kinase ILGFR.AA Ror 675-768 41 4.6e-24 86.28 In-house 1-96 (308) Show / Hide 
Range on Protein: 675-768
Range on HMM: 1-96/308
Sequence Identity: 41% (40 aa)

VVLNRKLGEGAFGTVYGGEALLDD--NKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGR
|    .|||..|| || |. ..     .  |||.||.|  ||. .. ||  |...| ...| ||| ||||||  .|. .. |.|  |||  ||  |
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFLIMR