Gene Myo3 (Sea Urchin)
Sequence
Protein domains of Myo3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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MYSc | Myo3.AA | MYSc | 16-634 | 36 | 1.5e-250 | 839.51 | SMART | 1-771 (771) | Show / Hide |
Range on Protein: 16-634 Range on HMM: 1-771/771 Sequence Identity: 36% (287 aa) PVPGRV-VVSNNASMKIL-------------CASDGKTYTGSILVAVNPYKLFDDIYNIENVRRYE------GQLIGHLPPHLFAIGSGAYLRMTQTKQN .| |. .. . | ||.|....|||||| . ||. . ...| |. .. .|||.||| || | . |.| MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKEN QCIVISGESGAGKTESTKLIMQYLAAVNKASTNLITEQILEANPLLEAFGNAKTTRNDNSSRFGKYIEL-FFNNGLISGARTTEYLVEKSRVVRQTSGER |||.|||||||||||.||.|||||||| ... . .|||..||.|||||||||.||.||||||||.|. | ..| |.|| . || ||||||.|. ||| QCIIISGESGAGKTENTKKIMQYLAAVSG-QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNKGER NYHIFYQMLAGMSIGEKAKYGLSQ----PERYFYLNQGG-----------SSRLETRNDADDFIR----TVSAMEVLNFDPNKQETAFSILAAILHIGNL |||||||..|| | .| ...|.. || |.|||||| .......||..| . |..||.|..|. || |.|.|||||.||. NYHIFYQLCAGASEEQKQEFHLKPFSHNPEDYHYLNQGGHYWNNKRHQSQCFTVDGIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAILHLGNI SLQNSKTQDRPDMLE----VTNEGALSGAARLLHIDPKQLEGAILYRVTETIGE---RILTPRTLEQAEDARDGIAKSLYTSLFAWLVRSINGITNQSAK . ... | . . | .| .|. |..|| .||..|| ....|...| .| .| .|...|||..||| .|| .| || |.|. || . EFEQGRNQ-YDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSM----H MTSIAILDIFGFEVFGTNGFEQLCINYANEHLQFYFNKHIFQLEQLEYAKEKIEWQTISFV--DNQPVLDLLAKR---PTGILHILDDESNF---PKGTE ..| .|||.|||.| |.|||.||||.|| || .||.|.| ||| || .|.||| | |. ||||..||. |. | ||. .||.|..| |||| NYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEECMFHAQPKGTD KAFVEKC-----HYHHSSNSSYGRP-----------KQPRLEFCIKHYAGRVIYQLDNVIGKNRDMLKPEVMEMFKNSRNRVLSDMFKL--LQTVEQRRS . |.||. | ||.... . | ...| .| ||||||.| |. . . ||.| | ..... ...|.|... ..|. ||..... QTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYEDQTSQTPQE MMGASGPSG--------------MRKMRPSTVATRFNESLLELINNMNKCHPFFVRCIKPNEEKAPMLFDTPIVLSQLRYSGMLETVRIRRNGFPIRMTF . . | .. | | |..||...| .| ||....|.|||...||||||||| | || . || |||..|.||..|||| ||| |... KSS-QGKNKSRRKKRMMQMKKTCMQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPWDFDDDLVLHQLRCCGVLENIRIRRAGFPYRWPY ---------LSF----------------------------------------------------------------MNR |.. ..| QEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTKVFFRNPGQLFHLEEMRER |
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Myosin_head | Myo3.AA | Myosin_head | 39-634 | 37 | 7.50000000001e-245 | 824.5 | Pfam | 31-713 (765) | Show / Hide |
Range on Protein: 39-634 Range on HMM: 31-713/765 Sequence Identity: 37% (260 aa) TYTGSILVAVNPYKLFDDIYNIENVRRYEGQLIGHLPPHLFAIGSGAYLRMTQTKQNQCIVISGESGAGKTESTKLIMQYLAAVNKAST--N--LITEQI || | ....||||| . || . . |.|. . .|||.||| || .| . ..||||.|.|||||||||.||..|||.|.| . | ...|| TYSGHFCISVNPYKQLP-IYTQDMIQEYRGKHRYEMPPHIFAIADEAYRHMRHDRENQCIIICGESGAGKTENTKYVMQYFASVSGSNPGVNMGRVEQQI LEANPLLEAFGNAKTTRNDNSSRFGKYIELFFN-NGLI----SGARTTEYLVEKSRVVRQTSGERNYHIFYQMLAGMSIGE-KAKYGLS--QPERYFYLN |..||.||||||||||||.||||||||.|. |. | | .|.. . || ||||||.||.||||.|||||.||| | | |....|. |..|.||| LQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQTPGERNFHIFYQLLAGASQQEEKKELHLTSADPKDYHYLN QGG---SSRL-ETRNDADDFIRTVSAMEVLNFDPNKQETAFSILAAILHIGNLS-LQNSKTQDRPDMLEVTNEGA-LSGAARLLHIDPKQLEGAILYRVT |.| .. . . .||. | |..|| ...| |.. |.|.|||||.||. . . ... .| .. . .. .. |. .||. .| ...||. QSGTNPCYTVDDGIDDAEEFQHTRNAMDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQNEEQA---VVDDTEEICEIICELMGVDPEEFEKWLCYRRI ETI----GERILTPRTLEQAEDARDGIAKSLYTSLFAWLVRSINGITNQSA-------------------------------KMTSIAILDIFGFEVF-G .| |.. .| . ||| .||| || .| .| |.|. || . .. . . | .|||.|||.| KTGGGKRREWVTKPQNCEQAMYARDALAKAIYSRMFDWIVNRINQAICHKTQNTDDSDGQAAQWDDTVSITVVDVPDPAFDKRNYFIGVLDIYGFEIFCE TNGFEQLCINYANEHLQFYFNKHIFQLEQLEYAKEKIEWQTISF-VDNQPVLDLLAK-RPTGILHILDDESNFPKGTEKAFVEKCHYHH-SSNS--SY-G |.|||.||||.|| || .|| |.|.||| || .|.|.| | . ||||. ||. | .| ||| .||.|..|||.|.. |..|.. .| | .. . KNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFDNQPCCDLIEKKKPMGILSLLDEECWFPKATDQTFLQKLYQTHSSKHPRLHFAQ RP-KQP------RLEFCIKHYAGRVIYQLDNVIGKNRDMLKPEVMEMFKNSRN-RVLSDMFKLLQT------------------VEQRRSMMGASGPSGM .| ... . .|.||||||.|.|. .. . ||.| | ....| .. |.. . ... |. ... . | . | . . KPGRFYKRHRQGNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQELFPDWEWAEWAHMQIDFEADFHEEEFKRRYNRNGCQKGKQG RKMRP-STVATRFNESLLELINNMNKC---HPFFVRCIKPNEEKAPMLFDTPIVLSQLRYSGMLE-TVRIRRNGFPIRMTFLSFMNR .|... ||. | |.. .|......| || .||||||||.|.| || . ||.|||..|.|| ..||.| ||| |.|. |..| KKKWFMQTVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQR |