Gene Spk382 (Sea Urchin)

Spk382

Species: Sea Urchin
Alias: SPU_018352, Spk382
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: urch
Subfamily: urch-unclassified

Sequence

Name Sequence Type Origin Length Description Download
Spk382.AA Protein None 816 None Fasta, JSON
Spk382.kin_dom Protein Kinase Domain None 215 None Fasta, JSON

Protein domain

Protein domains of Spk382.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk382.AA urch-unclassified 557-767 49 8.20000000001e-152 510.65 In-house 1-215 (215) Show / Hide 
Range on Protein: 557-767
Range on HMM: 1-215/215
Sequence Identity: 49% (107 aa)

LGKGTYGKVYLGRHGDDLRPVAIK-QPVLHSDYRRDMLQQEKLLMNERATKESMVQQLLSGSPYFPKMLGMVTIGDDLCTVMDFIGNKKTGRTYPLYRAL
.||||.|||...||.....||..| ....|.||...|..|.||||.||..||.||..|....||||...|||...|..|.||.|.|.|.|...|||....
IGKGTFGKVFMMRHQREAVPVKVKMIHEHHNDYDYEMRMQNKLLMHERIMKEAMVHRLFADHPYFPRCYGMVKHEDCPCIVMEFLGDKQTYTVYPLCQWI

TRRFKSNPKLGLINMLQVCEDIIKGIMELHREGYLHNDLKSNNILLEKRSK--RWHAIIIDLGLASPMAY-AKQRRFSDKRRAEYRSGKIYTYMAPEVVL
..|.||||.|........|.||..|....|....||||||||||||.....  ||||.|||.|..|.|.. .|||.|||....||..||||..||||.||
HERHKSNPALSKHHWINICMDICHGMHAMHEMDLLHNDLKSNNILLQWCDHDQRWHAYIIDFGMISTMTMPHKQRNFSDHEMREYMMGKIYHHMAPEIVL

YGKRNSVASDIYSFG
||...||.|||||.|
YGQPTSVYSDIYSLG
Kinase Spk382.AA urch 557-767 49 1.5e-134 453.29 In-house 1-217 (217) Show / Hide 
Range on Protein: 557-767
Range on HMM: 1-217/217
Sequence Identity: 49% (107 aa)

LGKGTYGKVYLGRHGDDLRPVAIKQPVLHSDYR--RDMLQQEKLLMNERATKESMVQQLLSGSPYFPKMLGMVTIGDDLCTVMDFIGNKKTGRTYPLYRA
.|.||||.|.|.||... .|||||.|.....|.  ..| ..|.....||.|||.||.||.||.|||||..|.|.|.||||.||.|||.||||..|||...
IGRGTYGRVHLYRHRQTKQPVAIKMPCWPQNYTDMNEMEMEEWKANHERFTKEAMVHQLMSGHPYFPKFYGCVDIDDDLCLVMEFIGDKKTGKSYPLHWC

LT--RRFKSNPKLGLINMLQVCEDIIKGIMELHREGYLHNDLKSNNILLEKRSK-RWHAIIIDLGLASPMAY-AKQRRFSDKRRAEYRSGKIYTYMAPEV
..  |....||.|   |.|...|||..|.|..|..|.||||||..|.|||||.. ||||.|||.|....|.. .|...|.|....||..|..|...|||.
IHKSRMCMPNPHLSKWNWLNIAEDIVHGMMAMHDHGFLHNDLKEDNVLLEKRGHGRWHAVIIDFGWVCTMTMPFKMMHFPDEEMREYMHGHGYCHIAPEC

VLYGKRNSVASDIYSFG
||.|...|.|||.||.|
VLDGQPCSIASDVYSVG
Kinase Spk382.AA urchC 552-770 42 1.4e-76 247.49 In-house 2-223 (223) Show / Hide 
Range on Protein: 552-770
Range on HMM: 2-223/223
Sequence Identity: 42% (94 aa)

SNMPVLGKGTYGKVYLGRHGDDLRPVAIKQPVLHSDYRRDMLQQEKLLMNERATKESMVQQLLSGSPYFPKMLGMVTIGDDLCTVMDFIGNKKTGRTYPL
  .   ||| ||.| |||      ||||| |             |.   | | .||..| |..|..||||.|.| |.|. ..| |  ||| |..|..|.|
TILEMIGKGSYGEVMLGRLNGEKDPVAIKRPYVPQHFTPEKEESEWKQNNGRCEKEARVGQMMSTCPYFPRMYGTVMIDENMCIVTEFIGDKQQGKVYML

YRALTRRFKSNPKLGLI--NMLQVCEDIIKGIMELHREGYLHNDLKSNNILLEKRSKRWHAIIIDLGLASPMAYA-KQRRFSDKRRAEYRSGKIYTYMAP
. |.  |  ..| . .   ||. . ||||.|.. .|  | |||| |  |.||| |  |||..|||.|. | |||   || |.|      . .. . . ||
HDAMCPRKGCDPIPYVQKWNMVAIAEDIIRGVHFMHDFGLLHNDIKDDNVLLEHRKERWHGCIIDMGMVSTMAYPPHQRGFNDVMPDHQK-LYGFIHIAP

EVVL-YGKRNSVASDIYSFGVIL
||.   |   |||||||| ||||
EVLDIDGCQVSVASDIYSVGVIL
Kinase Spk382.AA urchB 551-719 44 7.2e-55 188.6 In-house 1-163 (212) Show / Hide 
Range on Protein: 551-719
Range on HMM: 1-163/212
Sequence Identity: 44% (76 aa)

LSNMPVLGKGTYGKVYLGRHGDDLRPVAIKQPVLHSDYRR--DMLQQEKLLMNERATKESMVQQLLSGSPYFPKMLGMVTIGDDLCTVMDFIGNKKTGRT
   .   | |||| | . ||     | |||||    .|     |    .     |.||| |..||.|.|||||| .|   |. |||    |.|.||||  
INDLQEIGRGTYGRVVIARHRQTKVPLAIKQPCWSDNYQSPNEMVDELHDATRTRVTKEAMIHQLMSDSPYFPKFWGTLDIDNDLCQAQEFVGCKKTGIG

YPLYRALTRRFKSNPKLGLINMLQVCEDIIKGIMELHREGYLHNDLKSNNILLEKRSKRWHAIIIDLGLAS
|||.          | | . | ... |||.||.||.|  | ||||||  |.||||| .|.||.||| |..|
YPLHEP--------PPLSMCNVVDIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGHRYHAVIIDFGMVS
Kinase Spk382.AA urchA 557-764 32 7.6e-50 159.0 In-house 1-208 (208) Show / Hide 
Range on Protein: 557-764
Range on HMM: 1-208/208
Sequence Identity: 32% (69 aa)

LGKGTYGKVYLGRHGDDLRPVAIKQPVLHSDYRRDMLQQEKLLMNERATKESMVQQLLSGSPYFPKMLGMVTIGDDLCTV-MDFIGNKKTGRTYPLYRAL
|| |.|| |.| ||     |||.|   |  .|  .| .  ... |     |  ..|.|...|.||...|   |  |     |.|.|   ||. | .   |
LGRGVYGTVHLYRHRQTDHPVALKVIELPKEY-KKMRRKIECFQN-----EMQIHQVLGCEPWFPTFYGCCEICEDKVGMAMEFCGDEMTGESYTITWCL

TRR-FKSNPKLGLINMLQVCEDIIKGIMELHREGYLHNDLKSNNILLEK-RSKRWHAIIIDLGLASPMAYAK---QRRFSDKRRAEYRSGKIYTYMAPEV
 .   . .|.|    ...|  || .|   .|  | | ||||  |.|. |  . || | |||.|.|.|..        .|. .   .||... . . ||| 
DKAMEMRQPALTRDQWMNVMLDIAEGLKVMHEKGFLCNDLKEDNCLVRKTEFGRWRAKIIDFGWACPCQMPFPACRMHFDQRQKQFYRYCHRCCHIAPEC

VLYGKRNSVASDIY
.| ..  | .||.|
ALDAQPCSTSSDVY
Kinase Spk382.AA TKL 557-770 17 2.9e-19 66.04 In-house 1-279 (364) Show / Hide 
Range on Protein: 557-770
Range on HMM: 1-279/364
Sequence Identity: 17% (53 aa)

LGKGTYGKVYLGRHGD--------DLRPVAIKQ-PVLHSDYRRDMLQQ-------------EKLLMNERATKESMVQQLLS-GSPYFPKMLGMVTIGDD-
.|.|..|.|| |..          . ..||.|. .. ..| . ...|              .. .. .| ..|  . ....   |   ...| .. ... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LCTVMDFI--GNKKTGRTYPLYRALTRRFKSNPKLGLINMLQVCEDIIKGIMELHREG--------YLHNDLKSNNILLEKRSK----
            || ||...  |.        |.  |.          .  ... . || .|.  || ..         .| ||||.|||. .  .    
CVCMHPVGPWGQLCIVMEYCPGGS--------LLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSN

-------RWHAIIIDLGLASPMAYAKQRRFS-----------DKRRAEYRSGKIYTYMAPEVVLYGKRNSVAS---------------DIYSFGVIL
        |.. | |.||.  |   ..   .           . | . .. .  . .|||||      .. ..               |.||||..|
YMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL
Kinase Spk382.AA Ciliate-E2 677-770 25 1.6e-15 49.78 In-house 169-286 (365) Show / Hide 
Range on Protein: 677-770
Range on HMM: 169-286/365
Sequence Identity: 25% (33 aa)

IIKGIMELHREG-YLHNDLKSNNILLEKRSKRWHAIIIDLGLASPMAYAKQRRFSDKRRA-EYRSGK------------------------IYTYMAPEV
||... .|| ..  .| |.| .|||.          |||.||.       |.|.  |... .|   |                         . |||||.
IILALEYLHSKNNIIHRDIKPENILF--------IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEI

VLY--------GKRNSVASDIYSFGVIL
. .        .|. . ..||.|.||||
LNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase Spk382.AA S_TKc 551-811 22 3.3e-15 46.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 551-811
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

LSNMPVLGKGTYGKVYLGRHGDDLRPVAIKQPVLHSDYRRDMLQQEKLLMNERATKESMVQQLLSGSPYFPKMLGMVTIGDDLCTVMDFIGNKKTGRTYP
   . ..|||..||||..|| .. | ||||.                    |.. .|  . .   . |.  |....    |.|. ||.....     .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGD----LGD

LYRALTRRFKSNPK--LGLINMLQVCEDIIKGIMELHREGYLHNDLKSNNILLEKRSKRWHAIIIDLGLASPMAYAKQRRFSDKRRAEYRSGKIYTYMAP
|.. . .| .  ..  .       ..  |....  .|. | .| |||  |||| .     |  |.| |||  .               .       ||||
LFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------------TTFCGTPWYMAP

EVVLYGKRNSV-ASDIYSFGVIL-------------ESIARKIKISEVAE-LAEDCTEQDPLKRPHSMEEIL-----LKMEAI
||.      .  ..|..|.|.||             . . .||. |. |  . . | . || |||   |         ... .
EVL----GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk382.AA Pkinase 551-770 20 2.9e-13 47.96 Pfam 1-202 (293) Show / Hide 
Range on Protein: 551-770
Range on HMM: 1-202/293
Sequence Identity: 20% (47 aa)

LSNMPVLGKGTYGKVYLGRHGDDLRPVAIKQPVLHSDYRRDMLQQEKLLMNERATKESMVQQLLSGSPYFPKMLGMVTIGDDLCTVMDFIGNKKTGRTYP
.    ..|.|..|.||...| .. . ||.|.  .. . . ...|.  .|       |  . . | ..|.  ....... .|... ||.. ..  .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL------SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLY--VMD

LYRALTRRFKSNPKL--GLINMLQVCEDIIKGIMELHREGYLHNDLKSNNILLEKRSKRWHA----IIIDLGLASPMAYAKQRRFSDKRRAEYRSGKI-Y
|.. ...  ... ..         ..  |..|.  .|..| .| |||. |||. ..    |      |.| |||  .           .   . .    .
LFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNG---HIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTP

TYMAPEVVLYGKRNSVASDIYSFGVIL
 ||||||.. |.  . ..|..|.|.||
WYMAPEVIRGGQYYGPKVDMWSCGCIL
Kinase Spk382.AA Ciliate-E2-Unclassified 677-770 27 8e-13 40.84 In-house 152-260 (352) Show / Hide 
Range on Protein: 677-770
Range on HMM: 152-260/352
Sequence Identity: 27% (31 aa)

IIKGIMELHREG-YLHNDLKSNNILLEKRSKRWHAIIIDLGLAS--------------PMAYAKQRRFSDKR-RAEYRSGKIYTYMAPEVVLYGKRNS--
|..|.  ||...  .| |.| .|||. .  |. .  |||.|...               |.. || .....    .| . .   | ||||    . .   
ILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q---YTAPEVLQGQNYDHSK

-VASDIYSFGVIL
  ..||.|.||||
AYKCDIWSLGVIL
Kinase Spk382.AA STE 673-767 23 8.7e-11 34.44 In-house 156-255 (359) Show / Hide 
Range on Protein: 673-767
Range on HMM: 156-255/359
Sequence Identity: 23% (27 aa)

VCEDIIKG-IMELHREGYLHNDLKSNNILLEKRSKRWHAIIIDLGLASPMA--YAKQRRFS----------DKRRAEYRSGKIYTYMAPEVVLYGKRN--
.| .|.||    ||. .. | |.|. ||||        . ..| |... ..  .|.. . |          ...|          .|||||.. ....  
ICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP---WMAPEVIQQNGQGRD

---SVASDIYSFG
   .. .||.|.|
KGYDTKCDIWSLG
Kinase Spk382.AA TyrKc 551-808 18 4.6e-09 -76.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 551-808
Range on HMM: 1-280/280
Sequence Identity: 18% (61 aa)

LSNMPVLGKGTYGKVYLGRHGDDLRPVAIKQPVLHSDYRRDMLQQEKLLMNE--RATKESMVQQLLSGSPYFPKMLGMVTIG-------DDLCTVMDFIG
..   .|| | .|.||.|.     ..||.|    ..  |.|...  .....   .              |   ...| .| .       . |. || .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHH-------------PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP

N-------KKTGRTYPLYRALTRRFKSNPKLGLINMLQVCEDIIKGIMELHREGYLHNDLKSNNILLEKRSKRWHAIIIDLGLASPMAYA-KQRRFSDKR
.       .|....                | .  .|. | .| .|   ||. .. | ||   |.|. ..    .. | | ||.       .|      .
HGDLKDYLRKHRPK----------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQG----ES

RAEYR-----SGK---IYTYMAPEVVLYGKRNSVASDIYSFGVIL----------------------------ESIARKIKISE------------VAEL
   ||     .||    .  ||||.  |||  . .||..|||| .                            ..  |  .  .            . ..
KDYYRKKEHKGGKTMLPIRWMAPECINYGK-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQI

AEDCTEQDPLKRPHSMEEILLKM
 ..| . || .|| ...||  ..
MKQCWHEDPEDRP-TFSEIHECF
Kinase Spk382.AA LISK 556-594 33 4.5e-08 22.1 In-house 1-45 (296) Show / Hide 
Range on Protein: 556-594
Range on HMM: 1-45/296
Sequence Identity: 33% (15 aa)

VLGKGTYGKVYLGRHGDDLRPVAIKQPVL------HSDYRRDMLQ
..||| .|||| |.|  . ...|||.           .|.. ||.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLR
Kinase Spk382.AA LISK 684-718 36 3.1e-07 19.36 In-house 117-152 (296) Show / Hide 
Range on Protein: 684-718
Range on HMM: 117-152/296
Sequence Identity: 36% (13 aa)

LHREGYLHNDLKSNNILLEKR-SKRWHAIIIDLGLA
||  . .| ||||.|.|. .. . .| ....|.|.|
LHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFA
Kinase Spk382.AA urchB 745-767 52 4.1e-07 21.9 In-house 190-212 (212) Show / Hide 
Range on Protein: 745-767
Range on HMM: 190-212/212
Sequence Identity: 52% (12 aa)

YMAPEVVLYGKRNSVASDIYSFG
| ||||.| |   |..||..| |
YIAPEVILHGQSTSISSDVFSVG
Kinase Spk382.AA STE 551-581 21 8.2e-05 13.06 In-house 1-46 (359) Show / Hide 
Range on Protein: 551-581
Range on HMM: 1-46/359
Sequence Identity: 21% (10 aa)

LSNMPVLGKGTYGKVYLGRHGD---------------DLRPVAIKQ
. .. ..|||..|.||.... .                 . .||||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQ
Kinase Spk382.AA TKL 781-808 42 0.00036 10.93 In-house 338-364 (364) Show / Hide 
Range on Protein: 781-808
Range on HMM: 338-364/364
Sequence Identity: 42% (12 aa)

EVAELAEDCTEQDPLKRPHSMEEILLKM
....|..|| ..|| ||| |..||| ..
SMKKLMQDCWDHDPEKRP-SFQEILKRL
Kinase Spk382.AA Pkinase_Tyr 746-768 56 0.000494 14.28 Pfam 181-202 (270) Show / Hide 
Range on Protein: 746-768
Range on HMM: 181-202/270
Sequence Identity: 56% (13 aa)

MAPEVVLYGKRNSVASDIYSFGV
||||.  |||  ...||..||||
MAPECINYGK-FTTKSDVWSFGV
Kinase Spk382.AA Pkinase_Tyr 551-580 32 0.002511 11.89 Pfam 1-34 (270) Show / Hide 
Range on Protein: 551-580
Range on HMM: 1-34/270
Sequence Identity: 32% (11 aa)

LSNMPVLGKGTYGKVYLGRHG----DDLRPVAIK
.. . .||.| .|.||.|.      ..  |||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase Spk382.AA LISK 746-770 44 0.002902 6.23 In-house 206-229 (296) Show / Hide 
Range on Protein: 746-770
Range on HMM: 206-229/296
Sequence Identity: 44% (11 aa)

MAPEVVLYGKRNSVASDIYSFGVIL
||||..| |.  . ..|..|||..|
MAPEMLL-GQSYDESCDVFSFGIVL
Kinase Spk382.AA Ciliate-E2-Unclassified 556-581 34 0.040588 3.17 In-house 6-31 (352) Show / Hide 
Range on Protein: 556-581
Range on HMM: 6-31/352
Sequence Identity: 34% (9 aa)

VLGKGTYGKVYLGRHGDDLRPVAIKQ
..|.| .||||. .| ..    |.|.
QIGQGGFGKVYKCQHKKQKQYYAMKY
Kinase Spk382.AA Ciliate-E2 556-570 33 0.055593 2.57 In-house 6-20 (365) Show / Hide 
Range on Protein: 556-570
Range on HMM: 6-20/365
Sequence Identity: 33% (5 aa)

VLGKGTYGKVYLGRH
..|.|..|.||....
KIGQGNFGSVYKCKV