Gene Spk208 (Sea Urchin)

Spk208

Species: Sea Urchin
Alias: SPU_012192, Spk208
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: urch
Subfamily: urchA

Sequence

Name Sequence Type Origin Length Description Download
Spk208.AA Protein None 537 None Fasta, JSON
Spk208.kin_dom Protein Kinase Domain None 163 None Fasta, JSON

Protein domain

Protein domains of Spk208.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk208.AA urchA 292-490 54 7.2e-147 476.72 In-house 1-208 (208) Show / Hide 
Range on Protein: 292-490
Range on HMM: 1-208/208
Sequence Identity: 54% (114 aa)

LGSGANGTVHLYRHRATDHPIALKTFELPDDIKAMTRKVKAIQSEAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMTGES----WTLSR--GM
||.|..|||||||||.||||.|||..|||...|.|.||....|.|..|..|||.|..||||.||.||...|.|.||.|.||.|||||    |.|..  .|
LGRGVYGTVHLYRHRQTDHPVALKVIELPKEYKKMRRKIECFQNEMQIHQVLGCEPWFPTFYGCCEICEDKVGMAMEFCGDEMTGESYTITWCLDKAMEM

RKLALSQQDWLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDAPY---FYRFSDENKEKYRRREVYVHIAPECALDDVL
|..||....|....||||..|...||||||.|||||||||.|||..|||.|.|.|||.||||..|.   ...|. . |. || .  . |||||||||   
RQPALTRDQWMNVMLDIAEGLKVMHEKGFLCNDLKEDNCLVRKTEFGRWRAKIIDFGWACPCQMPFPACRMHFDQRQKQFYRYCHRCCHIAPECALDAQP

TSVSSDVF
 | ||||.
CSTSSDVY
Kinase Spk208.AA urch 292-493 38 2.5e-111 376.13 In-house 1-217 (217) Show / Hide 
Range on Protein: 292-493
Range on HMM: 1-217/217
Sequence Identity: 38% (84 aa)

LGSGANGTVHLYRHRATDHPIALKTFELPDDIKAMTR--------KVKAIQSEAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMTGES----W
.|.|..|.|||||||.|..|.|.|....|.....|..        .......||...........||.|.||..|. ....|.|.|.||..||.|    |
IGRGTYGRVHLYRHRQTKQPVAIKMPCWPQNYTDMNEMEMEEWKANHERFTKEAMVHQLMSGHPYFPKFYGCVDID-DDLCLVMEFIGDKKTGKSYPLHW

TLS---RGMRKLALSQQDWLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDAPY-FYRFSDENKEKYRRREVYVHIAPE
...   ..|....||...||. |.||.... ..|..|||.|||||||.||.|...|||.|||.|||..|....|. ...|.|| .. |.....|.|||||
CIHKSRMCMPNPHLSKWNWLNIAEDIVHGMMAMHDHGFLHNDLKEDNVLLEKRGHGRWHAVIIDFGWVCTMTMPFKMMHFPDEEMREYMHGHGYCHIAPE

CALDDVLTSVSSDVFQLG
|.||   .|..|||. .|
CVLDGQPCSIASDVYSVG
Kinase Spk208.AA urch-unclassified 292-493 28 1.1e-43 151.43 In-house 1-215 (215) Show / Hide 
Range on Protein: 292-493
Range on HMM: 1-215/215
Sequence Identity: 28% (61 aa)

LGSGANGTVHLYRHRATDHPIALK--TFELPDDIKAMTRK---VK--AIQSEAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMTGESWTLSRG
.| |. | | ..|| ..  | . |       |..  | ..   .    |  || .  ...    ||  .|  ..  .  ...|.| ||  |.   .|.. 
IGKGTFGKVFMMRHQREAVPVKVKMIHEHHNDYDYEMRMQNKLLMHERIMKEAMVHRLFADHPYFPRCYGMVKHE-DCPCIVMEFLGDKQTYTVYPLCQW

MRKLA-----LSQQDWLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPT-GRWQAVIVDFGLACPCDA-PYFYRFSDENKEKYRRREVYVHIAPECA
          || . |.  ..|| . .   ||.. | |||| .| ||.. .   || | | |||.. . .    . .|||. .. |.   .| |.|||  
IHERHKSNPALSKHHWINICMDICHGMHAMHEMDLLHNDLKSNNILLQWCDHDQRWHAYIIDFGMISTMTMPHKQRNFSDHEMREYMMGKIYHHMAPEIV

LDDVLTSVSSDVFQLG
|.   ||| ||.. ||
LYGQPTSVYSDIYSLG
Kinase Spk208.AA urchC 336-496 28 8.1e-16 47.5 In-house 57-223 (223) Show / Hide 
Range on Protein: 336-496
Range on HMM: 57-223/223
Sequence Identity: 28% (49 aa)

EAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMTGESWTLSRGMR-------KLALSQQDWLALALDIAKSLGRIHEKGFLMNDLKEDNCLL--
|| .. .. .   || ..| . |  . . .   |.||  .| .. |   |         . ..    .| | || .    .|  | | || | || ||  
EARVGQMMSTCPYFPRMYGTVMID-ENMCIVTEFIGDKQQGKVYMLHDAMCPRKGCDPIPYVQKWNMVAIAEDIIRGVHFMHDFGLLHNDIKDDNVLLEH

RKTPTGRWQAVIVDFGLACPCDAP-YFYRFSDENKEKYRRREVYVHIAPECALD--DVLTSVSSDVFQLGRLL
||    || ..|.| |.      | ..  |.|   .  ..   ..|||||  ||     .||.||..  | .|
RKE---RWHGCIIDMGMVSTMAYPPHQRGFNDVMPDH-QKLYGFIHIAPEV-LDIDGCQVSVASDIYSVGVIL
Kinase Spk208.AA TESK 387-450 39 7.5e-13 36.46 In-house 88-155 (292) Show / Hide 
Range on Protein: 387-450
Range on HMM: 88-155/292
Sequence Identity: 39% (27 aa)

KLALSQQDWLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA----CPCDAP
.|.|| .  . ||.|||. .  .|.||    ||   ||| |. .   ..||. |||||    |  | |
ELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGDFGLARVLGCMPDPP
Kinase Spk208.AA urchB 349-450 39 1.2e-10 34.73 In-house 72-168 (212) Show / Hide 
Range on Protein: 349-450
Range on HMM: 72-168/212
Sequence Identity: 39% (40 aa)

FPTFLGCLEISPGKIGLAMDFVGDTMTGESWTLSRGMRKLALSQQDWLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCD
|| |.| | |      .|  |||   ||  . |        ||    .  | || | .  .|  | | |||| || || |    |. |||.|||..    
FPKFWGTLDID-NDLCQAQEFVGCKKTGIGYPL---HEPPPLSMCNVVDIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGH-RYHAVIIDFGMVSTIT

AP
||
AP
S_TKc Spk208.AA S_TKc 283-537 13 1.8e-08 -52.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 283-537
Range on HMM: 1-231/231
Sequence Identity: 13% (40 aa)

FHKGGSDVFLGSGANGTVHLYRHRATDHPIALKTFELPDDIKAMTRKVKAIQSEAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMT--GESWT
....     .|.|| |.|.. ||. |..  |.|               . |..|  ||    . .   ..... .   ... . |...    .  |.  .
YEILR---KIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYC---DGDLGDLFD

LSRGMRK----LALSQQDWLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDAPYFYRFSDENKEKYRRREVYVH----I
. . ...      ..  .   ..  |.. |  .|..|..  ||| .| || .      .  | |||||.                       ..     .
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------------------TTFCGTPWYM

APECALDDVLTSV-SSDV-------FQLGRLLTLMGGATTNADLTAIGNICRQSSKLC-------------RPSIDEVVA-----ELERMM
|||        .  ..|.       . .    ..        .. .. .... |. ..             ||.. |. .      .   .
APEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk208.AA LISK 398-444 38 2.1e-08 23.2 In-house 106-152 (296) Show / Hide 
Range on Protein: 398-444
Range on HMM: 106-152/296
Sequence Identity: 38% (18 aa)

LALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
.|||||...   |... .  |||  |||.|. . ..|.... |||.|
IALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFA
Kinase Spk208.AA IKK 289-334 23 5.4e-07 20.22 In-house 4-49 (297) Show / Hide 
Range on Protein: 289-334
Range on HMM: 4-49/297
Sequence Identity: 23% (11 aa)

DVFLGSGANGTVHLYRHRATDHPIALKTFELPDDIKAMTRKVKAIQ
.  ||.|| | | ..||..|.  .| |...  .  ..... .. ..
CDRLGQGAFGNVYHWRHKKTGRKVAVKHCNHMSWMRCRWVWCREFE
Kinase Spk208.AA TKL 292-444 16 2e-06 19.1 In-house 1-201 (364) Show / Hide 
Range on Protein: 292-444
Range on HMM: 1-201/364
Sequence Identity: 16% (36 aa)

LGSGANGTVHLYRHRATD--------HPIALKTFELPDDIK--------------------AMTRKVKAIQSEAFILDVLG-REDCFPTFLG-CLEIS--
.|||. |.|.  ..| ..         ..| |.|   .| .                    ... .    . |  |.  .  | .    |.| |....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------PGKIGLAMDFV-----GDTMTGESWTLSRGMRKLALSQQDWLALALDIAKSLGRIHE--------KGFLMNDLKEDNCLLRKTPT------
         .|.... |...      ....                 .  . .|||||. .   |         .. .  ||| .|.|. .  |      
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYM

----GRWQAVIVDFGLA
      | . | ||||.
YNPNADWCCKICDFGLS
Kinase Spk208.AA Ciliate-C7 399-444 47 4e-06 16.05 In-house 108-149 (164) Show / Hide 
Range on Protein: 399-444
Range on HMM: 108-149/164
Sequence Identity: 47% (22 aa)

ALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
| |||  |  ||.|....|||| || |          ||. |||||
AKDIAQGLYYIHSKNCVVNDLKMDNILIDY----NGNAVVCDFGLA
Kinase Spk208.AA urchB 472-493 59 4e-06 18.43 In-house 191-212 (212) Show / Hide 
Range on Protein: 472-493
Range on HMM: 191-212/212
Sequence Identity: 59% (13 aa)

IAPECALDDVLTSVSSDVFQLG
||||  |..  ||.|||||  |
IAPEVILHGQSTSISSDVFSVG
Kinase Spk208.AA LISK 291-315 36 0.212995 0.07 In-house 1-25 (296) Show / Hide 
Range on Protein: 291-315
Range on HMM: 1-25/296
Sequence Identity: 36% (9 aa)

FLGSGANGTVHLYRHRATDHPIALK
 .|.|. | |   .||.|  ..|.|
EIGKGFFGKVYKGTHRQTGQVMAIK