Sgk071b

Species: Sea Urchin
Alias: Spk204, SPU_023136, Sgk071b
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: SgK071

Sequence

Name Sequence Type Origin Length Description Download
Sgk071b.AA Protein None 285 None Fasta, JSON
Sgk071b.kin_dom Protein Kinase Domain None 191 None Fasta, JSON

Protein domain

Protein domains of Sgk071b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Sgk071b.AA SgK071 1-201 52 2.6e-143 482.39 In-house 1-216 (283) Show / Hide
Range on Protein: 1-201
Range on HMM: 1-216/283
Sequence Identity: 52% (113 aa)

MISTFAEGPQGVTFLVKHRTNGKTYILKKIECNDDPEANRALREVMRLTKLSHRHLAVPRDAFVHWDSAEAAMYLCIVSDYFVTGDLDSFLKEKSRKGKS
.      | |||.|.|.|...||....|..||.||..||.||.|||.|.||.|.|..|..|.|||||..|||||||||.||...||.|.|.|||..|.|.
LLYMLNPGAQGVNFVVEHMETGKKFVIKQVECMDDHHANKALEEVMPLQKLQHPHICVYHDMFVHWDKEEAAMYLCIVMDYYKMGDFDRFMKEKRKKKKI

MCESDMQRWMGQLLHAITYLHDSGIAHTDLKPSNVYLTPQMDLRIGDFGIRTVIEDLHRFRCRTRT---------------AVWSLYWSPPEVFEGPHGS
|||..||||.||.||||.|||...|.|.||||||.|||.||.....||||.|...|.|...||.||               .|||.||..|||.|.|...
MCEEWMQRWCGQMLHAIEYLHHRNIIHRDLKPSNIYLTDQMHCKLQDFGIQTIMTDKHKWNCRARTENTALSGPSTLILSADVWSMYWMAPEVLEFPFSQ

KTDIWSLGCMLFEMTA
|.|||||||....||.
KSDIWSLGCIILDMTT

Kinase Sgk071b.AA S_TKc 1-269 23 1.2e-35 125.66 SMART 3-231 (231) Show / Hide
Range on Protein: 1-269
Range on HMM: 3-231/231
Sequence Identity: 23% (66 aa)

MISTFAEGPQGVTFLVKHRTNGKTYILKKIECNDDPEANRALREVMRLTKLSHRHLAVPRDAFVHWDSAEAAMYLCIVSDYFVT--GDLDSFLKEKSRKG
.. .  .|  |. ....|.  |. . .|.|        ....||.  | |  | ..    |.|..        .|..| .|  .  ||| ...|.. |.|
ILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--KSMCESDMQRWMGQLLHAITYLHDSGIAHTDLKPSNVYLTPQMDLRIGDFGIRTVIEDLHRFRCRTRTAVWSLYWSPPEVFEGPHGS-KTDIWSLGCM
  . . | . ...| |.. |. |.|. || | ||||.|. |.    . |.|||. ...          .| . .... .|||.  ..|  | |.||.||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCI

LFEMTA---MVHQSVLKSRAVLLQLRVGDRVEFLETLKQIGLGYEKSCHICDCVMQMLLADHDVRPSARDVLK-------MHYP
|.|| .     .                   .  ...|.||     |   .| ....|  | . ||.| ..|.       . . 
LYEMLCGYPPFP-------------------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase Sgk071b.AA NEK-Unclassified 80-269 29 3.5e-35 113.72 In-house 73-258 (258) Show / Hide
Range on Protein: 80-269
Range on HMM: 73-258/258
Sequence Identity: 29% (57 aa)

DYFVTGDLDSFLKEKSRKGKSMCESDMQRWMGQLLHAITYLHDSGIAHTDLKPSNVYLTPQMDLRIGDFGIRTVIEDLHRFRCRTRTAVWSLYWSPPEVF
||   |.||  .. .  |   . |  . .| .|.  |. | |   | | ||||.|..||    . .||||| .....    | . || | .  |  ||| 
DYCDGGNLDRRIQKHRKKNEPFDEGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHT---RDKARTCVGTMCWMSPEVC

EG-PHGSKTDIWSLGCMLFEMTAMV----HQSVLKSRAVLLQLRVGDR-VEFLETLKQIGLGYEKSCHICDCVMQMLLADHDVRPSARDVLKMHYP
.  |   . |.|||||...|| .       .. .    |.     .|  .|  | |  ..  |  |    . .  ||  . . |||| ... . | 
QDQPYNNRSDVWSLGCIIYEMCTCEPFFDTHNMGE---VYMKIKQDDNRLE--EALEPVSKTY--STDLQQVIRFMLRRNFQQRPSATEIVEQDYI

Kinase Sgk071b.AA Pkinase 11-199 23 9.4e-28 99.21 Pfam 13-205 (293) Show / Hide
Range on Protein: 11-199
Range on HMM: 13-205/293
Sequence Identity: 23% (49 aa)

GVTFLVKHRTNGKTYILKKIECNDDPEANR--ALR--EVMRLTKLSHRHLAVPRDAFVHWDSAEAAMYLCIVSDYFVTG----DLDSFLKEKSRKGKSM-
|. .. .|. .||.. .|.|.  .. .  .  ..|  |.  . .|.| .    .|.|          ....| .|   |    || ....   ...... 
GCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDYIST--WRHGCFY

-CESDMQRWMGQLLHAITYLHDSGIAHTDLKPSNVYLTPQMDL----RIGDFGIRTVIEDLHRFRCRTRTAVWSLYWSPPEV--FEGPHGSKTDIWSLGC
  | . ...| |.| .. |.|. || | ||||.|. .  ....    .|.|||.  ...  .     . | . .... .|||  .  ..|.| |.||.||
FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGC

MLFEM
.|.||
ILYEM

Kinase Sgk071b.AA CAMK 4-199 16 1.6e-25 78.57 In-house 1-327 (425) Show / Hide
Range on Protein: 4-199
Range on HMM: 1-327/425
Sequence Identity: 16% (54 aa)

TFAEGPQGVTFLVKHR-TNGKT-----------YILKKIECN----------------------------DDPEANRALREVMRLTKLS-------HRHL
|  .|  |. .|..|. |.||.           .  | |. .                            ..    . .||.  . ||.       |...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AVPRDAFV----------------HWDSAEAAMYLCI-VSDYFVTG----DLDSFLKEKSRKG-----------KSMCESDMQRWMGQLLHAITYLHDSG
    ...                 .. . .  ||.   ...|   |    || ....|....|           . ..|.. .|.. |.. |. |.|. .
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHTDLKPSNVYLTPQM-----------------DLRIGDFGIRTVIEDLHRFRCR--------------------TRTAVWSLYWSP-PEVFEG-----
|.| |||| |. |.  .                 .. | |||  ..... .  ..                      .| . ...  . |||..|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

----------PHGSKTDIWSLGCMLFEM
          ..| |.|.||.|..|. |
MQNATDEEKPYYGPKCDMWSCGVILYIM

Kinase Sgk071b.AA NEK4 1-204 30 2.8e-24 84.2 In-house 3-200 (257) Show / Hide
Range on Protein: 1-204
Range on HMM: 3-200/257
Sequence Identity: 30% (64 aa)

MISTFAEGPQGVTFLVKHRTNGKTYILKKIECN--DDPEANRALREVMRLTKLSHRHLAVPRDAFVHWDSAEAAMYLCIVSDYFVTGDLDSFLKEKSRKG
 .     |  |  .||.||  .| |..||..    .  |   |..|.  | .| |       . .      |   .|.||  .   |||   ||..  |.
HMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESW----EIENGQFLYIVMGFCEGGDLYRKLKQQ--KN

KSMCESDMQRWMGQLLHAITYLHDSGIAHTDLKPSNVYLTPQMDLRIGDFGIRTVIEDLHRFRCRTRTAVWSLYWSPPEVFEG-PHGSKTDIWSLGCMLF
. . |.    |  |   |  |.|.  | | |||  |..|| .  ..||||||  |...   .    .| .   |.  ||.|   |   | ||||||| ..
QFLEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDM---AKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVY

EMTAMVH
||  . |
EMITLKH

Kinase Sgk071b.AA Ciliate-E2-Unclassified 74-199 24 5.7e-21 69.48 In-house 95-263 (352) Show / Hide
Range on Protein: 74-199
Range on HMM: 95-263/352
Sequence Identity: 24% (41 aa)

YLCIVSDYFVTGDLDSFLKEKS-------------RKGKSMCESDMQ-----RWMGQLLHAITYLHDSG-IAHTDLKPSNVYLTPQM---DLRIGDFGIR
...|| .|.  |||  ..|...             ...|   |  ..     ... |.| .. ||| .. | | |.||.|. .. ..    ..| |||| 
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS

T-----VIEDLHRF--------RCRTRTAVWSLYWS----PPEVFEG-PHG----SKTDIWSLGCMLFEM
      . .| ..         .... | .....      .|||..|  ..     | ||||||. |.||
KKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM

Kinase Sgk071b.AA TKL 5-199 16 6.6e-21 72.01 In-house 1-282 (364) Show / Hide
Range on Protein: 5-199
Range on HMM: 1-282/364
Sequence Identity: 16% (49 aa)

FAEGPQGVTFLVKHRTNG--------KTYILKKIECNDDP---------------------------EANRALREVMRLTKLSHRHLAVPRDAFVHWDSA
  .|  |. .  |.| .|        |.   ||.  ..|                            .  .  .|.| . .|.| ..      |.  . .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIV----QFMGYCCC

EA---AMY--------LCIVSDYFVTGD-LDSFLKEKSRKGKSMCESDMQRWMGQLLHAITYLHDSG--------IAHTDLKPSNVYLTPQMD-------
.    ...        |||| .|   |. |. ..            . . ||. .   .. ||| ..        |.| |||..|. .   .        
PPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMY

-------LRIGDFGIRTVIEDLH----------------RFRCRTRTAVWSLYWSPPEVFE-----------------GPHGSKTDIWSLGCMLFEM
       . |.|||. ....                   . |..| | . ...| .|||..                 ..   |.|..| | .|.|.
NPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI

Kinase Sgk071b.AA Ciliate-E2 74-199 21 7.8e-19 61.26 In-house 108-289 (365) Show / Hide
Range on Protein: 74-199
Range on HMM: 108-289/365
Sequence Identity: 21% (40 aa)

YLCIVSDYFVTGDLDSFLKEK---------SRKGKSMCESDMQRWMGQLLH---------------AITYLHDSG-IAHTDLKPSNVYLTPQMDLRIGDF
.. .| .|.  ||| ...|..         . . |.. |  ... | |.|                |. |||  . | | |.||.|. .     . | ||
NIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDF

GI-RTVIEDLHRFR---------------------------CRTRTAVWSLYWSPPEVFEGP----------HGSKTDIWSLGCMLFEM
|. . . .|  . .                             ..| .....  .||...|           .. | ||||||..|.||
GLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

Kinase Sgk071b.AA CMGC 11-149 17 7.9e-19 57.65 In-house 13-249 (513) Show / Hide
Range on Protein: 11-149
Range on HMM: 13-249/513
Sequence Identity: 17% (42 aa)

GVTFLVKH--------------RTNGKTYILKKIECN-DDPEAN----------RALREVMRLTKLS-----------------HRHLAVPRDAFVHWDS
|| .  ..              . ... . .|||  . .. .|           |||||.. | .|.                 | ..   .| |.| .|
GVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNS

AEAAM-----------YLCIVSDYFVTGDLDSFLKEKSR-----KGKSMCESD------------MQRWM------GQLLHAIT--YLHDSG--IAHTDL
.               .|..| .|  . ||  ..|....     ... . |               .  |       |.| ..   |.|  .  | |.||
DGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDL

KPSNVYLTPQ--------------------MDLRIGDFG
||.|. ....                    . |.|.|||
KPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFG

Kinase Sgk071b.AA NEK1 1-150 28 7.3e-14 44.62 In-house 3-167 (276) Show / Hide
Range on Protein: 1-150
Range on HMM: 3-167/276
Sequence Identity: 28% (48 aa)

MISTFAEGPQGVTFLVKHRTNGKTYILKKIECND--DPEANRALREVMRLTKLSHRHLAVPRDAFVHWDSAEAAMYLCIVSDYFVTGDLDSFLKEKSRKG
 |..  ||  | ..||||.  |..| .| |  .   . |  ....||  |.|. |      ...|.    ..    | || .|   |||    ... |||
YIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFE----ENGCGILYIVMEYCDGGDLMQKINRQKRKG

KSMCESDMQRWMGQLLHAITYLHDSGIAHTDLKPSNVYLT-PQMD----------------LRIGDFGI
|.  |     |  |.  |  . ||  | | |.|..|. ||  . .                ...|||||
KLFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGI

Kinase Sgk071b.AA NEK 74-150 36 4.5e-13 42.74 In-house 80-169 (286) Show / Hide
Range on Protein: 74-150
Range on HMM: 80-169/286
Sequence Identity: 36% (33 aa)

YLCIVSDYFV-TGDLDSF---LKEKSRKGKSMCESDMQRWMGQLLHAITYLHDS-----GIAHTDLKPSNVYLTPQMD----LRIGDFGI
.|||| .|    |||. .   .|..  ||| . |.   .|. |.. |. |.||       | | |.||.|. || .      ..||||||
CLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGI

Kinase Sgk071b.AA TyrKc 25-267 17 1e-08 -81.61 SMART 1-280 (280) Show / Hide
Range on Protein: 25-267
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

YILKKI---------------------ECNDDPEANRALREVMRLTKL--SHRHLAVPRDAFVHWDSAE-----AAMYLCIVSDYFVTGDLDSFLKEKSR
  |.|.                      ...|      .||   ..||  .| ..     ...   . .      .  |.||  |   |||...|... .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIV----RLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KGKSMCESDMQRWMGQLLHAITYLHDSGIAHTDLKPSNVYLTPQMDLRIGDFGIRTVIEDL-------HRFRCRT---RTAVWSLYWSPPEVF-EGPHGS
|    | .|.  .. |      |||. .. | ||   |. .. .   .|.|||    |.|           | ..   . ... . | .||.. .|   .
K---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KTDIWSLGCMLFEMTAMVHQSV-------LKSRAVLLQLRVGDRVEFLETLKQIGLGYE-----KSCHICDCVMQMLLAD-HDVRPSARDVLKMH
|.|.|| | ...|.     |         .. . |. ... |.| .  .         .      .  . . .|..  .   . ||. ... .  
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY------PMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF

Kinase Sgk071b.AA NEK 172-201 51 2e-06 19.31 In-house 189-219 (286) Show / Hide
Range on Protein: 172-201
Range on HMM: 189-219/286
Sequence Identity: 51% (16 aa)

YWSPPEVF-EGPHGSKTDIWSLGCMLFEMTA
|.  |||. . | ..| ||||||| |.|| .
YYMSPEVCQNKPYNNKSDIWSLGCVLYEMCT

Kinase Sgk071b.AA NEK1 186-204 57 1.1e-05 15.84 In-house 201-219 (276) Show / Hide
Range on Protein: 186-204
Range on HMM: 201-219/276
Sequence Identity: 57% (11 aa)

KTDIWSLGCMLFEMTAMVH
|.||||||| | | ..  |
KSDIWSLGCVLYELCTLKH

Kinase Sgk071b.AA CMGC 175-199 27 1.9e-05 12.88 In-house 293-328 (513) Show / Hide
Range on Protein: 175-199
Range on HMM: 293-328/513
Sequence Identity: 27% (10 aa)

PPEVFEGP-----------HGSKTDIWSLGCMLFEM
.||.  |             ... |.||.||...||
APEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEM

Kinase Sgk071b.AA NEK 7-55 28 0.000579 10.3 In-house 9-65 (286) Show / Hide
Range on Protein: 7-55
Range on HMM: 9-65/286
Sequence Identity: 28% (16 aa)

EGPQGVTFLVKHRTNGKT-----YILKKIECNDD--PEANRAL-REVMRLTKLSHRH
.| .|. ..|... .||      |..|||  .     |   |.  ||  | .| | .
QGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPN

Kinase Sgk071b.AA NEK 248-269 40 0.017811 5.0 In-house 265-286 (286) Show / Hide
Range on Protein: 248-269
Range on HMM: 265-286/286
Sequence Identity: 40% (9 aa)

QMLLADHDVRPSARDVLKMHYP
|||  |.. |||....|.| . 
QMLQKDPEQRPSCNQILEMPFI

Kinase Sgk071b.AA NEK4 246-269 41 0.03562 3.83 In-house 234-257 (257) Show / Hide
Range on Protein: 246-269
Range on HMM: 234-257/257
Sequence Identity: 41% (10 aa)

VMQMLLADHDVRPSARDVLKMHYP
| |||    . ||| .|...| | 
VYQMLEKQPTKRPSIFDIFQMPYI

Kinase Sgk071b.AA SgK071 249-268 30 0.12794 1.42 In-house 264-283 (283) Show / Hide
Range on Protein: 249-268
Range on HMM: 264-283/283
Sequence Identity: 30% (6 aa)

MLLADHDVRPSARDVLKMHY
||  .   |.|..||... .
MLHINPQDRISIKDVMHITF