Gene MPSK1 (Sea Urchin)

MPSK1

Species: Sea Urchin
Alias: SPU_023601, Spk166, MPSK1
External Links: Sea Urchin Project Link ,
Annotation:

Classification

Group: Other
Family: NAK
Subfamily: MPSK

Sequence

Name Sequence Type Origin Length Description Download
MPSK1.AA Protein None 302 None Fasta, JSON
MPSK1.kin_dom Protein Kinase Domain None 277 None Fasta, JSON

Protein domain

Protein domains of MPSK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MPSK1.AA MPSK 17-291 61 3.4e-230 771.01 In-house 1-281 (281) Show / Hide 
Range on Protein: 17-291
Range on HMM: 1-281/281
Sequence Identity: 61% (172 aa)

FYVMKRLGEGGFSVVDQVED-EVGEKFALKRIQCHGAEDDRQAKKEAEYHCQFKHKNLIGLEEWGSVKGKE-----GVTEILLVLPLFKRGTLQDELDKM
.|.|.||||||||.||.||. ..|...||||||||...|..||..|||.||||.|.|.|.|..||..||.|     ...||.||||.||.|||.|.|..|
YYFMQRLGEGGFSYVDLVENLHDGHFYALKRIQCHEQQDQNQAQREAEMHCQFDHPNIIRLVDWGCLKGREDIVINTKHEIWLVLPYFKHGTLWDHLQRM

KADGRCMAEERIWRIFKGVCEGIKALHTAKPKPLAHRDMKPGNVMLAEDDTPVIMDFGSMGEARIEVKGRSEACALQDLAAEKCSMLFRAPELFHVDSHC
|..|.||.|..||.||.|||||.||.|.|.|||.|||||||.|..|..|..|||||.|||.||.|.|||...||||||.|||.|||..||||||||.|||
KDKGDCMTEDQIWWIFLGVCEGLKAIHEAMPKPYAHRDMKPTNICLGDDFQPVIMDLGSMNEACIQVKGQRQACALQDWAAERCSMVYRAPELFHVQSHC

IVEEKVDIWSLGCVLFNMAYLHSPFEPIYARGDSIHLAVLGRNFKFPENSRYSQGLQDTVSGMLVVEAVERPNIDWVLNKT
...|..|||||||||..|.|.|||...||.||||.||||..|||..||||||||......|.|..|...|||.|.||||.|
VIDERTDIWSLGCVLYAMCYFHSPYDMIYQRGDSVHLAVQNRNFNIPENSRYSQDMHQLISYMMRVDPMERPHIFWVLNQT
Kinase MPSK1.AA NAK 17-291 38 1.2e-150 506.18 In-house 1-299 (299) Show / Hide 
Range on Protein: 17-291
Range on HMM: 1-299/299
Sequence Identity: 38% (114 aa)

FYVMKRLGEGGFSVVDQVED----------EVGEKFALKRIQCH-GAEDDRQAKKEAEYHCQFKHKNLIGLEEWGSVKGKE---GVTEILLVLPLFKRGT
..|.|.|.|||||.|..|.|          . |||.||||..|| ...|....|.|.|......|.| | . .........   |..|..|.......|.
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

LQDELDKMK-ADGRCMAEERIWRIFKGVCEGIKALHTAK-PKPLAHRDMKPGNVMLAE---DDTPVIMDFGSMGEARIEVKGRSEACA---LQDLAAEKC
|.|...|.. ..|.|. |..|..|| .||||..|.|... |||..|||.|..|..| |   |......||||| .|.|....| ||..   .||......
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYT

SMLFRAPELFHVDSHCIVEEKVDIWSLGCVLFNMAYLHSPFEPIYARGDSIHLAVLGRNFK--FPENSRYSQGLQDTVSGMLVVEAVERPNIDWVLNKT
.. .||||.....|.|...||||||.|||.|..|.. ..|||..|.|.||..||.. .|.|  .|.||||||...| ...||.... .||||..|||..
TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase MPSK1.AA NAK-Unclassified 17-293 21 2.7e-59 203.33 In-house 1-405 (405) Show / Hide 
Range on Protein: 17-293
Range on HMM: 1-405/405
Sequence Identity: 21% (88 aa)

FYVMKRLGEGGFSVVDQVE--------D-------EVGEKFALKRIQCHGAEDDRQAKKEAEYHCQFK-HKNLIGLEEWGSVKGKEGV--TEILLVLPLF
  . . |.||||| |  |         |         ... .|||. |   |    .| | .    |. |.| . ..    .. . ..  .|....... 
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC

KRGTLQDELD------KMKADGRCMAEERIWRIFKGVCEGIKALHTAKP-------------------------------------------KPLAHRDM
.||.|||  .      .    .    |  . .|. .||.|| ..|   |                                            ||.||| 
SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI

KPGNVMLA---------------------------------------------------------EDD-TPVIMDFGSMGEARIEVKGRSEACALQDLAA
|..|| .                                                          |..  ....||||  |..| .. | |.  |||   
KIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIENRQEMQYLQDWIN

EKCSMLFRAPELFHVDSHCIVEEKVDIWSLGCVLFNMAYLHSPFEPIYARGDSIH-----LAVLG--RNFKFPENSRYSQGLQDTVSGMLVVEAVERPNI
  .    ||||..   . |.  ||.|||.||| |. |..  .|||    .....|     ...|    ...|| |..|| .|      ||..   .||||
MHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFE----MCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNI

DWVLNKTTE
  |||.  .
YQVLNHICQ
Kinase MPSK1.AA S_TKc 17-289 18 1.3e-32 115.6 SMART 1-220 (231) Show / Hide 
Range on Protein: 17-289
Range on HMM: 1-220/231
Sequence Identity: 18% (52 aa)

FYVMKRLGEGGFSVVDQVEDEV-GEKFALKRIQCHGAEDDRQAKKEAEYHCQFKHKNLIGLEEWGSVKGKEGVTEILLVLPLFKR--GTLQDELDKMKAD
. ... .|.|.|..| .. .   |...|.|.|        .....| . . . .|.|.. | ..         ... .|. .     |.| | ..|..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

GRC--MAEERIWRIFKGVCEGIKALHTAKPKPLAHRDMKPGNVMLAEDDTPVIMDFGSMGEARIEVKGRSEACALQDLAAEKCSMLFRAPELFHVDSHCI
|..  . | ....... .|.... .|  .     ||| || |..| |  .  | |||.  .                      .  ..|||..       
GLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL------G

VEE-KVDIWSLGCVLFNMAYLHSPFEPIYARGDSIHLAVLGRNFKFPENSRYSQGLQDTVSGMLVVEAVERPNIDWVLN
    |.|.||.||.|. |..   ||.         ..... .. .       |. . | ....|...  .|| .  .|.
YGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase MPSK1.AA BIKE 19-284 29 4e-29 101.48 In-house 3-261 (267) Show / Hide 
Range on Protein: 19-284
Range on HMM: 3-261/267
Sequence Identity: 29% (79 aa)

VMKRLGEGGFSVVDQVEDEVGEKFALKRIQCHGAEDDRQAKKEAEYHCQFK-HKNLIGLEEWGSVKGKEGVTEILLVLPLFKRGTLQDELDKMKADGRCM
| . | ||||..|  | |. | |.||||      .|   ...| .   |   |||..|          .|| |...  .  ..  . . . .    |. .
VEEQLAEGGFAMVFLVRDHKGNKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGVWECMILMEYCRH-QVVNMMNQRLQQGQYF

AEERIWRIFKGVCEGIKALHTAKPKPLAHRDMKPGNVMLAEDD--TPVIMDFGSMGEARIEVKGRSEACALQDLAAEKCSMLFRAPELFHVDSHCIVEEK
 |. . .||  ||| .  ||  .  |  |||.|  |..| .      |  ||||      ...  .   . .|       | .||||.    |  ..  |
TEQEVLQIFCDVCEAVSRLHHCQ-TPIIHRDLKVENILLHDHGPPHYVLCDFGSATNKFLNPQKHG-VNYVKDEIEKYTTMCYRAPEMIDLYSGKEITTK

VDIWSLGCVLFNMAYLHSPFEPIYARGDSIHLAVLGRNFKFPENSRYSQGLQDTVSGMLVVEAVERPNI
 ||| ||| |. . .   ||      | |  ||.   ||..|.||.||....  .  || . .  ||.|
ADIWALGCMLYKLCFFCLPF------GES-QLAICDGNFTIPDNSKYSREMHCLIRYMLEPDMEKRPDI
Kinase MPSK1.AA Ciliate-E2 17-289 16 1.1e-17 57.28 In-house 1-361 (365) Show / Hide 
Range on Protein: 17-289
Range on HMM: 1-361/365
Sequence Identity: 16% (63 aa)

FYVMKRLGEGGFSVVDQVED-EVGEKFALKRIQCHG------------AEDDRQAKKEAEYHCQFKHKNLI-GLEEWG-----------------SVKGK
. . | .|.|.|..| .... .|...||.|.|. .              .     .|. .   ... ....  ... .                  .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMY

EGVTE-----ILLVLPLFKRGTLQDELDKM---------KADGRCMAEERIWRIFKGVCE---------------GIKALHTAKPKPLAHRDMKPGNVML
|   |     | ||. ... |.|.| . ..         | |  .. |. | .|.| ...               ... ||  ..    ||| || |...
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF

AEDDTPVIMDFGSMGEARIEVKGRSEACALQDLAAEKC------------------------SMLFRAPELFHVDS------HCIVEEKVDIWSLGCVLF
     . | |||   .. .. . |.. . .. .  .                          .  . ||| .   .      .    .|.||||||..|.
-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

NMAYLHSPFEPIYARGDSIHLAVLGRNFKFP----------------ENSRYSQGLQDTVSG----MLVVEAVERPN-IDWVLN
 | .   ||              .  ...||                ..   ||  .|  .     ||...  .|.. .. .||
EMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase MPSK1.AA Pkinase 17-169 19 9.7e-17 60.27 Pfam 1-158 (293) Show / Hide 
Range on Protein: 17-169
Range on HMM: 1-158/293
Sequence Identity: 19% (33 aa)

FYVMKRLGEGGFSVVDQVEDEVGEK-FALKRIQCHGAED--DRQAKK--EAEYHCQFKHKNLIGLEEWGSVKGKEGVTEILLVLPLFKRG----TLQDEL
. . ...|.|.|..| .  .   .| .|.|.|  .....  |... .  |....  ..|.| . | .|         ..| .|...   |     |    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLF---

DKMK-ADGRCM--AEERIWRIFKGVCEGIKALHTAKPKPLAHRDMKPGNVMLAEDDTP----VIMDFGS
| ..  ...|.   |. . .... ...|.. .|        |||.|| |... .....     | |||.
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase MPSK1.AA SgK071 19-229 26 4.2e-14 45.31 In-house 1-215 (283) Show / Hide 
Range on Protein: 19-229
Range on HMM: 1-215/283
Sequence Identity: 26% (58 aa)

VMKRLGEGGFSVVDQVED-EVGEKFALKRIQCHGAEDDRQAKKEAEYHCQFKHKNLIGLEEWGSVKGKEGVTEIL-LVLPLFKRGTLQDELDKMKADGRC
. ..|. |   |.  ||. | | || .|.. |       .| .|.      .| .. .  .      ||    .| .|   .| |...  . . .  .  
LLYMLNPGAQGVNFVVEHMETGKKFVIKQVECMDDHHANKALEEVMPLQKLQHPHICVYHDMFVHWDKEEAAMYLCIVMDYYKMGDFDRFMKEKRKKKKI

MAEERIWRIFKGVCEGIKALHTAKPKPLAHRDMKPGNVMLAEDDTPVIMDFGS---MGEAR-IEVKGRSEACALQD-----LAAEKCSMLFRAPELFHVD
| || . |.   . . |  ||  .    .||| || |..| ....  . |||.   |  ..   .. | |  ||       |.|  .||   ||| .   
MCEEWMQRWCGQMLHAIEYLHHRN---IIHRDLKPSNIYLTDQMHCKLQDFGIQTIMTDKHKWNCRARTENTALSGPSTLILSADVWSMYWMAPEVLEF-

SHCIVEEKVDIWSLGCVLFNMA
..    .| |||||||... |.
PF---SQKSDIWSLGCIILDMT
Kinase MPSK1.AA CAMKL 17-168 25 1.1e-11 33.38 In-house 1-174 (297) Show / Hide 
Range on Protein: 17-168
Range on HMM: 1-174/297
Sequence Identity: 25% (46 aa)

FYVMKRLGEGGFSVVDQVED-EV-GEKFALKRIQCHGAEDDRQAKK---------------EAEYHCQFK---HKNLIGLEEWGSVKGK--EGVTEILLV
. . | ||.|.|..|   ..    ||| | | |   .. .| ..||               |.. . ...   |.| | | |    . .  |  ..| ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

LPLFKRGT--LQDELDKMKADGRCMAEERIWRIFKGVCEGIKALHTAKPKPLAHRDMKPGNVMLAEDD--TPVIMDFG
. .   |   |.| ..| .  .. | |.   |.|. ...... .|  .    .||| || |..| |..  .  | |||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG---IVHRDIKPENILLDENGNNNIKIIDFG
Kinase MPSK1.AA CAMK 22-168 15 1.2e-11 33.13 In-house 1-241 (425) Show / Hide 
Range on Protein: 22-168
Range on HMM: 1-241/425
Sequence Identity: 15% (39 aa)

RLGEGGFSVVDQVEDE-VG------------EKFALKRIQCHGAE----------------------------DDRQAKKEAEYHCQ-------FKHKNL
 ||.|.|..|  ...   .            .|.| | |    .                             | .. ..| | . .        .|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IGLEEWGSV-----------KGKEG----VTEILLVL---PLFKRGTLQDE-LDKMKADGRC--------------MAEERIWRIFKGVCEGIKALHTAK
| | |.                . .     ... .|.    .   | | |. .|. .. |..              . |.   |.|. .|.... .|  .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

PKPLAHRDMKPGNVMLAEDD-----------------TPVIMDFG
    .||| || |..| ...                 .  | |||
---IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFG
Kinase MPSK1.AA NEK10 119-168 44 4.4e-11 32.55 In-house 118-165 (279) Show / Hide 
Range on Protein: 119-168
Range on HMM: 118-165/279
Sequence Identity: 44% (22 aa)

EERIWRIFKGVCEGIKALHTAKPKPLAHRDMKPGNVMLAEDDTPVIMDFG
|||||..|  .|     ||  | |   |||..| |.|. ..|  .| |||
EERIWHMFIQMCLALRYLH--KEKQIVHRDLTPNNIMMGDKDRVTITDFG
Kinase MPSK1.AA NEK 214-236 60 2.8e-09 29.23 In-house 203-227 (286) Show / Hide 
Range on Protein: 214-236
Range on HMM: 203-227/286
Sequence Identity: 60% (15 aa)

EKVDIWSLGCVLFNMAYLHS--PFE
.|.|||||||||. |. |..  |||
NKSDIWSLGCVLYEMCTLKPKHPFE
Kinase MPSK1.AA CAMK 214-285 18 3.3e-09 25.08 In-house 313-417 (425) Show / Hide 
Range on Protein: 214-285
Range on HMM: 313-417/425
Sequence Identity: 18% (20 aa)

EKVDIWSLGCVLFNMAYLHSPFE-----PIYARG-------DSIHLAVLGRNFKFP-----------------------ENSRYSQGLQDTVSGMLVVEA
.|.|.||.|..|. |   ..||.      |.  .         ..  ..  .. ||                       ..   ||  .| ...||.|. 
PKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-DEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQVDP

VERPNID
 .|..|.
EKRMTIE
Kinase MPSK1.AA Pkinase 215-290 19 6.9e-09 32.5 Pfam 192-290 (293) Show / Hide 
Range on Protein: 215-290
Range on HMM: 192-290/293
Sequence Identity: 19% (19 aa)

KVDIWSLGCVLFNMAYLHSPFE-P----IYARGDSIHLAVLGRNFKFPENSRYS-------------------QGLQDTVSGMLVVEAVERPNIDWVLNK
|||.||.||.|. |.  . ||         .. . ..  ..|. ..|..   .|                   . ..| ....| .   .||... .|. 
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH
Kinase MPSK1.AA NEK10 214-235 50 5e-07 18.96 In-house 199-220 (279) Show / Hide 
Range on Protein: 214-235
Range on HMM: 199-220/279
Sequence Identity: 50% (11 aa)

EKVDIWSLGCVLFNMAYLHSPF
|| |.|. ||.|. |. |  ||
EKADVWAFGCCLYQMCTLQPPF
Kinase MPSK1.AA CAMKL 215-285 25 2e-06 16.7 In-house 216-289 (297) Show / Hide 
Range on Protein: 215-285
Range on HMM: 216-289/297
Sequence Identity: 25% (21 aa)

KVDIWSLGCVLFNMAYLHSPFEPIYARGDSI----------HLAVLGRNFKFPENSRYSQGLQDTVSGMLVVEAVERPNID
||||||.| .|..| . . ||.     .|..          .. . .  ...|  .. |  ..|  ..||.|   .||.|.
KVDIWSCGVILYAMVCGYLPFD-----DDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIH
Kinase MPSK1.AA NEK 17-62 20 1.1e-05 16.42 In-house 1-55 (286) Show / Hide 
Range on Protein: 17-62
Range on HMM: 1-55/286
Sequence Identity: 20% (11 aa)

FYVMKRLGEGGFSVVDQVEDEVGEK------FALKRIQCHGA--EDDRQAK-KEA
. . | .|.| |..|  |..   .|      ...|.|.  .   .. ..|  .|.
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEV
Kinase MPSK1.AA TyrKc 17-291 17 6.6e-05 -143.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-291
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

FYVMKRLGEGGFSVVDQVEDEVGEKFALKRIQCHGAEDDRQAKKEAEYHCQF--KHKNLIGLEEWGSVKGKEGV---TEILLVLPLFKRGTLQDELDKMK
    | |||| | .| . .    .. | | .. .     .   .||.  |..  .|.|.. |    . .|         ...|. . . | |.| | | .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLRKHR

ADGRCMAEERIWRIFKGVCEGIKALHTAKPKPLAHRDMKPGNVMLAEDDTPVIMDFGSMGEARIE-VKGRSEACALQDLAAEKCSM--L-FR--APELFH
 .      .    .   ...|   ||     .. |||    |....|. |  | ||| . .   .  .|  |.    . . .|..   |  |  ||| . 
PK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECI-

VDSHCIVEEKVDIWSLGCVLFNMAYLHSPFEPIY----ARGDSIHLAVLGRNFKFPENS-------RYSQGLQDTVSGMLVVEAVERPNIDWVLNKT
   ...  .| |.|| | ... .  .  .  |         . ..  |  ..   .  .       . .. . .  .     .. .||.   .  . 
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MPSK1.AA NEK 100-164 29 0.000343 11.11 In-house 90-162 (286) Show / Hide 
Range on Protein: 100-164
Range on HMM: 90-162/286
Sequence Identity: 29% (22 aa)

R-GTLQDE---LDKMKADGRCMAEERIWRIFKGVCEGIKALHTAKPKPLA---HRDMKPGNVMLAEDDT--PVI
. |.|..    . | |  |  . || ||..|   | ..| .|  |  |     ||| || |..|  ...  ...
GGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GPQRKILHRDIKPQNIFLTKNNNDYHNV
Kinase MPSK1.AA NEK 260-293 33 0.000929 9.57 In-house 251-286 (286) Show / Hide 
Range on Protein: 260-293
Range on HMM: 251-286/286
Sequence Identity: 33% (12 aa)

SR--YSQGLQDTVSGMLVVEAVERPNIDWVLNKTTE
|.  ||| ||. .| || ..  .||... .|..   
SHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI