Gene CRK7 (Sea Urchin)

CRK7

Species: Sea Urchin
Alias: SPU_028236, Spk127, CRK7, SpCDC2L5
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7

Sequence

Name Sequence Type Origin Length Description Download
CRK7.AA Protein None 1264 None Fasta, JSON
CRK7.kin_dom Protein Kinase Domain None 295 None Fasta, JSON

Protein domain

Protein domains of CRK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CRK7.AA CRK7 498-792 62 1.6e-241 808.66 In-house 1-343 (343) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-343/343
Sequence Identity: 62% (213 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVRTDNE---KEGFPITAVREIKILRQLNHDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
.|.|.|||||||||||||..|.|||.|||||||.|||   ||||||||.|||||||||||.....|.|||||||||..|||.||.||.||||||||||||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LESG-LVNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKTRPYTNKVITLWYRPPELLLGEERY--------
|||. ...||......||||||.|..||||.|||||||||||||.||.|..|.|||||||||....|.|||||.||||||||||||||||||        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------GPAVDVWSCGCILGELFTQRPIFQANQELAQLELISRICGTPTPAVWPDVIRLPLFNTMKPKKMYNRRLR
                              ||..|.||||||||||||..||||.|.|.||||.|..|||.|.|..||.|..||..||||||..||||||
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

EEFS------LLPKDALDLLDGMLTLDPDKRTTAEDALNCGWL
|||.      ..||..|||||.||.|||.||.|||..|...|.
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CRK7.AA CDK 498-792 42 1.9e-172 556.22 In-house 1-284 (284) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-284/284
Sequence Identity: 42% (138 aa)

FEIINQIGEGTYGQVYKARDKDTG-----ELVALKKVRTDN-----EKEGFPITAVREIKILRQLNHDSVIRLHEIVTDKQDALDFKKDK--GAFYLVFE
.|....|||||||.|||||||.||     ..|||||.|..|     |||||||||.|||..|..| |. ...||.....|... .. |||    .|.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YMDHDLMGLLESGLVNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGH-----IKLADFGLARLYH-----ADDKTRPYTNKVITLWYRP
||||||.....          ....|.|||.||.|||.....|||.|..|||.||.|.     .|.|||||||...     . ...|.||..|.|||||.
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRA

PELLLGEERYG--PAVDVWSCGCILGELFT---QRPIFQANQELAQLELISRICGTPTPAVWPDVIRLPLFNTMKPKKMYNRRLREEFSLLPKDALDLLD
||||||...|.  ...|.||.|||..|.||    .|.|. ..|. ||..|.|||||||. .||.|  ||..                         |||.
PELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLN

GMLTLDPDKRTTAEDALNCGWL
.||..||.|| .||.||.. ..
KMLCYDPKKRISAEQALQHPYF
Kinase CRK7.AA CMGC 498-792 27 1.9e-143 474.75 In-house 1-513 (513) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-513/513
Sequence Identity: 27% (139 aa)

FEIINQIGEGTYGQVYKARD--------------KDTGELVALKKVR---TDN------EKEGFPITAVREIKILRQLN----------------HDS-V
.|||..|||||||.|||.||              ..|.|.||.||..    ..      ||.||||.| ||||||..||                |.  .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IRLHEIVTDKQDALDFKKDK-------GAFYLVFEYMDHDLMGLLES--------GLVNFSEEH------------VRSFM------KQLLDGLN--YCH
..|..|...|... . ..||         .||||||||||| .....        . ...|| |            ...||      .|.| ||.  |||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

KRN--FLHRDIKCSNILLNNK--------------------GHIKLADFGLARLYHAD-------------------DKTRPYTNKVITLWYRPPELLLG
...  ..|||.| .|||.|..                    |..|..|||||| ||                     ...||||. | |.|||.||.|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

E---------ERYGPAVDVWSCGCILGELFTQ--------RPIFQANQE-----------LAQLELISRICGTPT---------------PAVWPDVIRL
            |....|.||.|||..|..|         .|.|. . |           . ||..| ...||||               .  ||..| |
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PLFNT-------------MK------------PKKMYNRRLREEFSL-----------------------------------LPKDALDLLDGMLTLDPD
| .|.             ..             .. . . ... |                                     ....|.|||..||..|||
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRTTAEDALNCGWL
|| |||.||.  ..
KRITAEQALQHPYF
Kinase CRK7.AA CDC2 498-792 39 4e-122 377.27 In-house 1-301 (301) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-301/301
Sequence Identity: 39% (124 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVRTDNEKEG--FPITAVREIKILRQLN-HDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
.. |. ||||||| |||..|..|...|||||.|...| ||  .| ||.||| .|  |. |. ...||...                |.||||.|.||  .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-----------NKLYMVFEYLDMDLKKY

LESGLV---NFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKTRPYT--NKVITLWYRPPELLLGEERYGPAV
..  ..   ..... |.|.|.|.|.|...|| |  .|||.| .|||...|| ||.|||||||        |.||    |.|||||.||.|||..||  .|
MDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIP--IRTYTTEHEVVTLWYRAPEILLGCKRYSTPV

DVWSCGCILGEL---FTQRPIFQANQELAQLELISRICGTPTPAVWPDVIRLP-------LFNTMKPKKMYNR--RLREEFSLLPKDALDLLDGMLTLDP
|.|| |||. |.    | .|.|..  |  ||  | || |||.   ||.|  ||        ... ...|.  .    ... | |.....|||. || .||
DMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQ-SCLDPEGIDLLMQMLQYDP

DKRTTAEDALNCGWL
 || .|..||.  ..
QKRISAKEALQHPYF
Kinase CRK7.AA CDK9 498-792 41 6.1e-120 404.76 In-house 1-340 (340) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-340/340
Sequence Identity: 41% (142 aa)

FEIINQIGEGTYG-----------QVYKARDKDTGELVALKKVRTDNEKEGFPITAVREIKILRQLNHDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEY
.| .. || ||.|            |.||| | .. .||.|||  .|||||||||| ||||.| .| |. |. | ||   |  |    ||.  |||||..
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFDF

MDHDLMGLLESGLVNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLAR---LYHADDKTRP-YTNKVITLWYRPPELLLGE
 .||| |||   .| ||  |... |..|. ||.| |.   |||| |  |.|    |  |||||||||   .   | . || ||| |.||||||||||||.
CEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLGD

ERYGPAVDVWSCGCILGELFTQRPIFQANQELAQLELISRICGTPTPAVWPDVIRLPLFNTM------KPKKMYNRRLREEFSLLPK-------------
  |||..|.|  |||. |. |  || | | |  || |||  ||  ||.||| .  ..|.|.|         |   |....    . |             
RNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSKTDPFGK

-----------DALDLLDGMLTLDPDKRTTAEDALNCGWL
           .|..|.| .|..||.|| ....||.  | 
NVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF
Kinase CRK7.AA PITSLRE 498-792 42 6.1e-116 391.49 In-house 1-295 (295) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-295/295
Sequence Identity: 42% (130 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVRTD--NEKEGFPITAVREIK-ILRQLNHDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
|...|.|.||||| ||.|.|| |.| ||||..  .   ||||||||..|||. ||. |.|. .. . |||          ...   |.|.||..||| .|
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIV--------MGSNMDKIYMVMEYVEHDLKSL

LESGL---VNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKTRPYTNKVITLWYRPPELLLGEERYGPAVDV
.|        |..  . ..| ||| |  . |.   .||| |.||.|...||  |..|||||| |      .|||  |.||||| |||||| . | ..||.
MENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSP--IKPYTPCVVTLWYRAPELLLGCKKYSTPVDM

WSCGCILGELFTQRPIFQANQELAQLELISRICGTPTPAVWPDVIRLPLFNTMK--PKKMYNRRLREEFS---LLPKDALDLLDGMLTLDPDKRTTAEDA
|| |||..|. |..|.|| . |. |.. |    ||||   ||..  ||... |.  |.  ||  ||. |    ..   ..||| .|||..| .| ||.||
WSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYN-NLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDA

LNCGWL
|  .| 
LKHPWF
Kinase CRK7.AA CDK7 498-792 39 9.40000000001e-115 307.09 In-house 1-288 (288) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-288/288
Sequence Identity: 39% (118 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVR----TDNEKEGFPITAVREIKILRQLNHDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMG
.|.| .||||... ||||.|. ||. || ||..    ..  | |   ||.||||||. . || || |  |   |             .|||..|| ||  
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKS----------NIQLVFDFMDWDLEV

LLESGLVNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKTRPYTNKVITLWYRPPELLLGEERYGPAVDVWS
  .   . .   |. ..|...| || |||.   ||||.|  | |.|  | .|.||||||| | .  .   || .|.| ||| |||| |   ||..||.||
VIKDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRI--YTHQVVTRWYRAPELLFGARHYGTGVDMWS

CGCILGELFTQRPIFQANQELAQLELISRICGTPTPAVWPDVIRLPLFNTMKPKKMYNR-RLREEFSLLPKDALDLLDGMLTLDPDKRTTAEDALNCGWL
 |||. ||    |..    .. ||. | .. ||||.. ||..  .. ....|.   | |  ||. |.  . |.|||. ||.|..| ||.|. ..|.    
VGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CRK7.AA CDK5 498-792 40 8.3e-106 335.36 In-house 1-287 (287) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-287/287
Sequence Identity: 40% (122 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVRTDNEKEGFPITAVREIKILRQLNHDSVIRLHEIV-TDKQDALDFKKDKGAFYLVFEYMDHDLMGLLE
.| .. ||||||| |||||.|.|.|.||||.|| |.| || | ||.||| .|. | |  ..||| .. ..|              ||||..| ||   ..
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKK-----------LTLVFEFCDQDLKKYMD

SGLVNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKTRPYTNKVITLWYRPPELLLGEERYGPAVDVWSCGC
|  .. . . ..||| ||| || .||... |||| |  | | | .|. ||||||||| .    ..  |.  |.|||||||  |.|   |   .|.|||||
SCNGEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRC--YSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGC

ILGELF-TQRPIFQANQELAQLELISRICGTPTPAVWPDVIRLPLFN---TMKPKKMYNRRLREEFSLLPKDALDLLDGMLTLDPDKRTTAEDALNCGWL
|. |.  . || |  |..  || .| .| |||.   || .  || ..   .  |.   .  . .    | .  .||| .|| ..|..| .|..||.  . 
IFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CRK7.AA Pkinase 498-792 33 2.9e-104 357.48 Pfam 1-293 (293) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-293/293
Sequence Identity: 33% (105 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVRTDNEKEGFPITAVR--EIKILRQLNHDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEYMDH-----D
..|. .||.|..|.|||...|.||..||.|... ..||.....|..|  ||.|.. |||. ..||.....|          |.  |.|.||...     |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----------KDHIYMVMEYCEGGLYVMD

LMGLLE-SGLVNF--SEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHI----KLADFGLARLYHADDKTRPYTNKVITLWYRPPELLLGEE
|. ... .   .|  ||......|.|.| ||.|||.....|||.| .|||..|.|||    |..|||||...    . . .|  . |.||..||...| .
LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQ

RYGPAVDVWSCGCILGELFTQRPIFQAN----QELAQLELISRICGTPTPAVWPDVIRLPLFNTMKPKKMYNRRLREEFSLLPKDALDLLDGMLTLDPDK
 |||.||.||||||| |... ||.|.        . |...| || |.|..  ||  .. ..|.  .. .   . ...   .......|.....|..|| |
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKK

RTTAEDALNCGWL
| |||..|.  |.
RPTAEQILQHPWF
Kinase CRK7.AA S_TKc 498-792 29 2.4e-101 343.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-231/231
Sequence Identity: 29% (92 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVRTDNEKEGFPITAVREIKILRQLNHDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEYMDH---DLMGL
.||...||.|..|.|||.|.|.||..||.|...         ... |||.||.. .|. ...|...  |           . .|.|.||.|.   ||. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----------DHLYMVMEYCDGDLGDLFDY

LESGLVN-----FSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKTRPYTNKVITLWYRPPELLLGEERYGP-A
...   .     |.| |.|..|.|....|.|||.....|||.| .||||..  |||..||||||..         |  . |.||..||.|     ||. .
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCK

VDVWSCGCILGELFTQRPIFQANQELAQLELISRICGTPTPAVWPDVIRLPLFNTMKPKKMYNRRLREEFSLLPKDALDLLDGMLTLDPDKRTTAEDALN
.|.||||||| |... .| |.      |.... ...|                                    ...|.|.....|. ||.|| || .||.
CDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

-------CGWL
         |.
DEWDIKCHPWF
Kinase CRK7.AA CDK10 498-792 42 2.7e-95 322.92 In-house 1-285 (285) Show / Hide 
Range on Protein: 498-792
Range on HMM: 1-285/285
Sequence Identity: 42% (126 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVRTDNEKEGFPITAVREIKILRQLNHDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLES
|| .| .|||||| ||.|||  . |.||||||| | ||.| || ..|||..| |. |. ...|||.|  ..  ||      . .|| .| . ||  ||. 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQH--LD------SIFLVMQYCEQDLASLLDN

GLVNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKTRPYTNKVITLWYRPPELLLGEERYGPAVDVWSCGCI
    |.| .|.  | |.| || | |..  .|||.| ||.|.  || ||.||||||| |      .| | |..||||| ||||||      |.|.|  |||
MPQPFTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVP--VKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCI

LGELFTQRPIFQANQELAQLELISRICGTPTPAVWPDVIRLPLFNTMKPKKMYNRRLREEFSLLPKDALDLLDGMLTLDPDKRTTAEDALNCGWL
||||  ..|..  | |..|...|  . |||  ..||    ||. .    ||     |.. | .| .  . ||. ..  .| || |||..|.  . 
LGELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase CRK7.AA MAPK 498-788 32 6.2e-84 285.15 In-house 1-324 (328) Show / Hide 
Range on Protein: 498-788
Range on HMM: 1-324/328
Sequence Identity: 32% (107 aa)

FEIINQIGEGTYGQVYKARDKD------TGELVALKKVRTDNEKEGFPITAVREIKILRQL-NHDSVIRLHEIVTDKQDALDFKKDK---GAFYLVFEYM
..|. .||.| ||.| .|.||       .|. ||.||.    ... .   . ||||.|| . .|. .|.| .| | ..   |  ...     .|.|.|.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEM-Q-DDQNSLEEFNDIYIVMELM

DHDLMGLLESGLVNFSEEHVRSFMKQLLDG--LNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKTRPY------------TNKVITLWY
..||  ...|.    |..|...|| |.| |  | | |  | .|||.| ||||.|  .  |..||||||  . ... .              |  | | ||
ETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWY

RPPELLLG--EERYGPAVDVWSCGCILGELFT-QRPIFQANQELAQLELISRICGTPTPAVW---P-D------VIRLPLFNTMKPKKMYNRRLREEFSL
| ||..|.    .|  |||.||.|||..|. | ..|.|. .  . |..||  ..|||.. ..   . .      . .|...  ...|  ..    . | .
RAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF-N

LPKDALDLLDGMLTLDPDKRTTAEDALN
   .|.|||. ||..||||| |.|.||.
ANPQAIDLLEKMLVFDPDKRITVEEALQ
Kinase CRK7.AA Pkinase_Tyr 498-703 28 5.8e-25 85.18 Pfam 1-209 (270) Show / Hide 
Range on Protein: 498-703
Range on HMM: 1-209/270
Sequence Identity: 28% (63 aa)

FEIINQIGEGTYGQVYKARDK----DTGELVALKKV--RTDNE---KEGFPITAVREIKILRQL-NHDSVIRLHEIVTDKQDALDFKKDKGA--FYLVFE
 ... ..||| .|.|||.. |    .|.  || |..   .. |   .| |     ||.||..|| .|. ..||. ..|         ....    |.|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCT---------DQGEPNQIYIVME

YMDH-DLMGLLESG---LVNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHADDKT-RPYTNKVITLWYRPPELLL
|| | ||   | .      ... ..  ..  |  .|..| . .|. |||. . |.|.......| .||||||. . ||   |  ..  .     .|| . 
YMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECIN

GEERYGPAVDVWSCGCILGELFT
  . .  . |||| |  . |.||
YGK-FTTKSDVWSFGVLMWEIFT
Kinase CRK7.AA TyrKc 498-766 24 3.4e-16 39.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 498-766
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

FEIINQIGEGTYGQVYKARDKDTGELVALKKVRTDNEKEGFPITAVREIKILRQL--NHDSVIRLHEIVTDKQDALDFKKDKGAFYLVFEYMDH-DLMGL
 . . ..||| .|.|||.. |   . || |... |           ||..|...|  .|. ..||. ..|...    |    .  ..|.|||.| ||   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--F-MYIEPLMIVMEYMPHGDLKDY

LESGLVNFSEEHVRSFMKQLLDGLNYCHKRNFLHRDIKCSNILLNNKGHIKLADFGLARLYHAD-------DKTRP----YTNKVITLWYRPPELLLGEE
| .   ... ..  ||. |  .| .| |..|. |||. . |.|.......| .||||.|  . |       |  |.     .. .. .   .|| .  . 
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

RYGPAVDVWSCGCILGELFT--QRPIFQ------ANQELAQLELISRICGTPTPAVWPDV----IRLPLFNTMKPKKMYNRRLREEFSLLPKDAL
.. .. |||| |  . |.||  | |          |||. ..    .    |  .  | .        ... ||   ...   |  || . .. .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF