Gene MLCKd (Sea Urchin)
MLCKd
Sequence
Protein domains of MLCKd.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | MLCKd.AA | MLCK | 15-256 | 67 | 1.1e-225 | 602.09 | In-house | 1-243 (257) | Show / Hide |
Range on Protein: 15-256 Range on HMM: 1-243/257 Sequence Identity: 67% (164 aa) YIVKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIRAKDKEAVQREIDLMSELEHPSLMALIEAYQSSRQTVMILECITGGELFERIVDDTFDLTESEVI |...||||.||||||.||.|||||||||||..|....|||| |..||. | .|.|| |.....|...... |||.|.|.||||||||||. | |||.||| YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI SYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTGFQLKIIDFGLARKYEPDSD-VKVLCGTPEFVAPEVISYDAITPLTDMWSVGVICYVLLSGLSPFL .||||||.||.|||..||.|||||||||||..||. |.|||||||||||.|| . |||..||||||||||..|| ... |||||||||||.||||||||. HYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSPFM GDSDSETLNNVTMGEWDFEDEAFDGISNCAKDFISDLLVKDQR ||.| ||.||||..||||.||.||.||..|||||| |||||.. GDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKE |
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Kinase | MLCKd.AA | DAPK | 17-254 | 44 | 7e-118 | 326.3 | In-house | 1-248 (264) | Show / Hide |
Range on Protein: 17-254 Range on HMM: 1-248/264 Sequence Identity: 44% (111 aa) VKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIRAKDK------EAVQREIDLMSELE-HPSLMALIEAYQSSRQTVMILECITGGELFERIVDDTFD-L |||| |.| .| .| .||||| |||..| | . | .|| |.. || . | |.| . ...||| .||||| .. | . | MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL TESEVISYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTGFQ--LKIIDFGLARKYEPDSDVKVLCGTPEFVAPEVISYDAITPLTDMWSVGVICYVLL .| .... |.|| || ..| || ||||||.||| .| | .|||||||.|| .. .... ||||.||||...|..... |||||.||| |..| CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYIML SGLSPFLGDSDSETLNNVTMGEWDFEDEAFDGISNCAKDFISDLLVKD || |||||| ||. |.. ||..| |.. | ||||| ||||| SGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKD |
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Kinase | MLCKd.AA | Trio | 15-254 | 39 | 1.6e-111 | 287.14 | In-house | 1-242 (258) | Show / Hide |
Range on Protein: 15-254 Range on HMM: 1-242/258 Sequence Identity: 39% (97 aa) YIVKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIRAKDKEAVQREIDLMSELEHPSLMALIEAYQSSRQTVMILECITGGELFERIVDDTFDLTESEVI | ..||.| | |..| || .|.||.| ||| . |..|||.|..| ... | || .. | ..| . |. . ||| ...||| .... . . ..||||. YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFI-PYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLM-RWGSYCESEVK SYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTG--FQLKIIDFGLARKYEPD--SDVKVLCGTPEFVAPEVISYDAITPLTDMWSVGVICYVLLSGLS ||.|. .|. | . | |||.||||.| . . . |.||.||| | .. | . |.|||.|||.| . . . || ||.||. ||.||| | TYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSGIS PFLGDSDSETLNNVTMGEWDFEDEAFDGISNCAKDFISDLLVKD ||...|| ||. |. | .|... | ..|. ||.|| .|. | PFYDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQED |
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Kinase | MLCKd.AA | CAMK | 20-254 | 24 | 4.2e-105 | 339.68 | In-house | 1-409 (425) | Show / Hide |
Range on Protein: 20-254 Range on HMM: 1-409/425 Sequence Identity: 24% (101 aa) ELGKGKFGIVYRCEEKSTG------------KTWAAKYVKTIRAK----------------------------DKEAVQREIDLMSE-------LEHPSL .||.| ||.|..|..|.|. . .|.| ... ..| |.. |.|||..|. | || . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI MALIEAYQSSRQ-------------------TVMIL---ECITGGEL----FERIVDD--------------TFDLTESEVISYMRQICAGVQHMHHHNI |.|.|..... .|.. | ..|||| |..||. .. .||.|. |.|||| .|...| ||| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI MHLDLKPENIMCVNRTG---------------FQLKIIDFGLARKYEP------------------------DSDVKVLCGTPEFVA-PEVISY------ .|.|||||||..... . ...||||||.|.|..| . | |||||..| |||... VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM --------DAITPLTDMWSVGVICYVLLSGLSPFLGD-------------SDSETLNNVTMGEWDFEDEAFDG------------ISNC--------AKD . ..| .||||.|||.|..|.| .|| || .|.|.. ... |..||... |.. ||. .|| QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD FISDLLVKD .|. .|..| LIRKMLQVD |
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Kinase | MLCKd.AA | DAPK | 15-256 | 46 | 5.6e-103 | 297.85 | In-house | 1-250 (264) | Show / Hide |
Range on Protein: 15-256 Range on HMM: 1-250/264 Sequence Identity: 46% (116 aa) YIVKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIRAK------DKEAVQREIDLMSELE-HPSLMALIEAYQSSRQTVMILECITGGELFERIVDDTFD | . ||.| | | .| .| |||||| |||..| | . | . ||. |. || | ..| |.||| ..||||| . . YDMGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEKEC- LTESEVISYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTGFQ--LKIIDFGLARKYEPDSDVKVLCGTPEFVAPEVISYDAITPLTDMWSVGVICYVL |.| | .. || ||.||| .| |.|||||||| .| . ||||||||.. || ...| . |||||||||.. | . . |||||.||| |.| LNEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSIGVITYIL LSGLSPFLGDSDSETLNNVTMGEWDFEDEAFDGISNCAKDFISDLLVKDQR ||| |||||| ||| |.| . .|..| | |. ||||| ||||| . LSGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPK |
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Kinase | MLCKd.AA | CAMK1 | 15-254 | 36 | 8e-91 | 264.25 | In-house | 1-260 (276) | Show / Hide |
Range on Protein: 15-254 Range on HMM: 1-260/276 Sequence Identity: 36% (96 aa) YIVKEELGKGKFGIVYRCEEKST---GKTWAAKYV--KTIRAKDK----EAVQREIDLMS---ELEHPSLMALIEAYQSSRQTVMILECITGGELFERIV |....|.|.| |..||.|..|.| || .| |. |. .|.. ||...||. | .. || ...| |.| . ...| .||||||.||| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV DDTFDLTESEVISYMRQICAGVQHMHHHNIMHLDLKPENIMCVNR-TGFQLK--IIDFGLARKYEPDSD-VKVLCGTPEFVAPEVISY---DAITPLTDM . .. || . |.||. |..|| ..|.| ||||||. ... ....| |.||||......|.. | ||||..|||||. . .. || EKGN-YTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM WSVGVICYVLLSGLSPFLGDS-DSETLNNVTMGEWDFEDEAFDGISNC-AKDFISDLLVKD ||.||| |.|| | .|| ... |.| . .. .|..| .| ||. |||||. .|..| WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVD |
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Kinase | MLCKd.AA | Ciliate-E2a | 15-254 | 34 | 1.5e-80 | 236.85 | In-house | 1-259 (275) | Show / Hide |
Range on Protein: 15-254 Range on HMM: 1-259/275 Sequence Identity: 34% (89 aa) YIVKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIRAKDKE----AVQREIDLMSELEHPSLMALIEAYQSSRQTVMILECITGGELFERIVDDT-FDLT | .. ..|||.|| || . | ||| |.|... .. ... ....||..|..| || .. |.| |.. .. ...| . ||||...|. . |. YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE ESEVISYMRQIC-AGVQHMHHHNIMHLDLKPENIMCV--NRTG---FQLKIIDFGLARKYEPDSD--VKVLCGTPEFVAPEVISYDAI------TPLTDM . |. ..|.|. |...|| |||| |||||||. . .. ...||||||||... .|. ... |||| .|||||. . . . || IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM WSVGVICYVLLSGLSPFLGDSDSETLNNVTMGEWDFEDEA-FDGISNCAKDFISDLLVKD ||.||| | ||.| .|| | . .|.| .. . ||.. . .|. .||... .|.|| WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKD |
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Kinase | MLCKd.AA | DRAK | 17-254 | 39 | 1.8e-80 | 249.69 | In-house | 1-243 (259) | Show / Hide |
Range on Protein: 17-254 Range on HMM: 1-243/259 Sequence Identity: 39% (96 aa) VKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIR-AKD-KEAVQREID-LMSELEHPSLMALIEAYQSSRQTVMILECITGGELFE-RIVDDTFDLTESE |.|.||| .| .| .|.||. .|||..| | ..| .. . .|| || . | . | | | . ....|| .|||.|. . | ..| . TAKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKD VISYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTGFQ-LKIIDFGLARKYEPDSDVKVLCGTPEFVAPEVISYDAITPLTDMWSVGVICYVLLSGLSP |. |||| ||. .| || |||||| ||. . .||.|||..|. . ..| . |||..||||. .|| || .|||||.||. ||.|...|| VQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHISP FLGDSDSETLNNVTMGEWDFEDEAFDGISNCAKDFISDLLVKD |.|| || |. |. .| |...|. | ||| |.|.. FVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIK |
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Kinase | MLCKd.AA | Pkinase | 15-254 | 31 | 1.9e-77 | 268.37 | Pfam | 1-277 (293) | Show / Hide |
Range on Protein: 15-254 Range on HMM: 1-277/293 Sequence Identity: 31% (89 aa) YIVKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIRAKDKEAVQ----REIDLMSELEHPSLMALIEAYQSSRQTVMILECITGG----ELFERIV-DDT | ... .|.| || ||.| .|.|||..| | .| ..|... .. .|| .| .| || |........ |..|. || .||..| .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH FDL--TESEVISYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTGF--QLKIIDFGLARK--YEPDSDVKVLCGTPEFVAPEVIS-YDAITPLTDMWSV . .| |...||.||. |....| ..|.| |||||||...|. .||.|||||.. | ..| ...||||...||||| . ..| ||||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVICYVLLSGLSPFLGD------SDSETLNNVTMGEWDFEDEAFDGIS-----------------NCAKDFISDLLVKD |.|.| .|.| || |. .. . .... .....|. . . || .||||...| || GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD |
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Kinase | MLCKd.AA | CDPK | 15-255 | 36 | 1.3e-76 | 234.55 | In-house | 1-256 (271) | Show / Hide |
Range on Protein: 15-255 Range on HMM: 1-256/271 Sequence Identity: 36% (95 aa) YIVKEELGKGKFGIVYRCEEK-STGKTW-AAKYVKTIRAKDKE---AVQREIDLMSELEHPSLMALIEAYQSSRQTVMILE--CITGGELFERIVDDTFD |. |..|||| || |... .| .|. . | | .. | |||| ...||.....| || . | || .. ..| ||||||..|.. YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH- LTESEVISYMRQICAGVQHMHHHNIMHLDLKPENIM-CVNRTG----FQLKIIDFGLARKYEPD-----SDVKVLCGTPEFVAPEVI--SYDAITPLTDM .|| | ..|||| |...| .||.| |||||||. . . .. ...|.||.|...|.... . . |||| .||||. .|. | FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNE---KCDI WSVGVICYVLLSGLSPFLGDSDSETLNNVTMGEWDFEDEAFDGISNCAKDFISDLLVKDQ || ||| |.||.| || |..|.|....| |. .||.. .| ||. ||| |. .|..|. WSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDP |
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Kinase | MLCKd.AA | S_TKc | 15-255 | 32 | 1.6e-74 | 254.82 | SMART | 1-220 (231) | Show / Hide |
Range on Protein: 15-255 Range on HMM: 1-220/231 Sequence Identity: 32% (83 aa) YIVKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIRAKDKEAVQREIDLMSELEHPSLMALIEAYQSSRQTVMILECITG--GELFERIVDDTFD----- | . ...||| || ||.| .|.||. | | .| | ..|||..... || . |....|. |..|.. | |.||..|.. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP LTESEVISYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTGFQLKIIDFGLARKYEPDSDVKVLCGTPEFVAPEVISYDAITP-LTDMWSVGVICYVLL ..| .. .||.||| .....| |.|.| |||||||.. . ..||.||||||.. . .||||...||||. .. |.||.|.| | .| FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML SGLSPFLGDSDSETLNNVTMGEWDFEDEAFDGISNCAKDFISDLLVKD----------Q .| || . ...... | |||||. .|.|| | CGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTAEALQ |
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Kinase | MLCKd.AA | Ciliate-E2 | 15-255 | 21 | 2.3e-68 | 233.41 | In-house | 1-349 (365) | Show / Hide |
Range on Protein: 15-255 Range on HMM: 1-349/365 Sequence Identity: 21% (78 aa) YIVKEELGKGKFGIVYRCEEKSTGK--------------------TWAAKYVKTIRAKDKEAVQREIDLMSELE----------------HPSLMALIEA |.. . .|.| ||.||.|. ....| . ...|... ...|.. .||..| |.. || .. ..|. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YQ--SSRQTVMILECITGGELFERIVDD-TFD---------LTESEVISYMRQICA---------------GVQHMHHHN-IMHLDLKPENIMCVNRTGF .| . ...| . ||.||..| . .. .|| |.. .|.||. .....| | |.| |.|||||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ QLKIIDFGLARKYEPDSDVKV--------------------------------LCGTPEFVAPEVISYDA---------ITPLTDMWSVGVICYVLLSGL .|||||||..|| .|.. . .||||...|||.... . |.||.||| | .|.| -IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK SPFLGDSDSETLNNVTMGEWDFEDE--------------AFDGISNCAKDFISD----LLVKDQ || ... ...|| . .. .|. .||.|. .|.||. PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP |
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Kinase | MLCKd.AA | TyrKc | 15-251 | 22 | 1.2e-14 | 14.09 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 15-251 Range on HMM: 1-280/280 Sequence Identity: 22% (64 aa) YIVKEELGKGKFGIVYRCEEKSTGKTWAAKYVKTIRAKDKEAVQREIDLMSEL--EHPSLMALIEAYQSS-------RQTVMILECITGGELFERIVDDT ...|| | ||.||... | . | | .| .|. ||. .|..| .|| . .|. . .. . ...| .| | ... . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR FDLTESEVISYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTGFQLKIIDFGLARKYEPD------SDVKVLCG--TPEFV------APEVISYDAITP .|. .. .|.. ||..| .. |..|. | || |.. .. . || ||||.|. . | .|... . .. |||.| | |. PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT LTDMWSVGVICYVLLS-GLSPFLG-----DSDSETLNNVTMG-----EWD--------FEDEAFDGISNCAKD---------FISDLL .| || || .. ... | .| | |..| ...| | . || .. .. | . | ... KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | MLCKd.AA | Pkinase_Tyr | 15-212 | 26 | 2.7e-08 | 28.72 | Pfam | 1-216 (270) | Show / Hide |
Range on Protein: 15-212 Range on HMM: 1-216/270 Sequence Identity: 26% (57 aa) YIVKEELGKGKFGIVYRCEEK----STGKTWAAKYVKTIRAKD---KEAVQREIDLMSEL-EHPSLMALIEAYQ-SSRQ--TVMILECITGGELFERIVD . ..||.| || ||... | .|. . | | .| .. .|. ||. .|..| || . |. . ... ...| .| | . . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK D---TFDLTESEVISYMRQICAGVQHMHHHNIMHLDLKPENIMCVNRTGFQLKIIDFGLARKYEPDSDV-KVLCGTPEF----VAPEVISYDAITPLTDM || .. ... .||..| .. . .|. | || |.. |.... . || |||||| ..|. .. |.. . |||.|.| | .| HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCL-VTENN-VVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDV WSVGVICYVLLS-GLSP-F || || .. ... | .| . WSFGVLMWEIFTYGEQPTY |