Gene MARK3 (Sea Urchin)

MARK3

Species: Sea Urchin
Alias: Spk102, SPU_008218, MARK3
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MARK3.AA Protein None 742 None Fasta, JSON
MARK3.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of MARK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MARK3.AA MARK 29-280 57 1.9e-179 591.05 In-house 1-262 (262) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-262/262
Sequence Identity: 57% (151 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQLNP-SSLQKVYREVKIMKLLDHPNIVKLFEVIE--TDKT-LYLAMEYASGGEVFDYLVAH--GR
|...||||.|..|||||| |..||..|||||..|..||.  ....|.||..|||.||||||.|||.|||  | .. .|| ||||||||..||..||  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

MKEKEARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDL--NIKIADFGFSNEFTIGCKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLV
..|.|||. ||||||||.|||.|..||||.|.||.|.|..   ||||.|||||.... |.||.||||.|||.|||.|..|.||||.||.|||||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

SGSLPFDGQN--LKELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
.|..||||..  .|||....|||||.||...|..|.||..|.|..|| .|. .| |||..||
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase MARK3.AA CAMKL 29-280 48 1.9e-170 548.27 In-house 1-297 (297) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-297/297
Sequence Identity: 48% (145 aa)

YRLIKTIGKGNFAKVKLAKH-IPTGKEVAIKIID--KTQLNPSSLQK-----------VYREVKIMKLLD---HPNIVKLFEVIETDKT------LYLAM
||..||.|||.|.|||||.| . ||..|||||||  |....| ....           ..||..|||.|.   ||||.||.|||||...      .|| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASGGE--VFDYLVAH----GRMKEKEARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDL--NIKIADFGFSNEFT-I----GCKLDTFCGSPPYA
||.||||   |||.|.|    |||.|.|||  ||||||||.|||....||||.|.||.|||..   ||||.||||||... .    | ||.||||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFQG--KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK---------ELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
|||.|||  |.||||.||.||.|||||..| | ||||.....         ....... ....|....| ||..|... |. || ||. .. ||...||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase MARK3.AA QIK 29-280 57 4.3e-164 551.44 In-house 1-272 (272) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-272/272
Sequence Identity: 57% (156 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQLNPSSLQKVYREVKIMKLLDHPNIVKLFEVIETDKTLYLAMEYASGGEVFDYLVAHGR------
| . .|||||||| ||||.|. | ..||||||||.||. . |||.||||.|||.|.||.|.||..|.|||. .|. .||.|.|| ||||..|||      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------MKEKEARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFGFSNEFTIGCKLDTFCGSPPYAAPELFQGKKYDGPEVD
              |.|.||| .| ||.|||.|||.. .|||||||||.|||...||||||||||| |. |  | |.||||||||||.|.||.||||.||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
.||.||.|| ||.|.|||||..|..||.||| ||.||||.||.||| | .. | ..|..|   . |.. .||
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase MARK3.AA AMPK 29-280 50 2.7e-144 431.27 In-house 1-254 (254) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-254/254
Sequence Identity: 50% (127 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQLNPSSLQ-KVYREVKIMKLLDHPNIVKLFEVI-ETDKTLYLAMEYASGGEVFDYLVAHGRMKEK
| . ||||.| | |||...|| ||..|||||..|. .  .. . .. ||..|.||. ||.|..|.||| || . ... |||.|||| ||| | |||..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFGFSNEFTIGCKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
||.  | ||.|.| |||.  .|||||| ||||||.. ||||.||| ||  . | .| | |||| |||||. .||.| |||||.|| ||||| .. | |||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
| .|  .|  ... |.| || ..|.....|.|. |  .| ||.  . |....| 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase MARK3.AA CAMK 34-280 31 1.2e-142 462.9 In-house 1-425 (425) Show / Hide 
Range on Protein: 34-280
Range on HMM: 1-425/425
Sequence Identity: 31% (134 aa)

TIGKGNFAKVKLAKHIPTG------------KEVAIKIIDKTQLN--------------------------PSSLQKVYREVKIMKL-------LDHPNI
|.|.|.|.||||..|. |.            ..||||||||..|                           |.....|.||..|||.       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLFEVIE------------TDKT--------LYLAM---EYASGG----EVFDYLVAH---------------GRMKEKEARAKFRQIVSAVQYCHQKR
.||.||.|            | ..        .|. |   ||.|||    ..|||.|.|               ||..|.|||  ||||.|||.|||.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKAENLLLDKD-----------------LNIKIADFGFSNEFTI------------------------GCKLDTFCGSPPYAA-PELFQG-----
.|||||| ||.|||..                  ||||.||||.|.|.                         | |. ||||.|.|.| ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KKYDGPEVDVWSLGVILYTLVSGSLPFDGQ-------------NLKELRERVLRGKYR-IPFYMST-----------------------DCE
        |.|.||..|.||.|||||....| .||.|              |..|| |....|||. .|.|.|.                       .| 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLLKRFLMLNPAKRAMLETIMKDKWM
.|... |  .| ||. .| .....||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MARK3.AA NuaK 29-280 49 3.1e-140 371.62 In-house 1-252 (252) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-252/252
Sequence Identity: 49% (124 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQL-NPSSLQKVYREVKIMKLLDHPNIVKLFEVIETDKTLYLAMEYASGGEVFDYLVAHGRMKEKE
|...|| ||| . |||||  . ||.||||| | |     .  . .. ||..||  |.||.|.. .|| |    . . |||||||| .||.   ... |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFGFSNEFTIGCKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD
||  |||||||| |||. |..||||| || |||.. |.|||||| || .  .  | |||||| || ||   |. | ||||| |||||.|||.| |..|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
|.. |.|   . .|.|. |   |. |. |    || || .|| .. | .  |.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase MARK3.AA NIM1 29-280 42 1.5e-114 337.9 In-house 1-258 (258) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-258/258
Sequence Identity: 42% (110 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIID--KTQLNPSSLQKVYREVKIMKLLDHPNIVKLFEVIETDKTLYLAMEYASGGEVFDYLVAHGRMKEK
||. . || ||| ||||. |  | . |||||.|  || .    .    ||.  |  . |||||.|.||.||   ..| ||||.||| . .    | . | 
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

EARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFGFSNEFTI----GCKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSG
..   | ||||||.  | . .||||.|||| ..     .|..|||||         . .|.|||||||||||||||   | |. |||| ||..||  . |
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

SLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
  ||      ..   .| |.| || | |  |  | .. |   |. |.  . .|.. ||
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase MARK3.AA BRSK 29-280 53 3.2e-112 379.11 In-house 1-254 (254) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-254/254
Sequence Identity: 53% (135 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQLN--PSSLQKVYREVKIMKLLDHPNIVKLFEVIETDKTLYLAMEYASGGEVFDYLVAHGRMKEK
||| || |||   .|||  |  ||| |||||| |  |   .| |.|| ||. |||| |||.. |...| |. | ||| .|. |||| |||||  ||.. |
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFGFSNEFTIGCKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
|||  ||||.||. .|| . . ||||| |||||| . ||||||||       .  |.| |||| || ||  .| ||||   |||| ||||| |  | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
|  || .| |.| || . .| .   || .||.  .  .|.||  |. | |  | 
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase MARK3.AA S_TKc 29-280 34 5e-110 372.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQLNPSSLQKVYREVKIMKLLDHPNIVKLFEVIETDKTLYLAMEYASG--GEVFDYLVAHGR----
|.....|||| |.||....|. ||..||||||.         ....||..|.|  .|||||||..|... . ||. |||..|  |..|||.. .||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--MKEKEARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFGFSNEFTIGCKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLV
  . | .||  ..||..|..|||.....||||| ||.|||.  .|||.|||.. ..      .||||.| | |||..   .|.....|.||.|.||| ..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMK-------DKWM
.|  ||.  ..... ....          | .. ..... |  .|.||     ...       . |.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MARK3.AA SNRK 29-280 48 9.69999999999e-105 343.94 In-house 1-254 (254) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-254/254
Sequence Identity: 48% (122 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQLNPSSLQKVYREVKIMKLLDHPNIVKLFEVIETDKTLYLAMEYASGGEVFDYLVAHGR-MKEKE
| | ||.|.| || ||||.|. ||. ||.|.||||..   |  ....||. |||  |||||.|.|||.|   ||| .|   |....||.. | . ..|. 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARAKFRQIVSAVQYCHQKRVVHRDLKAENLL-LDKDLNIKIADFGFSNEFTIGCKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
||  |.||. |..||||..||||||| || .  .|   .|. ||||||.|  | ||.|.|||  |.|||.  | .|| | ||.|||||||| || | .||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
.  |  |   ...  || .|  .|..| .|... |. .| ||| || |    |.
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase MARK3.AA TSSK 29-280 37 1.9e-101 333.72 In-house 1-289 (289) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-289/289
Sequence Identity: 37% (108 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKE----------------VAIKIIDKTQLNPSSLQK-VYREVKIMKL-LDHPNIVKLFEVIETDK-TLYLAMEYAS
| . |.||.|..|||..| .  . ..                |||||||..   .  |.|   || .||.  |.||||....| .||     |. ||||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGEVFDYLVAH------GRMKEKEARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFGFSNEFTIGC------KLDTFCGSPPYAAPELF
.| ...|  ..      |...|..||. |||.||||.||| . ||||||| ||.||||. |||..||||..... .       .. |||||  ||||| .
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

QGKKYDGPEVDVWSLGVILYTLVSGSLPFDG--QNLKELRERVL-RG-KYRI--PFYMSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
.|..||.  .||||.|||||..| |..|||   .|.. . ...  .. ....      |..| .|... | ..| .|. .. |... ||
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase MARK3.AA Pkinase 29-280 33 4.7e-98 336.87 Pfam 1-293 (293) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-293/293
Sequence Identity: 33% (99 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQLNPSSLQKVYR--EVKIMKLLDHPNIVKLFEVIETDKTLYLAMEYASGG----EVFDYLV--AH
|.....||.|.|..|....|. |||.||.|||.|   ... .|   |  |..||| |.|||||.|... |... .|. |||. ||    . |||.   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRM--KEKEARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNI----KIADFGFSN---EFTIGCKLDTFCGSPPYAAPELFQGKKYDGPEVDVWS
|..   |.|..  ..||.....|||.....||||| ||.|.|.. .|    ||.|||..    .   .  ..||||.|.|.|||. .| .|.||.||.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVILYTLVSGSLPFDGQ------NLKELRERVLRGKYRIPFY---------------------MSTDCENLLKRFLMLNPAKRAMLETIMKDKWM
.|.||| ...| .||.|.      . ... .|....... ...                     .| .|  ..|. | ..|.||   | |....|.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MARK3.AA Pkinase_Tyr 29-171 31 1.2e-26 90.92 Pfam 1-156 (270) Show / Hide 
Range on Protein: 29-171
Range on HMM: 1-156/270
Sequence Identity: 31% (50 aa)

YRLIKTIGKGNFAKVKLAKHI----PTGKEVAIKIIDKTQLNPSS--LQKVYREVKIMKLL-DHPNIVKLFEVIE-TDKT--LYLAMEYASGGEVFDYLV
 ...|..|.|.| .|....       |. .||.|.. | .  ..   ...  ||.|||| | .|||||.|  |.   ..   .|. |||. .|   ||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AH----GRMKEKEARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFG
.|    .. . |.     .|| .. .| ..|. .|||| | | |..... .||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase MARK3.AA TyrKc 29-279 25 1.5e-26 95.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 29-279
Range on HMM: 1-280/280
Sequence Identity: 25% (73 aa)

YRLIKTIGKGNFAKVKLAKHIPTGKEVAIKIIDKTQLNPSSLQKVYREVKIMKLL--DHPNIVKLFEVIETD-------KTLYLAMEYASGGEVFDYLVA
 .|.|..| |.| .| ... .    .||.| . .       ..  .|| .||. |  .|||||.|. |. ..       . |.. |||...|   ||| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HGR-MKEKEARAKFRQIVSAVQYCHQKRVVHRDLKAENLLLDKDLNIKIADFGFSNEFTIG------CKLDTF----CGS--PPYA--APELFQGKKYDG
|..  . |.      || .  .| |.|...|||| | | |..... .||.||| | . . .       .  .     .|    |.   ||| .. .|.  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-

PEVDVWSLGVILYTLVS-GSLPFDG-----QNLKELRERVLRG-KYRIPFY--------MSTDCENLLKRFLMLNPAKRAMLETIMKDKW
.. |||| || .. . . |  |  |      . .|..|.| .|   ..| .        ....  .. |.  . .|..|   ..| ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase MARK3.AA Pkinase_Tyr 208-246 34 0.032582 8.12 Pfam 196-236 (270) Show / Hide 
Range on Protein: 208-246
Range on HMM: 196-236/270
Sequence Identity: 34% (14 aa)

DVWSLGVILYTLVS-GSLP-FDGQNLKELRERVLRGKYRIP
|||| || .. ... |  | . |    |. |.. .  || |
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP
UBA_CAMKL MARK3.AA UBA_CAMKL 301-338 51 7.9e-17 58.37 In-house 1-41 (41) Show / Hide 
Range on Protein: 301-338
Range on HMM: 1-41/41
Sequence Identity: 51% (21 aa)

DERRIETMTGM--GFKRKEIEDSLRNHKY-DEHYATYLLLG
||..|. |  |  ||.|.||..|||| || ....|||.||.
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL
UBA MARK3.AA UBA 301-338 28 1.1e-08 36.11 SMART 1-38 (38) Show / Hide 
Range on Protein: 301-338
Range on HMM: 1-38/38
Sequence Identity: 28% (11 aa)

DERRIETMTGMGFKRKEIEDSLRNHKYDEHYATYLLLG
.| .|.....||| | |....||. ....  |...|. 
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS
UBA MARK3.AA UBA 300-336 23 2.9e-05 22.83 Pfam 1-38 (38) Show / Hide 
Range on Protein: 300-336
Range on HMM: 1-38/38
Sequence Identity: 23% (9 aa)

YDERRIETMTGM-GFKRKEIEDSLRNHKYDEHYATYLL
 ||  ....  | || . . .. ||......  |.. |
IDEEMVKQLMEMTGFSMMQCKKALRACNNNVERAVEWL