Gene RIO3 (Sea Urchin)

RIO3

Species: Sea Urchin
Alias: RIO3, Spk052, SPU_005063
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO3

Sequence

Name Sequence Type Origin Length Description Download
RIO3.AA Protein None 326 None Fasta, JSON

Protein domain

Protein domains of RIO3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIO3.AA RIO3 164-325 61 5.5e-75 252.23 In-house 1-167 (254) Show / Hide 
Range on Protein: 164-325
Range on HMM: 1-167/254
Sequence Identity: 61% (103 aa)

HSTAEMAVDSRTRIMLYKLVNNGMLDSITGTISTGKEAVVIHAYGGQIDD-----HIIPPECALKVFKTTLNEFKKRDQYIRNDYRFRARFKKQNPRKFI
||||| ||| .||...||.|| |||..||| |.||||.||.||||| ..|     ..|| .||.||||||||||| ||.||..|.||. || | ||||  
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH

QMWAEKEMHNLNRMREAGIRCPEVVLLRKHILVMSYIGKDQKAALKLKHVKFSVSEAQCVYEECLEV
.|||||||||| ||. ||| || ||||.|||||||.||.||  | ||| ||.   | .  | . | .
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHL
Kinase RIO3.AA RIO 167-324 35 7.5e-66 224.8 In-house 1-164 (276) Show / Hide 
Range on Protein: 167-324
Range on HMM: 1-164/276
Sequence Identity: 35% (58 aa)

AEMAVDSRTRIMLYKLVNNGMLDSITGTISTGKEAVVIHAYGGQIDD-----HIIPPECALKVFKTTLNEFKKRDQYIRNDYRFRARFKKQNPRKFIQMW
.| ..| .||...||.|| ||. |....|..|||... |....  .|      .|| |||.|...|....|| |. |.  ...|. |. | |.|. . .|
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AEKEMHNLNRMREAGIRCPEVVLLRKHILVMSYIGKDQKAALKLKHVKFSVSEAQ-CVYEECLE
|||||.|. |. ..|. |||......|.|||. |..||..| |.. .. . .|.   || .|..
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMC
Kinase RIO3.AA RIO1 202-326 40 1e-53 167.96 Pfam 1-128 (200) Show / Hide 
Range on Protein: 202-326
Range on HMM: 1-128/200
Sequence Identity: 40% (54 aa)

VVIHAYG-GQIDDHIIPPECALKVFKTTLNEFKKRDQYIRNDYRFRARFKKQNPRKFIQMWAEKEMHNLNRMREAGIRCPEVVLLRKHILVMSYIG-KDQ
.| |||.    .|     |||.|...|....|||.. |.  |.|||.|. ..|.|. ..||||||..||.||.|||..||.......|.|||..|| || 
NVYHAYSMEDGKD-----ECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDG

KAALKLKHVK----FSVSEAQCVYEECLE--VR
 .| .||.|     .| .||...|.|...  .|
WPAPRLKDVEMELELSEEEAEEIYDEIIREYMR
Kinase RIO3.AA RIO1 170-315 40 2.7e-38 129.9 In-house 2-143 (225) Show / Hide 
Range on Protein: 170-315
Range on HMM: 2-143/225
Sequence Identity: 40% (59 aa)

AVDSRTRIMLYKLVNNGMLDSITGTISTGKEAVVIHAYGGQIDDHIIPPECALKVFKTTLNEFKKRDQYIRNDYRFRARFKKQNPRKFIQMWAEKEMHNL
 .| |||..|.|..  |..  | | ||||||. | ||            | | |..||    || |. |.   .|||    | |||| | .|||||| ||
VIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRA----EYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNL

NRMREAGIRCPEVVLLRKHILVMSYIGKDQKAALKLKHVKFSVSEA
 |.  . | ||| . .. ..|.|..|||| .|| .|| . .. ...
KRIYQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQ
RIO RIO3.AA RIO 160-326 30 4.3e-33 117.17 SMART 1-241 (253) Show / Hide 
Range on Protein: 160-326
Range on HMM: 1-241/253
Sequence Identity: 30% (73 aa)

EKKEHSTAEMAVDSRTRIMLYKLVNNGMLDSIT--GTISTGKEAVVIHAYGGQIDDHIIPPECALKVFKTTLNEFKKRDQYIRNDYRFRARFKKQNPRKF
.|....|.| ..|.|||  |||.||.|....|.  |.|||||||.| ||.|| .|.   . ||| |...|...|||... ||  | ||. .. . |.|| 
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDK--NGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKM

IQMWAEKEMHNLNRMREAGIRCPEVVLLRKHILVMSYIGKDQKAALKLKHVKFS--------------VSEAQCVYEEC-------------LE------
...|||||..||.|| |||..||.....|.|.|||..||.|...|..|| |.                ...    |.||             .       
VRLWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDEN

-----------------------------------------VR
                                         ..
DCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCD