Gene BCKDK (Sea Urchin)
BCKDK
Sequence
Protein domains of BCKDK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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BCDHK_Adom3 | BCKDK.AA | BCDHK_Adom3 | 73-228 | 28 | 2e-63 | 219.84 | Pfam | 1-199 (199) | Show / Hide |
Range on Protein: 73-228 Range on HMM: 1-199/199 Sequence Identity: 28% (57 aa) VRLTPATLLYTGK-SPDGNHLLRSAQYLHKELPVRVAHRIAEFRGLPFIVGCNPTILHVHELYIRAFHLLSE-F--------------PSIRDMDT---- .|. . ... |. | ..|..|||..|.|||.| |||| |.. ||... ..| |..|...|...|. | | | | ...... TPLSLRQMMQFGRPNPCEKTLFKSAQFCHEELPIRLAHRIRELQNLPYGLNKMPHIQQVYNWYYQSFEELRECFPKPISELKHLRYYEPPPKTLEDWLHD -ERQYCKMVKTLLDDHK-DVVTHLAEGFRECR-KHI----TDES----LIHNFLDRILTSRLGI---RMLAEHHLFL-----HQDK----NDSIGIIAT ....|.|.....|.| .||...|.|..|.. ... ... |. |||| ..|| || |||...|. | |. . .| .||| | YNEKFCDMLRDIKDRHDRNVVPTMAQGVLEWKCRYYGQDNQPDDLHWFQIQYFLDRFYMSRIGINFIRMLIGQHIALFEFNYHNPHHFEHPDYVGIICT |
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Kinase | BCKDK.AA | PDHK | 389-480 | 36 | 1.9e-32 | 109.56 | In-house | 50-140 (140) | Show / Hide |
Range on Protein: 389-480 Range on HMM: 50-140/140 Sequence Identity: 36% (35 aa) ISDRGGGIPHSLLKKVFQYHFTTAND---DESVSDNGGALGTMIEAVNQPT-AGPLCGFGFGLPVSKAYAEYLGGSISLETMQGIGTDVYLRLRHI .||||||.|| . .| |...|| | ..| | | . ... |.|. |||.|||.. .||.|..|. | |.|.|||....|. . MSDRGGGVPHRKIDRLFNYMYSTAPRSTQDPRMSPLFGHL-----DMHETSRAAPMHGFGYGLPICRLYAKYFQGDLQLYSMEGYGTDAVIYLKAL |
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Kinase | BCKDK.AA | PDHK | 269-316 | 45 | 3.3e-24 | 80.87 | In-house | 1-48 (140) | Show / Hide |
Range on Protein: 269-316 Range on HMM: 1-48/140 Sequence Identity: 45% (22 aa) YIIQPLDYMLPELLKNAMRATIESHLDTPMNLPDVVITIASNEVDFII |. .|..||.||.|||||||.|.|.|.| |.|......| ...| .| YVPMHLYHMLFELFKNAMRATMEHHEDRPYNYPPIKVMVALGDEDLTI |
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Kinase | BCKDK.AA | HATPase_c | 389-480 | 21 | 2.3e-10 | 38.33 | Pfam | 42-120 (120) | Show / Hide |
Range on Protein: 389-480 Range on HMM: 42-120/120 Sequence Identity: 21% (21 aa) ISDRGGGIPH------SLLKKVFQYHFTTANDDESVSDNGGALGTMIEAVNQPTAGPLCG--FGFGLPVSKAYAEYLGGSISLETMQGIGTDVYLRLRHI ..| | ||| .. ..|. ...| .| . | .|.|| ......| .||.|..|. | || . ..| VEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--------------------SR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE |
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Kinase | BCKDK.AA | PDHK | 437-480 | 45 | 3.3e-10 | 33.76 | In-house | 82-125 (125) | Show / Hide |
Range on Protein: 437-480 Range on HMM: 82-125/125 Sequence Identity: 45% (20 aa) AGPLCGFGFGLPVSKAYAEYLGGSISLETMQGIGTDVYLRLRHI | || |||.|||... || | | . | |.| ||| . |. . AAPLAGFGYGLPICRLYAKYFQGDLKLYSMEGYGTDAVIYLKAL |
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Kinase | BCKDK.AA | PDHK | 328-358 | 45 | 1.3e-09 | 30.15 | In-house | 43-73 (140) | Show / Hide |
Range on Protein: 328-358 Range on HMM: 43-73/140 Sequence Identity: 45% (14 aa) DNDVLNRISDRGGGIPHSLLKKVFQYHFTTA | | ..||||||.|| . .| |...|| DEDLTIKMSDRGGGVPHRKIDRLFNYMYSTA |
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Kinase | BCKDK.AA | PDHK | 269-308 | 40 | 3.7e-07 | 22.74 | In-house | 1-39 (125) | Show / Hide |
Range on Protein: 269-308 Range on HMM: 1-39/125 Sequence Identity: 40% (16 aa) YIIQPLDYMLPELLKNAMRATIESHLDTPMNLPDVVITIA |. | || || |||||||.|.| . . .| . . .. YVPSHLYHMLFELFKNAMRATVEHHENRK-IYPPIKVMVT |
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Kinase | BCKDK.AA | HATPase_c | 269-481 | 13 | 2.5e-05 | 24.96 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 269-481 Range on HMM: 1-130/130 Sequence Identity: 13% (31 aa) YIIQPLDYMLPELLKNAMRATIESHLD---TPMNLPDVVITIASNEVDFIISFGWQNQLIEYDNDVLNRISDRGGGIPHSLLKKVFQYHFTTANDDESVS .| .| .||.|| ..| |.| | .. . .. ||. . GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------------------------------------------------------- DNGGALGTMIEAVNQPTAGPLCGISDRGGGIPH------SLLKKVFQYHFTTANDDESVSDNGGALGTMIEAVNQPTAGPLCG--FGFGLPVSKAYAEYL ..| | ||| .....|. ..|.. .. .. .. | .| ||...|...| . --------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS-------------RMCPDSRSRKYGGGLTGLGLSICKRIVEQH GGSISLETMQGIGTDVYLRLRHID ||.|..| | ....|. GGTIWVE------TTFTFTLPLER |
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Kinase | BCKDK.AA | HATPase_c | 269-368 | 13 | 8.9e-05 | 18.87 | Pfam | 1-84 (120) | Show / Hide |
Range on Protein: 269-368 Range on HMM: 1-84/120 Sequence Identity: 13% (15 aa) YIIQPLDYMLPELLKNAMRATIESHLDTPMNLPDVVITIASNEVDFIISFGWQNQLIEYDNDVLNRISDRGGGIPH------SLLKKVFQYHFTTAN--D .| .. .|. ||...| |. . . ... . ..| ...| | ||| .. ..|. ...| . . GDPDRLHQVVWNLVDNAIKHTPEG--------GHITVRVHRDD-----------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR DESVSD--NG .... .| -RKYGGGLTG |
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Kinase | BCKDK.AA | PDHK | 334-358 | 44 | 0.000709 | 10.9 | In-house | 48-72 (125) | Show / Hide |
Range on Protein: 334-358 Range on HMM: 48-72/125 Sequence Identity: 44% (11 aa) RISDRGGGIPHSLLKKVFQYHFTTA ..||||||.| . . | | . || KMSDRGGGVPLRKIDRLFNYMYSTA |
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Kinase | BCKDK.AA | PDHK | 389-412 | 45 | 0.000892 | 10.54 | In-house | 49-72 (125) | Show / Hide |
Range on Protein: 389-412 Range on HMM: 49-72/125 Sequence Identity: 45% (11 aa) ISDRGGGIPHSLLKKVFQYHFTTA .||||||.| . . | | . || MSDRGGGVPLRKIDRLFNYMYSTA |