Gene BRD (Sea Urchin)

BRD

Species: Sea Urchin
Alias: SPU_006720, BRD, Spk039
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Atypical
Family: BRD

Sequence

Name Sequence Type Origin Length Description Download
BRD.AA Protein None 1643 None Fasta, JSON

Protein domain

Protein domains of BRD.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Bromodomain BRD.AA Bromodomain 1-68 42 1.1e-23 79.53 Pfam 21-89 (89) Show / Hide 
Range on Protein: 1-68
Range on HMM: 21-89/89
Sequence Identity: 42% (29 aa)

HPVDPTKLALPDYFKIIKTPMDLGTIKKRLESIYYH-SAKECISDFNLMFTNCYVYNKPGEDVVLMAQA
||||| .  .|||..|||.|||| ||...|.. .|. . .| . |..||..||. ||.|. ..  .|. 
HPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK
BROMO BRD.AA BROMO 3-82 37 3.9e-21 77.45 SMART 20-118 (118) Show / Hide 
Range on Protein: 3-82
Range on HMM: 20-118/118
Sequence Identity: 37% (37 aa)

VD-----------------PTKLA--LPDYFKIIKTPMDLGTIKKRLESIYYHSAKECISDFNLMFTNCYVYNKPGEDVVLMAQALEKLFLTKVAQMPQ
 .                 ...    .|||..|||.||||.||||.||. .|.|..| . ||.|||.||. ||.|. .|  ||. |.|.|. | ...|.
DHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVYKMAKKLQKFFEEKWREFPP
BROMO BRD.AA BROMO 295-404 42 8.8e-44 152.68 SMART 1-118 (118) Show / Hide 
Range on Protein: 295-404
Range on HMM: 1-118/118
Sequence Identity: 42% (50 aa)

LTAQLKYCYGVIKELMSKKHSA---------YAWPFFKPVDADVLGLHDYHEIIKTPMDMGTVKVKLENRDYKNANDFAANVRLIFTNCYKYNPPDHDVV
  . .|.|. . ||.|..||.          ||||| .|||.. |...||..|||.|||..|.| ||||. |... .|.. ..|.|.||..||.||..| 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

GMARKLQNVFEVKFAKMPD
 ||.|||..|| |....|.
KMAKKLQKFFEEKWREFPP
Bromodomain BRD.AA Bromodomain 302-390 35 2.4e-26 88.29 Pfam 1-89 (89) Show / Hide 
Range on Protein: 302-390
Range on HMM: 1-89/89
Sequence Identity: 35% (33 aa)

CYGVIK--ELMSKKHSAYAWPFFKPVDADVLGLHDYHEIIKTPMDMGTVKVKLENRDYK-NANDFAANVRLIFTNCYKYNPPDHDVVGMARK
|  ...  ..|...    ..||..||| |. .. ||..|||.|||. |.. ||.|. |. |  .| . ..|...||..||.||...  .|||
CDQIMDMKYIMEHP---ICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK