Gene ADCK1 (Sea Urchin)
ADCK1
Sequence
Protein domains of ADCK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | ADCK1.AA | ABC1-B | 144-260 | 44 | 5.3e-54 | 185.71 | In-house | 1-125 (125) | Show / Hide |
Range on Protein: 144-260 Range on HMM: 1-125/125 Sequence Identity: 44% (56 aa) EDLGVLADDLFSDFSEEPVGTASLAQVHTALLKDGTMVAVKVQHPNVKLYSEVDMSTVEFLLNAVARIFP------EFELLWLAQEMREKLPIELDFVQE .||| .| || |...|...||||||| | |.||. ||||||||... . || . |... .. || ||.. |. .| . || |||| | KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDMMMMELFVKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYNE GKNAEKVAKMLK---HFKFLKVPGIY ..||||.. |.| ||.||.|| |. ARNAEKCRQMFKKFKHFDFLYVPRIH |
|||||||||
Kinase | ADCK1.AA | ABC1 | 144-260 | 41 | 9.4e-51 | 172.92 | Pfam | 1-126 (126) | Show / Hide |
Range on Protein: 144-260 Range on HMM: 1-126/126 Sequence Identity: 41% (52 aa) EDLGVLADDLFSDFSEEPVGTASLAQVHTALLKD-GTMVAVKVQHPNVKLYSEVDMSTVEFLLNAVARIFPE-----FELLWLAQEMREKLPIELDFVQE |.|| ...|. |.|||...||.|||| | ||| | ||||||||.|| ...|. ........|.|.||. |.| |...|.|. || |||. .| EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE GKNAEKVAKMLKHF---KFLKVPGIY .||.|.......|. ....|| .| AKNMERFRENFRHWHRQPWVYVPKVY |
|||||||||
Kinase | ADCK1.AA | ABC1 | 144-260 | 42 | 1.8e-48 | 167.34 | In-house | 1-123 (123) | Show / Hide |
Range on Protein: 144-260 Range on HMM: 1-123/123 Sequence Identity: 42% (53 aa) EDLGVLADDLFSDFSEEPVGTASLAQVHTALLKDGTMVAVKVQHPNVKLYSEVDMSTVEFLLNAVARIFP-----EFELLWLAQEMREKLPIELDFVQEG .||| .| || |.|.|...||.|||| | ||||. ||||||||.|. . |. . |...... || .|.| |. .| .. || |.|| |. QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA KNAEKVAKMLK--HFKFLKVPGIY .||||.. ..| |..|..|| |. RNAEKCRQLFKKFHWPFFYVPRIH |
|||||||||
Kinase | ADCK1.AA | ABC1-A | 157-191 | 57 | 6.9e-12 | 37.62 | In-house | 1-35 (216) | Show / Hide |
Range on Protein: 157-191 Range on HMM: 1-35/216 Sequence Identity: 57% (20 aa) FSEEPVGTASLAQVHTALLKDGTMVAVKVQHPNVK | | | || ||| |.||||. ||||.| | |. FEEMPFACASIGQVHQAVLKDGREVAVKIQYPGVA |
|||||||||
Kinase | ADCK1.AA | ABC1-C | 302-324 | 60 | 1e-06 | 16.05 | In-house | 124-146 (307) | Show / Hide |
Range on Protein: 302-324 Range on HMM: 124-146/307 Sequence Identity: 60% (14 aa) MYSEMIFVNGFVHCDPHPGNVLI | |||| ||| | ||||.|. MLLKMIFVDNFVHADLHPGNILV |
|||||||||
Kinase | ADCK1.AA | S_TKc | 156-445 | 13 | 2.9e-05 | -99.74 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 156-445 Range on HMM: 1-231/231 Sequence Identity: 13% (43 aa) DFSEEPVGTASLAQVHTALLKD-GTMVAVKVQHPNVKLYSEVDMSTVEFLLNAVARIFPEFELLWLAQEMREKLPIELDFVQEGKNAEKVAKMLKHFKFL ...| . ..|. . |. | ||.|. . |.. |.. .. . . . |.. .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------------------------EHIRREIQILKK--HHPNIVKLYDVFQD- KVPGIYWKHSTSRVLTMEYCNG--GKVDNKEYMDQMGIDVNQ--ITKNLGKMYSEMIFV-------NGFVHCDPHPGNVLIRHNDKKEVEIVLLDHGLYQ .. . ||||.| | . ..|....| .. .. . | |. .|..|.| | |.|. . .| . | || ----------DHLYMVMEYCDGDLGDL--FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLAR TLTDEFRLDYSRLWQS--ILAADLEGIKHYSM------ALGAGQMYGIFACMLTARS-WDSLAEGIDKKERSAQEDREVREHAALYMSEITQLLNMVPR- | . .. . . .| .|. ..| |.. ||. . .. ... . . | ..|.. |. QL---TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGC-----ILYEMLCGYPPFP----QMQMMFKKIG-------SPEAKD-FIRKCLQKDPEK ----QMLL---LLKTNDLL . | . | . RPTAEALQDEWDIKCHPWF |
|||||||||
Kinase | ADCK1.AA | ABC1-A | 241-280 | 37 | 0.078207 | 2.46 | In-house | 85-124 (216) | Show / Hide |
Range on Protein: 241-280 Range on HMM: 85-124/216 Sequence Identity: 37% (15 aa) AEKVAKMLKHFKFLKVPGIYWKHSTSRVLTMEYCNGGKVD . | .|| | || . .|.|||||| | .| MQKFRQLLKDWPFFYVPHVIDEYCTDRVLTMELMYGFPID |
|||||||||
Kinase | ADCK1.AA | ABC1-C | 181-188 | 87 | 0.148494 | 0.06 | In-house | 1-8 (307) | Show / Hide |
Range on Protein: 181-188 Range on HMM: 1-8/307 Sequence Identity: 87% (7 aa) VAVKVQHP ||||| || VAVKVLHP |