Gene 5838 (Tetrahymena)

5838

Species: Tetrahymena
Alias: TTHERM_00580440, 5838, PreTt05838, 327, 78.m00210, 3733.m00104
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
5838.AA Protein None 1108 None Fasta, JSON
5838.kin_dom Protein Kinase Domain None 250 None Fasta, JSON
5838.NA RNA None 3327 None Fasta, JSON

Protein domain

Protein domains of 5838.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 5838.AA MST 28-277 53 3e-199 639.1 In-house 1-254 (254) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-254/254
Sequence Identity: 53% (136 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKILKINSDLNSHLNEETTLSDMNSKYIVKLYDKYIDAKNKEIWLVIEFCNMGSLADVINITGQTFFEAEIA
...|...|||..|.||.||.|.|.||||||....|.||.....|........||||||.|..|.||||...|.|.|.|.|||..|...||..|..|..||
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIA

CILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVASCKSD----ADTFVGSPYWLSPEQLNKQKYTNKVDIWALGICIIEMAEGMPPYGDL
|||...||||.|||.|...|||.|..|||||.|||.||.||||.....|    ..|..|.|||..||.....||..|.|||.|||..||||||||||.|.
CILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDI

RPTSAMKMIKQNPIVNFQDPQQFSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
.|..||.||.|.|...|.||.|.|.|.|.|.|.|||.|||.||||||||.|.|.
HPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 5838.AA STE20 28-277 40 4e-136 458.51 In-house 1-288 (288) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-288/288
Sequence Identity: 40% (116 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKI----VAIKILKINSD------LNSHLNEETTLSDMNSKYIVKLYDKYIDAKN--KEIWLVIEFCNMGSLADVIN
||.. .||||..|.|| |..| |...    ||||.......      ......|.  ... ....||| |. |.  ..   |.|.|.|.|. ||| |...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---ITGQ-----TFFEAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVASCKSD-----AD----TFVGSPYWLSPEQLNK----
   ..|.     .. |..||.|. .|||||||||.||..|||.|..||||. .||.||.||||..  ..      .    ||||.|||..|| ...    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-QKYTNKVDIWALGICIIEMAEGMPPYGDLRPTSAMKMIK--QNPIVNFQD--PQQFSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
 ..|..|.|||.|||..|||||| ||| |. |..|| ||   |||   ..|  | ..|.|...|. .|||..||.|.||.|||.| |.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 5838.AA STE 28-277 29 1.1e-109 370.72 In-house 1-359 (359) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-359/359
Sequence Identity: 29% (107 aa)

YEKVYRIGQGAFGVVYQAIDK------FTDKI---------VAIKILKINSD-------------------LNSHLNEETTLSDMN--SKYIVKLYDKYI
.|.. .||.||||.||.|...       |...         .|||.......                   ... |.|  .....|  ...||| |. |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DAK-----NKEIWLVIEFCNMGSLADVIN---ITGQT----------FFEAEIACILDNVLQG-LDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVAS
.       . |.|.. |... ||| |.|.   ..|..          | | .||.|.  .|.| |.|||..|..|||.|.|||||     .||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

CKSD--------------------ADTFVGSPYWLSPEQLNK------QKYTNKVDIWALGICIIEMAEGMPPYGDLRPTSAMKMIKQN-----------
. .|                     .||||.| | .|| ...      ..|. |.||| ||..|||||.| ||. |. |..|| || .|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PIVNFQD-----------------PQQFSDELNNFLCHCLQINPEDRWTAEQLLN--HDFF
    |.  ..|                 | ..|.|...|. .|||..|..|.||.|||.  | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 5838.AA S_TKc 28-277 33 1.4e-85 291.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-231/231
Sequence Identity: 33% (88 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKILKINSDLNSHLNEETTLSDMNSKYIVKLYDKYIDAKNKEIWLVIEFCNM--GSLADVINITGQ-----T
||..  ||.||||.||....| |..||||||.|     .. ..|   |.  . ..|||||| . |   .....| |.|.   |.| |.|   |       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FFEAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVASCKSDADTFVGSPYWLSPEQLNKQKYTN-KVDIWALGICIIEMAEGMPP
| | ......  ....|.|.|... .||||| .||||..  . |..|||.|      .||.|.|....|| |   .|.  |.|.|..|....||. | ||
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPP

YGDLRPTSAMKMIKQNPIVNFQDPQQFSDELNNFLCHCLQINPEDRWTAEQLLN-------HDFF
.    .   .|.|.             |.|. .|...||| .||.|.|| ..|.       | .|
FP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 5838.AA PAKA 28-277 37 3e-81 276.24 In-house 1-260 (260) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-260/260
Sequence Identity: 37% (99 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKI--VAIKILKINSDLNSH---LNEETTLSDMNSKYIVKLYDKYIDAKNKEIWLVIEFCNMGSLADVINITGQ---
|...  ||||| | || |... | .   |||| .... . ..    .||  .. . . | ||. .| |.   . |.|.|.|. . |.| |||  . .   
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQ-PKKELIINEILVMKECKHKNIVNYIDSYLV--DDELWVVMEYMEGGCLTDVITQCCNIQC

-TFFEAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVA----SCKSDADTFVGSPYWLSPEQLNKQKYTNKVDIWALGICIIEMA
 .. |. ||...  .||||...|..|| |||.|| ||||. .|. |. ||| .      ..  .| || ||| .|| .....|  ||||| ||| .|||.
NYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMI

EGMPPYGDLRPTSAMKMIKQNPIVNFQDPQQFSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
|| ||| .  |  ||  | .| .  ..||  .|.|...||  ||......|..|..||.| |.
EGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 5838.AA YSK 28-277 40 6.1e-81 243.37 In-house 1-257 (257) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-257/257
Sequence Identity: 40% (105 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKILKINS---DLNSHLNEETTLSDMNSKYIVKLYDKYIDAKNKEIWLVIEFCNMGSLADVINIT--GQTFF
. |  .|| | ||.|| .||. | ..|||||.   .   .      | . ||.  | || | |  |   |   .| . |.|  ||..| .     || | 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYL--KDTKLWIIMEYCGGGSCLDLMKPKYVGQ-FD

EAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVASCKSDA----DTFVGSPYWLSPEQLNK--QKYTNKVDIWALGICIIEMAEG
|  || ||  .|.||||||..   ||| |.||.||...|. || |||||.   |     .||||.|||  ||   .   .|  |.||| |||  .||| |
EKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKG

MPPYGDLRPTSAMKMIKQNPIVNFQDPQQFSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
 ||| |. |  .|  |  |.    .. ...|. . .|   ||  .||.| .|..|| | | 
EPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 5838.AA Pkinase 28-277 30 3.6e-76 264.15 Pfam 1-293 (293) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKILKINSDLN----SHLN--EETTLSDMNSKYIVKLYDKYIDAKNKEIWLVIEFCNMG----SLADVIN-I
|... .||.|.||.||....| | ||||.||.|  ..      .|..  |   .  .|...||.||| . |  ...|..| |.|..|    .|.|.|   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

TGQTF--FEAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEA----KLSDFGVASC----KSDADTFVGSPYWLSPEQLN-KQKYTNKVDIWA
 . .|   | |. ...  .|.||.|.|..  .|||||..|||..|.|.     |..|||.| .    .| ..||.|.|....|| ..  |.|. |||.|.
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGICIIEMAEGMPPYGDL----RPTSAMKMIKQNPIVNFQDPQQFS---------------------DELNNFLCHCLQINPEDRWTAEQLLNHDFF
.|. ..||. | ||. .     .  . |.||...    .  . . .                     .|.  |.. ||. .|..|.||||.|.|..|
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 5838.AA PAKL 97-277 43 8.6e-70 238.17 In-house 71-256 (256) Show / Hide 
Range on Protein: 97-277
Range on HMM: 71-256/256
Sequence Identity: 43% (80 aa)

EIWLVIEFCNMGSLADVINITGQTFFEAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVAS---CKSD--ADTFVGSPYWLSPEQ
..|   ..|  ||  |.. ... |. |..|. || ..| || |||     ||| |.||||||  .  |. |||| .      |  |   .|.|||  || 
HYWILMDYCSLGSINDMMESCCKTLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEI

LNKQKYTNKVDIWALGICIIEMAEGMPPYGDLRPTSAMKMIKQNPIVNFQDPQQFSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
.||| | ||.||| ||| .||||.| ||  |..|. ||.||   |   | .|  .| ..|.||  |..  || || . .|| |.| 
INKQNYNNKCDIWSLGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 5838.AA TAO 28-277 37 3.5e-67 218.42 In-house 1-254 (254) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-254/254
Sequence Identity: 37% (96 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKILKINSDLNSH-----LNEETTLSDMNSKYIVKLYDKYIDAKNKEIWLVIEFCNMGSLADVINITGQTFF
.. .  || |.|| || | || |...|||| .. .           . |   |  ..   ...    |.  ...  |||.|.| .|| .|....  . . 
FQDLREIGHGSFGAVYFARDKHTEEVVAIKKMSYSGKQSHEKWQDIIKEVRFLQQVKHPNCIEYKGCYL--REHTCWLVMEYC-LGSASDILDVHKKPMQ

EAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVASCKSDADTFVGSPYWLSPE---QLNKQKYTNKVDIWALGICIIEMAEGMPP
| ||| |   .||||.|||. ...|||.| .|||| ..|  ||.||| || .. |..||| |||. ||    .   .|..|||.|.|||  ||.||  ||
EVEIAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP

YGDLRPTSAMKMIKQNPIVNFQDPQQFSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
. ..   ||.  | ||     |  ...||.  .|. .|||  |..| .||..| |.| 
LFNMNAMSALYHIAQNDSPTLQ-QNEWSDCFHQFVDKCLQKMPQERPSAEECLRHEFV
Kinase 5838.AA SLK 28-277 34 2.7e-61 205.49 In-house 1-259 (259) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-259/259
Sequence Identity: 34% (89 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKILKINS--DLNSHLNEETTLSDMNSKYIVKLYDKYIDAKNKEIWLVIEFCNMGSLADVINITGQTFFEAE
.| .  .| |||| ||.| .| .... | |...|..  .|. .. |   ||...  .|||||. |    ....|..||||. | .  ..   ...  |  
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYY--YDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQ

IACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVASCKSDA----DTFVGSPYWLSP-----EQLNKQKYTNKVDIWALGICIIEMAEG
|. .   ....|..||.|. .|||||  |||.  .|. .| ||||.  .       |||.| |||. |     | .  | |  |.|||.||| .||||..
IQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQM

MPPYGDLRPTSAMKMIKQNPIVNFQDPQQFSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
 ||. .. |   .  |..      . | ..| | ..|| .||. .|. |||..||..| ..
EPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase 5838.AA ULK 28-277 25 1.8e-60 207.18 In-house 1-329 (329) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-329/329
Sequence Identity: 25% (85 aa)

YEKVYRIGQGAFGVVYQAIDKFT----DKIVAIKILKINS-DLNSHL-----------NEETTLSDMN----SKY----IVKLYDKYIDAKNKEIWLVIE
|..  ..|.|.||.||....| |    ...||.|.. ... . ....           ||  ..  ..    .|.    |||||| . ..... |... |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCNMGSLADVINITGQ---------TFFEAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNE------------GEAKLSDFGVA-SCKSD-----
.|| | | . |.  .          .. | |.  ..   |.|. .|||.  .|||.| .|||..|             | .|..||| | .. .|     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-ADTFV------GSPYWLSPEQLN----KQKYTNK-VDIWALGICIIEMAEGMPPYGDLRPTSAMKMIKQNPIVN------------FQDP-----QQFS
 . |.|      |.|.  .|. |.    ...|... .||| ||. . ||  | ||.    ...  ..|.|. | |            .| |     .|.|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

DELNNFLCHCLQINPEDRWTAEQLLNHDFF
.|. ...  .||....|| . |.|.|| .|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 5838.AA Ciliate-E2 28-277 24 4.1e-60 205.04 In-house 1-365 (365) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

YEKVYRIGQGAFGVVYQAID-----------------------KFTDKIVAIKIL-----KINSDLNSHL----------NEETTLSDMNSKYIVKLYDK
|...  ||||.||.||.. .                       |.. ||.|.||.     .. .  .. .          ||   |. .|...|.|.|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YIDAKNKEIWLVIEFCNMGSLADVINITGQTFF----------EAEIACILDNVLQ---------------GLDYLHKNH-RMHRDLKSANILLNNEGEA
... ... | || |.|. |.| | |..  . ..          | ||. |   .||               .| |||...  .|||.|  |||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFGVAS--------------CK---------------------SDADTFVGSPYWLSPEQLNKQK---------YTNKVDIWALGICIIEMAEGMPP
|..||| .               ||                       ..|..|.|. ..|| ||..|         |. |.|||.||... ||  | ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

YGDLRPTSAMKMIKQ-NPIVNFQ--------------DPQQFSDELNNFLCH----CLQINPEDRWT-AEQLLNHDFF
.        .. ||| .   ...              .... |.|  ...      .|| .|| | | .||.||| .|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 5838.AA TyrKc 28-277 23 2.6e-17 57.17 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKILKINSDLNSHLNEETTLSDM--NSKYIVKLYDKYIDAKN-------KEIWLVIEFCNMGSLADVINITG
 ..   .| ||||.||... |     ||.| || .. .   ..|   ..    . . ||.||   .  .        . ...| |..  |.| | .  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLY--GVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

QTFFEAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVASCKSDA-------DTFV-----GSP-----YWLSPEQLNKQKYTNKV
 ..  ..   .   . .| .|||...  ||||   |.|..... .| |||| .    |        |. .     |.       |..|| .|. |.| | 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIWALGICIIEMAE-GMPPYGD-----LRPTSAMKMIKQNPIVNFQDPQQ------FSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
|.|. |.|. |.   |..|| .     . .. ... .||       .          .||. .    | . .|||| | ...  |..|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 5838.AA Pkinase_Tyr 28-171 25 9.4e-14 47.2 Pfam 1-158 (270) Show / Hide 
Range on Protein: 28-171
Range on HMM: 1-158/270
Sequence Identity: 25% (41 aa)

YEKVYRIGQGAFGVVYQAIDK----FTDKIVAIKILKINSDLNS-----HLNEETTLSDM-NSKYIVKLYDKYI-DAK-NKEIWLVIEFCNMGSLADVIN
 ..   .|.||||.||... |     |.  ||.|.|| ...         ..|  ... . . . ||.||   . . . | .|..| |..  |.| |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLR

IT---GQTFFEAEIACILDNVLQGLDYLHKNHRMHRDLKSANILLNNEGEAKLSDFGVA
     .| .   .. ..   . .|..||. ..  ||||   |.|..... .| .||| |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 5838.AA Pkinase_Tyr 186-277 26 1.8e-09 32.69 Pfam 180-270 (270) Show / Hide 
Range on Protein: 186-277
Range on HMM: 180-270/270
Sequence Identity: 26% (25 aa)

WLSPEQLNKQKYTNKVDIWALGICIIEMAE-GMPP-YGDLRPTSAMKMI-KQNPIVNFQDPQQFSDELNNFLCHCLQINPEDRWTAEQLLNHDFF
|..|| .|  |.| | |.|. |... |.   |. | | .. ..  ...| ...       |.  .||. . ...| . .|||| | ...  | ..
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC--PENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase 5838.AA PAKL 28-61 44 0.006325 7.14 In-house 1-34 (256) Show / Hide 
Range on Protein: 28-61
Range on HMM: 1-34/256
Sequence Identity: 44% (15 aa)

YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKILKI
.|     |||..| || || | |    ||| . |
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEI