Gene 17909 (Tetrahymena)

17909

Species: Tetrahymena
Alias: PreTt17909, 302, 3745.m00022, 17909, TTHERM_00933100, 168.m00077
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
17909.AA Protein None 947 None Fasta, JSON
17909.kin_dom Protein Kinase Domain None 252 None Fasta, JSON
17909.NA RNA None 2844 None Fasta, JSON

Protein domain

Protein domains of 17909.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 17909.AA MST 13-264 62 1.8e-211 678.53 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-254/254
Sequence Identity: 62% (158 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVMLVNEDIFQISKEISILQNCKNQNIVGYFGSFF--KDNAIWLVTEYCEGGSALDLIKIIQRTFNEQEIS
|||. .||||.||.|.||..||..|..|||.. ||||...|.|||||.|.||...||.|.||.|  |.|..|.|.|||..||..|..||.|||.|||.|.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIA

AILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQTLMGTPYWMSPEVLGNSKYNNKTDIWSLGITAIELAEGEPPYSNI
.|||..|.|||||||||||||||||||||||..||.||||||||...|.|.|...|..||||||.|||....||..|.|||||||||||.|||.||||.|
CILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDI

HPFRAMFAIKKNPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
||.||||.|...||.....|.||||||.|||.|||......|..|..||.||||
HPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 17909.AA STE20 13-264 47 7.4e-153 514.12 In-house 1-288 (288) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-288/288
Sequence Identity: 47% (137 aa)

FDIICILGQGNYGKVFKALCKQDKKE----YAIKVMLVNED------IFQISKEISILQNCKNQNIVGYFGSFFKD----NAIWLVTEYCEGGSALDLIK
....  .|||.||||.|| .|. ...    .|||.| ....      .  | |||||...||..||| |.||..||    . .|.| |||.|||..|..|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---IIQR-----TFNEQEISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTY----TNA-EKQTLMGTPYWMSPEVLGN----
   ....     ..||..|..|....| ||.||| |..|||||||.||||.|.||.|||||||.|  |     |.. ...|. ||||||.|||.      
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-SKYNNKTDIWSLGITAIELAEGEPPYSNIHPFRAMFAIK--KNPPQGLSN--PTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
 ..|..|.|||||||||||.|||||||...||.|||| |   .|||  |..  |..||.|| |||.|||. | . ||.|..||.||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 17909.AA STE 13-264 32 7.2e-126 424.46 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-359/359
Sequence Identity: 32% (119 aa)

FDIICILGQGNYGKVFKALCK------QDKKE---------YAIKVMLVNED-------------------IFQISKEISILQNCK--NQNIVGYFGSFF
...| ..|.|..|.|.||...      . ...         .|||.| ....                   . || |||.|...|.   .||| |.|..|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KD-------NAIWLVTEYCEGGSALDLIK---IIQRTFN----------EQEISAILYQALLG-LQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSA
|.       . .|.. ||..|||. |.||   ......|          |..|..|..| | | |.|||....||||||..||||     .||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

EQTYTNA----------------EKQTLMGTPYWMSPEVLGN------SKYNNKTDIWSLGITAIELAEGEPPYSNIHPFRAMFAIKKN-----------
  | ..|                . .|. ||| ||.|||. .      ..|. | ||||||.|.||.|.|.||... ||.||||.| .|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPQGLSN-----------------PTQWSQEFSDFVKKCLTLDSNLRPSAKDLLS--HPFI
    ||  | .                 |..||.|| ||..|||. | | ||.|..||.  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 17909.AA YSK 13-264 46 6.1e-118 356.79 In-house 1-257 (257) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-257/257
Sequence Identity: 46% (120 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVM---LVNEDIFQISKEISILQNCKNQNIVGYFGSFFKDNAIWLVTEYCEGGSALDLIKI-IQRTFNEQE
| .    | |..| |.|.  .. .. .|||.       ..|  | .|| .|  |. ..|  |.||. ||  .| . ||| |||.|||.|      | |. 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

ISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQTLMGTPYWMSPEVLGN--SKYNNKTDIWSLGITAIELAEGEPP
|. ||   |.|| ||| ..|||||||| |.||.|.|. ||.||||..  | |    .|  |||||| |||     |.|. | |||||||||.|.| ||||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

YSNIHPFRAMFAIKKNPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
|.  || |.|| | ||.|  |.   ..|  | .||  ||  | . |||||.||.| ||
YCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 17909.AA PAKL 13-264 49 1.2e-109 370.59 In-house 1-256 (256) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-256/256
Sequence Identity: 49% (126 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVMLVNED--IFQISKEISILQNCKNQNIVGYFGSFFKD-NAIWLVTEYCEGGSALDLIKIIQRTFNEQEI
| .   |||| || |.||. |      ||||. . |   |  |.|||.|| .||..||| ||||     | .|   .||  ||  |.....  |.|| .|
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

SAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNA-EKQTLMGTPYWMSPEVLGNSKYNNKTDIWSLGITAIELAEGEPPYS
| || |.|.|| |||    ||||||| |||||| .  |.||||||     .   ..  . |||||| ||..    |||| |||||||||||.|.|.|| .
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHY

NIHPFRAMFAIKKNPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
 . | |||  |   ||  .|||  || .| ||. .|.. | . |.|. |||.||||
DMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 17909.AA PAKA 13-264 42 5.1e-96 325.29 In-house 1-260 (260) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-260/260
Sequence Identity: 42% (111 aa)

FDIICILGQGNYGKVFKALCKQDKKE--YAIKVM-LVNEDIF-QISKEISILQNCKNQNIVGYFGSFFKDNAIWLVTEYCEGGSALDLIKIIQR----TF
.. .  .|||  |.|..|  .. ..|   |||.| . |..    |  ||... .||..||| |  |.  |  .|.| || |||.  |.|.  ..    ..
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

NEQEISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQTLMGTPYWMSPEVLGNSKYNNKTDIWSLGITAIELAEGE
.|. |.... . | ||...|... ||||||  ||||.  |. |..|||  |. |  . ...|  ||||||.|||.   .|. | ||||||| |||..|||
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGE

PPYSNIHPFRAMFAIKKN--PPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
||| |  | |||. | .|  |.  . .|. ||||| ||..||| .|   |.||..||.|||.
PPYLNEPPLRAMYLIATNGKPD--IKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 17909.AA S_TKc 13-264 31 1.7e-94 321.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVMLVNEDIFQISKEISILQNCKNQNIVGYFGSFFKDNAIWLVTEYCEG--GSALDLIKIIQR-----TFN
..|. ..|.| .|||.|.  | .....|||..       .| .||.||.. .  ||| ....|   . ...|.|||.|  |. .|.||  .|      |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

EQEISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQTLMGTPYWMSPEVLGNSKYNN-KTDIWSLGITAIELAEGE
| ..  ..|| ...|.|.|... ||||.|  ||||.|  . |..|||....         |. |||..|.||||   .|.  | |.||.|.. .|.. |.
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

PPYSNIHPFRAMFAIKKNPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLS-------HPFI
||..  .... .  |.             |.|. ||..|||. | . ||.| ..|        ||..
PPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 17909.AA NinaC 13-264 43 1.5e-87 297.18 In-house 1-267 (267) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-267/267
Sequence Identity: 43% (115 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVMLVNEDI-FQISKEISILQN-CKNQNIVGYFGSFFKDN-----AIWLVTEYCEGGSALDLIKII---QR
. |.   |.| ||||||.. |.. .  |.|..   .|.   |  |  ||.  |   |.| ..| ..|        .|.| ||| |||. |..| .    |
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

TFNEQEISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQTLMGTPYWMSPEVLG-----NSKYNNKTDIWSLGITA
  .|. |. ||. |..||| || |. ||||.|  ||||   |  || ||||||  . |   . |  |||.|| |||       .. |    |.|||||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IELAEGEPPYSNIHPFRAMFAIKKNPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
|||. |.||  ..|| |||| |  |||  |  |..|.||| ||. .||. |   ||.  ..| ||||
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase 17909.AA Ste20-DD1 13-264 44 3.1e-87 296.13 In-house 1-268 (268) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-268/268
Sequence Identity: 44% (118 aa)

FDIICILGQGNYGKVFKA--LCKQDKKEY-----AIKVMLVN----EDIFQISKEISILQNCKN-QNIVGYFGSFFKDNAIWLVTEYCEGGSALDLIKII
| |. . ||| .| |     . |.|         |.| . .|    |.     ||| || |      || | | . |.|    | |||.||| || ... 
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMC

QRTFNEQEISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQTLMGTPYWMSPEVLGN----SKYNNKTDIWSLGIT
  .  | .| ||.||   || ||| |. .||||||||.|.|. | .||||||||.    .    .|  | |||||||.         |  | ||||||||
SKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGIT

AIELAEGEPPYSNIHPFRAMFAIKKNPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
|||.||  ||  |. | |  | |   .|  |  |  || || ||.| ||  .  .|||| .||.||||
AIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase 17909.AA KHS 13-264 43 2.8e-86 290.21 In-house 1-258 (258) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-258/258
Sequence Identity: 43% (113 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVMLVN--EDIFQISKEISILQNCKNQNIVGYFGSFFKDNAIWLVTEYCEGGSALDLIKIIQRTFNEQEIS
....  .| | || |.||  .| ..  |.||. ..  .|.  | .|| ....|.  |||.||||... . .|.. ||| |||  |. ..     .|  |.
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP-LSELQIA

AILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQTLMGTPYWMSPEVLGNSK---YNNKTDIWSLGITAIELAEGEPPY
 .  ..| ||.||| ..|.|||||  ||||...|. |||||||||. | | | ..  .|||||| |||    .   ||.  |||..|||||||||  || 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

SNIHPFRAMFAIKK---NPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
 ..||.||.| . |   .||. | . ..||| | .||| .|| ..  ||.|. ||.|||.
FDLHPMRALFLMTKSNFQPPK-LKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase 17909.AA SLK 13-264 40 3.9e-83 280.31 In-house 1-259 (259) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-259/259
Sequence Identity: 40% (105 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVMLV--NEDIFQISKEISILQNCKNQNIVGYFGSFFKDNAIWLVTEYCEGGSALDLIKIIQRTFNEQEIS
..||  || | .||| ||  |. |.  | |.. .  .|..     || || .||  |||. ..... || .|.. |.|.||    ..  ....  |. | 
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

AILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQTLMGTPYWMSPEV-----LGNSKYNNKTDIWSLGITAIELAEGEP
 . .. . .|..||.|| ||||.||||||.   |. .|||||||| .. |   . | .|||||| |||     .    |  |.|||||||| ||.|..||
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PYSNIHPFRAMFAIKKNPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
|.... | | .. |.|  |  | .| .||.||.||.||||  | . |.....|. |...
PHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase 17909.AA Pkinase 13-264 29 1.8e-74 258.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVMLVNEDIFQISK------EISILQNCKNQNIVGYFGSFFKDNAIWLVTEYCEGG----SALDLIK-IIQ
. |. ..|.|..|.|.|.  | . |..|.|.. . ..  .  .      ||.|.....  ||| ....|  .. |..|.||||||    .  |.|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RTF--NEQEISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEA----KLADFGVSAEQ-TYTNAEKQTLMGTPYWMSPEVLG-NSKYNNKTDIWSL
..|   |.|.  ..|| | ||.|.|... ||||.|  |||....|.     |..|||...   .  |   .|. |||..|.|||.  ...|  | |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITAIELAEGEPPYSNI----HPFRAMFAIKKNPPQGLSNPTQWS---------------------QEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
|.. .|.. |.||...     .  . |. |... .  |. . .|.                     .|. ||.|.||..| . ||.|...| ||..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 17909.AA TyrKc 13-264 22 2.3e-32 114.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

FDIICILGQGNYGKVFKALCKQDKKEYAIKVMLVNEDIFQISKEISILQNC--KNQNIVGYFGSFFKD-------NAIWLVTEYCEGGSALDLIKIIQRT
   . .|| |..|.|.|.  |    . |.|..  .  .  . .|..|. .   ...|||  .|   ..         ...|.||...|. .| ..  ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

FNEQEISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYT----NAEKQTLM----GTP-----YWMSPEVLGNSKYNNKTDI
.. ..   . .|.  | .|||... ||||. | |.|..|.. .| .||| | . .       ...   .    |.       ||.||..  .|.. |.|.
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSLGITAIELAE-GEPPYSN-----IHPFRAMFAIKKN-----PPQGLSNPTQ----WSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
|| |..  |.   |..||..     . .....  .|.      || ..  |       ..|  .  |.|   | . ||. ...  | ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 17909.AA Pkinase_Tyr 13-264 24 2.7e-31 106.6 Pfam 1-270 (270) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-270/270
Sequence Identity: 24% (67 aa)

FDIICILGQGNYGKVFKALCK----QDKKEYAIKVM--LVNED---IFQISKEISILQNC-KNQNIVGYFGSFF-KDNA--IWLVTEYCEGGSALDLIKI
  ..  ||.|..|.|.|. .|    ..| . |.|..     ..   .    .|..|. .  ...||| . |    ..    |..|.||...|. ||  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

I---QRTFNEQEISAILYQALLGLQYLHDNKKIHRDIKAGNILLNEKGEAKLADFGVSAEQTYTNAEKQ-TLMG---TPY-WMSPEVLGNSKYNNKTDIW
    .. .. ...  . .|   |..||.... ||||. | |.|..|.. .| .||| .     .| .   .  |    |  ||.||.. ..|.. |.|.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGITAIELAE-GEPP-YSNIHPFRAMFAI-KKNPPQGLSNPTQWSQEFSDFVKKCLTLDSNLRPSAKDLLSHPFI
| |..  |.   || | | .. ... . .| ...    .  |   ..|  |  |.|   | . ||. ...  | ..
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL