Gene 29763 (Tetrahymena)

29763

Species: Tetrahymena
Alias: PreTt29763, 898, 14.m00330, TTHERM_00170550, 29763
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
29763.AA Protein None 1153 None Fasta, JSON
29763.kin_dom Protein Kinase Domain None 274 None Fasta, JSON
29763.NA RNA None 3462 None Fasta, JSON

Protein domain

Protein domains of 29763.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 29763.AA STE11-Unclassified 215-488 47 1.4e-182 612.81 In-house 1-308 (308) Show / Hide 
Range on Protein: 215-488
Range on HMM: 1-308/308
Sequence Identity: 47% (152 aa)

WQSGEVLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYN--QKDRQEK-IQQIQSEIEALRNFSDKNIVRYIGIK--KSETSINIFLEYVPGGSISSLLYR
||.||..|.||||||...||..|||||||||..|..||  |.|.|.. ||.||.|...|.....||||.|.|..  |.|..||||.||.|||||.|.|..
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

YGKFNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGNCKLADFGSAK---------------------KIVEEK----GHNDSIRGTPY---
||.|.|..|.|.|.|||.||.|||.|.||||||||||.|.|.||.|||.|||.||                     ||....    .|..|..||||   
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

WMAPETIK---Q-LGS-----GSIGCTVIEMATAKPPWADKSP---IQAMFYIANAQQPPPIPEHLSPVCKDFISKCLKYQNQIELVDLTKTQQILFLQF
|||||.||   |  ..     .|.|||||||||.|.||.....   ..|...|....|.|.||||||||| |||| |         .........|...|
WMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVC-DFIS-C---------WISQECKDFLRKCF

RINPNDRYNVRQLLNHPFI
.|.|..|....|||.||||
QIDPKKRPTANQLLQHPFI
Kinase 29763.AA STE11 215-450 45 3.7e-145 488.53 In-house 1-287 (303) Show / Hide 
Range on Protein: 215-450
Range on HMM: 1-287/303
Sequence Identity: 45% (131 aa)

WQSGEVLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYNQ--KDRQEKIQQ------IQSEIEALRNFSDKNIVRYIGIKK---SETSINIFLEYVPGGSI
||.||..|.|.||.| ..||.||||.|||||..|...||  .|.....|.      ||.||. ..... ||||||.|..    .. ..|||.||.||||.
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

SSLLY-RYGK--FNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGN-CKLADFGSAKKIVEEKGHNDS----------IRGTPY--------
||.|. ..|.  |.|..|||.|.|||.|| |||.| ||||||||||.|.|.||| |||||||.||.....  ....          ..||||        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPETIKQLG---SG------SIGCTVIEMATAKPPWADKS--PIQAMFYIANA-QQPPPIPEHLS------PVCKDFISKCLKYQ
|||||.||| |    |      |.|||||||||.||||.. .  ...|||.|. . ...||||||.|      . |.||...|....
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHD
Kinase 29763.AA STE 215-449 31 7.8e-100 337.97 In-house 1-340 (359) Show / Hide 
Range on Protein: 215-449
Range on HMM: 1-340/359
Sequence Identity: 31% (109 aa)

WQSGEVLGTGSFGQVILGMNID---------------TGEFMAVKQVHIGGYNQKDRQ------------EKIQQIQSEIEALRNFS--DKNIVRYIGIK
|.  |..| |.||.| ..||..               |||.||.||...   |.|| .            |..|||. ||. .....   .|||.|.|  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

KSE-------TSINIFLEYVPGGSISSLLYRY--------------GKFNETLIRKFTQQILKG-LEYLHAHEIIHRDIKGANVLVDKDGNCKLADFGSA
  |       ....|..||..|||..... ..              ..|.|..|.....||||| |.||| | |||||||.||.|.     .||.||| .
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

KKIVEE----------------KGHNDSIRGTPYWMAPETIKQLGSG------------SIGCTVIEMATAKPPWADKSPIQAMFYIANA----------
......                ....... ||| ||||| |.| |.|            |.|||.||||| ||||.| .| .|||.|..           
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----QQPPPIPE-------------------HLSPVCKDFISKCLKY
    ..|||.|.                   ..|| .||||.|||..
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQK
Kinase 29763.AA MEKK15 215-447 42 4.2e-78 265.78 In-house 1-245 (264) Show / Hide 
Range on Protein: 215-447
Range on HMM: 1-245/264
Sequence Identity: 42% (104 aa)

WQSGEVLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYNQKDRQEKIQQIQSEIEALRNFSDKNIVRYIGIKKSETSINIFLEYVPGGSISSLLYRYGKFN
|. |..|| | .| |  |.  .||  .||||| .   ...  ... ...| |.. |.    |||| |.|.   .  .|||...||||||||.. |.|  .
WKKGNILGKGAYGTVYCGL-TNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIINRFGPLD

ETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGNCKLADFGSAKKIVEE--KGHN----DSIRGTPYWMAPETIKQLGSG------SIGCTVIE
|.   |.|.|||.| .|||   ..||||||.||..   |  || ||| ||..  .   . .     |.|||||||||| |.  | |      |||||| |
EMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGRKSDIWSIGCTVFE

MATAKPPWADKSPIQAMFYIANA-QQPPPIPEHLSPVCKDFISKCL
||| ||||||  .. |||||    .  |..|.. |   ..|.  ||
MATRKPPWADMDRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCL
Kinase 29763.AA S_TKc 215-488 26 1.1e-74 255.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 215-488
Range on HMM: 1-231/231
Sequence Identity: 26% (77 aa)

WQSGEVLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYNQKDRQEKIQQIQSEIEALRNFSDKNIVRYIGIKKSETSINIFLEYVPG--GSISSLLYRYGK
.. ....| |.||.| .. ...||. .|.|...             ..|..||. |..   .|||.....  . ... ...||..|  |.  ... ..|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------FNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGNCKLADFGSAKKIVEEKGHNDSIRGTPYWMAPETIKQLGS-----GSIGCTVI
      |.|  .|....||...|||.| | |||||.| .|.|.|.  . |..|||.|...       ... |||..|||| . . |       |.||...
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILY

EMATAKPPWADKSPIQAMFYIANAQQPPPIPEHLSPVCKDFISKCLKYQNQIELVDLTKTQQILFLQFRINPNDRYNVRQLLN-------HPFI
||.. .||.     .|.|| .             || .||||.|||..                      .|..|. . ..|.       ||..
EMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQK----------------------DPEKRPTA-EALQDEWDIKCHPWF
Kinase 29763.AA Dicty2 215-446 42 3.6e-74 252.72 In-house 1-244 (264) Show / Hide 
Range on Protein: 215-446
Range on HMM: 1-244/264
Sequence Identity: 42% (104 aa)

WQSG-EVLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYNQKDRQEKIQQIQSEIEALRNFSDKNIVRYIGIKKSETSINIFLEYVPGGSISSLLYRYGKF
 | | |..| | ||.|  | .| ||.| | ||. |     |   | .| |  ||. |.. .  |||.||.  ..|  ..|.|||. .|| |  . ..|.|
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCF

NETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGN---CKLADFGSAKKIV-EEKGHNDSIRGTPYWMAPETIKQLGSG----------SIGCT
 |.|.  . .|.||||.|||   .||||||.|| |. |.|     ||||||.| .|   .    ... ||||||||| |    ||          | |||
PESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVVGTPYWMAPEVIQM--SGNHCCTACDIWSLGCT

VIEMATAKPPWADKSPIQAMFYIANAQQPPPIPEHLSPVCKDFISKC
.||. |  ||  |  |  ||| . . .  ||.|.  || ||||   |
IIELLTGNPPYWDLNPMHAMFRMVQDDH-PPLPNDISPECKDFLMQC
Kinase 29763.AA MEKK2 215-448 44 9.6e-74 251.31 In-house 1-244 (262) Show / Hide 
Range on Protein: 215-448
Range on HMM: 1-244/262
Sequence Identity: 44% (109 aa)

WQSGEVLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYNQKDRQEKIQQIQSEIEALRNFSDKNIVRYIGIKKSET--SINIFLEYVPGGSISSLLYRYGK
|. | .|| | ||.| .   .|||  .||||| .   |   |.| .| .. ||. |.|   . || | |  . .    . ||.||.||||.   |  || 
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKE-VQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGA

FNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGNCKLADFGSAKK---IVEEKGHNDSIRGTPYWMAPETIKQLGSG------SIGCTVIEM
  ||  ||.| ||| |..||| | |.||||||||.| |  || ||.||| .|.   |  .     |. ||||||.|| |   | |      ||||||.||
LTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKADVWSIGCTVVEM

ATAKPPWADKSPIQAMFYIANAQQPPPIPEHLSPVCKDFISKCLK
 | |||||.   . |.| ||  .  | .|.|.|   .||. .| .
LTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFV
Kinase 29763.AA Pkinase 215-449 28 1.1e-69 242.68 Pfam 1-276 (293) Show / Hide 
Range on Protein: 215-449
Range on HMM: 1-276/293
Sequence Identity: 28% (80 aa)

WQSGEVLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYNQKDRQEKIQQIQSEIEALRNFSDKNIVRYIGIKKSETSINIFLEYVPGG----SISSLLY--
.. |...| ||||.| ......||.  |||..   . . . .|...    |||. ..... .||||....  ....| . .||..||    . ....   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

RYGKF--NETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGNC----KLADFGSAKKI-VEEKGHNDSIRGTPYWMAPETIK-QLGSG------
|.|.|   |  ....  |||.||||.|.. |||||.| .|.|.|..|..    |..|||.||..    .. .... |||..|||| |. . . |      
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SIGCTVIEMATAKPPWADK------SPIQAMFYIANAQQPPPIPEHLS-------------------PVCKDFISKCLKY
|.||...||.. .||. ..      ...| .. |  .. . ..|.  |                   . |||||..||..
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK
Kinase 29763.AA STE20 215-449 33 1.4e-66 227.46 In-house 1-271 (288) Show / Hide 
Range on Protein: 215-449
Range on HMM: 1-271/288
Sequence Identity: 33% (92 aa)

WQSGEVLGTGSFGQVILGMNIDTGEF----MAVKQVHIGGYNQKDRQEKIQQIQSEIEALRNFSDKNIVRYIGIKKSE----TSINIFLEYVPGGSISSL
..  |..| ||.|.| .. ...|||      |.|.. .   . .   .... || ||  ....  .|||.|.|    .    ... |  ||  |||.. .
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ--DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDI

LY---RYGK------FNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGNCKLADFGSAKKIVE-----EKGHNDSIRGTPYWMAPETIKQ--
.    . ||      .||  |   ....|.||.|||.. |||||||..|.|...||..|||||| . .. .     ...  ... ||||||||| |..  
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

---LGSG------SIGCTVIEMATAKPPWADKSPIQAMFYIANAQQPPP---I--PEHLSPVCKDFISKCLKY
    | .      | | | ||||. .|| .| .| .|||.|.. | |||      |.. ||  .||..||| .
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQK
Kinase 29763.AA ASK 220-448 38 3.2e-56 185.41 In-house 1-236 (254) Show / Hide 
Range on Protein: 220-448
Range on HMM: 1-236/254
Sequence Identity: 38% (92 aa)

VLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYNQKDRQEKIQQIQSEIEALRNFSDKNIVRYIGIKKSETSINIFLEYVPGGSISSLLY-RYGKFN--ET
||| |..| |  | . .|   .|.| .     .      . | .. ||.  ..   .|||.|.|   ..  . ||.| |||||.|.||  ..| ..  | 
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSR------YVQPLHEEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNEN

LIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDK-DGNCKLADFGSAKKIVEEKGHNDSIRGTPYWMAPETIKQLGSG--------SIGCTVIEMATAK
 .. .|.|||.||.||| ..|.|||||| ||||    | .|..||| .|..       .. .||  .|||| | |   |        |.|||..||||.|
TMNFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTETFTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTMVEMATGK

PPWAD-KSPIQAMFYIANAQQPPPIPEHLSPVCKDFISKCLK
||. . ..|  ||| .   .. |.||| ||  ||.|| .| .
PPFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFE
Kinase 29763.AA ULK 215-450 25 8.2e-56 191.73 In-house 1-308 (324) Show / Hide 
Range on Protein: 215-450
Range on HMM: 1-308/324
Sequence Identity: 25% (80 aa)

WQSGEVLGTGSFG-QVILGMNIDT---GEFMAVKQVHIGGYNQKDRQEK----IQQIQSEIEALRNFS---DKN--IVRYIGIKKSETS--INIFLEYVP
..  ..|| |||| .|  | |..|   ... |.|.. . . |.|  .      .|....||. .. .     .|  ||... .... ..  | |..|| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSISSLLYRYGK---------FNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGN------------CKLADFGSAKKIV---EEKGHNDS
||  .... ...|         ..|  ...| .||. |. .|| | ||||||| .| |. ..              .|.|||| ||..    .|.  . .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IR------GTPYWMAPETIK------QLGSG-----SIGCTVIEMATAKPP---WADKSPI------------QAMFYIANAQQPPPIPE---HLSPVCK
.       |||. |||. ..      . ..      |.||   || . |.|   |   . .            | ..|| | . ..|.|.   ..|| ||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQ-QIYIKNQPIQFPKPPKDPKISPECK

DFISKCLKYQ
|.|...|.|.
DLIRRMLQYD
Kinase 29763.AA ULK 215-450 26 7.3e-54 185.27 In-house 1-313 (329) Show / Hide 
Range on Protein: 215-450
Range on HMM: 1-313/329
Sequence Identity: 26% (82 aa)

WQSGEVLGTGSFGQVILGMNIDT----GEFMAVKQVHIGGYNQKDRQEK----IQQIQSEIEALRNFS----DKN----IVRYIGIKKSETS--INIFLE
..  ..|| ||||.|  | |..|    .|  |.|.. .   |||  .      .|....||. ..        ||    ||... .... ..  | |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YVPGGSISSLLYRYGK----------FNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKD------------GNCKLADFGSAKKIVEE-----
| .||  .... ...|          ..|  ...| .||| |. .|| | ||||||| .|.|....            | .|.|||| ||.. ..     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

KGHNDS----IRGTPYWMAPETIK------QLGSG-----SIGCTVIEMATAKPP--WADKSPIQAMFYIANAQQPPPIP----------------EHLS
  .  .    ..|||. |||. ..      . ..      |.||   || . |||  .  ... . .... . ..|||.|                 ..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PVCKDFISKCLKYQ
| |||.|...|.|.
PECKDLIRRMLQYD
Kinase 29763.AA Pkinase_Tyr 218-389 28 3.9e-18 62.06 Pfam 4-187 (270) Show / Hide 
Range on Protein: 218-389
Range on HMM: 4-187/270
Sequence Identity: 28% (53 aa)

GEVLGTGSFGQVILGMNI----DTGEFMAVKQVHIGGYNQKDRQEK--IQQIQSEIEALRNF-SDKNIVRYIGIKK-SETS--INIFLEYVPGGSISSLL
|..|| |.||.| .|       .|.   ||| .      ..  .|   ..   .|.. .... . .||||..|.    . .  | | .||.|.|.  . |
GKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

YRY----GKFNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGNCKLADFGSAKKI-VEEKG-HNDSIRGTPY-WMAPETIK
 .     ....   . .. .|| ||.|||... .||||.   |.||.... .| .||| |. |  ..   .  .    |  ||||| |.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECIN
Kinase 29763.AA TyrKc 215-456 21 3.1e-17 55.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 215-456
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

WQSGEVLGTGSFGQVILGMNIDTGEFMAVKQVHIGGYNQKDRQEKIQQIQSEIEALRNF--SDKNIVRYIGIKKSE-------TSINIFLEYVPGGSISS
 . |..|| | ||.| .|. .   .  ||| .. .          .. . .|.. ....  . .|||| .|.  ..         . | .||.|.|.  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

LLYRYGK-FNETLIRKFTQQILKGLEYLHAHEIIHRDIKGANVLVDKDGNCKLADFGSAKKIVEE------KGHNDSIR--GTP-----YWMAPETIKQL
 | .... ..     .|  || .| |||| . .||||.   |.||.... .| .||| ...| ..      |   ..    |.       |||||.| . 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NY

GSGSI-------GCTVIEMAT-AKPPWAD-----KSPIQAMFYIANAQQPPPIPE-------HLSPVCKDFISKCLKY--------QNQIELV
|  ..       | .  |. |  ..|. .     .|..... |. .   .|. |.       . ..   . ...| ..        .. .|. 
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 29763.AA STE11 456-488 33 7e-11 35.85 In-house 271-303 (303) Show / Hide 
Range on Protein: 456-488
Range on HMM: 271-303/303
Sequence Identity: 33% (11 aa)

VDLTKTQQILFLQFRINPNDRYNVRQLLNHPFI
... .....| . | ..|..|....|||.||||
WISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase 29763.AA STE 462-488 34 7e-07 20.47 In-house 331-359 (359) Show / Hide 
Range on Protein: 462-488
Range on HMM: 331-359/359
Sequence Identity: 34% (10 aa)

QQILFLQFRINPNDRYNVRQLLN--HPFI
.. . . ....||.| .. |||.  ||||
KDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 29763.AA STE20 471-488 50 0.000175 12.64 In-house 271-288 (288) Show / Hide 
Range on Protein: 471-488
Range on HMM: 271-288/288
Sequence Identity: 50% (9 aa)

INPNDRYNVRQLLNHPFI
..|..|  . |||.||||
KDPEKRPTASQLLKHPFI
Kinase 29763.AA Pkinase 472-488 35 0.001794 13.36 Pfam 277-293 (293) Show / Hide 
Range on Protein: 472-488
Range on HMM: 277-293/293
Sequence Identity: 35% (6 aa)

NPNDRYNVRQLLNHPFI
.|..|.. .|.|.||..
DPKKRPTAEQILQHPWF
Kinase 29763.AA ASK 460-488 24 0.011531 4.47 In-house 226-254 (254) Show / Hide 
Range on Protein: 460-488
Range on HMM: 226-254/254
Sequence Identity: 24% (7 aa)

KTQQILFLQFRINPNDRYNVRQLLNHPFI
.... .   | ..|..|   ..||. ||.
ECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase 29763.AA ULK 471-488 33 0.013466 4.99 In-house 312-329 (329) Show / Hide 
Range on Protein: 471-488
Range on HMM: 312-329/329
Sequence Identity: 33% (6 aa)

INPNDRYNVRQLLNHPFI
....|| .  .|.|||..
YDEKDRISWEELFNHPWF
Kinase 29763.AA Dicty2 473-488 56 0.015149 4.88 In-house 249-264 (264) Show / Hide 
Range on Protein: 473-488
Range on HMM: 249-264/264
Sequence Identity: 56% (9 aa)

PNDRYNVRQLLNHPFI
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PNQRMTAKQLLHHPWI
Kinase 29763.AA ULK 471-488 27 0.016626 4.78 In-house 307-324 (324) Show / Hide 
Range on Protein: 471-488
Range on HMM: 307-324/324
Sequence Identity: 27% (5 aa)

INPNDRYNVRQLLNHPFI
....|| .  ...|||..
YDEKDRISWEEIFNHPWF
Kinase 29763.AA MEKK15 474-488 53 0.254846 0.59 In-house 250-264 (264) Show / Hide 
Range on Protein: 474-488
Range on HMM: 250-264/264
Sequence Identity: 53% (8 aa)

NDRYNVRQLLNHPFI
..|    ||| ||||
HERPTASQLLKHPFI
Kinase 29763.AA Pkinase_Tyr 397-434 25 6.818059 0.26 Pfam 201-240 (270) Show / Hide 
Range on Protein: 397-434
Range on HMM: 201-240/270
Sequence Identity: 25% (10 aa)

GCTVIEMAT-AKPP-WADKSPIQAMFYIANAQQPPPIPEH
| .  |. |  . | ... |. . . ||.   .  |.||.
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN