Gene 3833 (Tetrahymena)

3833

Species: Tetrahymena
Alias: TTHERM_00444650, 51.m00199, 3833, PreTt03833, 477, 3704.m00055
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
3833.AA Protein None 1757 None Fasta, JSON
3833.kin_dom Protein Kinase Domain None 267 None Fasta, JSON
3833.NA RNA None 5274 None Fasta, JSON

Protein domain

Protein domains of 3833.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3833.AA ULK 27-293 32 1.4e-113 383.61 In-house 1-329 (329) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-329/329
Sequence Identity: 32% (107 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQTLKDEYVAIKHVEIQEGIKNTVN---NIELESVRQEIVTLQQLD--------HPNIVQLIDVKKNK--DNVYMV
|. | .|| | || ||||  .  . .  ..|.||.| ...|. ...  .   .. ......|| ....|.        |||||.|.|.....  .|.|..
YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYII

MEFCQHGDLEQFFNRKKESP----NPKKLTELEIRFYFSQIIEAFKYLRSKNLIHRDIKPQNILVKNDVWK-------------VADFGFAKKTTSN---
||.|..|||||. ...|..|    ..|.|.| |.. .| ||...||.|...| |||||||||||..|...|             .|||||||. ...   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

--ELTDFY------GTLATLAPQVMLQN-----YN-HKCDIYSLGATLYWILYNQFP---YKETNQK-----RLLEQ-------MEKNPVKCP---KEPH
   .. .       ||  . |||.  ..     |. .||||.|||  .|..||.. |   .  . |.     .|...       ..|.| ..|   ..|.
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

YSEELKNIVERMLIFDQNDRIDWEEIFQSKIF
 |.|.|..  |||..|..|||.|||.|. ..|
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 3833.AA ULK 27-293 33 1.1e-112 380.64 In-house 1-324 (324) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-324/324
Sequence Identity: 33% (109 aa)

YNENSKLGAGGFG-AVYKGLEVPLEGQTLKDEYVAIKHVEIQEGIKNTVN---NIELESVRQEIVTLQQLD---HPN--IVQLIDVKKNK--DNVYMVME
|. | .|| | ||  ||||  .  ..   ...|||.| ..... .|.  .   .. ... ..|| ....|.   |||  ||.|.|.....  .|.|..||
YCLNHCLGKGSFGVKVYKGRNKKTNT---QNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIME

FCQHGDLEQFFNRKKESP---NPKKLTELEIRFYFSQIIEAFKYLRSKNLIHRDIKPQNILVKNDVWK-------------VADFGFAKKTTSNELTDFY
.|..|||||. ...|..|   ..|.|.| |.. .| ||...||.|...| |||||||||||..|...|             .|||||||.  .|.. .. 
YCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQM

-----------GTLATLAPQVMLQN-----YN-HKCDIYSLGATLYWILYNQFP---YKETNQK----RLLEQ-------MEKNPVKCP---KEPHYSEE
           ||  . |||.  ..     |. .||||.|||  .|..||.. |   .  ..|.    .|...       ....|...|   |.|. |.|
CQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPE

LKNIVERMLIFDQNDRIDWEEIFQSKIF
.|..  |||..|..|||.|||||. ..|
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 3833.AA S_TKc 27-293 30 5.5e-74 253.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-231/231
Sequence Identity: 30% (85 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQTLKDEYVAIKHVEIQEGIKNTVNNIELESVRQEIVTLQQLDHPNIVQLIDVKKNKDNVYMVMEFCQH--GDLEQ
|    |.| |.|| |||. ..        ...|||| .               |..|.||  |.. .|||||.|.||  . |..|||||.| .  ||| .
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFD

FFNRKKESPNPKKLTELEIRFYFSQIIEAFKYLRSKNLIHRDIKPQNILVKNDVWKVADFGFAKKTTSNELTDFYGTLATLAPQVMLQNYNH-KCDIYSL
.  ...  .......| ..|||. ||..| .|. |.. ||||.||.|||. . . |..|||.|..      | | ||.  .|| |.   |.. |||..|.
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSC

GATLYWILYNQFPYKETNQKRLLEQMEKNPVKCPKEPHYSEELKNIVERMLIFDQNDRIDWEEIFQ-------SKIF
| .||  |. . |.   .........             |.|.|......| .| ..|.   |..|          |
GCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 3833.AA Ciliate-E2 27-293 25 5.1e-72 245.57 In-house 1-365 (365) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YNENSKLGAGGFGAVYKG--LEVP-------LEGQTLKDE----YVAIKHVEIQEGIKNTVNNIEL-ESVRQEIV----------TLQQLDHPNIVQLID
|. . |.| |.|| |||.   .|.        . | ...     .|.|| ...   .|| ...|.  ... .||            |.||.||||.....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VKK--NKDNVYMVMEFCQHGDLEQ-----FFNRKKESP-NPKKLTELEIRFYFSQIIE---------------AFKYLRSKN-LIHRDIKPQNILVKNDV
. .  ...|.|.|||.||.|||..       .|..| .   |..|| ||.... ||..               |..|| |||  |||||||.|||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

WKVADFGFAK-----------KTTSNELTDFY-----------------------GTLATLAPQVML-QN---------YNHKCDIYSLGATLYWILYNQ
 |..|||..|           |  ......                         ||.  .||..   ..         |..||||.||| .||. |...
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPYKETNQKRLLEQMEKNPVKCP----------------KEPHYSEELKNIVER----MLIFDQNDRID-WEEIFQSKIF
.|.        ..| ...... |                .  . |.| |..  .    ||  |.. ||. ||.|.. ..|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 3833.AA Ciliate-E2-Unclassified 27-293 26 4e-64 219.36 In-house 1-352 (352) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQTLKDEYV-----AIKHVEIQEGIKNTVNNIELESVRQEIV--------------TLQQLDHPNIVQLIDVKKNK
|. . ..| |||| |||        |  |. ..     ..|. ..   .......| .|  . ..                |....||.|| .......|
YKIIKQIGQGGFGKVYKC-------QHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDK

DNVYMVMEFCQHGDLEQFFNRKKES-----------PNPKKLTELEIR-----FYFSQIIEAFKYLRSKN-LIHRDIKPQNILVKND----VWKVADFGF
.|.|.|||.|..|||.|. . .| .            . |..|| ...     ||| ||.....|| .||  |||||||.|||..|.      |..|||.
QNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGI

AK-----------------KTTSNELTDFYGTLATL----APQVMLQ-NYN----HKCDIYSLGATLYWILYNQFPYKETNQKR----------------
.|                  . ......| ||. ..    || |. . ||.    .||||.|||  ||..|....|.. .|..                 
SKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQ

LLEQMEKNPVKCPKEP------HYSEELKNIVE----RMLIFDQNDRIDWEEIFQSKIF
|...  ..... ||.|      | |.| |....    .||  ..| ||..|.|..  .|
LYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 3833.AA Pkinase 27-293 28 5.5e-63 220.35 Pfam 1-293 (293) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-293/293
Sequence Identity: 28% (89 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQTLKDEYVAIKHVEIQEGIKNT-VNNIELESVRQEIVTLQQLDHPNIVQLIDVKKNKDNVYMVMEFCQHG----D
|   .|.|.|.|| |||. ..  .        ||.| .. ..  ..  .... |    .||  .. |.|||||.|.|.  .||..|||||.|..|    |
YHIGRKIGSGSFGCVYKCHHKGTGK------IVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMD

LEQFFNRKKESPNPKKL--TELEIRFYFSQIIEAFKYLRSKNLIHRDIKPQNILVK-NDVW----KVADFGFAKK--TTSNELTDFYGTLATLAPQVML-
|  .  .     . ...  .| |..||. ||... .|. |.. ||||.||.|||.. |..     |..|||.||.  . .|..|.| ||.  .|| | . 
LFDYIST----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRG

-QNYNHKCDIYSLGATLYWILYNQFPYKET------NQKRLLEQMEKNPVKCPKEPHYS-------------------EELKNIVERMLIFDQNDRIDWE
 | | .|.|..|.| .||  |  ..|...       .|. ....  . |.. . .  .|                   ||.| .....| .| ..|. .|
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

EIFQSKIF
.|.|.. |
QILQHPWF
Kinase 3833.AA CAMK 32-293 21 5.7e-63 201.46 In-house 1-425 (425) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-425/425
Sequence Identity: 21% (90 aa)

KLGAGGFGAVYKGLEVPLEGQTLK------DEYVAIKHVEIQEGIKNT---------VNNI------------ELESVRQEIVTLQQ-------LDHPNI
.|| |.|| |... .    |..         . |||| .. .   ...         ....             ...||.||  ...       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLIDVKKN-------------------KDNVYMVM---EFCQHGDL-EQFFNRKKESPNP------------KKLTELEIRFYFSQIIEAFKYLRSKNL
..|..|  .                   ....||||   |.|. |.| .  |.. .| ...            ...|| | |.|| ||..| .|. |.| 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPQNILVKND------------------VWKVADFGFAKKTTSNE-------------------------LTDFYGTLATLA-PQVMLQN-----
.|||.|| |||. ..                    |..|||||.| ...|                         ...| ||..  | | | ...     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YNHKCDIYSLGATLYWILYNQFPYKET-------------NQKRLLEQMEKNPVKCPKEP----------------------HYSEELKN
          |. |||. |.|  ||  |   .|. .              |...|.|.  |     | ..                      . |.| |.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IVERMLIFDQNDRIDWEEIFQSKIF
 . .||  | ..|.  |.. . . .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 3833.AA Ciliate-E2c 27-293 30 2.1e-61 210.28 In-house 1-310 (310) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-310/310
Sequence Identity: 30% (96 aa)

YNENSKLGAGGFGAVYKGLEVP-LEGQTLK---DEYVAIKHVEIQE-GIKNTVNNIELESVRQEIVTLQQLDHPNIVQLIDVKKNKDNVYMVMEFCQHGD
...|. || |..| |||.  .    .. ..       |||    ..  |.     . .||...||  . ...||.|.. .| |. . ..| .||.|  |.
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT

LEQFFNRKKESPNPK-KLTELEIRFYFSQIIEAFKYLRSK-NLIHRDIKPQNILVKNDVWKVADFGFAKKTTSNELTDFY------GTLATLAPQVMLQ-
|||.          | |..| .. .|||||| ||||| .. | .|||||| ||| .|.. | |||||.|. .  . .  .      ||    |||.    
LEQYIYH-------KPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGK

NYNH-KCDIYSLGATLYWILYNQFPYK-----------------ETNQKRLLEQMEKN----------------PVKCPKE--PHYSEELKNIVERMLIF
||.  | || ||| |||  |.  .| .                  .|    |.| ...                ... |..     |.|.| . ..|| .
NYYTEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQV

DQNDRIDWEEIFQSKIF
| ..||||.|||   ..
DEEKRIDWDEIFNHECI
Kinase 3833.AA AGC 27-293 20 3.5e-61 155.93 In-house 1-395 (395) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-395/395
Sequence Identity: 20% (83 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQTLKD--EYVAIKHVEIQE---GIKN-TVNNIELES-------VRQEIVTLQQLD----------HPNIVQ-LID
..    .| |.|| ||   ..  .    ||  .| |.| .. ..    .|  .| ..  |.       |..|   |....          ||.||. |  
FEFLKVIGKGSFGKVYLVRKKDGCH--KKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHY

VKKNKDN--VYMVMEFCQ--------HGDLEQFFNRKKESPNPK---KLTELEIRFYFSQ-------IIEAFKYLRS-KNLIHRD-IKPQNILVKNDVW-
  ..||.  .|.|||...         |..| |.  ..     .   ...| ..|||...       |. |. || | .. |||| .|| |||  .|   
SFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGR----RKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHI

KVADFGFAKKTTSNE----------------------------------------------------LTDFYG--TLATLAPQVMLQNYNHKCDIYS--L
| .|||..|.  ...                                                     . | |  |   .|| .    |.. ||..|  |
KLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---YGKACDWWSFGL

GATLYWILYNQFPYKETN----------QKRLLEQME------KNPVKCP--------KEPHYSEELKNIVERMLIFDQNDRID----------WEEIFQ
|. .|  |. . |.   |          .. . .. .      ...|| |        .... |.|.|......|  | ..|.            ||| .
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

SKIF
 . |
HPWF
Kinase 3833.AA STE 28-293 21 3.2e-54 186.45 In-house 1-359 (359) Show / Hide 
Range on Protein: 28-293
Range on HMM: 1-359/359
Sequence Identity: 21% (80 aa)

NEN-SKLGAGGFGAVYKGLEV-PL---EGQTL-----KDEYVAIKHVEIQEGIK----------NTVNNIELESVRQEIVTLQQLD--HPNIVQLIDVKK
 |. .|.| |.|| |||.. . .    . . .     . |..||| .....  .          ...|. |.... .|| ......  |||||. ..   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NK-------DNVYMVMEFCQHGDLEQFFNRKKESPNP--------KKLTELEIRFYFSQIIEA-FKYLRSKNLIHRDIKPQNILVKNDVWKVADFGFAKK
..       |.....||..  | |... ..|.. ..|        ... | .|...  ||...  .|| |.. |||||||.|||.     | .|||....
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

TTSN------------------ELTDFYGTLATLAPQVMLQN-------YNHKCDIYSLGATLYWILYNQFPYKETNQKRLLEQMEKNP-----------
 |..                  . . | ||    || |..||       |. ||||.||| |.   .  . |. . .  | . .. .|            
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCI

--VKCPKEP--------------------HYSEELKNIVERMLIFDQNDRIDWEEIFQ--SKIF
   ..|. |                    ..|.|.|. ... |. | |.| . ..  .   . .
VNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 3833.AA CAMKL 27-293 24 3.1e-52 164.92 In-house 1-297 (297) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-297/297
Sequence Identity: 24% (77 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQT-LK-DEYVAIKHVEIQEGIKNTVNNI---------ELESVRQEIVTLQQLD---HPNIVQLIDVKKNKDN---
|.    || |.|| |         ..  .   | |||| ....   ......           .  .|.||  ...|.   ||||..| .|  ....   
YRIGKTLGKGSFGKVK-------LATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIE

---VYMVMEFCQHGD------LEQFFNRKKESPNPKKLTELEIRFYFSQIIEAFKYLRSKNLIHRDIKPQNILVK-ND--VWKVADFGFAKKTTS-----
   .|.||| |. |.      ...  .|.      ....| | |.|| ||..| .|. |.. .|||||| |||.  |.  . |..||||. . .      
TKKIYLVMEYCSGGEMDLFDYIVKHGHRR------GRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGP

NE-LTDFYGTLATLAPQVMLQ--N-YN-HKCDIYSLGATLYWILYNQFPYKET--------NQKRLLEQMEKNPVKCPKEPHYSEELKNIVERMLIFDQN
.. |. | |...  || . .     |.  | || |.| .|| ... ..| ..         |. .|...  .   . |. .| | .....  .||  . .
GQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPE

DRIDWEEIFQSKIF
.|.  ..| . . .
KRPTIHQIMNHPWM
Kinase 3833.AA Ciliate-E2b 27-243 27 1.1e-46 139.98 In-house 1-216 (272) Show / Hide 
Range on Protein: 27-243
Range on HMM: 1-216/272
Sequence Identity: 27% (64 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQTLKDEYVAIKHVEIQEGIKNTVNNIELESVRQEIVTLQQLDHPNIVQLIDVKKNKDNVYMVMEFCQHGDLEQFF
  .  ||| | || || . .        ...| |.| ... . |.   .|.|. .  ||. .|. ..||.|...|. .| ....|..||||. ..|.   
MIYIKKLGFGQFGSVYLVWNT-----KNTKQYYAMKCISKNQIIQ---QNMEK-HMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVI

NRKKESPNPK--KLTELEIRFYFSQIIEAFKYLRSKNLIHRDIKPQNILVKNDVW-KVADFGFAKKTTSNEL-----TDFYGTLATLAPQVML------Q
       . .   | . . .||. .|. ...|| ..| |.||||| ||.| .. . | .|.| ||   ...      .   ||.  .||...       .
R------EIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGK

NYNHKCDIYSLGATLYWILYNQFPYKETNQK
 |. | ||.|.| .|| ..  . |. |  |.
GYTYKVDIWSVGICLYEFMCGYVPWAEDVQD
Kinase 3833.AA Pkinase_Tyr 27-185 32 6.3e-22 74.89 Pfam 1-156 (270) Show / Hide 
Range on Protein: 27-185
Range on HMM: 1-156/270
Sequence Identity: 32% (54 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQTLKDEYVAIKHVEIQEGIKNTVNNIE--LESVRQEIVTLQQL-DHPNIVQLIDVKK-NKDN--VYMVMEFCQHG
   . |||.| || ||||   .   .  ..  ||.| .       ..    .  .|.  .|. .. || .|||||.|. |    ..   .|.|||...||
ITFGKKLGEGAFGEVYKGTWKG--DPDNTKIPVAVKMLK------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG

DLEQFFNRKKESPNPKKLTELEIRFYFSQIIEAFKYLRSKNLIHRDIKPQNILVK-NDVWKVADFG
||  .  ...  .....||  ..  .  || ..  || |||.||||.   |.||. | | |..|||
DLLDYLRKHR--EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 3833.AA TyrKc 27-293 23 1.3e-16 45.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-280/280
Sequence Identity: 23% (73 aa)

YNENSKLGAGGFGAVYKGLEVPLEGQTLKDEYVAIKHVEIQEGIKNTVNNIELESVRQEIVTLQQL--DHPNIVQLIDVKKNK-------DNVYMVMEFC
   . ||| | || ||||            . ||.| .              .|  ..|.  . .|  .|||||.|. |   .       . ...|||..
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYM

QHGDLEQFFNRKKESPNPKKLTELEIRFYFSQIIEAFKYLRSKNLIHRDIKPQNILVKNDV-WKVADFGFAKKTTSN----ELTDFYGT----LAT----
 |||| ..  ....      |.  .   .  || .   || |||.||||.   |.||...   |..||| ... ..     | .| | .     .     
PHGDLKDYLRKHRPK-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

---LAPQVMLQN-YNHKCDIYSLGATLYWIL-YNQFPYKE-----TNQKRLLEQMEKN-PVKCPKE------PHYSEELKNIVERMLIFDQNDRIDWEEI
   .|| ..  . ...| |..| | ... |. | | || .      . ....|. ..    ..|..      .. ..|. .| ..   .| .||   .||
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

FQSKIF
   ..|
--HECF
CNMP_binding 3833.AA cNMP_binding 1263-1361 15 2.5e-08 31.21 Pfam 19-91 (91) Show / Hide 
Range on Protein: 1263-1361
Range on HMM: 19-91/91
Sequence Identity: 15% (15 aa)

SIYFVLKGQFILKQCLNYDENQCNKTEEEQQIQEKPLKNKIPSKNVYKDIKYIKKGQFFGMFEFLTGQ-KRLYIAESQNVSIVIRLPLNKFLDIIKSDEK
..|.||.|.. . .     . |                           . ....|.|||  ...|.| .| . ....  . ..|.| ..|....... .
HFYIVLSGKVKVYK-DEDGREQ--------------------------ILGFLGPGDFFGEMALFTNQNPRTATVVALTDCECWRIPREDFRQLMQQHPE
ZnF_C2HC 3833.AA ZnF_C2HC 1385-1401 35 0.000138 18.76 SMART 1-17 (17) Show / Hide 
Range on Protein: 1385-1401
Range on HMM: 1-17/17
Sequence Identity: 35% (6 aa)

PCYTCGQVDHFFINCSK
 || ||. .|.  .| .
KCYNCGKPGHWARDCPN