Gene 3104 (Tetrahymena)

3104

Species: Tetrahymena
Alias: 3718.m00008, 3104, PreTt03104, 382, TTHERM_00535190, 69.m00146
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
3104.NA RNA None 1581 None Fasta, JSON
3104.AA Protein None 526 None Fasta, JSON
3104.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 3104.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3104.AA ULK 9-263 32 3.8e-124 418.73 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-329/329
Sequence Identity: 32% (108 aa)

YTLHEALGSGQYGKVYKALNVRT----NSLVAIKAVKVEKFKEVPKLEE------FTMNEIQTLARIN--------NPYIVKFIEMLKTK--NHYYFVYE
| |.. ||.|..|||||. |..|    | .||.| .  .|... ... |      . .|||... ...        .|.|||......|.  |..|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCNGGTLEDIIN----------NQKTLPEHEALKIFKQLVAAFTSIVKNNIMHRDLKPANILLHNGQ-------------VKLADFGFCKALQSP---QD
|||||.||..|.          ..|.|.| ||...|||....|  ..|.||.|||.||.|||.||||             .|.|||||.| ....   |.
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LSQTMV------GSPIYMAPEILTGH----DYT-MKADIWSLGCVLYEMLYGECPYEESTIAKLI-----SAVEG----------RDIQYP---SKYNVS
. .|.|      |.|.||||.|| |.    .|.  |.|||||||..||||||..|.... . ...     . ..           . .|.|   .....|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

QKTITLLKDILIKDATKRIDWDELFKRELT
.... |..  |..| ..||.|.|||. .. 
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 3104.AA ULK 9-263 34 7.69999999999e-124 417.72 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-324/324
Sequence Identity: 34% (113 aa)

YTLHEALGSGQYG-KVYKALNVRT---NSLVAIKAVKVEKFKEVPKL------EEFTMNEIQTLARIN---NPY--IVKFIEMLKTK--NHYYFVYEYCN
| |.. ||.|..| ||||. |..|   | .||.| .   |... ...       .. .||||..  ..   .|.  |||......|.  |..|...||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGTLEDIIN---------NQKTLPEHEALKIFKQLVAAFTSIVKNNIMHRDLKPANILLHNGQ-------------VKLADFGFCKALQSP---QDLSQT
||.||..|.         ..|.|.| ||...|||....|  ..|.||.|||.||.|||.||||             .|.|||||.| ....   |.. ||
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

MV------GSPIYMAPEILTGH----DYT-MKADIWSLGCVLYEMLYGECP----YEEST--IAKLISA-------VEGRDIQYP---SKYNVSQKTITL
.|      |.|.||||.|| |.    .|.  |.|||||||..||||||..|    ...    |.|||         .. . ||.|   . ...|.... |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

LKDILIKDATKRIDWDELFKRELT
..  |..| ..||.|.|.|. .. 
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 3104.AA Ciliate-E2c 9-263 36 3.1e-88 299.42 In-house 1-310 (310) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-310/310
Sequence Identity: 36% (112 aa)

YTLHEALGSGQYGKVYKA----------LNVRTNSLVAIKAVKVEKF----KEVPKLEEFTMNEIQTLARINNPYIVKFIEMLKTKNHYYFVYEYCNGGT
.   . ||||.|||||||          .||. | | |||      .        . .|. ..||. .   |.|.|.||..  .|..| |.. |||||||
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT

LEDIINNQKTLPEHEALKIFKQLVAAFTSIVKN-NIMHRDLKPANILLHNGQVKLADFGFCKALQSPQDL-SQ---TMVGSPIYMAPEILTG-HDYTMKA
||. | .   . | . |  |.|...||  . |. || |||.||.|||.|||..|.||||| |  |   .   |   | .|.|.||||.|| |   || |.
LEQYIYHKPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYYTEKS

DIWSLGCVLYEMLYGECPYE------------------ESTIAKLISAVE---------------GRDIQYPSK--YNVSQKTITLLKDILIKDATKRID
||||||..||.||. . | |                  ..| ..|. ...                . |. |     |.||..  |..  | .|  ||||
DIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEKRID

WDELFKRELT
|||.|  |. 
WDEIFNHECI
Kinase 3104.AA S_TKc 9-263 31 3.8e-87 296.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YTLHEALGSGQYGKVYKALNVRTNSLVAIKAVKVEKFKEVPKLEEFTMNEIQTLARINNPYIVKFIEMLKTKNHYYFVYEYCNG--GTLEDIINNQKT--
|.... .|.| .|||||. ...|. .|||| .|           | ...||| | . . |.|||....  . .|.|.| |||.|  |.| |.| ....  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPEHEALKIFKQLVAAFTSIVKNNIMHRDLKPANILLHNGQVKLADFGFCKALQSPQDLSQTMVGSPIYMAPEILTGHDYTM-KADIWSLGCVLYE
    .|| .| ....|.. |   . ...|.||||||.|||| . ..|..|||... |        |..|.| |||||.|    |.  |.|.||.||.|||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLYGECPYEESTIAKLISAVEGRDIQYPSKYNVSQKTITLLKDILIKDATKRIDWDELFK-------RELT
||.|. |..  ......  .             |.  . ... .| || .||.   |...        .  
MLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 3104.AA Ciliate-E2 9-263 24 6.7e-82 278.4 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YTLHEALGSGQYGKVYKALNVRTNSLVAIK---------------AVKVEKFKEV-PKLEEFTMNEIQTL----------------ARINNPYIVKFIEM
| ... .|.|..|.|||. . ... ..|||               ..|    | . ..  |....||. .                 ..|.|.|.|..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LK--TKNHYYFVYEYCNGGTLEDIINNQKTLP-----------EHEALKIFKQLVA---------------AFTSIVKNN-IMHRDLKPANILLHNGQVK
 .  ..|..|.| |||.||.|.|.|.|.|.             | |...|.||..                |. .. ..| |.|||.|| |||.    .|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

LADFGFCKALQSP-------------------------------QDLSQTMVGSPIYMAPEILT---------GHDYTMKADIWSLGCVLYEMLYGECPY
..|||..| .. .                               |.. .| .|.| |||||||          ...|. |.||||||..|||||.|. |.
IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF

EESTIAKLISAVEGRDIQYP----------------SKYNVSQKTITLLKD----ILIKDATKRID-WDELFKRELT
        .   .  .|..|                |. ..||... |.|     .| ||  |||. |..... .  
--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 3104.AA Ciliate-E2-Unclassified 9-259 24 1.6e-79 270.49 In-house 1-348 (352) Show / Hide 
Range on Protein: 9-259
Range on HMM: 1-348/352
Sequence Identity: 24% (87 aa)

YTLHEALGSGQYGKVYKALNVRTNSLV---------AIKAVKVEKFKEVPKLEEFTMNEIQ-------------TLARINNPYIVKFIEMLKTKNHYYFV
|.... .|.|..|||||. .  .. ..          |...|  ..|.  ..|. .||...              |  ...|.|||.... ..|.. |.|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

YEYCNGGTLEDIINNQKT-----------------LPEHEAL-----KIFKQLVAAFTSIVKNN-IMHRDLKPANILLHNG----QVKLADFGFCKALQS
.|||.||.|...|...|.                 ..| .|.     ..|.|.. .. .. ..| | |||.|| |||..|.    ..|..|||..| .|.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

P---------------QDLSQTMVGSPIYM----APEILTGHDYT----MKADIWSLGCVLYEMLYGECPYEESTIAK----------------LISAVE
.               |....|..|.|.||    |||.| |. |      |.||||||..|||||.|..|..  .  .                |..   
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

GRDIQYPS--K----YNVSQKTITLLK----DILIKDATKRIDWDELFK
 ..||.|.  .    ...|.. . ...     .| |.  |||.......
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 3104.AA Pkinase 9-263 29 3.4e-75 260.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

YTLHEALGSGQYGKVYKALNVRTNSLVAIKAVKVEKFKE-VPKLEEFTMNEIQTLARINNPYIVKFIEMLKTKNHYYFVYEYCNGG----TLEDIIN--N
|.... .||| .|.|||. .. |. .||.| .|... |. ...    . .||| ..|.| |.||.....  .|.|.|.| |||.||     | |.|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

QKTL--PEHEALKIFKQLVAAFTSIVKNNIMHRDLKPANILLH-NGQV----KLADFGFCKAL-QSPQDLSQTMVGSPIYMAPEILT-GHDYTMKADIWS
....  .|.|. ....|.. .   . ...|.||||||.|||.. ||..    |..|||..| .   ..   .| .|.| |||||..  | .|. |.|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGCVLYEMLYGECPYEES------TIAKLISAVEGRDIQYPSK-------------------YNVSQKTITLLKDILIKDATKRIDWDELFKRELT
.||.||||| |. |. ..      .  ..|  . |... ...                    .|.|.  . ..|..| || .||. ...... .  
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 3104.AA CAMK 14-252 21 4.5e-75 241.15 In-house 1-414 (425) Show / Hide 
Range on Protein: 14-252
Range on HMM: 1-414/425
Sequence Identity: 21% (89 aa)

ALGSGQYGKVYKALNVRTN------------SLVAIKAVKVEKFKE------------------------VPKLEEFTMNEIQTLAR-------INNPYI
 ||.|..|||... . .|.              |||| .. .| |.                         || ... ..||. . .       .. | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFIEMLK------------TKNH--------YYFVY---EYCNGG----TLEDIINNQ---------------KTLPEHEALKIFKQLVAAFTSIVKNN
.|..|.              | ..        .|.|    ||| ||     | | |  .               . ..|.|| ..|.|.. |   . ..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDLKPANILL-HN-----------------GQVKLADFGFCKALQS-----------------------PQDLSQTMVGSPIYMA-PEILTG-----
|.|||||| |||| .|                 ...|..|||| . ...                       . .. .|..|.| ||| ||.| |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------HDYTMKADIWSLGCVLYEMLYGECPYEES-------------TIAKLISAVEGRDIQYPSKY----------------------NVSQKTI
           |. |.|.||.|..|| || |. |....             .. .|   .   . ..|..|                      .|||  .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

TLLKDILIKDATKRI
 |.. .| .| .||.
DLIRKMLQVDPEKRM
Kinase 3104.AA CAMKL 9-263 31 3.8e-70 223.0 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-297/297
Sequence Identity: 31% (95 aa)

YTLHEALGSGQYGKVYKALN-VRTNSLVAIKAVKVEKFKEVPKLEEF-----------TMNEIQTLARIN---NPYIVKFIEMLKTKNH------YYFVY
|.. . || | .|||  |..   |.  |||| .. .| .. |. .                ||| . ..|    | |.|. |.. |..|      .| | 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCNGGT--LEDIINNQ----KTLPEHEALKIFKQLVAAFTSIVKNNIMHRDLKPANILLH-NG--QVKLADFGFCKALQS----PQDLSQTMVGSPIYM
||| ||   | | | ..    . .||||| ..|.|.|.|   . ...| |||.|| ||||  ||  ..|..||||.   .     | ..  |  ||| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILTG-HD-YT-MKADIWSLGCVLYEMLYGECPYEESTIA-------KLISAVEGRDIQYPSKYNVSQKTITLLKDILIKDATKRIDWDELFKRELT
||||. | .. |   |.||||.| .|| |..|. | .. |..       .|   . .   ..|  | ||   . |.. .| .. .||.  ... . .  
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 3104.AA Ciliate-E2b 14-209 33 3.8e-69 209.28 In-house 6-212 (272) Show / Hide 
Range on Protein: 14-209
Range on HMM: 6-212/272
Sequence Identity: 33% (70 aa)

ALGSGQYGKVYKALN-VRTNSLVAIKAVKVEKFKEVPKLEEFTMNEIQTLARINNPYIVKFIEMLKTKNHYYFVYEYCNGGTLEDIINNQK--TLPEHEA
 ||.||.| ||   |   |. . |.|...  .  .   .|   ..|...| ..| |.|.|||   |...| ||. |.|||. |.|.| ...   | . ..
KLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQ-NMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLSTYDS

LKIFKQLVAAFTSIVKNNIMHRDLKPANILLHN-GQVKLADFGFCKALQSPQD---LSQTMVGSPIYMAPEILT-----GHDYTMKADIWSLGCVLYEML
. ...... ..    ..||..||.|| ||.... |..||.|.|  | ... ..      |..| | ||||||..     |  ||.|.||||.| .|||..
QFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFM

YGECPYEE
 |  |. |
CGYVPWAE
Kinase 3104.AA STE 9-263 23 5.7e-68 232.12 In-house 1-359 (359) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-359/359
Sequence Identity: 23% (84 aa)

YTLHEALGSGQYGKVYKALNV------RTNSL---------VAIKAVKVEKFK-EVPK-------------LEEFTMNEIQTLARIN--NPYIVKFIEML
... | .|.| .|.||||.|.      .|. .         .||| ...|. . .. .              ..  ..||... . |   |.|||.. . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

KTK-------NHYYFVYEYCNGGTLEDIINN----QKTLP----------EHEALKIFKQLVAA-FTSIVKNNIMHRDLKPANILLHNGQVKLADFGFCK
  .       .. . . ||..||.|.|||..    .|.|.          |..  .| .|.. .    . ...|.|||.|||||||    |||.|||.|.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCG

ALQS---------------PQD-LSQTMVGSPIYMAPEILTG------HDYTMKADIWSLGCVLYEMLYGECPYEESTIAKLISAVE-------------
 |..                ..  ..|.||.| .||||....      ..|. |.|||||||.. ||. |. |. . .  . . .               
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GRDIQYPS-----------------KYNVSQKTITLLKDILIKDATKRIDWDELFK--RELT
   |   . |.                 . ..|.. .  ..  |.||  || . ..| |   .  
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 3104.AA STE20 9-207 34 5.5e-60 205.6 In-house 1-227 (288) Show / Hide 
Range on Protein: 9-207
Range on HMM: 1-227/288
Sequence Identity: 34% (80 aa)

YTLHEALGSGQYGKVYKALNVRTNSL----VAIKAVKVEKF---KEVPKLEEFTMNEIQTLARINNPYIVKFIEMLKTK----NHYYFVYEYCNGGTLED
|.| | .|.| ||||||| ...|. .    |||| ...||    .   . .|  ..||. ... ..|.|||...    .    .. . | |||.||.| |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ---DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTD

IINN----QK-----TLPEHEALKIFKQLVAAFTSIVKNNIMHRDLKPANILL-HNGQVKLADFGFCKALQS----PQD-LSQTMVGSPIYMAPEILTG-
|...    .|     .. | .   | .... .   . .|.|.|||.| .|||| ..|.|||||||.|  |..     ..   .|.||.| .||||.. . 
IMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCM

----HDYTMKADIWSLGCVLYEMLYGECPY
    ..|. |.||||||  . ||. || ||
EGPDKGYDYKCDIWSLGITAIEMAEGEPPY
Kinase 3104.AA Pkinase_Tyr 9-209 27 2.6e-19 66.01 Pfam 1-218 (270) Show / Hide 
Range on Protein: 9-209
Range on HMM: 1-218/270
Sequence Identity: 27% (60 aa)

YTLHEALGSGQYGKVYKALNV----RTNSLVAIKAVKVEKFKE-VPKLEEFTMNEIQTLARI-NNPYIVKFIEMLK-TKNH--YYFVYEYCNGGTLEDII
 |. . ||.|..|.|||.        |.  ||.| .|    .|   ..|.|   |....  . ..| ||...      . .  .| | ||. .| | |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

NN----QKTLPEHEALKIFKQLVAAFTSIVKNNIMHRDLKPANILLH-NGQVKLADFGFCKAL-QSPQD-LSQTMVGSPI-YMAPEILTGHDYTMKADIW
 .    .. |. .. |..  |  ..      .|. ||||   |.|.. |..|| .||| ....    .   ...    ||  |||| .    .| | |.|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGCVLYEMLY-GECP-YEE
| | ...|..  || | |..
SFGVLMWEIFTYGEQPTYPG
Kinase 3104.AA TyrKc 9-262 21 2e-17 58.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YTLHEALGSGQYGKVYKALNVRTNSLVAIKAVKVEKFKEVPKLEEFTMNEIQTLARI--NNPYIVKFIEMLKTK-------NHYYFVYEYCNGGTLEDII
 || . ||.|..|.|||.        ||.| .| ..      .|.| |.|.. . ..  ..| ||...    ..         .. | ||. .| | | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

-NNQKTLPEHEALKIFKQLVAAFTSIVKNNIMHRDLKPANILLHNGQ-VKLADFGFCKALQSP-------QDLSQT---MVG--SPI-YMAPEILTGHDY
 .....|.  . |..  |  .    . ..|. ||||   |.|..... || .||| .... .        .  ...         ||  |||| .  . .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TMKADIWSLGCVLYEML-YGECPYEE-----STIAKLISAVEGRDIQYPSKYN-------VSQKTITLLKDILIKDATKRIDWDELFKREL
| | |.|| | ...|.. ||. ||..      . . .|  |. ..   . ...        ...  .. |.    |. .|    |. ....
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF