Gene 26742 (Tetrahymena)

26742

Species: Tetrahymena
Alias: 26742, PreTt26742, 3702.m00161, TTHERM_00145340, 490, 11.m00439
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
26742.AA Protein None 773 None Fasta, JSON
26742.kin_dom Protein Kinase Domain None 254 None Fasta, JSON
26742.NA RNA None 2322 None Fasta, JSON

Protein domain

Protein domains of 26742.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26742.AA ULK 88-341 34 7.1e-126 424.49 In-house 1-324 (324) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-324/324
Sequence Identity: 34% (113 aa)

YCLPDIIGKGYSS-KVYRGKNETT---GDTVAVKVIDMKGIKN-------EVQSFLLKNEISVLKKLN---NIN--CLKLFDVFHTA--NNTYIITEFCD
||| ...|||    |||.|.|. |   .  ||.|.||.|....       ... .||||||...|||.   . |  . ||.|.| |.  ||.|||.|.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

HGDLKELITKYGT---------FSEKPAVKILKHLLNGLDEMQNKGIIHRDLKLANILVKEGIPK-------------IADFGFSKDLN---AEPCKFYY
.|||...| |...         .||. |....|...||. |.....|||||.|..|||...|.||             ||||||.| ..    | .....
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

NV------GTPMYMCPQSLT----KNEYS-FKSDIWSIGVLFYEMIYNITP---WVADTEK----QLVDK-------MTSIPVSFP---ATPIVSEESKD
 |      |||.||.|| |     . .|. .|.||||.|..||||.|. .|   | . ...    .|...       .   |. ||   . |..|.|.||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

FIRGCLTIDESKRFSLKDMLDHPLL
.||..|..||..|.|  ....||..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 26742.AA ULK 88-341 33 1e-121 410.65 In-house 1-329 (329) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-329/329
Sequence Identity: 33% (112 aa)

YCLPDIIGKGYSSKVYRGKNETT----GDTVAVKVIDMKGIKN-------EVQSFLLKNEISVLKKLN----NIN----CLKLFDVFHTA--NNTYIITE
||| ...|||   |||.|.|. |    .  ||.|.|| . ...       ... .|||||| ..|||.    ..|    . ||.|.| |.  ||.|||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCDHGDLKELITKYGT----------FSEKPAVKILKHLLNGLDEMQNKGIIHRDLKLANILVKEGIPK-------------IADFGFSKDLNAE---PC
.|..|||...| |...          .||. |....|..|||. |.. ..|||||.|..|||...|.||             ||||||.| .. .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

KFYYNV------GTPMYMCPQSLT----KNEYS-FKSDIWSIGVLFYEMIYNITP---WVADTEK-----QLVDK-------MTSIPVSFP---ATPIVS
 ... |      |||.||.|| |     . .|. .|.||||.|..||||.|. .|   | . ...     .|...       . ..|  ||   . |..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

EESKDFIRGCLTIDESKRFSLKDMLDHPLL
.|.||.||..|..||..|.|  ....||..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 26742.AA S_TKc 88-341 33 2.1e-80 274.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

YCLPDIIGKGYSSKVYRGKNETTGDTVAVKVIDMKGIKNEVQSFLLKNEISVLKKLNNINCLKLFDVFHTANNTYIITEFCDH--GDLKELITKYGT---
| . ..||||  .|||....  ||  ||.|.|.            ...||..||| .  |  ||.|||.. .. |...|.||.  |||...| |.|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEKPAVKILKHLLNGLDEMQNKGIIHRDLKLANILVKEGIPKIADFGFSKDLNAEPCKFYYNVGTPMYMCPQSLTKNEYSF-KSDIWSIGVLFYEM
   |.|  | .... ....|. . ..|||||||| .|||. |   ||.|||... |       .  .||| || |  |    |.. |.|.||.|...|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

IYNITPWVADTEKQLVDKMTSIPVSFPATPIVSEESKDFIRGCLTIDESKRFSLKDMLD-------HPLL
..  .|.   ..... .|.             |.| |||||.||. | .|| .  . |        || .
LCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26742.AA CAMK 93-341 20 2.1e-75 242.27 In-house 1-425 (425) Show / Hide 
Range on Protein: 93-341
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

IIGKGYSSKVYRGKNE-TTGDT-----------VAVKVIDMKGIKN-------------------------EVQSFLLKNEISVLKK-------LNNINC
..|.|  .||.....  |||..           ||.|.|| | .|.                         ..    ...||...||       |.  | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKLFDVFH------------TANN--------TYIIT---EFCDHG----DLKELITKY---------------GTFSEKPAVKILKHLLNGLDEMQNKG
.||..|.             | ..         |...   |.|. |    || . |..                | |.|. | .. . .. ... . ...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKLANILVKE------------------GIPKIADFGFSKDLNA-----------------------EPCKFYYNVGTPMYMC-PQSLTK-----
|.|||||. |||. .                  .  ||.||||.. ..                        |  |..  .||| ||. |  | .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------NEYSFKSDIWSIGVLFYEMIYNITPWVAD-------------TEKQLVDKMTSIPVSFPATPI--------------VSEE--------SK
           |..|.|.||.||. | |     |. .|             ....|  | ..   .||  ..              .|.|         |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFIRGCLTIDESKRFSLKDMLDHPLL
|.||..|. | .||..... |.|| .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 26742.AA Pkinase 88-341 30 5.1e-69 240.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

YCLPDIIGKGYSSKVYRGKNETTGDTVAVKVIDMKGIKNEVQ--SFLLKNEISVLKKLNNINCLKLFDVFHTANNTYIITEFCDHG----DLKELIT--K
|..  .||.| ...||....  ||..||||.|. ...| ...   ..| .||...|.||  | ..|.|.|.. .. |...|.|..|    ||...|.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

YGTF--SEKPAVKILKHLLNGLDEMQNKGIIHRDLKLANILVK-EGIP----KIADFGFSKDL-NAEPCKFYYNVGTPMYMCPQSLT-KNEYSFKSDIWS
.|.|  ||. . .... .| ||. . ..||||||||..|||.. .| .    ||.|||..| . .     ..  .||| || |  .   ..|. |.|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGVLFYEMIYNITPWVAD------TEKQLVDKMTSIPVSFPATPIVS-------------------EESKDFIRGCLTIDESKRFSLKDMLDHPLL
.|...|||.   .|.  .      ...|....  . |..|.     |                   || ||||..||. | .|| . .. | || .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 26742.AA Ciliate-E2 88-341 23 1.2e-68 234.4 In-house 1-365 (365) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)

YCLPDIIGKGYSSKVYRGKNETTGD------------------TVAVKVIDMKGI-KNEVQSFLLKNEIS--------------VLKKLNNINCLKLFDV
| .  .||.|  ..||..|.  ..                    |..| . || . ||...... .. |               .|..||. | .|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FH--TANNTYIITEFCDHGDLKELIT------------KYGTFSEKPAVKILKHLLN---------------GLDEMQNKG-IIHRDLKLANILVKEGIP
|   . || |...|.|..|||...|             . . |.|| . .| |..|.               .| .. .|. |||||.|. |||.    .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----I

KIADFGFSKDLNAE-----------PCKFYYN---------------------VGTPMYMCPQSLTKNE---------YSFKSDIWSIGVLFYEMIYNIT
||.|||.||... .            ..|  |                     .|||.||.|. | . .         |..|.||||.||..|||... .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWVADTEKQLVDKMTSI---PVSFP----------------ATPIVSEESKDFIRG----CLTIDESKRFS-LKDMLDHPLL
|.           .  |   ...||                 .  .|.| ||.|.     .|  |..||..  .. |.|| .
PF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 26742.AA Ciliate-E2-Unclassified 88-341 22 4.9e-62 212.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-352/352
Sequence Identity: 22% (81 aa)

YCLPDIIGKGYSSKVYRGKNETTGDTV-----AVKVIDMK-GIKNEVQSFLLKNEISVLKK------------------LNNINCLKLFDVFHTANNTYI
| .  .||.|  .|||. ... ..  .     . |... |  ......  .. ... . .|                  ..... .|.|..| . .| ||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ITEFCDHGDLKELITKYGT-----------------FSEKPAV-----KILKHLLNGL-DEMQNKGIIHRDLKLANILVKEG----IPKIADFGFSKDLN
..|.|..|||.. |.|...                 |.|. |.     ......|.||    ....|||||.|. |||....     .||.|||.|| ..
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

AE---------------PCKFYYNVGTPMYM----CPQSLTKNEYS----FKSDIWSIGVLFYEMIYNITPWVADTEKQ----------------LVDKM
                 ..... ..|||.||     |  | ...|.    .|.|||| ||..|||...  |  . ...|                | .. 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

TSIPVSFPATP------IVSEESKDFIR----GCLTIDESKRFSLKDMLDHPLL
   ...||  |      ..|.| ||||.     .|  . .|| .... | ||..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 26742.AA CAMK-Unique 88-341 23 1.1e-58 192.24 In-house 1-363 (363) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-363/363
Sequence Identity: 23% (86 aa)

YCLPDIIGKGYSSKVYRGKNETTGDTVAVKVIDMKGIKNEVQSF-----------------LLKNEISVLKKLNNINCLKLFDV----FHTAN-------
| .  |||.|  ..||.... .||.  |.|..  .. .|..|                    ||.|....|...  | .||.|.    |....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NTYIITEFCDHGDLKELITK--------------------YGTFSE--KPAVKILKHLLNGLDEMQNKGIIHRDLKLANILVKEGIP-----
        . ||..|.|. |||...| |                     | |||    .  |   ||  .  | ...|.|||||| ||.|..  .     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

------------KIADFGFSKDLN-AEPCK-FYYNVGTPMYMCP--------------QSLTKNEYSFKS----DIWSIGVLFYEMIYNITPWVADTEK-
            |..||| ....|  . |      .|||.|| |              . .    |. ..    ||||.||. |.|.  ..|  ...|. 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------QLVDKMTSIPV-SFP--ATPI---VSEESKDFIRGCLTIDESKRFSLKDMLDHPLL
        . .. ..  . .|.  .  .   .|.| |||. .|.|.| ..| |.|  |.|. .
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 26742.AA CAMKL 88-341 27 2.4e-58 184.72 In-house 1-297 (297) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-297/297
Sequence Identity: 27% (83 aa)

YCLPDIIGKGYSSKVYRGKN-ETTGDTVAVKVIDMKGIK-NEVQSFL-----------LKNEISVLKKLN---NINCLKLFDVFHTANN------TYIIT
| . . .|||  .||  ...  |||  ||.|.|| |.|. ... .             .. ||. .|.||     |  ||..|. | ..       |...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCDHGD--LKELITKY----GTFSEKPAVKILKHLLNGLDEMQNKGIIHRDLKLANILVK-EG--IPKIADFGFS---KDL-NAEPCKFYYNVGTPMYM
| |. |.  | . | |     | ..|. | .. . .. ... . ..||.|||.|. |||.   |    ||.|||||   ..  . .  |.    |.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

CPQSLTK--NEYS-FKSDIWSIGVLFYEMIYNITPWVADT-------EKQLVDKMTSIPVSFPATP-IVSEESKDFIRGCLTIDESKRFSLKDMLDHPLL
.|  . .   .|  .| ||||.||. | |..   |. .||        . .  ... .   .|  .  || . .|.||. |. . .||..... . || .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 26742.AA Ciliate-E2a 88-341 28 1.5e-56 165.01 In-house 1-275 (275) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-275/275
Sequence Identity: 28% (80 aa)

YCLPDIIGKGYSSKVYRGKNETTGDT-VAVKVIDMKGIKNEVQSFLLKNEISVLKKLNNINCLKLFDVFHTANNTYIITEFCDHGDLKELITKYGTFSEK
| . ..||||   .||  .   ||.  ...|.|. |   .. ... ..|||. ...|.. |..||..|. . || |...|.|. |.|.. | . ..| |.
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--PAVKILKHLL-NGLDEMQNKGIIHRDLKLANILVK----EG----IPKIADFGFSKDLNA-EPCKFYYNVGTPMYMC------PQSLTKNEYSFKSDI
   . .|.. ||  ||  |....|.|||||. ||| |    ..      ||.|||.... .  |. . .  .||| |.       .. |... |. | |.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSIGVLFYEMIYNITPWVADTEKQLVDKMTSIPVSFPATP---IVSEESKDFIRGCLTIDESKRFSLKDMLDHPLL
||.|| || ...  .|  . |... . .      .|  .     .| | ||.... |  | .||.. .. |.||  
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 26742.AA Ciliate-E2c 88-341 26 1.3e-55 191.02 In-house 1-310 (310) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-310/310
Sequence Identity: 26% (83 aa)

YCLPDIIGKGYSSKVYRG------KNETTG---------DTVAVKVIDMKGIKNEVQSFLLKNEISVLKKLNNINCLKLFDVFHTANNTYIITEFCDHGD
.    | |.|   |||..      .||  .            . |..|.. |.   .   ...||  .|..|. . .|  | . | .. |.|.|.|  |.
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT

LKELITKYGTFSEKPAVKILKHLLNGLDEMQNK-GIIHRDLKLANILVKEGIPKIADFGFSKDLNAEPCKFYY----NVGTPMYMCPQSLTK-NEYSFKS
|. .| .    .||  .   . ..... .   . .|.|||.| .||| ..|..|||||||||  . .  ....     .|||||| || |   |.|  ||
LEQYIYHKPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYYTEKS

DIWSIGVLFYEMIYNITPWV------------------ADTEKQLVDKMT---------------SIPVSFPAT--PIVSEESKDFIRGCLTIDESKRFS
|||| ||. |.|..   ||                   ..| |.|..                    ...||      .|.| |..|.  |  ||.||..
DIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEKRID

LKDMLDHPLL
 ..  .|...
WDEIFNHECI
Kinase 26742.AA STE 88-279 24 1.7e-43 150.86 In-house 1-262 (359) Show / Hide 
Range on Protein: 88-279
Range on HMM: 1-262/359
Sequence Identity: 24% (66 aa)

YCLPDIIGKGYSSKVYRGKNET---------------TGDTVAVKVIDMKGI--------------KNEVQSFLLKNEISVLKKLN--NINCLKLFDVFH
. . ..|||| . .||...|                 ||. .|.|.....                ||. .   ...||...||.|    |  | .. . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TA-------NNTYIITEFCDHGDLKELIT-KYGT-------------FSEKPAVKILKHLLNG-LDEMQNKGIIHRDLKLANILVKEGIPKIADFGFSKD
         .. .|. |..| | | ..|  |||.             |.|.   .|.. .| | |.   ...|||||.| ||||.     |..|||... 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

LNAE----------------PCKFYYNVGTPMYMCPQSLTK------NEYSFKSDIWSIGVLFYEMI
|. .                  | .  |||| .| |  ...      ..|..|.||||.| .  ||.
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase 26742.AA TyrKc 88-341 22 4.1e-16 37.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 88-341
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YCLPDIIGKGYSSKVYRGKNETTGDTVAVKVIDMKGIKNEVQSFLLKNEISVLKKL--NNINCLKLFDVFHTA-------NNTYIITEFCDHGDLKELIT
  | ...| |   .||.|.      .||||..             . .|.....||  .. | ..|. |  .           .|..|...|||||. . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KYGT-FSEKPAVKILKHLLNGLDEMQNKGIIHRDLKLANILVKEG-IPKIADFGFSKDLNAE-PC---KFYYNV----GTPM-----YMCPQSLTKNEYS
|..  .. |  ...     .| .    |..|||||   |.||.|. . ||.||| |.|.  .  .   | || .    |. .      | | .. .....
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FKSDIWSIGVLFYEMI-YNITPWVA-----DTEKQLVDKMTSI-----PVS-----FPATPIVSEESKDFIRGCLTIDESKRFSLKDMLDHPLL
.|||.|| ||. .|.  |  .|.        . .... .  .      | .     |   .. ..|  . .. |   | ..| . ..   | ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 26742.AA Pkinase_Tyr 88-235 25 6.9e-13 44.28 Pfam 1-161 (270) Show / Hide 
Range on Protein: 88-235
Range on HMM: 1-161/270
Sequence Identity: 25% (42 aa)

YCLPDIIGKGYSSKVYRGKNE----TTGDTVAVKVIDMKGIKNE--VQSFLLKNEISVLKKL-NNINCLKLFDVFH-TANN--TYIITEFCDHGDLKELI
  .   .|.|   .||.|.       |. .||||..  .  . .   ..|.   |....|.| .. | ..|  |          ||..|.. ||||..  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR--EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

TKY----GTFSEKPAVKILKHLLNGLDEMQNKGIIHRDLKLANILVK-EGIPKIADFGFSKDL
 |     . .. |  ...     .|..   .|..|||||   |.||. ... ||.||| ..|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase 26742.AA STE 310-341 41 6e-08 24.29 In-house 326-359 (359) Show / Hide 
Range on Protein: 310-341
Range on HMM: 326-359/359
Sequence Identity: 41% (14 aa)

VSEESKDFIRGCLTIDESKRFSLKDMLD--HPLL
.|.| ||||. ||..| .|| . ...|   || .
WSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 26742.AA Pkinase_Tyr 256-279 37 0.025164 8.5 Pfam 185-208 (270) Show / Hide 
Range on Protein: 256-279
Range on HMM: 185-208/270
Sequence Identity: 37% (9 aa)

SLTKNEYSFKSDIWSIGVLFYEMI
..  .... |||.|| ||| .|..
CINYGKFTTKSDVWSFGVLMWEIF