Gene 22049 (Tetrahymena)

22049

Species: Tetrahymena
Alias: 83.m00118, 638, PreTt22049, TTHERM_00599820, 22049, 3685.m00010
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
22049.AA Protein None 1192 None Fasta, JSON
22049.kin_dom Protein Kinase Domain None 266 None Fasta, JSON
22049.NA RNA None 3579 None Fasta, JSON

Protein domain

Protein domains of 22049.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 22049.AA ULK 1-266 31 7.8e-89 301.44 In-house 3-324 (324) Show / Hide 
Range on Protein: 1-266
Range on HMM: 3-324/324
Sequence Identity: 31% (102 aa)

MKHLLGKGTFGEVYICWREKEPS----IKFACKIIPISNLEQDKL---------KQSLEEGRLLMLA--QGKN--IVPMITFIKSP--NNFYYITQFCNQ
..| ||||.|| |. .. ... .     ..|||.|..... ..|.         ..  |   . .|   ...|  || .. . ...  ||.| |. .||.
LNHCLGKGSFG-VKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNG

GNLQEFINKNQK--------IINEGFLLNIFKMICVGYYEQIFSKNLIHRDIKPENILIHDGIPL-------------IADFGFAKHLDDN--EVQIEQT
|.|...|.||.|        ...|   ...||   . ..  . ..| |||||||.|||||.|.|              |||||||||.|.|  | |. ||
GDLEQYIKKNKKLPETEEKKRLSEQEAIQFFK-QICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YK------CTPMYASPQIYILE-EKCTYS-YKADIYSFGVMLYQMIYGYVP-GKPQSRIDVQKFMKKIKEQGTK-----IIDFPSDHK-----FQVSFET
..      .||.| .|||   . |.. |. ||.||.|.|...|.|.||..|  ..  . .... ..| ...| |     | . | ...      ..| |.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNG-KEQQIYIKNQPIQFPKPPKDPKISPEC

KQAIKSMMEYKEENRISIEELLNHKMF
|. |. |..|.|. |||.||..||. |
KDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 22049.AA ULK 1-266 30 9.5e-88 297.82 In-house 3-329 (329) Show / Hide 
Range on Protein: 1-266
Range on HMM: 3-329/329
Sequence Identity: 30% (102 aa)

MKHLLGKGTFGEVYICWREKEPS-----IKFACKIIPISNLEQDKLK---------QSLEEGRLLMLA---QGKN----IVPMITFIKSP--NNFYYITQ
..| ||||.||  . .. ... .     .|.|||.|... . |..              |   . .|    ..||    || .. . ...  ||.| |. 
LNHCLGKGSFG--KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCNQGNLQEFINKNQK---------IINEGFLLNIFKMICVGYYEQIFSKNLIHRDIKPENILIHDGIPL-------------IADFGFAKHLDDN--EV
.||.|.|...|.||.|         ...|   ...||   . ..  . ..| |||||||.|||||.|.|              |||||||||.|..  | 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFK-QILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

QIEQTYK------CTPMYASPQIYILE-EKCTYS-YKADIYSFGVMLYQMIYGYVP-GKPQSRIDVQKFMKKIKEQGTKI--------IDFPSD-HKFQV
|...|..      .||.| .|||   . |.. |. ||.||.|.|...|.|.||..|  ..  . .. ....| .... ..        ..|| |  . |.
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SFETKQAIKSMMEYKEENRISIEELLNHKMF
| |.|. |. |..|.|. |||.|||.||. |
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 22049.AA Ciliate-E2 1-266 23 3.7e-52 177.33 In-house 3-365 (365) Show / Hide 
Range on Protein: 1-266
Range on HMM: 3-365/365
Sequence Identity: 23% (91 aa)

MKHLLGKGTFGEVYIC--WREKEPSI---------------KFACKIIPISNLEQDKLKQSLEEGRLL--------------MLAQGKN--IVPMITFIK
   ..|.|.|| || |  |.... ..               |.. ||. . ........| . | ...              .| | ..  |. |. . .
FIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQ

--SPNNFYYITQFCNQGNLQEFINKNQKI----------INEGFLLNIFKMICVGYY--------------EQIFSKN-LIHRDIKPENILIHDGIPLIA
  . ||.|... .|..|.|...|..|.|           ..|   ..|.| |. |.               | . |||  |||||||||||.    . |.
EKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKII

DFGFAKHLDD-----------------NEVQIEQTYK-------------CTPMYASPQIYILEE------KCTYSYKADIYSFGVMLYQMIYGYVPGKP
|||..| .||                 |.  . ..|              .||.| .|.|.  ..      .  |.||.||.|.||.||.|..|. |   
DFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--

QSRIDVQKFMKKIKEQGTKIIDFPSDH--------------KFQVSFETKQAIKS----MMEYKEENRIS-IEELLNHKMF
            ....  . ||||. .              ....| |.|. ||     |.....|.||. .|..|||. |
------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 22049.AA S_TKc 1-266 26 1.8e-48 168.23 SMART 3-231 (231) Show / Hide 
Range on Protein: 1-266
Range on HMM: 3-231/231
Sequence Identity: 26% (75 aa)

MKHLLGKGTFGEVYICWREKEPSIKFACKIIPISNLEQDKLKQSLEEGRLLMLAQGKNIVPMITFIKSPNNFYYITQFCNQ--GNLQEFINKNQKI----
.  ..|||.||.|| |.  |    ..|.|||.         .. . | ..|.  . .||| .. .. . ...| .. .|..  |.| ..| |...     
ILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-INEGFLLNIFKMICVGYYEQIFSKNLIHRDIKPENILIHDGIPLIADFGFAKHLDDNEVQIEQTYKCTPMYASPQIYILEEKCTYSY-KADIYSFGVML
 ..|     ... || .  | . |.. ||||.||||||. .    |.|||.|..|         |.  || | .| .        |.. |.|..|.|..|
PFPE-HARFYMYQICCA-LEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL--------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCIL

YQMIYGYVPGKPQSRIDVQKFMKKIKEQGTKIIDFPSDHKFQVSFETKQAIKSMMEYKEENRISIEELLN-------HKMF
| |..|| |       ..|. .|||.                 | | |. |. ....  |.|... |.|.       |  |
YEMLCGYPPFP-----QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 22049.AA Ciliate-E2-Unclassified 1-266 23 2.9e-47 161.98 In-house 3-352 (352) Show / Hide 
Range on Protein: 1-266
Range on HMM: 3-352/352
Sequence Identity: 23% (83 aa)

MKHLLGKGTFGEVYICWREKEPSIKFACKIIPISNLEQDKLKQS----------LEEGR-------------LLMLAQGKNIVPMITFIKSPNNFYYITQ
. . .|.| ||.|| | ..|.   ..| |..  ..   .|....          ...               .|   .  .|| |.   .. .|.| ...
IIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVME

FCNQGNLQEFINKN----------------QKIINEGFLL-----NIFKMICVGYYEQIFSKNLIHRDIKPENILIHDG----IPLIADFGFAKHLDDN-
.|..|.|...|.|.                .||. |   .     ..|. |..|    . ..| |||||||||||....     . |.|||..|....| 
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

-------------EVQIEQTYKCTPMYASPQ---IYILEEKCTYS---YKADIYSFGVMLYQMIYGYVPGKPQSRID-------------VQKFMKKIKE
               |. .|  .||.| . |     .|...  .    ||.||.|.|| ||.|..|| | . .....              . . ..||.
NCDTNQQQKMQIWKQQMMWTFCGTPNYMP-QYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

QGTKIIDFPS--DHKFQVSFETKQAIK----SMMEYKEENRISIEELLNHKMF
. ...  ||   ..| ..|.| |  |.    .|.... ..||..|..|||  |
KNIQFPKFPWQQIPK-HWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 22049.AA Ciliate-E2c 1-266 29 1.5e-46 160.97 In-house 3-310 (310) Show / Hide 
Range on Protein: 1-266
Range on HMM: 3-310/310
Sequence Identity: 29% (93 aa)

MKHLLGKGTFGEVYIC--WREKEPSIK-------FACKIIPISNL--EQDKLKQSL----EEGRLLMLAQGKNIVPMITFIKSPNNFYYITQFCNQGNLQ
    ||.|..| ||      ..  .|.       || |... .|.   ....|  .     |  ...    ..|. .. ...  ...| |. .||.|.|.
RNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGTLE

EFINKN-QKIINEGFLLNIFKMICVGYYEQIFSKNLIHRDIKPENILIHDGIPLIADFGFAKHLDDNEVQIEQ---TYKCTPMYASPQIYILEEKCTYSY
 .| .. .  .||.  |  |. |  .  . .  || .||||||||||||.|.. ||||||.|  .| ..|. |   |.  |||| .||  ||| |  | .
QYIYHKPK--PNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQ--ILEGKNYYTE

KADIYSFGVMLYQMIYGYVPGK---------------PQSRIDVQKFMKKIKE------------QGTKIIDFPSDHKFQVSFETKQAIKSMMEYKEENR
|.|| | ||.||.|..   | .               |..   ...  . |.|              |. | || .  . .| |.|| |. | .. ||.|
KSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEKR

ISIEELLNHKMF
|. .|. || ..
IDWDEIFNHECI
Kinase 22049.AA Pkinase 2-266 24 1.9e-41 147.66 Pfam 4-293 (293) Show / Hide 
Range on Protein: 2-266
Range on HMM: 4-293/293
Sequence Identity: 24% (73 aa)

KHLLGKGTFGEVYICWREKEPSIKFACKIIPISNLEQDKLKQSLE--EGRLLMLAQGKNIVPMITFIKSPNNFYYITQFCNQG----NLQEFIN-KNQKI
.  .|.|.||.||.| . ...  ..|.|||. .. . .|... .   | ...   . .||| .. .  .... | .. .|. |     | ..|  .... 
GRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGC

I--NEGFLLNIFKMICVG-YYEQIFSKNLIHRDIKPENILIH-DGIP----LIADFGFAKHLDDNEVQIEQTYKCTPMYASPQIYILEEKCTYSYKADIY
.   |  . .... |. | .|  . |.. ||||.|||||||. .| .     |.|||.||..|    .  .|. .|| |..| .  . .   |..|.|..
FYFSEWECKFYMYQILRGLEY--CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVDMW

SFGVMLYQMIYGYVPGKPQ----SRIDVQKFMKKIKEQGTKIIDFPSDHKFQVS-----------------FETKQAIKSMMEYKEENRISIEELLNHKM
|.|..||.|. |. | . .    . .| .. ...|..   ....|... .  .|                  | |. ||.. ... . |...|..|.|. 
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMG---PPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase 22049.AA CAMK 4-266 19 8.7e-36 112.27 In-house 1-425 (425) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)

LLGKGTFGEVYICWREKEPS-----------IKFACKIIPISNLE--------------------------QDKLKQSLEEGRLLMLAQ-------GKNI
 ||.|.||.|. | . . .             |.|.|||. . |                           . ..|. . | ..... |        .||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VPMITFIKSPNN-------------------FYYIT---QFCNQG----NLQEFINKNQK---------IINEGFLL------NIFKMICVGYYEQIFS-
. .. .. .|..                   .| ..    .|  |     | ..| .. .         |. | . .       .|.         | | 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQ--------ICSA

------KNLIHRDIKPENILI-HD-----------------GIPLIADFGFAKHLDDNEVQI----------------------EQTYKCTPMYAS-PQI
      .| .|||.||||||. ..                 .   |.|||||...|..| .                        .|.  || |.. | .
VHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEV

YI-----------LEEKCTYSYKADIYSFGVMLYQMIYGYVPGKPQSRI----------DVQKFMKKIKEQGTKIIDFP------------SD------H
             .|||  |..|.|. | ||.|| |  || |    ..           . .. ..||..     ....             |      |
LNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFH

KFQVSFETKQAIKSMMEYKEENRISIEELLNHKMF
. .|| | |. |..|...  |.|..||. |||. .
H-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 22049.AA Ciliate-E2b 4-201 31 2.9e-34 101.62 In-house 6-209 (272) Show / Hide 
Range on Protein: 4-201
Range on HMM: 6-209/272
Sequence Identity: 31% (64 aa)

LLGKGTFGEVYICWREKEPSIKFACKIIPISNLEQDKL-KQSLEEGRLLMLAQGKNIVPMITFIKSPNNFYYITQFCNQGNLQEFINKNQK--IINEGFL
.||.| || ||  |. |. .  .| | |... . |  . |. | |  .|  ..  .|.  |   |. .. | .  ||| . | . |  ...   ...   
KLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVI-REIGRLLLSTYDS

LNIFKMICVGYYEQIFSKNLIHRDIKPENILIHD-GIPLIADFGFAKHLDDNEVQIEQTYKC--TPMYASPQIYI--LEEKCTYSYKADIYSFGVMLYQM
. ... || .  .   ..| |.||||||||...  | . ..|.| |||..... |.  |.    || |  |.|          |.||.||.|.|..|| .
QFYIASICLCLEYLH-NQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEF

IYGYVP
. ||||
MCGYVP
Kinase 22049.AA AGC 117-266 22 2.9e-32 79.43 In-house 171-395 (395) Show / Hide 
Range on Protein: 117-266
Range on HMM: 171-395/395
Sequence Identity: 22% (53 aa)

S-KNLIHRD-IKPENILIHD-GIPLIADFGFAKHLDDNEV-----------------------------------------------QIEQTYK-C---T
| .. |||| .||||||. . |   ..|||..| . ...                                                . ..|.  |   |
SHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCT

PMYASPQIYILEEKCTYSYKADIYS--FGVMLYQMIYGYVP---GKPQSRI-----DVQKFMKKIK------EQGTKII-----DFPSDHKFQVSFETKQ
| | .| |        |.. .|..|  .|...|.|..|| |     ||  .     .  . ..||.      ... |.      .|| | .|  | | | 
PEYMAPEIL-------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQE-NRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWF--SPEAKD

AIKSMMEYKEENRIS----------IEELLNHKMF
 || ...   |.|.           .||. ||. |
LIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 22049.AA Ciliate-E1 5-186 26 5.5e-25 78.47 In-house 1-202 (202) Show / Hide 
Range on Protein: 5-186
Range on HMM: 1-202/202
Sequence Identity: 26% (53 aa)

LGKGTFGEVYICWREKEPSIKFACKIIPIS-NLEQDKLKQSLEEGR-LLMLAQGKNIVPMITFIKSPNN--FYYITQFCNQGNLQEFI-----------N
.|.| |. |..   ..   .. | ||| .  | .|... . ..|   .... . ..|. .| .||. .|  .. |...|..  ....            .
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ

KNQKIINEGFLLNIFKMICVGYYEQIFSKNLIHRDIKPENILI-HDGIPLIADFGFAKHLDDNEVQIEQTYKCTPMYASPQIYI----LEEKC-TYSYKA
.||.  ..  ...|.. .  | .......|.|||||||.|||| ..|. ...||| .| |  |. |  |    | .|..|. |      ..|. ...|| 
QNQNQFTFQQKMQIIFQLIDG-LIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DIY
|||
DIY
Kinase 22049.AA CAMKL 117-266 29 8.1e-22 66.28 In-house 145-297 (297) Show / Hide 
Range on Protein: 117-266
Range on HMM: 145-297/297
Sequence Identity: 29% (47 aa)

SKNLIHRDIKPENILIH-DG--IPLIADFGFAKHLD---DNEVQIEQTYKCTPMYASPQIYILEEKCTYSYKADIYSFGVMLYQMIYGYVPGKPQSRI--
|.. .||||||||||.  .|     |.||||. . .   ... |   |   .| |..| |.   .|  . .|.|| | ||.|| |..||.| . ..    
SHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQ

---DVQKFMKKIKEQGTKIIDFPSDHKFQVSFETKQAIKSMMEYKEENRISIEELLNHKMF
   .. ....||... ...     .. ..|| . .. |..|.. . | |..|....||. .
GKDNI-YLYWKIMCG-YYP-----PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 22049.AA TyrKc 1-266 19 4.3e-12 -27.15 SMART 3-280 (280) Show / Hide 
Range on Protein: 1-266
Range on HMM: 3-280/280
Sequence Identity: 19% (58 aa)

MKHLLGKGTFGEVYICWREKEPSIKFACKIIPISNLEQDKLKQSLEEGRLLMLA--QGKNIVPMITFIKSP-------NNFYYITQFCNQGNLQEFINKN
... || | ||||| .       |. | | .  .      ..  ..| |...    . .||| ..  . ..          . .. ..  |.|.... |.
LGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

QKIINEGFLLNIFKMICVG--YYEQIFSKNLIHRDIKPENILIHDG-IPLIADFGFAKHLDDN-------EVQIEQTYKCTPM-----YASPQIYILEEK
.. ..   ||..   |. |  | ..    |.||||.   |.|.... .  |.||| .. ..|        ..   .. |.. .       .|       .
RPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NY

CTYSYKADIYSFGVMLYQMI-YGYVPGKP---QSRIDVQKFMKKIKEQGTKIIDFP----SDHKFQVSFETKQAIKSMME----YKEENRISIEELLNHK
.... | |..||||... .  ||  |      |  .. |  ....|. .   .       |   |    .  ... ..|.    .. |.| . .|.  |.
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMS---F---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

MF
 |
CF
Kinase 22049.AA AGC 1-84 14 1.1e-07 14.4 In-house 1-128 (395) Show / Hide 
Range on Protein: 1-84
Range on HMM: 1-128/395
Sequence Identity: 14% (19 aa)

MKHL--LGKGTFGEVYICWREKE-----PS-IKFACKIIPISN-LEQDK---LKQSLEE------------GRLLMLAQG----------KNIVP-MITF
 . |  .|||.||.|| . |.|.      .   .|.|..  .    ..|   ... . |             . |.....           .||  .   
FEFLKVIGKGSFGKVYLV-RKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYS

IKSPNN--FYYITQFCN--------QGNL
 .....   | . ....         | .
FQDKDHTYLYFVMEYMPRYVNDLYCGGGC
Kinase 22049.AA CAMKL 5-91 21 2e-06 16.44 In-house 7-117 (297) Show / Hide 
Range on Protein: 5-91
Range on HMM: 7-117/297
Sequence Identity: 21% (24 aa)

LGKGTFGEVYICWREKEPSIKFACKIIP--ISNLEQDKLKQSLE-----------EGRLLMLAQ---GKNIVPMITFIKSPNN------FYYITQFCNQG
||||.||.|  .. .. . .| | |||     .... ..|  .            | ..... .    .||. .   |  |..      .| ..  |  |
LGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGG

N--LQEFINKN
.  |...| |.
EMDLFDYIVKH