Gene 22048 (Tetrahymena)
22048
Sequence
Protein domains of 22048.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 22048.AA | ULK | 17-279 | 28 | 3.1e-80 | 272.89 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-324/324 Sequence Identity: 28% (94 aa) IEMNNQIGSGQHG-SVYMAHRKDFG--VKKLACKIQQ--------SNRN------QIKEEISIIKEVN---GIY--IAEVLDVYKTS--SYIYIFMRHYQ ...|...|.|. | || . |. . .. |||. . .... ..| ||.|.|. . . . | . .|...|| .|||.| . YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN KGDLDHYLQENRL--------KLSEKDILTIFYKIIYGYFQNIYNRQIIHRDIKASNILMDELDPY-------------ITDFGLSIKFQD--LQKEVNP |||..|...|. .|||. .. .| | | .|. .....||||||| .|||. . .|. |.|||.. .... ... .. GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFF-KQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ YFK------GTLFYSSPQIQGLE--GSIYS-YKTDIYSLGILLYYMLYSQYP-ENSKQLRDYEKFMQKLKNEGNLHA----IKFPKTKEN-----STISL ... || | .|||. . . |. ||.||.|||...|.||| .|| ... .|.. .|||.| | . . || . . . || TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNG-K-EQQIYIKNQPIQFPKPPKDPKISP ETKNLILQMITYKEEDRIEITELLNHKVF |.|.|| .|..|.|.|||...|..||..| ECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | 22048.AA | ULK | 17-279 | 29 | 9.9e-80 | 271.19 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-329/329 Sequence Identity: 29% (97 aa) IEMNNQIGSGQHGSVYMAHRKDFG---VKKLACKI------QQSNRN--------QIKEEISIIKEVN----GIY----IAEVLDVYKTS--SYIYIFMR ...|...|.|. | || . |. . ..| |||. .|.| . ..| || |.|. . ... | . .|...|| .|||.| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME HYQKGDLDHYLQENRL---------KLSEKDILTIFYKIIYGYFQNIYNRQIIHRDIKASNILMDELDPY-------------ITDFGLSIKFQ-D-LQK . |||..|...|. .|||. .. .| | | .|. .. ..||||||| .|||... .|. |.|||.. ... | ... YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFF-KQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ EVNPYFK------GTLFYSSPQIQGLE--GSIYS-YKTDIYSLGILLYYMLYSQYP-ENSKQLRDYEKFMQKLKNEGNLHA--IKFPKTK-----ENSTI ... ... || | .||| . . |. ||.||.|||...|.||| ..| ... .|....|||.| .. .. || ... .. .| QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI SLETKNLILQMITYKEEDRIEITELLNHKVF | |.|.|| .|..|.|.|||...||.||..| SPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | 22048.AA | Ciliate-E2 | 17-279 | 23 | 4.8e-52 | 176.94 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-365/365 Sequence Identity: 23% (91 aa) IEMNNQIGSGQHGSVYMA-HRKD---------------------FGVKKLACKIQ-QSNRNQIKEEISIIKEVN----------------GIYIAEVLDV .. ...||.|..|||| . ..|. . .|. | ||. ... .||| ||.|..|.| .| . .. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YK--TSSYIYIFMRHYQKGDLDHYLQENRLK----------LSEKDILTIFYKIIYGY--------------FQNIYNRQ-IIHRDIKASNILMDELDPY .. . ..||. | .| ||| .|...|..| ..|| |..|...|..|. .. . .. ||||||| .|||. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK ITDFGLSIKFQDL---------QKEVNPYF----------------------KGTLFYSSPQIQGLEG-------SIYSYKTDIYSLGILLYYMLYSQYP |.||||| |..| .|. . ||. | .|.| . .. |.|| ||.|||..||.||. ..| IIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP ENSKQLRDYEKFMQKLKNEGNLHAIKFPKTK-------------ENSTISLETKNLILQ----MITYKEEDRIE-ITELLNHKVF |. . ... |.||. . .. .|.|.|.|| . |. ...| || . ..|||. | F------------QQQIKQCK---IDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 22048.AA | S_TKc | 17-279 | 25 | 5.2e-44 | 153.44 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-231/231 Sequence Identity: 25% (70 aa) IEMNNQIGSGQHGSVYMAHRKDFGVKKLACKIQQSNRNQIKEEISIIKEVNGIYIAEVLDVYKTSSYIYIFMRHYQK--GDLDHYLQENRLK-----LSE |. ..||.| |.|| .. |. .. |.|| ..|. ||.| |. . .| .||. . ...|..| . ||| .|..... . ..| YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE KDILTIFYKIIYGYFQNIYNRQIIHRDIKASNILMDELDPYITDFGLSIKFQDLQKEVNPYFKGTLFYSSPQIQGLEGSIYSY-KTDIYSLGILLYYMLY .. ..| |. . . . ...|||||.| .|||.|| |.||||. .. | ||..| .| . |.. | |..|.|..|| ||. -HARFYMYQICCA-LEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL--------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLC SQYPENSKQLRDYEKFMQKLKNEGNLHAIKFPKTKENSTISLETKNLILQMITYKEEDRIEITELLN-------HKVF . | .... ..|.. | | |..| .. .. |.|. . |.|. | | GYPPFP-----QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 22048.AA | CAMK | 22-279 | 17 | 1.5e-36 | 114.75 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 22-279 Range on HMM: 1-425/425 Sequence Identity: 17% (76 aa) QIGSGQHGSVYMAHRKDFGV-----------KKLACKI--------------------------------QQSNRNQIKEEISIIKE-------VNGIYI ..|.|. | |. . .| . .| |.|| ....| ... ||.| | .. | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI AEVLDVYK------------TSSY--------IYIFM---RHYQKG----DLDHYLQENRL--------------KLSEKDILTIFYKIIYGYFQNIYNR ..|| | |. .|..| . . | || |..|.. ...|.. ..| |. . . . .. IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSA-VHYCHSH QIIHRDIKASNILMDE------------------LDPYITDFGLSIKFQDL--------QKEVNPY---------------FKGTLFYSS-PQIQGLEGS |.|||.| |||.|. . |.|||...||.. .|. . | ||. | . | . |.|. NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-MHNQWTTPTEGQKMKTFCGTPEYMAAPEV--LNGK I--------------YSYKTDIYSLGILLYYMLYSQYPENSK-QLRDYE--------KFMQKLKNEGNLHAIKFPKTK-----------------ENSTI |..|.|. |.|..|| || .| ... . ...| . . . .|. . . .. .. .. .. GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FV SLETKNLILQMITYKEEDRIEITELLNHKVF | | |.|| .| .. |.|. |.. |||. . SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 22048.AA | Pkinase | 17-279 | 24 | 2e-35 | 126.31 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-293/293 Sequence Identity: 24% (73 aa) IEMNNQIGSGQHGSVYMAHRKDFGVKKLACKIQQSNRNQIKE--------EISIIKEVNGIYIAEVLDVYKTSSYIYIFMRHYQKG----DLDHYLQ-EN .. .|||| |.|| .|.|. | . |.|| .. .. ||.| |..| .| . .|.. ....||. | . ..| || .|.. .. YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR RLKL--SEKDILTIFYKIIYGYFQNIYNRQIIHRDIKASNILMD-ELDP----YITDFGLSIKFQDLQKEVNPYFKGTLFYSSPQIQGLE-GSIYSYKTD . .. ||... ..| |. | . .... |||||.| .|||.| . .. |.||||. .|. .. . | ||..| .| . . |. |..| | HGCFYFSEWECKFYMYQILRG-LEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVD IYSLGILLYYMLYS-QYPENS----KQLRDYEKFMQKLK-----NEGNLHAIK--------FPKTKENSTISLETKNLILQMITYKEEDRIEITELLNHK ..|.|..||.|| .. . ....... .... .. ... | | .. .| | | .| ..... ..|. ....|.|. MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHP VF | WF |
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Kinase | 22048.AA | Ciliate-E2-Unclassified | 17-279 | 24 | 9.7e-35 | 117.94 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-352/352 Sequence Identity: 24% (86 aa) IEMNNQIGSGQHGSVYMAHRKDFG---VKKLACKIQQSNRNQIKE---------EISIIK----------------EVNGIYIAEVLDVYKTSSYIYIFM ... |||.|..|.||.. .|. . ..| ..|||. ...||.. |. ..| . ..| ... .. .||| | YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM RHYQKGDLDHYLQ-------------ENRLK---LSEKDIL-----TIFYKIIYGYFQNIYNRQIIHRDIKASNILMDEL----DPYITDFGLSIKFQDL . ||| |.. .|... ..|. .. ..|. |. | . ... ||||||| .|||.|. . |.|||.|.| |. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN --------------QKEVNPYFKGTLFYS----SPQIQGLEGSIYS----YKTDIYSLGILLYYMLYSQYPENSKQLRD------------YEKFMQKLK ... | ||. | .| . |.| |. || ||.|||..||.||. .|| .... . |.| ... . NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEV--LQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI NEGNLHAIKFPKTKENSTISLETKNLIL----QMITYKEEDRIEITELLNHKVF ...|. |||. . ..| | |..| .|. .. . || . ..||| | KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 22048.AA | Ciliate-E2c | 17-279 | 29 | 4.7e-32 | 109.67 | In-house | 1-310 (310) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-310/310 Sequence Identity: 29% (92 aa) IEMNNQIGSGQHGSVYMAHRKD--------------FGVKKLACKI------QQSNRN-QIKEEISIIKEVNGIYIAEVLDVYKTSSYIYIFMRHYQKGD |. || |||. |.|| | . | .| .. |. ... |. || . |. | .| . | .|.. ||..| |. IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT LDHYLQEN-RLKLSEKDILTIFYKIIYGYFQNIYNR-QIIHRDIKASNILMDELDPYITDFGLSIKFQDLQKEVNP---YFKGTLFYSSPQIQGLEG-SI | |. .. ... || .|. | ||.. |. .. |.||||| .||| . . | |||.| ..||. . . || .|..||| ||| LEQYIYHKPKPN--EKQCLYYFSQIISA-FKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQI--LEGKNY YSYKTDIYSLGILLYYMLYSQYPEN---------------SKQLRDYEKFMQKLKNEGN-----------LHAIKFPKTKENSTISLETKNLILQMITYK | .| || |||..|||||. .| . . .. | .. .| |.||. |.. ||.|.| || |. . YTEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQN-ISQEVKQLIHKMLQVD EEDRIEITELLNHKVF ||.||. |. || . EEKRIDWDEIFNHECI |
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Kinase | 22048.AA | CAMK-Unique | 17-279 | 19 | 4.7e-26 | 82.83 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-363/363 Sequence Identity: 19% (70 aa) IEMNNQIGSGQHGSVYMAHR----KDFGVKKLACKIQQSNRNQI-------------------KEEISIIKEVNGIYIAEVLDV----YKTSS------- ..|.. ||.| | || .. | . .|.. . ...... . |.|..| | |. | ...|. . .. YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI --------YIYIFMRHYQKGDLDHYLQEN-------------------RLKLSE--KDILTIFYKIIYGYFQNIYNRQIIHRDIKASNILMDELDP---- |.||.| . |.||| ..|.. . ..|| |...|. .. . .|.|||.|. ||. . . IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSA-VAYMHSQDIVHRDLKLENIMVCYSFKDNNH -------------YITDFGLSIKFQDLQKE-VNPYFKGTLFYSSP--------------QIQGLEGSIYSYKT----DIYSLGILLYYMLYSQYP-ENSK ..||||. ... ... . . ||. | .| .. .... |... || ||| ..|||| | . . HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEV--INMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCEC QLRDYEKFMQKLKNEGNLHAI-KFPKTKENST--ISLETKNLILQMITYKEEDRIEITELLNHKVF |||| .. . . .|.. ..... || | |... . |.. |. . ||| | . EDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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Kinase | 22048.AA | STE | 17-279 | 18 | 6.9e-26 | 88.45 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-359/359 Sequence Identity: 18% (68 aa) IEMNNQIGSGQHGSVYMAHRKD-------------------FGVKKLACKIQQ----------------SNRNQIKEEISIIKEVN--GIYIAEVLDVYK | .||.| |.|| | ... . .|.. . .. ....||..||.| |. | .| . .. | WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF TS-------SYIYIFMRHYQKGDLDHYLQENRLKLS-------------EKDILTIFYKIIYG--YFQNIYNRQIIHRDIKASNILMDELDPYITDFGLS ....|.| . | || .... .. |. | .| . |. | |. . |||||||..|||. ..|||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL----VKLCDFGVC IKFQD---------------LQKEVNPYFKGTLFYSSPQIQGLEGSI----YSYKTDIYSLGILLYYMLYSQYPENS-KQLRDYEKFMQKLKNEG----- ...| ... . | || . .| . .|. |..| ||.|||... |. ..| . .| . .... . . GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL ---NLHAIKFPKTKE--------------NSTISLETKNLILQMITYKEEDRIEITELLN--HKVF | . ..| . . . | | |. | . .. ..| ..||. |. . CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | 22048.AA | MARK | 18-207 | 31 | 5.1e-19 | 58.97 | In-house | 2-200 (262) | Show / Hide |
Range on Protein: 18-207 Range on HMM: 2-200/262 Sequence Identity: 31% (65 aa) EMNNQIGSGQHGSVYMAHRKDFGVKKLACKIQQ-------SNRNQIKEEISIIKEVNGIYIAEVLDVYK--TSSY-IYIFMRHYQKGDLDHYLQEN--RL .| .|| | .. |. |. | | .| | || . ... .. ||.| | .. .| . ..| |.. ||. | .. .|.| .|... . KMLKTIGHGSYAKVKLACHKHTG-RKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG- KLSEKDILTIFYKIIYGYFQNIYNRQIIHRDIKASNILMDEL---DPYITDFGLSIKFQDLQKEVNPYFKGTLFYSSPQIQGLEGSIYS-YKTDIYSLGI .|.|.. .|| |... . .. |.|||||. |||.|| . |.|||.||... || | ||. | .|.| ... | .|.||.|||. RLHEEEARRIFRQIVSA-VNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLN--TFCGTPPYMAPEI--FLKKPYDGPKVDIWSLGV LLYYML .||.|. VLYFMV |
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Kinase | 22048.AA | CAMKL | 129-279 | 26 | 9.8e-18 | 53.03 | In-house | 145-297 (297) | Show / Hide |
Range on Protein: 129-279 Range on HMM: 145-297/297 Sequence Identity: 26% (44 aa) NRQIIHRDIKASNILMDELD---PYITDFGLSIKFQD--LQKE-VNPYFKGTLFYSSPQIQGLEG-SI-YS-YKTDIYSLGILLYYMLYSQYP--ENSKQ .. |.|||||. ||| || . |.|||.|..... ... | |.. | .| | ..| | .|.|| |.|..|| |.. ..| . . . SHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEI--FQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN LRDYEKFMQKLKNEGNLHAIKFPKTKENS---TISLETKNLILQMITYKEEDRIEITELLNHKVF . |. .| .|. .. .. .| . ..|| .| . . |.|. | ...||. . -K------QGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | 22048.AA | TyrKc | 17-279 | 20 | 7.6e-11 | -47.33 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 17-279 Range on HMM: 1-280/280 Sequence Identity: 20% (63 aa) IEMNNQIGSGQHGSVYMAHRKDFGVKKLACKIQQ--SNRNQIKEEISIIKEV--NGIYIAEVLDVYKTS-------SYIYIFMRHYQKGDLDHYLQENRL |... ..|.|. | || .. | . | | . . | . .|..| ... . | . | .. ..| | . .|||..||...| ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP KLSEKDILTIFYKIIYGYFQNIYNRQIIHRDIKASNILMDELD-PYITDFGLSIKFQDL--------QKEV----NPYFKGTLFYSSPQIQGLEGSIYSY ||. || | . . | | . . ...||||. | |.| .| |.||||| . | . . . . . .| .... KLCMKDLLSFCWQIACG-MEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTT KTDIYSLGILLYYML---YSQYPE------NSKQLRDY---EKFMQKLKN----EGNLHAIKFPKTKENSTISLETKNLILQMITYKEEDRIEITELLNH |.|..| |.... .. . ||. . .... | . | . .| | . . | ....| .. ||| .|. | KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------F------VCCPDEMYQIMKQCWHEDPEDRPTFSEI--H KVF . | ECF |
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Kinase | 22048.AA | Pkinase_Tyr | 17-113 | 25 | 6e-06 | 20.77 | Pfam | 1-114 (270) | Show / Hide |
Range on Protein: 17-113 Range on HMM: 1-114/270 Sequence Identity: 25% (29 aa) IEMNNQIGSGQHGSVYMAHRK--DFG------VKKLACKIQQSN--RNQIKEEISIIKEV-NGIYIAEVLDVYK-TSSY--IYIFMRHYQKGDLDHYLQE |... ..|.|. |.||... | . . ||.| . ... | .|..| |. . | . | . ||| | . ..|||..||.. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK N---RLKLSEKDIL . . .|. ||.| HREDKQPLTMKDLL |
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Kinase | 22048.AA | CAMKL | 15-116 | 20 | 0.000443 | 8.75 | In-house | 1-133 (297) | Show / Hide |
Range on Protein: 15-116 Range on HMM: 1-133/297 Sequence Identity: 20% (28 aa) YVIEMNNQIGSGQHGSVYMAHRKDFGVKKLACKIQQSNRNQ-------------------IKEEISIIKEVN---GIYIAEVLDVYKTSSY------IYI | |. ..| | | | .|. . . .| | || .. . |. ||.| | .| | ..|. |... ||. YRIGK--TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL FMRHYQKGD--LDHYLQENRL---KLSEKDILTIF .| . . |. | .|..... ...|.. .| VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYF |
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Kinase | 22048.AA | MARK | 248-279 | 34 | 0.002933 | 6.7 | In-house | 231-262 (262) | Show / Hide |
Range on Protein: 248-279 Range on HMM: 231-262/262 Sequence Identity: 34% (11 aa) ISLETKNLILQMITYKEEDRIEITELLNHKVF .| | .||| ...| |.|. |.|...|. . VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | 22048.AA | Pkinase_Tyr | 185-204 | 25 | 1.798989 | 2.22 | Pfam | 186-205 (270) | Show / Hide |
Range on Protein: 185-204 Range on HMM: 186-205/270 Sequence Identity: 25% (5 aa) LEGSIYSYKTDIYSLGILLY . .... |.|..| |.|.. INYGKFTTKSDVWSFGVLMW |