Gene 15044 (Tetrahymena)

15044

Species: Tetrahymena
Alias: TTHERM_00547920, 3729.m00048, 15044, 71.m00171, 342, PreTt15044
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
15044.AA Protein None 654 None Fasta, JSON
15044.kin_dom Protein Kinase Domain None 258 None Fasta, JSON
15044.NA RNA None 1965 None Fasta, JSON

Protein domain

Protein domains of 15044.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15044.AA ULK 18-275 34 2e-117 396.43 In-house 1-324 (324) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-324/324
Sequence Identity: 34% (111 aa)

YRIIKTLGKGQYG-TVYLAIDSNQ---QQQFAVKQIFSQSLINKKLN-------ELLNQELTIQKIIK---SQH--TVQVIEDFFDQNFKTHIIIQEYCD
| ... ||||..| .|| ... ..   .|..|.|.|  .....||..       .||..|  |.|..|   ...  .|. .. | ..|.. . ||.|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLEQYVKKYKY---------LPEAQAISYLKQLLQAFKELHFHKCMHRDIKPSNILISQGL-------------IKLGDFGFAKQLND----QDITKT
||||||| ||.|.         |.| .||...||....||||| |...||||||.||||. |              .|..||||||....    |....|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

AL------GTTITMAPEVFY----QQEYS-YEADMFSLGIVFYYMLFGQYPFKPQGLNPET----LFLQ--------IKEQNINFNL--NGVTISRNTQD
..      || ..|||...     |..|. |..|..|||..||.||.|.|||. .  |..       ..        || |.|.|..  ... || ...|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIKQMTAYDRKQRITWLGIYQHPAL
||..|  ||.|.||.|  |..|| .
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 15044.AA ULK 18-275 33 2e-113 383.15 In-house 1-329 (329) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-329/329
Sequence Identity: 33% (110 aa)

YRIIKTLGKGQYGTVYLAIDSNQ----QQQFAVKQIFSQSLINKK-------LNELLNQELTIQKIIK----SQH----TVQVIEDFFDQNFKTHIIIQE
| ... ||||..|.|| ... ..    ....|.|.| .|....|.       . .||..|  |.| .|    ...    .|. .. | ..|.. . ||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCDGGDLEQYVKKYKY----------LPEAQAISYLKQLLQAFKELHFHKCMHRDIKPSNILISQGL-------------IKLGDFGFAKQLN-D---QD
||.||||||| ||.|.          |.| .||...||.|..||||| |...||||||.||||. |              .|..||||||... |   |.
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ITKTAL------GTTITMAPEVFY----QQEYS-YEADMFSLGIVFYYMLFGQYPFKPQGLNPETLFLQIKE-------------QNINFNL--NGVTIS
...|..      || ..|||...     |..|. |..|..|||..||.||.|..||. .  |.. |  ..|.             |...|.   |...||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

RNTQDLIKQMTAYDRKQRITWLGIYQHPAL
 ...|||..|  ||.|.||.|  ...|| .
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 15044.AA Ciliate-E2-Unclassified 18-275 27 3.1e-79 269.56 In-house 1-352 (352) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-352/352
Sequence Identity: 27% (98 aa)

YRIIKTLGKGQYGTVYLAIDSNQQQQF------AVKQIFSQSLINKKLNELLNQELTIQKI----------------IKSQHTVQVIEDFFDQNFKTHII
|.|||..|.|..|.||......|. |.       ..||..| .|..|  |..|........                . ..| . | . . .|. .. .|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IQEYCDGGDLEQYVKKY-----------------KYLPEAQAI-----SYLKQLLQAFKELHFHK-CMHRDIKPSNILISQG----LIKLGDFGFAKQLN
. |||.||||.|| ||.                 | ..| ||.      |..|.||... ||  . . ||||||.|||....     ||. |||..|...
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

D----------------QDITKTALGTTITM----APEVFYQQEYS----YEADMFSLGIVFYYMLFGQYPFKPQGLNP--------------ETLFLQI
.                |....|  || ..|    ||||. .|.|.    |..|..|||...|.||||.|||. .  .               . |. .|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KEQNINFNLNG-----VTISRNTQDLIK----QMTAYDRKQRITWLGIYQHPAL
|..||.|.         ..| . .|.|.    .|  .. ..|||.  | .|| .
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 15044.AA Ciliate-E2 18-275 25 1.5e-78 267.3 In-house 1-365 (365) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-365/365
Sequence Identity: 25% (95 aa)

YRIIKTLGKGQYGTVYLAIDSNQQQQFA-----------------VKQIFSQSLINKKLNELLNQELTIQK----------------IIKSQHTVQVIED
| .|| .|.|..|.||.. . ..|.|||                  ..|.    ..|.  | ..||. | .                .... . .. .| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FFDQNFKTHIIIQEYCDGGDLEQYVK------------KYKYLPEAQAISYLKQLLQ---------------AFKELHFHK-CMHRDIKPSNILISQGLI
| ... ..  .. |||.||||..| |            . ||. | ... . ||.||               |...||  . ..||||||.|||.    |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----I

KLGDFGFAKQLNDQ--------------------------------DITKTALGTTITMAPEVFY---------QQEYSYEADMFSLGIVFYYMLFGQYP
|. |||..|...|.                                ....| .||   ||||..          |..|.|..|..|||...|.||||..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FKPQGLNPETLFLQIKEQNINFNLN---------------GVTISRNTQDLIKQ----MTAYDRKQRIT-WLGIYQHPAL
|          . |||...|.|. .                  .| ...||||.    |  .| ..||| |  | .|| .
F----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 15044.AA S_TKc 18-275 29 4.4e-77 263.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-231/231
Sequence Identity: 29% (82 aa)

YRIIKTLGKGQYGTVYLAIDSNQQQQFAVKQIFSQSLINKKLNELLNQELTIQKIIKSQHTVQVIEDFFDQNFKTHIIIQEYCDG--GDLEQYVKKYKY-
|.|....||| .|.||.... . ....|.|.|           | . .|. | |  .  . |. .. | |   .   .. |||||  ||| .| ||... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LPEAQAISYLKQLLQAFKELHFHKCMHRDIKPSNILISQGLIKLGDFGFAKQLNDQDITKTALGTTITMAPEVFYQQEYSY-EADMFSLGIVFYY
     .|| .| .|..|...| . .| |. .|||.||.|||...  ||..|||.|.||      .|  ||   |||||.    |.. ..|. |.|...| 
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLFGQYPFKPQGLNPETLFLQIKEQNINFNLNGVTISRNTQDLIKQMTAYDRKQRITWLGIYQ-------HPAL
|| |. ||     .....| .|.             |.   |.|...  .| ..|.|   . |       || .
MLCGYPPFP----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15044.AA CAMK 23-275 20 1.3e-66 213.43 In-house 1-425 (425) Show / Hide 
Range on Protein: 23-275
Range on HMM: 1-425/425
Sequence Identity: 20% (89 aa)

TLGKGQYGTVYLAIDSNQQ------------QQFAVKQIFSQSLIN-------------------------KKLNELLNQELTIQKI-------IKSQHT
|||.|..|.|.|.|. | .            |..|.| |  . | .                          |  . . .|. | |        ..  . 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQVIEDFFDQN--------------FKT----HIIIQ---EYCDGG----DLEQYVKKY---------------KYLPEAQAISYLKQLLQAFKELHFHK
.. .| . | .              | |     ...    |||.||    || .|...                ....|..|  | .|...| . .| |.
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

CMHRDIKPSNILISQ------------------GLIKLGDFGFAKQLND------------------------QDITKTALGTTITMA-PEVFYQ-----
 .|||.|| |||...                  . ||. |||||.....                         .  ||  ||   || |||. .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QEYSYEADMFSLGIVFYYMLFGQYPFKPQ-----------GLNPETLFLQIKEQNINFNLNGVT-------------ISRN--------TQ
         . |....|| |.|.. | || | .||              | |.. || .|.. . .|    ..             || .         .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIKQMTAYDRKQRITWLGIYQHPAL
|||..|  .| ..|.|   . .|| .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 15044.AA Pkinase 18-275 29 9.7e-63 219.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

YRIIKTLGKGQYGTVYLAIDSNQQQQFAVKQIFSQSLINKKLNELLN-QELTIQKIIKSQHTVQVIEDFFDQNFKTHII-IQEYCDGG----DLEQYVK-
|.|....|.| .|.||.... . ....|||.|  ..   .|. .... .|. | | ... . |. .. | |   |.||  ..|||.||    ||  |.. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFDYIST

-KYKYL--PEAQAISYLKQLLQAFKELHFHKCMHRDIKPSNILIS-QGLI----KLGDFGFAKQ--LNDQDITKTALGTTITMAPEVFY-QQEYSYEADM
 ... .  .| ....|..|.|.. . .| ....|||.||.||||. .| |    |..|||.|||  .  .  ..|  ||   |||||   .|.|....||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSLGIVFYYMLFGQYPFKPQ----GLNPETLFLQIKEQNINFN-LNGVTIS-----------------RNTQDLIKQMTAYDRKQRITWLGIYQHPAL
.|.|...|.||.|. ||. .    ....  .. .|..  . |.  .  .||                 .. .|.|| . ..| |.|.|.  | ||| .
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 15044.AA CAMKL 18-275 27 2e-53 168.81 In-house 1-297 (297) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-297/297
Sequence Identity: 27% (82 aa)

YRIIKTLGKGQYGTVYLAID-SNQQQQFAVKQIFSQSLI-NKKLNEL-----------LNQELTIQKIIK---SQHTVQVIEDFFDQNF----KTHIIIQ
|||.|||||| .|.| ||.. ...... |.| |  . .  . . .             . .|  |.| ..    .. ..  | . ....    |   .. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCDGGD--LEQYVKKYKY----LPEAQAISYLKQLLQAFKELHFHKCMHRDIKPSNILISQGL---IKLGDFGFAKQLND-----QDITKTALGTTITM
|||.||.  | .|..| ..    .|| .|  | .|.. | . .| |.  |||||| |||...     ||. ||||. .  .      .  ||  |.   |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVFYQ--QEYS-YEADMFSLGIVFYYMLFGQYPFKPQGL------NPETLFLQIKEQNINFNLNGVTISRNTQDLIKQMTAYDRKQRITWLGIYQHPA
|||.|    ..|  ...|. |.|.. | |..|..||. . .      |  .|...|...  ...   . .|   .|||..|   . ..|.|   | .|| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIW-YHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

L
.
M
Kinase 15044.AA Ciliate-E2c 18-275 30 2.6e-52 180.1 In-house 1-310 (310) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-310/310
Sequence Identity: 30% (95 aa)

YRIIKTLGKGQYGTVYLA----IDSNQQQQ------FAVKQIFSQSL----INKKLNE-LLNQELTIQKIIKSQHTVQVIEDFF--DQNFKTHIIIQEYC
. . . ||.|.||.||.|     ..|.. .      ||.| .  ...    || |  .  . .|. ..|  .. | .. . |..  |...    .| |||
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFY-DAKQTDKHI---YLIMEYC

DGGDLEQYVKKYKYLPEAQAISYLKQLLQAFKELHFH-KCMHRDIKPSNILISQGLIKLGDFGFAKQLNDQDITKTA-----LGTTITMAPEVFYQ-QEY
 ||.||||...  .. |.| . | .|...|||.||   .  ||||||.||||  |.||. ||||.|. .|. |. |       || . |||..    ..|
NGGTLEQYIYHKPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYY

SYEADMFSLGIVFYYMLFGQYPFK---------------PQGLN-PETLFLQIK---------------EQNINFNLN-GVTISRNTQDLIKQMTAYDRK
 . .|  |||.. ||||.  .|..               |.  |  . |.  |.                |||.|. |  . ||  ...||. |  .| .
TEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEE

QRITWLGIYQHPAL
 || |  |  |. .
KRIDWDEIFNHECI
Kinase 15044.AA Ciliate-E2a 18-275 31 6e-52 151.22 In-house 1-275 (275) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-275/275
Sequence Identity: 31% (88 aa)

YRIIKTLGKGQYGTVYLAIDSNQQQQFAVKQIFSQSLINKKLNELLNQELTIQKIIKSQHTVQVIEDFFDQNFKTHI-IIQEYCDGGDLEQYVKKYKYLP
|..|| .|||..| ||||   .. .|||.| .     ..|| .| . .|. | . ..  .  . .| . |   .... .. |||.||.|... |. | . 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYED---ENNYYLVMEYCEGGELYDKIKQCKRFF

EA--QAISYLKQLL-QAFKELHFHKCMHRDIKPSNILI----SQG----LIKLGDFGFAKQL--NDQDITKTALGTTITMAPEVFYQQE------YSYEA
|   .. ....||| |..  .|  . ||||.|| |||.    ...     ||. |||.|..   ....  ..  ||   .||||.   |      |..  
EEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKC

DMFSLGIVFYYMLFGQYPFKPQGLNPETLFLQIKEQNINFNLNG--VTISRNTQDLIKQMTAYDRKQRITWLGIYQHPAL
||.|.|..|| .|.|. |||  | . .  . |.|. .|.|| .     .| ...||.|.|  .| |.|||   ...||  
DMWSCGVIFYILLCGKPPFK--GKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 15044.AA STE 18-216 26 1.1e-50 174.69 In-house 1-268 (359) Show / Hide 
Range on Protein: 18-216
Range on HMM: 1-268/359
Sequence Identity: 26% (72 aa)

YRIIKTLGKGQYGTVYLAIDSN---------------QQQQFAVKQI-FSQ-------------SLINKKLNELLNQELTIQKIIK--SQHTVQVIEDFF
...|. .||| .||||.|.. .               ... .|.||. ...             . .|..  . . .|. | |  .  ... |. .  .|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----DQNFKTHIIIQEYCDGGDLEQYVK-KY-------------KYLPEAQAISYLKQLLQA-FKELHFHKCMHRDIKPSNILISQGLIKLGDFGFAKQ
     ..|  .  |. ||.||| |.. .| ||             ...|| | . ...|.|..  . || |. .||||||.|||.    .|| |||...|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

LND-----------------QDITKTALGTTITMAPEVFYQ------QEYSYEADMFSLGIVFYYMLFGQYPF
|.|                 |  ..|  ||   |||||  |      ..|.. .|. |||..   |. |..|.
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase 15044.AA Ciliate-E2b 18-237 27 2.3e-48 145.12 In-house 1-233 (272) Show / Hide 
Range on Protein: 18-237
Range on HMM: 1-233/272
Sequence Identity: 27% (64 aa)

YRIIKTLGKGQYGTVYLAID-SNQQQQFAVKQIFSQSLINKKLNELLNQELTIQKIIKSQHTVQVIEDFFDQNFKTHIIIQEYCDGGDLEQYVKKYK--Y
  .|| ||.||.| |||     |..|..| |.| . ..| . .   . ||  . ....    .. |  | | ..     . |.| |..|. ..   .   
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQH--MYFMMEFCNGMELFDVIREIGRLL

LPEAQAISYLKQLLQAFKELHFHKCMHRDIKPSNILISQ-GLIKLGDFGFAKQLNDQDI----TKTALGTTITMAPEVFY-----QQEYSYEADMFSLGI
| . ..  | .... ....||  . ..|||||.||.. . | .|| |.| || . ..      | |  ||   ||||.       .. |.|..|..|.||
LSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGI

VFYYMLFGQYPFKPQGLNPETLFLQIKEQ--NINF
. | ...|. |.     .|. .  .| ..  .|.|
CLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQF
Kinase 15044.AA TyrKc 18-275 21 1.1e-13 -1.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-275
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YRIIKTLGKGQYGTVYLAIDSNQQQQFAVKQIFSQSLINKKLNELLNQELTIQKII--KSQHTVQVIEDFFDQ--NF---KTHIIIQEYCDGGDLEQYVK
 . .|.|| |..|.||... .   .| ||| . . .       | . .|. | . .  . .. |. .    .|  ||   . . |. ||...||| .| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KYKY-LPEAQAISYLKQLLQAFKELHFHKCMHRDIKPSNILISQGL-IKLGDFGFAKQLNDQ-------DITKTAL--GTT--IT---MAPEVFYQQEYS
|..  |. .. .|.  |  .    || ..| |||.   |.|.. .. .| .||| .. . |        |  ...   |.   .    ||||..   ...
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YEADMFSLGIVFYYML-FGQYPFKP---QGLNPETLFLQIKEQNINFNLNG------VTISRNTQDLIKQMTAYDRKQRITWLGIYQHPAL
 . | .| |.. . .. .|| |      | .... .. ..|. .             |. .    ...||  ..| ..| |   |  |  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 15044.AA Pkinase_Tyr 93-205 25 2e-06 22.4 Pfam 82-203 (270) Show / Hide 
Range on Protein: 93-205
Range on HMM: 82-203/270
Sequence Identity: 25% (31 aa)

HIIIQEYCDGGDLEQYVKKY----KYLPEAQAISYLKQLLQAFKELHFHKCMHRDIKPSNILIS-QGLIKLGDFGFAKQLNDQDIT-KTALGTTIT---M
..|. ||. .|||  | .|     . |.  . ...  |  ..   |. ..| |||.   |.|.. .. .| .||| |. . . |   ... |. .    |
IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM

APEVFYQQEYSYEADMFSLGIV
|||..   ... . |  | |..
APECINYGKFTTKSDVWSFGVL
Kinase 15044.AA Pkinase_Tyr 18-36 36 0.00388 11.25 Pfam 1-19 (270) Show / Hide 
Range on Protein: 18-36
Range on HMM: 1-19/270
Sequence Identity: 36% (7 aa)

YRIIKTLGKGQYGTVYLAI
 ...|.||.|..|.||...
ITFGKKLGEGAFGEVYKGT