Gene 15010 (Tetrahymena)
15010
Sequence
Protein domains of 15010.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 15010.AA | ULK | 55-312 | 34 | 1.4e-125 | 423.47 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-324/324 Sequence Identity: 34% (112 aa) YIFIKQIGSGAYS-TVHQGKHNQT---YQKVAIKMIPNSKLNETIYQ--------RVVSEIKILTRLN---HPN--IVRIIDFKKTS--QNYYLIFEFCS |. ....|.|.. .|..|....| |.||.|||. .|.|. .. .||.|. |. ||| ||. .|...|| |.|.|.|.| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN NGDLENYIKKH-------YEGKISETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEF------------TIKIADFGFAKHNQDD----DLLKS ||||.||||. .....|| ..|.. | ..|||| ||.|.|||.|..|||. . . ..|||||||||| ... ..... GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT TL------GTPITMAPEILN----GKQYN-EKCDIWSLGVIIYQMVFGKPP----FMPAKGGGINGLIRE-------IQKEKFDFP---DQIPISEELKN .. |||..|||.||. .|.|. ||||||||.|.|.|..||.| |.. . . | ||. |......|| ....||.|.|. CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD LLRRMLTVDPQKRLNFKELFSNRWI |.||||..|. .| .. |.|.. |. LIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | 15010.AA | ULK | 55-312 | 35 | 9.5e-124 | 417.42 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-329/329 Sequence Identity: 35% (117 aa) YIFIKQIGSGAYSTVHQGKHNQT----YQKVAIKMIPNSKLNETIYQR--------VVSEIKILTRLN--------HPNIVRIIDFKKTS--QNYYLIFE |. ....|.|.. .|..|....| .|||.|||. .|.|. ... . .||||. .|. |||||. .|...|| |.|.|.| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME FCSNGDLENYIKKH--------YEGKISETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEF------------TIKIADFGFAKHNQDD----D .| ||||.||||. .....|| ..|.. | ..|||| ||.|.|||.|..|||... . ..|||||||||| ..| . YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ LLKSTL------GTPITMAPEILN----GKQYN-EKCDIWSLGVIIYQMVFGKPP----FMPAKGGGINGLIRE-------IQKEKFDFP---DQIPISE ...... |||..|||.||. .|.|. ||||||||.|.|.|..|||| |.. . .|. ||. |.|....|| ....||. MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP ELKNLLRRMLTVDPQKRLNFKELFSNRWI |.|.|.||||..|. .| .. |||.. |. ECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | 15010.AA | S_TKc | 55-312 | 32 | 1.3e-92 | 314.93 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-231/231 Sequence Identity: 32% (89 aa) YIFIKQIGSGAYSTVHQGKHNQTYQKVAIKMIPNSKLNETIYQRVVSEIKILTRLNHPNIVRIIDFKKTSQNYYLIFEFCSN--GDLENYIKKHYEGK-- | ....||.||...|....|. | ..||||.|. ... .||.|| . .|||||...|. . ...|...|.|.. ||| ||||. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --ISETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEFTIKIADFGFAKHNQDDDLLKSTLGTPITMAPEILNGKQYNE-KCDIWSLGVIIYQMV ..| .. .. |. .| . . .|.|.||||| .|||.|| .|||.|||.|.. .. ||| ||||.| .|. |||.||.|.|.| |. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML FGKPPFMPAKGGGINGLIREIQKEKFDFPDQIPISEELKNLLRRMLTVDPQKRLNFKELFS-------NRWI |.||| .. ... | |.|.|...|..|..||.||. |.. |. CGYPPFP-----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 15010.AA | CAMK | 60-312 | 25 | 2e-90 | 291.54 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 60-312 Range on HMM: 1-425/425 Sequence Identity: 25% (108 aa) QIGSGAYSTVHQGKHNQT------------YQKVAIKMIPNSKLN--------------------------ETIYQRVVSEIKILTR-------LNHPNI ..|.|....|. ..| .| ||||||.|. .|| . ..| .||.|. . |.|||| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VRIIDFKK------------TSQN--------YYLIF---EFCSNG----DLENYIKKHYE-------------GKISETLCQQVIFQVREAFKELTKHK ...... | .. .|... |.||.| || .||..| |...| ..... |. .| . . .|. IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN IVHRDLKLANILVDEE-----------------FTIKIADFGFAKHNQD------------------------DDLLKSTLGTPITMA-PEILNGKQ--- |||||||. |||.|. ..|||.|||||.. .. ....| ||| || ||.||||. IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN -----------YNEKCDIWSLGVIIYQMVFGKPPFMPAKGGGING----------LIREIQKEKFDFPDQ----IP----------ISEE--------LK |..|||.||.||| | |. |.||| .. | . | . |.| |.|||. |. ||.| | MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK NLLRRMLTVDPQKRLNFKELFSNRWI .|.|.||.|||.||.. .. . |. DLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 15010.AA | Ciliate-E2 | 55-312 | 26 | 2.9e-90 | 306.16 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-365/365 Sequence Identity: 26% (102 aa) YIFIKQIGSGAYSTVHQGKHNQTYQKVAIKMIPNSK-------------------LNETIYQRVVSEIKILT----------------RLNHPNIVRIID |.|||.||.|....| ..|. .. ...|||.| | ... . . .||.|. .||||||..... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE FKK--TSQNYYLIFEFCSNGDLENYIKKH----------YEGKISETLCQQVIFQVRE---------------AFKELTKHK-IVHRDLKLANILVDEEF . . . .|.||..|.|. |||. |||.. . ....| ..... |. . |...| . . |.|||.|. |||. CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---- TIKIADFGFAKHNQDD--------------------------------DLLKSTLGTPITMAPEILNGKQ---------YNEKCDIWSLGVIIYQMVFGK |||.|||..| ..|| .. ....||| |||||||||. |..||||||||||.|.|.||| -IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK PPFMPAKGGGINGLIREIQKEKFDFP----------------DQIPISEELKNLLRR----MLTVDPQKRLN-FKELFSNRWI ||| ...|.. |.||| . .|.| |.|... || .||.||.. ..... . |. PPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 15010.AA | Pkinase | 55-312 | 30 | 9e-89 | 306.02 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-293/293 Sequence Identity: 30% (91 aa) YIFIKQIGSGAYSTVHQGKHNQTYQKVAIKMIPNSKLNETIYQRVVS--EIKILTRLNHPNIVRIIDFKKTSQNYYLIFEFCSNG----DLENYIKKHYE | ....||||....| ...| | ..||.| |. .. .. |. . ||.|. |||||||||..|. .....|...|.| .| || ||. ... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GKI--SETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEFTI----KIADFGFAKH--NQDDDLLKSTLGTPITMAPEILN-GKQYNEKCDIWSL |.. || |. .. |. .. . . ...|.|||||..|||.|.. .| ||.|||.||. . . ... ||| ||||... |. | |.|.||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVIIYQMVFGKPPFMPA----KGGGINGLIREIQKEKFDFPDQIPIS-------------------EELKNLLRRMLTVDPQKRLNFKELFSNRWI |.|.|.|..|.||| . . . .|..| . ...|. . ..| ||.| .....|..||.||....... |. GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 15010.AA | AGC | 55-312 | 21 | 3e-88 | 227.54 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-395/395 Sequence Identity: 21% (87 aa) YIFIKQIGSGAYSTVHQGKHN------QTYQKVAIKMIPNSK--------LNETIYQR--------VVSEIKILTRLN----------HPNIVR-IIDFK . |.| || |....|.. ... .| . |.|.. .. | .. | .| .||...| ||.||. FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF KTSQN--YYLIFEFCS--------NGDLENYIKKH---YEGKISETLCQQVIFQ-------VREAFKELTK-HKIVHRD-LKLANILVDEEFTIKIADFG .. .. |.. |... |..| .. .. ||. .| .. . . . |. | . ..|.||| ||. ||| ||. ||..||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG FAKHNQDD---------------------------------------------------DLLKSTLG--TPITMAPEILNGKQYNEKCDIWS--LGVIIY ..| . .| |. .. | || |||||| |. ||.|| ||...| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY QMVFGKPPFMPAKGG----------GINGLIRE-----IQKEKF------DFPDQIPISEELKNLLRRMLTVDPQKRLN----------FKELFSNRWI .|..|.||| . . .|.. .|.|| .||.. .|.|.|.|....|..|| ||| ..|. . | EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 15010.AA | CAMKL | 55-312 | 32 | 2.9e-82 | 262.33 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-297/297 Sequence Identity: 32% (98 aa) YIFIKQIGSGAYSTVHQGKH-NQTYQKVAIKMIPNSKLN-ETIYQR------------VVSEIKILTRLN---HPNIVRIIDFKKTSQN------YYLIF |...|..| |....| ..| | .|||||.| .|.. ... .. . ||.|. .|| ||||... . |... .||. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EFCSNGD--LENYIKKHYE--GKISETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEF--TIKIADFGFA---K-H-NQDDDLLKSTLGTPITM | ||.|. | .||.|| . |...| ... |. .| . . .|.|||||.|. |||.|| .|||.||||. . . ......|| |.| | EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEILNG--KQYN-EKCDIWSLGVIIYQMVFGKPPFMPA-----KGGGINGLIREIQKEKFDFPDQIPISEELKNLLRRMLTVDPQKRLNFKELFSNRWI ||||..| |.|. | ||||.||| | ||.|. || . . | | ..| . . .| . .| ....|.|.||.|.| || . ... . .| APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | 15010.AA | Ciliate-E2-Unclassified | 55-312 | 25 | 3.4e-80 | 272.75 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-352/352 Sequence Identity: 25% (91 aa) YIFIKQIGSGAYSTVHQGKHNQTYQKVAIKMIPNSKLNETIYQRV----------VSEIK-------------ILTRLNHPNIVRIIDFKKTSQNYYLIF |..|||||.|....|.. .|....|. |.|.. .. . ... . ..| || ..||.||. .. ... || |.. YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM EFCSNGDLENYIKK---------------HYEGKISETLCQ-----QVIFQVREAFKELTKHK-IVHRDLKLANILVDEE---FTIKIADFGFAKHNQDD |.| .|||..|||| .. ...| .. . . |. .... | . . |.|||.|. |||.|.. . |||.|||..|..|.. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN ----------------DLLKSTLGTPITM----APEILNGKQYN----EKCDIWSLGVIIYQMVFGKPPFMPAKGGG-------------INGLIREIQK ...... |||..| |||.| |..|. .||||||||||.|.|.||..|| . . |...|.. NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ EKFDFPDQIP------ISEELKNLLR----RMLTVDPQKRLNFKELFSNRWI ...|| . . .|.| |.... .|| ..| ||..|.... |. KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 15010.AA | MARK | 55-312 | 39 | 6.1e-77 | 251.07 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-262/262 Sequence Identity: 39% (104 aa) YIFIKQIGSGAYSTVHQGKHNQTYQKVAIKMIPNSKLNE-TIYQRVVSEIKILTRLNHPNIVR---IIDFKKTSQN-YYLIFEFCSNGDLENYIKKHYEG | ..|.|| |.|..| . | | .|||||.... |||. . | .||.|. .|.||||.. .|. . |.|. ||| | .|.|.| .|||.| | YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIE-QDTEQHQIYLIMEYASGGELYDYIKAHPNG KISETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEF--TIKIADFGFAKHNQDDDLLKSTLGTPITMAPEILNGKQYN-EKCDIWSLGVIIYQM ...| .. . |. .| . . .. |||||.|. |||.||. |||.||||. . . . .|.. ||| |||||...| |. | |||||||. | | RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM VFGKPPFMPAKGGGINGLIREIQKEKFDFPDQIPISEELKNLLRRMLTVDPQKRLNFKELFSNRWI | |. ||. ... ... | ..|...|.|.|. .| |..||..|.|||.| .| .|. . .|. VCGYFPFD-GDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | 15010.AA | Ciliate-E2c | 55-312 | 31 | 3.7e-71 | 242.73 | In-house | 1-310 (310) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-310/310 Sequence Identity: 31% (100 aa) YIFIKQIGSGAYSTVHQGKHNQ---TYQKV-------AIKMIPNSKL-----NETIYQ-RVVSEIKILTRLNHPNIVRIIDFKKTSQNYYLIFEFCSNGD . . ||| | .| .. . . ... ||||.. . . ||.. .. || .. .|||.|....|.|.|... ||| |.|. |. IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT LENYIKKH-YEGKISETLCQQVIF---QVREAFKELTKH-KIVHRDLKLANILVDEEFTIKIADFGFAKHNQDDDLLKST-----LGTPITMAPEILNG- || ||.. . ..| .|... | |||.| | .| |||.| .||| . .||||||||.| ||| . |||. |||.||.| LEQYIYHKPK---PNE---KQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNG-MIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGK KQYNEKCDIWSLGVIIYQMVFGKPPFM---------------PAKGGGINGLIREIQ---------------KEKFDFPDQ--IPISEELKNLLRRMLTV ..| || ||||||| |.|.. |.|. | ... .|. .| . .. ||.. . ||.|.| |...|| | NYYTEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQV DPQKRLNFKELFSNRWI |. ||....|.| . | DEEKRIDWDEIFNHECI |
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Kinase | 15010.AA | QIK | 55-312 | 34 | 2.6e-63 | 216.64 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 55-312 Range on HMM: 1-272/272 Sequence Identity: 34% (95 aa) YIFIKQIGSGAYSTVHQGKHNQTYQKVAIKMIPNSKLNETIYQRVVSEIKILTRLNHPNIVRIIDFKKTSQNYYLIFEFCSNGDLENYIKKHYEGK---- | . || | . .| ..| | .||||| | |.|.|. |... |..|. .|.||.|.. . | . |.. |.||||.. |. || |. YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKH--GRKGVK ----------------ISETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEFTIKIADFGFAKHNQDDDLLKSTLGTPITMAPEILNGKQYN-EK ..| ... |. | . . |..||||||| ||| |.. |||||||| . . . ||.. |.| |||.. ||.|. | MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK CDIWSLGVIIYQMVFGKPPFMPAKGGGINGLIREIQKEKFDFPDQIPISEELKNLLRRMLTVDPQKRLNFKELFSNRWI ||||.||. | .| |. || | .. | . . || | .|... | |.||.|||..|.. . ||. VDIWSMGVVLYVLVCGALPFD---GKTLQNLRQRVLSGKFRIP--FFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM |
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Kinase | 15010.AA | Pkinase_Tyr | 55-241 | 30 | 7.1e-36 | 122.13 | Pfam | 1-202 (270) | Show / Hide |
Range on Protein: 55-241 Range on HMM: 1-202/270 Sequence Identity: 30% (61 aa) YIFIKQIGSGAYSTVHQGKHN----QTYQKVAIKMIPNSKLNETI--YQRVVSEIKILTRL-NHPNIVRIIDFKK-TSQN--YYLIFEFCSNGDLENYIK .|.|..|.||. .|..|. . .| ..||.||. . . . . .|.||.. | .|||||| . .. .|...|.. .||| .| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR KH--YEGKISETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEFTIKIADFGFAKHNQDDDLL-KSTLGTPIT---MAPEILNGKQYNEKCDIWS || ..... | .|. .. | ....|||| |.||.|....||.||| |. ..|| ... |... |||| .| . ...| |.|| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS LGV || FGV |
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Kinase | 15010.AA | TyrKc | 55-311 | 22 | 3.2e-32 | 114.28 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 55-311 Range on HMM: 1-280/280 Sequence Identity: 22% (67 aa) YIFIKQIGSGAYSTVHQGKHNQTYQKVAIKMIPNSKLNETIYQRVVSEIKILTRL--NHPNIVRIIDFKKTS-------QNYYLIFEFCSNGDLENYIKK ..|..|.||. .|..|. . ..||.||. ... . .|..|...| .||||||.. .. . .....|....||| .|..| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK HYEGKISETLCQQVIFQVREAFKELTKHKIVHRDLKLANILVDEEFTIKIADFGFAKHNQDD-------DLLKSTL--GTP--IT---MAPEILNGKQYN | . .. . .|. . | .....|||| |.||.|..|.||.||| .. || | ... |. . |||| .| . .. HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT EKCDIWSLGVIIYQMV-FGKPPF-------MPAKGGGINGLIREIQKEKFDFPDQIP-------ISEELKNLLRRMLTVDPQKRLNFKELFSNRW .| |.|| || .. . .|..| |... .|. ... . . . . ..|. .. .. || .| .|.|. .. TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQ-----EVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |