Gene 9404 (Tetrahymena)

9404

Species: Tetrahymena
Alias: 9.m00425, 3699.m00133, TTHERM_00128400, 541, 9404, PreTt09404
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
9404.AA Protein None 350 None Fasta, JSON
9404.kin_dom Protein Kinase Domain None 108 None Fasta, JSON
9404.NA RNA None 1053 None Fasta, JSON

Protein domain

Protein domains of 9404.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 9404.AA Other-Unique 72-172 9 1.7e-10 32.41 In-house 1-158 (249) Show / Hide 
Range on Protein: 72-172
Range on HMM: 1-158/249
Sequence Identity: 9% (15 aa)

IIKYYDYHFDDVKKELLVLREYSRKTLDFALQSRRARKNDFK---------------------------------------------------KQELLDF
|....  ....|.| . ........   . .   .....|..                                                    .|....
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWMN

TAQILKVLTHLEENGVILLNLKPTNIFTNEEITYKVGG--------LARSDNNIWLNSEY
. .....|.||..|. |. ...|.||. |......  .        . .....|......
CCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTII-IEHQHIKIMDFN
Kinase 9404.AA Ciliate-A5 169-246 26 2.7e-09 28.48 In-house 169-246 (275) Show / Hide 
Range on Protein: 169-246
Range on HMM: 169-246/275
Sequence Identity: 26% (21 aa)

NSEYLSPELKEDFEKNPSKLPHHLNKNYSKKKAAVYTLGMILLEAATLEDISNVNSIGSSLLQSKK--LKQLLDLVEEKY
|. ||||.. . .. ..  .    .... . |  |..||||.|| .|..|.. ..   ...   .   .|||....|.||
NKQYLSPMQWYQMMHRD--EQNIQRPEHNWYKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKY
S_TKc 9404.AA S_TKc 22-279 16 1e-06 -78.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-279
Range on HMM: 1-231/231
Sequence Identity: 16% (48 aa)

FED-------AMSQYYQSPDNP--EVILERIFIESEEELFYLFNEYNAVVNGQLFKMKNIIKYYDYHFDDVKKELLVLREYSRK---TLDFALQSRRARK
.|        |... |.  ..   ..    |          . .| .   .    . .||.|.||.  |   ..| .  ||      .|   ...|. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

ND--FKKQELLDFTAQILKVLTHLEENGVILLNLKPTNIFTNEEITYKVG--GLARSDNNIWLNS-----EYLSPELKEDFEKNPSKLPHHLNKNYSKKK
..  |   .   ...||.. | .. ..|.|   ||| ||. .|  . |..  ||||       ..     .|..||.                  |.|.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----------------GYGKCK

AAVYTLGMILLEAAT----LEDISNVNSIGSSLLQSKKLKQLLDLVEEKYQGYRLFLERFFL-PYSQRPDIVECWCMSSD---LQII
. .. .| || | ..     .                 ........    .  . |... .    ..|| . |.  . .|    . .
CDWWSCGCILYEMLCGYPPFP----------------QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 9404.AA Ciliate-E1 37-155 21 2e-06 17.68 In-house 24-149 (202) Show / Hide 
Range on Protein: 37-155
Range on HMM: 24-149/202
Sequence Identity: 21% (27 aa)

EVILERIFIESEEELFYLFNEYNAVVNGQLFKMKNIIKYYDYHFDDVKKELLVLREYSRKTLDFALQ---------SRRARKNDFKKQELLDFTAQILKV
..| ...|....... .. .||. . .  . | ..||...|| ..|  .  . . |.  ..|   ||         . .  .|.|. |...  . |... 
QKIINCCFNYNQNHFQDEIKEYYKIMK--FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDG

LTHLEENGVILLNLKPTNIFTNEEITYK
|  |. ...| ...||.||  | .  |.
LIELHQYNIIHRDIKPQNILINNQGNYV
Kinase 9404.AA Ciliate-C6 174-224 39 7.2e-05 13.2 In-house 207-257 (306) Show / Hide 
Range on Protein: 174-224
Range on HMM: 207-257/306
Sequence Identity: 39% (20 aa)

SPELKEDFEKNPSKLPHHLNKNYSKKKAAVYTLGMILLEAATLEDISNVNS
||||.|  ...  .     |.     |  .  ||||||   ||.||| ||.
SPELREMKKQYNQHQDDNSNQQIDYFKCDIFSLGMILLYMLTLSDISQVNC
Kinase 9404.AA PLK1 70-157 27 0.000358 9.32 In-house 59-141 (253) Show / Hide 
Range on Protein: 70-157
Range on HMM: 59-141/253
Sequence Identity: 27% (24 aa)

KNIIKYYDYHFDDVKKELLVLREYSRKTLDFALQSRRARKNDFKKQELLDFTAQILKVLTHLEENGVILLNLKPTNIFTNEEITYKVG
..|.|.... |.| .   .||   .|. | . |. ||        .|   .. ||..   .|..| .|   ||  |.| |...  |.|
RHIVKFHHF-FEDKQNVYIVLELCRRRSL-MELHKRRKA---ITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIG
Kinase 9404.AA WEE 98-218 18 0.000555 9.33 In-house 93-234 (297) Show / Hide 
Range on Protein: 98-218
Range on HMM: 93-234/297
Sequence Identity: 18% (29 aa)

LDFALQSRRARKND-FKKQELLDFTAQILKVLTHLEEN-GVILLNLKPTNIFTNEE--------------------ITYKVG--GLARSDN----NIWL-
|. ....  ...|. .  ... ..  .|.. | |. .| | . . .|| ||| ...                    ...| |  |.. . |    |    
LLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTDMNSNNNNPHQE

---NSEYLSPELKEDFEKNPSKLPHHLNKNYSKK-KAAVYTLGMILLEAATLED
   .|.|..||.  .            ...|..  || .. ||. ..|.|. .|
QEGDSRYMAPEILQG------------YYHYTHLYKADIFSLGITIYELACNMD
Kinase 9404.AA Ciliate-E6 100-147 18 0.000756 8.54 In-house 37-85 (154) Show / Hide 
Range on Protein: 100-147
Range on HMM: 37-85/154
Sequence Identity: 18% (9 aa)

FALQSRRARKNDFKKQ-ELLDFTAQILKVLTHLEENGVILLNLKPTNIF
....     | ...    ...|..|..... .|  .. .| |... |||
QDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIF