Gene 9187 (Tetrahymena)
9187
Group:
Other
Family:
Ciliate-B3
Sequence
Protein domains of 9187.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 9187.AA | Ciliate-B3 | 98-165 | 56 | 2.7e-33 | 115.11 | In-house | 1-69 (69) | Show / Hide |
Range on Protein: 98-165 Range on HMM: 1-69/69 Sequence Identity: 56% (39 aa) FALYHFTQVASSIRKLHSLNLCHCDIKVDHILIEQQSN-GLKDILIDFKHCQKIKQNQLSQTVCGTLSY |||.||.|| |..||..|.|||||||| ||..||.. ..|.|.||| |||. .|| |. .||||.| FALKHFHQVVEKIKILHEKNICHCDIKVDNILVNQQDKENYKVIIIDFGHCQRKCQNCKSEMICGTLTY |
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Kinase | 9187.AA | Ciliate-C8 | 105-196 | 23 | 1.4e-10 | 34.42 | In-house | 127-238 (238) | Show / Hide |
Range on Protein: 105-196 Range on HMM: 127-238/238 Sequence Identity: 23% (26 aa) QVASSIRKLHSLNLCHCDIKVDHIL-IEQQSNGLKDILID------FKHCQKIKQNQL---------SQTV-----CGTLSYNPLELNDGIAKSQVKPYS |. |. || | | ||| . .| ...|.... | | | ....|. .... ||.. | . |. ... . | . .| QMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFS PYKLDLYQLGMLL | |.|..| .| -KKSDSYSVGLVL |
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Kinase | 9187.AA | C8 | 105-196 | 26 | 2.5e-08 | 25.12 | In-house | 131-226 (226) | Show / Hide |
Range on Protein: 105-196 Range on HMM: 131-226/226 Sequence Identity: 26% (26 aa) QVASSIRKLHSLNLCHCDIKVDHILIEQQSNGL-KDILIDFKHCQKIKQNQ---LSQTV--CGTLSYNPLELNDGIAKSQVKPYSPYKLDLYQLGMLL |. .. .|. | | ||| . .|. . | . . | || ....|. .|. . |||. | | . . |.| |. . ||...|..| QMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKK-QDNQYKQYR-IQSDLFSVGLVL |
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S_TKc | 9187.AA | S_TKc | 5-267 | 13 | 1.7e-07 | -67.01 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 5-267 Range on HMM: 1-231/231 Sequence Identity: 13% (41 aa) FIIH----SGQSADCKVGTLNN--KVYFFKEFFSKKDYNHQKTIYQHLNEITNEVDLSI---------LKMIKYDDHKCQIVFPYIIF---SLTQICSKV . |. .| . .. .. .. ... |. . | .|... . .. .. .|. |. .| .. | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKKHHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKR KSNNT-RGMRWIFALYHFTQVASSIRKLHSLNLCHCDIKVDHILIEQQSNGLKDILIDFKHCQKIKQNQLSQTVCGTLSYNPLELNDGIAKSQVKPYSPY ... . ... | . . |... . .||.. .|.|.| . ||. . ..|| . .. |.|||. | . |. .|.. GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---------GYGKC KLDLYQLGMLLLTLIV---YFRISENMKNLISLKKKNKFLEGITLLYKANYNTNLEIKPEVYDLIWGLLTGEIE---DAAQIFN-------HQVY | | . .| .| ... |. .|. .. . . ||. |.| ..|. . | | .... |. KCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 9187.AA | Ciliate-E1 | 7-190 | 21 | 9.1e-07 | 18.55 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 7-190 Range on HMM: 1-202/202 Sequence Identity: 21% (44 aa) IHSGQSADCKVG--TLNN-----KVYFFKEFF-SKKDYNHQKTIYQ-HLNEITNEVDLSILKMIKYDDH-KCQIVFPYIIFSLTQICS------KVKSNN | .| ... . . || .. . .|. .. ... .. |. .. .... . |...|| |. | |.| . ||.. . .... . IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ TRGMRWIFA--LYHFTQVASSIRKLHSLNLCHCDIKVDHILIEQQSNGLKDILIDFKHCQ--KIKQNQLSQTVCGTLSYNPLEL---NDGIAKSQVKPYS . . | .. . | . ||..|..|.||| . |||..|.|... || .. | .||| .| . | .| | | .. . . .... QNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC---DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKIN PYKLDLY ||.|.| -YKSDIY |
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Kinase | 9187.AA | MELK | 103-203 | 30 | 1e-06 | 18.4 | In-house | 103-197 (254) | Show / Hide |
Range on Protein: 103-203 Range on HMM: 103-197/254 Sequence Identity: 30% (32 aa) FTQVASSIRKLHSLNLCHCDIKVDHILIEQQSNGLKDILIDFKHCQKIKQNQLSQ---TVCGTLSYNPLELNDGIAKSQVKPYSPYKLDLYQLGMLLLTL | |. |.| .|| | |.| . .|.... .. |||| | | | .. | || . | || .| | | |.. .|.|| .| FRQIVSAIAYVHSQGYAHRDLKPENLLFDED---HHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQG------KQYIGSEADVWSMGILLYVL IVYF .. | MCGF |
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Kinase | 9187.AA | Ciliate-E2-Unclassified | 99-200 | 24 | 2e-06 | 18.67 | In-house | 140-264 (352) | Show / Hide |
Range on Protein: 99-200 Range on HMM: 140-264/352 Sequence Identity: 24% (32 aa) AL-----YHFTQVASSIRKLHSLN-LCHCDIKVDHILIEQQSNGLKDILIDFKHCQKIKQN----------------QLSQTVCGTLSYNP------LEL |. . | |. . . .||. | .| ||| . ||. .. . .. .||| . |..|| |...|.|||..| | . AKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQ NDGIAKSQVKPYSPYKLDLYQLGMLLLTLI . . .| || | . ||..| .. GQNYDHSKA-----YKCDIWSLGVILYEML |
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Kinase | 9187.AA | Other-Unique | 98-245 | 6 | 4e-06 | 17.46 | In-house | 1-249 (249) | Show / Hide |
Range on Protein: 98-245 Range on HMM: 1-249/249 Sequence Identity: 6% (17 aa) FALYHFTQVASSIRKLHSLNLCHCDIKVDHILIEQQSNG-------------------------------------------------------LKDILI ..... . ... ..| .. ..|..|..|..| .. .. ...... IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWMN DFKHCQKIKQNQLSQTVCGTLSYNPLELNDG--------------------------------------------IAKSQVKPYSPYKLDLYQLGMLLLT ............ .. ... .. | . .|.. . ...... . |.|.|..|..... CCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNNNMMYFAPEFSCRWCSPETFDYWPLGEKIDQYHFGCYHFH LI------VYFRISENMKNLISLKKKNKFLEGITLLYKANYNTNLEIKPEVYD .. |.. . .....|.|.. | . ... . .|.. .|.. . MNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY |
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Kinase | 9187.AA | CAMK | 103-165 | 20 | 2.5e-05 | 12.34 | In-house | 185-285 (425) | Show / Hide |
Range on Protein: 103-165 Range on HMM: 185-285/425 Sequence Identity: 20% (21 aa) FTQVASSIRKLHSLNLCHCDIKVDHILIEQQSNG--------------LKDILIDFKHCQKIKQ------------------------NQLSQTVCGTLS | |..| .. .||.| .|.|.| . ||. . ... . .||| .|... .|. .|.|||.. FRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPE Y | Y |
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Kinase | 9187.AA | GIN4 | 99-200 | 28 | 8.7e-05 | 10.75 | In-house | 136-229 (293) | Show / Hide |
Range on Protein: 99-200 Range on HMM: 136-229/293 Sequence Identity: 28% (29 aa) ALYHFTQVASSIRKLHSLNLCHCDIKVDHILIEQQSNGLKDILIDFKHCQKIKQNQLSQTVCGTLSYNPLELNDGIAKSQVKPYSPYKLDLYQLGMLLLT |. | |. . |..|.|| |.| . .|.... | .| . || .|.| .| || | |. || || . | . |..| AIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIK--IADFGMAALETDNKLLETSCGSPHYAAPEIVMGI------PYHGFASDVWSCGVILFA LI |. LL |
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Kinase | 9187.AA | MARK | 103-165 | 39 | 0.000111 | 11.42 | In-house | 110-171 (262) | Show / Hide |
Range on Protein: 103-165 Range on HMM: 110-171/262 Sequence Identity: 39% (25 aa) FTQVASSIRKLHSLNLCHCDIKVDHILIEQQSN-GLKDILIDFKHCQKIKQNQLSQTVCGTLSY |.|. | . .|| | .|.||| . ||| .. | | .||| . .|. .|. | |||..| FRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIK--IIDFGFSICIPPGQKLNTFCGTPPY |