Gene 8550 (Tetrahymena)
8550
Sequence
Protein domains of 8550.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 8550.AA | Ciliate-C6 | 135-158 | 57 | 3.4e-09 | 28.72 | In-house | 156-181 (306) | Show / Hide |
Range on Protein: 135-158 Range on HMM: 156-181/306 Sequence Identity: 57% (15 aa) NFQHKDIKPSNIVIKNG--HYYLTDF |. | ||||||| |... |||.|| NIAHRDIKPSNILIMDDENNYYLSDF |
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Kinase | 8550.AA | Ciliate-E1 | 24-188 | 16 | 9.7e-08 | 21.75 | In-house | 2-202 (202) | Show / Hide |
Range on Protein: 24-188 Range on HMM: 2-202/202 Sequence Identity: 16% (34 aa) GQGGFKNVYECVNTQKQQNLIVKISMGDGNADLKNEHANSLKIQFKPLKLAKIDELHSLEFNGE-EYLVGISEIVGE--KNLGMVIE------------- |.|.| |.. .. . ..| . .. .. .|. . .| ..|..|. | . .. . . ... .. .|. . ..| .. GNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQ SKEKPTLANAIKMLIDILFGAFECQISNFQHKDIKPSNIVIKN-GHYYLTDFSSQD-----------ETNIITNSFSPQDYN--------TKNVIQRFDI . . | . ... .....| | .. |. | ||||.||.|.| | | ..||. . ... ... .|. || .... . || NQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDI F . Y |
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Kinase | 8550.AA | Ciliate-B2 | 118-158 | 35 | 2e-06 | 11.03 | In-house | 107-148 (197) | Show / Hide |
Range on Protein: 118-158 Range on HMM: 107-148/197 Sequence Identity: 35% (15 aa) IKMLIDILFGAFECQISNFQHKDIKPSNIVI-KNGHYYLTDF ..| . . | . . | | ||||.|| . .|| | ..|| YQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDF |
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Kinase | 8550.AA | Ciliate-E2b | 138-158 | 40 | 3.4e-05 | 11.92 | In-house | 125-146 (272) | Show / Hide |
Range on Protein: 138-158 Range on HMM: 125-146/272 Sequence Identity: 40% (9 aa) HKDIKPSNIVIKN-GHYYLTDF . ||||.|| . . |. .| |. YRDIKPENIMVDHKGYMKLIDM |
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Kinase | 8550.AA | S_TKc | 17-335 | 13 | 6.3e-05 | -104.69 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 17-335 Range on HMM: 1-231/231 Sequence Identity: 13% (46 aa) LEIVTLKGQGGFKNVYECVNTQKQQNLIVKISMGDGNADLKNEHANSLKIQFKPLKLAKIDELHSLEFNGEEYLVGISEIVGE--KNLGMVIESKEKP-- ||. . |.|.| || |... .. .|| ....| . | . | |. . ..| . | .. .| .|... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK------HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ----TLANAIKMLIDILFGAFECQISNFQHKDIKPSNIVIKNGHYYLTDF--SSQDETNIITNSFSPQDYNTKNVIQRFDIFSLGQTCNLYIKVIMQMNK . | ... |. . | .. | |.||.|| . . | ..|| . | RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------------------------------------------- KEQVVFQTLISYINPICQIITTIKAYISILCFIEKNDLIQSYYG-----------LFIILEIAEFYFEKNNYNDCNEYLKKLECLENDEFDEEKFILYIS .. | |.. . .| . |.. | . |. . .. .||. ----------------TTFCGTP-WYMAPEVL--------GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG----------------- IGYYKLLFFLKYSQNSENCLEYLEKAIQL-------AQKLEQ------THPLK |. ... ..| | | .. | || ---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 8550.AA | MOK | 138-160 | 56 | 0.000157 | 9.55 | In-house | 123-145 (283) | Show / Hide |
Range on Protein: 138-160 Range on HMM: 123-145/283 Sequence Identity: 56% (13 aa) HKDIKPSNIVIKNGHYYLTDFSS |.|.|| ||.||. | |.|| | HRDVKPENILIKQDHLKLADFGS |
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Kinase | 8550.AA | CK1-Unclassified | 17-47 | 29 | 0.000515 | 7.76 | In-house | 1-31 (244) | Show / Hide |
Range on Protein: 17-47 Range on HMM: 1-31/244 Sequence Identity: 29% (9 aa) LEIVTLKGQGGFKNVYECVNTQKQQNLIVKI ... ||| | ..|.|.|.| ... .|. YRVIEKIGQGSFGEIYKCINMQTNEEVAIKL |
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Kinase | 8550.AA | Ciliate-E2 | 135-158 | 41 | 0.001345 | 8.2 | In-house | 181-200 (365) | Show / Hide |
Range on Protein: 135-158 Range on HMM: 181-200/365 Sequence Identity: 41% (10 aa) NFQHKDIKPSNIVIKNGHYYLTDF | | ||||.||.. ..|| NIIHRDIKPENILF----IKIIDF |
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Kinase | 8550.AA | Ciliate-E2 | 17-46 | 31 | 0.005354 | 6.11 | In-house | 1-32 (365) | Show / Hide |
Range on Protein: 17-46 Range on HMM: 1-32/365 Sequence Identity: 31% (10 aa) LEIVTLKGQGGFKNVYEC--VNTQKQQNLIVK ... . |||.| ||.| ..|||...... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKII |