Gene 4546 (Tetrahymena)

4546

Species: Tetrahymena
Alias: 265.m00026, PreTt04546, TTHERM_01179770, 958, 4546
External Links: Tetrahymena Genome Database (TGD) ,
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
4546.AA Protein None 163 None Fasta, JSON
4546.kin_dom Protein Kinase Domain None 51 None Fasta, JSON
4546.NA RNA None 492 None Fasta, JSON

Protein domain

Protein domains of 4546.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 4546.AA CK1-Unclassified 9-77 45 1.4e-34 99.48 In-house 1-71 (244) Show / Hide 
Range on Protein: 9-77
Range on HMM: 1-71/244
Sequence Identity: 45% (33 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDE---TIIDKGIPQVRIFS
.....|.|.|.||||....|...| |||||||  |.|||||.||.|..|||  ..    .| |||| .  ..
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFI-KGIPKMYWCG
Kinase 4546.AA CK1 9-76 42 4.4e-30 100.84 In-house 1-71 (271) Show / Hide 
Range on Protein: 9-76
Range on HMM: 1-71/271
Sequence Identity: 42% (31 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVE--VAIKLEPVNTKHPQLFYEVKLYQYLLQDETIID---KGIPQVRIF
....||.|.|.||.|..| |..|..|  ||||||. ..||||| ||.|.|..|  .  . |   .|||... .
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGH-NC-DNQCHGIPHMYWC
Kinase 4546.AA CK1-D 9-59 54 7.5e-23 77.33 In-house 1-51 (261) Show / Hide 
Range on Protein: 9-59
Range on HMM: 1-51/261
Sequence Identity: 54% (28 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYL
... ||.|||.||.|.|| |...| |||||||.. |||||| .| |.|...
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMM
Kinase 4546.AA CK1-G 9-73 43 7.9e-19 60.37 In-house 1-61 (266) Show / Hide 
Range on Protein: 9-73
Range on HMM: 1-61/266
Sequence Identity: 43% (28 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYLLQDETIIDKGIPQV
..  .| | | |||.| | |. ||. ||||.||. .. |||  | . |. | .       |||||
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCP----EGIPQV
Kinase 4546.AA CK1-A 9-59 52 1.1e-18 62.45 In-house 1-51 (261) Show / Hide 
Range on Protein: 9-59
Range on HMM: 1-51/261
Sequence Identity: 52% (27 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFYEVKLYQYL
..| ||.|||.||.|. |.|..|  |||||.|  . .|||| || |.|. |
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRIL
Kinase 4546.AA CK1 9-61 33 2.7e-18 60.46 In-house 1-66 (339) Show / Hide 
Range on Protein: 9-61
Range on HMM: 1-66/339
Sequence Identity: 33% (22 aa)

FKLTRKLGSGAFG-EIFHG-----VNLKNN-----VEVAIKLEPVNTK--HPQLFYEVKLYQYLLQ
.|...|.|.|.|| .|...     ...|||      |.|.|.||....  |||| .|...|..| .
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQG
Kinase 4546.AA TTBK 9-45 36 8.5e-11 34.42 In-house 1-38 (257) Show / Hide 
Range on Protein: 9-45
Range on HMM: 1-38/257
Sequence Identity: 36% (14 aa)

FKLTRKLGSGAFGEIFHGVNLKNN-VEVAIKLEPVNTK
 | ..| | |.||||. . .. |.  .||||.| ....
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQP
Kinase 4546.AA Ciliate-A9 9-38 28 2.6e-10 19.89 In-house 1-32 (392) Show / Hide 
Range on Protein: 9-38
Range on HMM: 1-32/392
Sequence Identity: 28% (9 aa)

FKLTRKLGSGAFGEIFHGVNLK--NNVEVAIK
|..  ..|.||||  . .  ..  .. |.|.|
FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVK
Kinase 4546.AA TTBKL 9-45 24 3.3e-10 30.73 In-house 1-37 (288) Show / Hide 
Range on Protein: 9-45
Range on HMM: 1-37/288
Sequence Identity: 24% (9 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTK
.. ....|.|.||...|....|.  ..|.. |..|..
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRL
Kinase 4546.AA Src 9-38 50 7.6e-10 29.59 In-house 1-29 (255) Show / Hide 
Range on Protein: 9-38
Range on HMM: 1-29/255
Sequence Identity: 50% (15 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIK
.|| ||||.| ||| . |.  ..|..||.|
IKLCRKLGQGQFGEVWMGY-WNGNTKVAVK
Kinase 4546.AA Pkinase 9-59 21 1.9e-07 27.42 Pfam 1-57 (293) Show / Hide 
Range on Protein: 9-59
Range on HMM: 1-57/293
Sequence Identity: 21% (12 aa)

FKLTRKLGSGAFGEIFHGVNLKNNVEVAIKLEPVNTKHPQLFY------EVKLYQYL
... ||.|||.||. ..... ... .||.|  .. .....  .      |... . |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL
Kinase 4546.AA Pkinase_Tyr 9-38 35 2e-07 25.75 Pfam 1-34 (270) Show / Hide 
Range on Protein: 9-38
Range on HMM: 1-34/270
Sequence Identity: 35% (12 aa)

FKLTRKLGSGAFGEIFHGVNL----KNNVEVAIK
 .. .|||.|||||...|.      .....||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK