Gene 15034 (Tetrahymena)

15034

Species: Tetrahymena
Alias: 1133, PreTt15034, 15034, 71.m00161, 3729.m00039, TTHERM_00545840
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-Unique

Sequence

Name Sequence Type Origin Length Description Download
15034.AA Protein None 331 None Fasta, JSON
15034.kin_dom Protein Kinase Domain None 138 None Fasta, JSON
15034.NA RNA None 996 None Fasta, JSON

Protein domain

Protein domains of 15034.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15034.AA Ciliate-E2 224-330 18 2.4e-17 56.06 In-house 1-184 (365) Show / Hide 
Range on Protein: 224-330
Range on HMM: 1-184/365
Sequence Identity: 18% (35 aa)

YNKNNQQGSNQFYQVRQA----------------------------------KMKDTSRQNKVLNEIEILQ----------------RIKGPSIQNIIEV
|..... |. .| .|...                                  |..  .  . ...|| |..                ... | | ...|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FHEKDNKSLYIVSEYSEGRTLKEELA------------DEQPFEEILILHIIQKILS---------------AVAYLHDKR-ILH
| |||....|.| || .| .|.. .             | ..| |  |..|...||.               |. ||| |  |.|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIH
Kinase 15034.AA CAMK-Unique 248-331 23 4.2e-17 52.82 In-house 59-181 (363) Show / Hide 
Range on Protein: 248-331
Range on HMM: 59-181/363
Sequence Identity: 23% (30 aa)

RQNKVLNEIEILQRIKGPSIQNIIEVFHE-----KDNK---------------SLYIVSEYSEGRTLKEELAD--------------------EQPFEE-
| .|  .|..|... . |   |||....       | |                .||| || .|..|......                    ...|.| 
RDMKLKREHQIWKMVDHP---NIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSER

-ILILHIIQKILSAVAYLHDKRILHG
  ... |.|..||||||.|.. | |.
CWDTCFIMQCLLSAVAYMHSQDIVHR
Kinase 15034.AA Ciliate-E2a 249-330 31 5e-17 46.68 In-house 43-125 (275) Show / Hide 
Range on Protein: 249-330
Range on HMM: 43-125/275
Sequence Identity: 31% (27 aa)

QNKVLNEIEILQRIKGPSIQNIIEVFHEKDNKSLYIVSEYSEGRTLKEELADEQ-PFEE-ILILHIIQKILS-AVAYLHDKRILH
. .. ||| |..... | |  ..||.  .|....|.| || ||..|....   .  |||   | .|.|..|. ...|.| . |.|
KEYFMNEINIMRQLDHPNIIKLYEVY--EDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMH
Kinase 15034.AA CAMK 235-330 18 2.6e-15 45.09 In-house 56-202 (425) Show / Hide 
Range on Protein: 235-330
Range on HMM: 56-202/425
Sequence Identity: 18% (28 aa)

FYQVRQAKMKD------TSRQNKVLNEIEILQR-------IKGPSIQNIIEVFHEKD-----------------NKSLYIVS---EYSEGRTL-------
. ...  | |.       . . .|..||||...       .. | | ...||.  ..                 .| .|.|    || .|  |       
Y-KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDY

---KEE----------LADEQPFEEILILHIIQKILSAVAYLHDKRILH
   ..           . ..  |.|    .... |.|||.|.|.. | |
IVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVH
Kinase 15034.AA Other-Unique 195-330 8 4.3e-14 44.74 In-house 1-210 (249) Show / Hide 
Range on Protein: 195-330
Range on HMM: 1-210/249
Sequence Identity: 8% (19 aa)

KKKKNNNSSSPNMGNLSISKNPNRNNLSQYNKNNQQGSN-------------------------------------------------------------
 |. ......  .......|...... ....|  .. ..                                                             
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWMN

--------QFYQVRQAKMKDTSRQNKVLNEIEILQRIKG---------PSIQNIIEVFHEKDNKSLYIVSEYSEGRTLKEELADEQPFEEILILHIIQKI
        .... ......| . .|...|.. |..  ..         . ....|. |... | ..|. .|. ..|.  .|  | .|..|.. .. ....
CCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFGCY

LSAVAYLHDKRILH
.... ..|.. . |
HFHMNCQHWIFHYH
Kinase 15034.AA Pkinase 237-330 23 3.7e-13 47.59 Pfam 31-131 (293) Show / Hide 
Range on Protein: 237-330
Range on HMM: 31-131/293
Sequence Identity: 23% (24 aa)

QVRQAKMKDTSRQNKVL-NEIEILQRIKGPSIQNIIEVFHEKDNKSLYIVSEYSEGR----TLKEELA--DEQPF--EEILILHIIQKILSAVAYLHDKR
...  . |.  .|.... .||.|..|.. | |  ....|..  ....|.| || ||      |.. .   .. .|  .|  . ...  ||....|.|...
IIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMG

ILH
|.|
IIH
Kinase 15034.AA Ciliate-E2-Unclassified 224-330 17 9.1e-13 40.64 In-house 1-167 (352) Show / Hide 
Range on Protein: 224-330
Range on HMM: 1-167/352
Sequence Identity: 17% (30 aa)

YNKNNQQGSNQFYQVRQAKMKDT----------SRQNKV----------LNEIEILQRIKGPSIQN------------------IIEVFHEKDNKSLYIV
|... | |. .| .|.... |..          . |..           .||.......|. ..|.                  . ......| . .|||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

SEYSEGRTLKEELADE-----------------QPFEEILIL-----HIIQKILSAVAYLHDK-RILH
 || || .|.. . .                  . |.|  ..     ...  ||..  ||| |  |.|
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIH
Kinase 15034.AA Ciliate-A9 274-330 39 2.2e-12 24.95 In-house 89-148 (392) Show / Hide 
Range on Protein: 274-330
Range on HMM: 89-148/392
Sequence Identity: 39% (24 aa)

FHEKDNKSLYIVSEYSEGRTL----KEELADEQPFEEILILHIIQKILSAVAYLHDKRILH
|.| ...  .|| ||  ..||    ||  . .|.| |  |  |...|.|||.|.| | |.|
FCE-SDQNIHIVMEYMKCGTLQQLMKERKKNNQWFNEQEISQIMKCIMSAVMYMHQKNICH
Kinase 15034.AA NEK 249-330 30 4.1e-12 39.35 In-house 47-142 (286) Show / Hide 
Range on Protein: 249-330
Range on HMM: 47-142/286
Sequence Identity: 30% (29 aa)

QNKVL-NEIEILQRIKGPSIQNIIEVFHEKDNKSLYIVSEYSE-GRTLKEE---LADEQ----PFEEILILHIIQKILSAVAYLHDK-----RILH
. . . ||. ||...| | |   .. | |..| .|.|| || | | .| .    .   .    .|||  |... . ...|. |.||.     .|||
KQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILH
Kinase 15034.AA NEK8 253-330 28 2.7e-10 25.47 In-house 48-142 (278) Show / Hide 
Range on Protein: 253-330
Range on HMM: 48-142/278
Sequence Identity: 28% (28 aa)

LNEIEILQRIKGPSIQNIIEVF-HEKDNKSLYIVSEYSEGRTLKEELADEQP---FEEI----------------LILHIIQKILSAVAYLHDKRILH
.|||..| ..  |   |||. . |  ....| |. || .| || . ... |    .||                 .||.  . ..|||...|.. |||
QNEIQVLSMLQHP---NIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILH
Kinase 15034.AA ULK 237-330 18 4.7e-10 31.38 In-house 35-153 (329) Show / Hide 
Range on Protein: 237-330
Range on HMM: 35-153/329
Sequence Identity: 18% (22 aa)

QVRQAKMKDTSRQNK-------VLNEIEILQRIK----GPS----IQNIIEVFHEKDNKSLYIVSEYSEGRTLKEELADEQP----------FEEILILH
.. . ||.  . ..        . |||.|....|    ..     |   ...| ..... .||. || .| .|.. .   ..          ..|  ...
MIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQ

IIQKILSAVAYLHDKRILH
... ||..  .||...| |
FFKQILNGFKELHKHNIIH