14663

Species: Tetrahymena
Alias: 157.m00101, PreTt14663, 14663, 3833.m00865, 1127, TTHERM_00886980
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other

Sequence

Name Sequence Type Origin Length Description Download
14663.AA Protein None 341 None Fasta, JSON
14663.kin_dom Protein Kinase Domain None 66 None Fasta, JSON
14663.NA RNA None 1026 None Fasta, JSON

Protein domain

Protein domains of 14663.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 14663.AA MSK 80-194 27 6.2e-11 33.19 In-house 86-200 (277) Show / Hide
Range on Protein: 80-194
Range on HMM: 86-200/277
Sequence Identity: 27% (32 aa)

GDLQTYLDKNPNLSEEEVRLLFVKIIYPVFILHRCKIYHGDLKPENYLYKICKRTKELFIYLTDFGGADILSSRNEKIHTPYCYSHKFHPINLLDQ---N
| | | . |  . .|.|.|  . ...  |  .|  .| |.|||||| |.    .. .  . |.||| | .. . .|.   ..|..  . .  .|..   .
GELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFD--DEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQ

HPHFNPFSADCYMLGVIL
 . ... . | . |||||
DGGYDE-ACDWWSLGVIL

Kinase 14663.AA Ciliate-E2c 79-125 35 1.4e-09 29.89 In-house 98-145 (310) Show / Hide
Range on Protein: 79-125
Range on HMM: 98-145/310
Sequence Identity: 35% (17 aa)

DGDLQTYLDKNPNLSEEEVRLLFVKIIYPVFILHRC-KIYHGDLKPEN
.|.|. |. ..|...|...  .|  ||. .  ||   .|.|.|.||||
GGTLEQYIYHKPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPEN

Kinase 14663.AA Ciliate-E3 80-159 31 1.8e-09 25.97 In-house 89-165 (202) Show / Hide
Range on Protein: 80-159
Range on HMM: 89-165/202
Sequence Identity: 31% (26 aa)

GDLQTYLDKNPNLSEEEVRLLFVKIIYPVFILHRCKIYHGDLKPENYLYKICKRTKELFIYLTDFGGADILSSRNEK--IHT
|||..|.    |......  .. .||  . ..|  .| |.|.||.| |  . |.   | |   ||| .  |  |..|  .||
GDLYHYIK-QQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNIL--VDKNNNQLIIKICDFGESKQL--RKNKGHTHT

Kinase 14663.AA Ciliate-C8 73-194 23 7.4e-09 28.21 In-house 91-238 (238) Show / Hide
Range on Protein: 73-194
Range on HMM: 91-238/238
Sequence Identity: 23% (35 aa)

FKMKKYD--GDLQTYLDK----NPNLSEEEVRLLFVKIIYPVFILHRCKIYHGDLKPENYLYKICKRTKELFIYLTD------FGGADILSSRNE-----
. |.| .  ..|..|.|.    .  .|...   . . .|  |  ||.  | | | ||.|.|. .   .. . | | |      || |. |.   .     
MEMEKCQQNCNLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLV-CFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSK

KIHTPYCYSHK--------FHPINLLDQNHPHFNPFS--ADCYMLGVIL
|. . . |           | |  . .|.      ||   | | .|..|
KFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL

Kinase 14663.AA NuaK 80-127 39 1.9e-08 17.75 In-house 84-131 (252) Show / Hide
Range on Protein: 80-127
Range on HMM: 84-131/252
Sequence Identity: 39% (19 aa)

GDLQTYLDKNPNLSEEEVRLLFVKIIYPVFILHRCKIYHGDLKPENYL
|.|  |...   |.|.|.| .|  |.  |   |. .| | ||| || |
GELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENIL

Kinase 14663.AA Ciliate-E1 7-188 12 3e-08 23.45 In-house 1-202 (202) Show / Hide
Range on Protein: 7-188
Range on HMM: 1-202/202
Sequence Identity: 12% (26 aa)

LKKGGQAFIIHKGKKSIS----KVFISEKSFQRE----NNIQLNFIQPLNKIFKNKPFAEAYPQKNTKNLNKKEFKMKKYDGDLQTYLD-----------
...|...... . ... .    .. | .  |...    .... . ..... . |...  . . ..  .... . ... ...  |. ||.           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

--KNPNLSEEEVRLLFVKIIYPVFILHRCKIYHGDLKPEN---YLYKICKRTKELFIYLTDFGGADILSSRNEKIHTPYCYSHKFHPINLLD-----QNH
  .. .......  ... .|  . .|| ..|.|.|.||.|   . ..... .        ||| ...| . ...     .| |.. | . .       |.
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC--------DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNK

PHFNPFSADCY
.    .  | |
NQKINYKSDIY

Kinase 14663.AA CAMK-Unique 79-145 21 4.1e-08 22.66 In-house 119-218 (363) Show / Hide
Range on Protein: 79-145
Range on HMM: 119-218/363
Sequence Identity: 21% (22 aa)

DGDLQTYLDK--------------------NPNLSE--EEVRLLFVKIIYPVFILHRCKIYHGDLKPENYLYKICKRTK-------------ELFIYLTD
.|||. ...|                    .  .||   ...... ..   |  .|  .| |.|||.|| .  .|.. |              ..| |.|
GGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIM--VCYSFKDNNHHRDFPYDWSNWHIKLCD

FG
||
FG

S_TKc 14663.AA S_TKc 1-231 17 6.3e-08 -60.63 SMART 1-231 (231) Show / Hide
Range on Protein: 1-231
Range on HMM: 1-231/231
Sequence Identity: 17% (46 aa)

MTKDSLLKKGGQA---FIIHKG--KKSISKVFISEKSFQRENNIQLNFIQPLNKIFKNKPFAEAYPQKNTKNLNKKEFKMKKYDG---DLQTYLDKNPN-
 ..  .. ||. .     .||.  ..   |.    ....|| .|  .       | | . . .          ..  . |   ||   || .|..|..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK---HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LSEEEVRLLFVKIIYPVFILHRCKIYHGDLKPENYLYKICKRTKELFIYLTDFGGADILSSRNEKIHTPYCYSHKFHPINLLDQNHPHFNPFSAD
     ..| ..| ..  |.  .  .|. .| | |||||| |           | ..||| | .|        | .| .  . .  .|     .......|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL--------TTFCGTPWYMAPEVL-----GYGKCKCD

CYMLGVIL-------------SRMSSHLKDISSDLRILLDLLINYE----LQIEQLIL-------FRWI
 . .|.||              .|  ...  |.... ... . ...    . . ..           |.
WWSCGCILYEMLCGYPPFPQMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 14663.AA C8 87-194 23 7.7e-08 23.42 In-house 115-226 (226) Show / Hide
Range on Protein: 87-194
Range on HMM: 115-226/226
Sequence Identity: 23% (27 aa)

DKNPNLSEEEVRLLFVKIIYPVFILHRCKIYHGDLKPENYLYKICKRTKEL-FIYLTDFGGADILSSRNEKIHTPY---CYSHKFHPINLLDQ--NHPHF
.|.  .|.|.   . ...|  |  .|  .| | |.||.|.|  .|   ...  | | ||| |. .|.  ..|..     |   ..     . .  |.  .
NKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFL--VCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQ

NPFSADCYMLGVIL
.    | . .|..|
YRIQSDLFSVGLVL

Kinase 14663.AA Ciliate-E2 80-145 23 1.1e-07 22.41 In-house 119-201 (365) Show / Hide
Range on Protein: 80-145
Range on HMM: 119-201/365
Sequence Identity: 23% (22 aa)

GDLQTYLDKN-----------PNLSEEEVRLLFVKIIY---------------PVFILHRCK-IYHGDLKPENYLYKICKRTKELFIYLTDFG
|||. |. .|            ...|.|.. .. .|..                .  ||  . | | |.|||| |.          | ..|||
GDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------IKIIDFG

Kinase 14663.AA CAMK 80-145 24 1.1e-07 20.12 In-house 145-241 (425) Show / Hide
Range on Protein: 80-145
Range on HMM: 145-241/425
Sequence Identity: 24% (24 aa)

G----DLQTYLDKNPN---------------LSEEEVRLLFVKIIYPVFILHRCKIYHGDLKPENYLYKICKRTKE------------LFIYLTDFG
|    ||  |. ....               ..|.|.| .|  |.  |  .| ..| | |||||| |.   .. ..              | ..|||
GELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFG

Kinase 14663.AA MSK 229-244 50 0.16388 0.87 In-house 242-257 (277) Show / Hide
Range on Protein: 229-244
Range on HMM: 242-257/277
Sequence Identity: 50% (8 aa)

RWINCSEKARDLILKL
.| | |..|.||| .|
AWQNMSPDAKDLIQWL