Gene 3979 (Tetrahymena)

3979

Species: Tetrahymena
Alias: 142.m00076, 647, 3979, TTHERM_00825150, 3683.m00009, PreTt03979
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: NEK

Sequence

Name Sequence Type Origin Length Description Download
3979.NA RNA None 1803 None Fasta, JSON
3979.AA Protein None 600 None Fasta, JSON
3979.kin_dom Protein Kinase Domain None 214 None Fasta, JSON

Protein domain

Protein domains of 3979.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3979.AA NEK 95-222 48 9.6e-76 257.95 In-house 147-286 (286) Show / Hide 
Range on Protein: 95-222
Range on HMM: 147-286/286
Sequence Identity: 48% (69 aa)

SANVFLTKEGI----VKLGDMNVSKVAKQG--LLYT-QTGTPYYASPEVWKDQAYDSKSDIWSLGCVLYEMTTL--KPPFRAE--DMEGLYKKVIRG-YY
..|.||||...    ||.|| ..||| ...  ..|| |.|||||.||||.... |..|||||||||||||| ||  |.||.|.  .|..||.|...| .|
PQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQY

PRIPPH--FSQDLANIIRSLLQVSPQLRPSCAVIKRMNDSLL
|.||.|  .|||| |.|...||..|..||||  |  ......
PPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQI--LEMPFI
S_TKc 3979.AA S_TKc 4-222 24 4.1e-52 180.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-222
Range on HMM: 1-231/231
Sequence Identity: 24% (65 aa)

NQFIQRIGEGAYSSVYKVKRISDDNEYALKKVKLMNLSDKEKQNALNEVRILASIRQPNIIGYKEAFVDEMSNSLCIVMEYADN--GDLYQKISA-----
 .... ||.||...|||.. .... ..|.|..|         .....|..|| . . |||. ....|.|   ..|..||||.|.  |||.. |       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

------------------------------------NVFLTKEGIVKLGDMNVSKVAKQGLLYTQTGTPYYASPEVWKDQAYDS-KSDIWSLGCVLYEMT
                                    |..|..   .|..|  ....      .|. |||.| .|||     |.  |.|.||.||.|||| 
LRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TLKPPFRAEDMEGLYKKVIRGYYPRIPPHFSQDLANIIRSLLQVSPQLRPSCAVIKR-----MNDSLL
. .|||.  .|. ..||.            |... ..|| .||. |. ||..  . .     ...  .
CGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 3979.AA NEK 4-94 48 9.1e-50 171.65 In-house 1-101 (286) Show / Hide 
Range on Protein: 4-94
Range on HMM: 1-101/286
Sequence Identity: 48% (49 aa)

NQFIQRIGEGAYSSVYKVKRISDDNE-----YALKKVKLMNLSDKEKQNAL-NEVRILASIRQPNIIGYKEAFVDEMSNSLCIVMEYAD-NGDLYQK---
 . |. ||.|....||||.|.|| ..     |..||....|.|.||||||. ||||||.... |||..|...|..| .|.|||||||.. .||||||   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

I
|
I
Kinase 3979.AA NEK1 95-210 42 9.8e-46 156.62 In-house 132-266 (276) Show / Hide 
Range on Protein: 95-210
Range on HMM: 132-266/276
Sequence Identity: 42% (57 aa)

SANVFLT--KEG---------------IVKLGDMNVSKVAKQGLLYTQT--GTPYYASPEVWKDQAYDSKSDIWSLGCVLYEMTTLKPPFRAEDMEGLYK
| |.|||  | |               .|||||  ....    ..| .|  ||||| ||| .  . |. ||||||||||||| .||| || |  .  |  
SQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVL

KVIRGYYPRIPPHFSQDLANIIRSLLQVSPQLRPS
|...| || ||||.|..| . . ......|..|||
KICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPS
Kinase 3979.AA NEK4 97-220 46 6e-41 142.35 In-house 132-257 (257) Show / Hide 
Range on Protein: 97-220
Range on HMM: 132-257/257
Sequence Identity: 46% (59 aa)

NVFLTKEGIVKLGDMNVSKVAK--QGLLYTQTGTPYYASPEVWKDQAYDSKSDIWSLGCVLYEMTTLKPPFRAEDMEGLYKKVIRGYYPRIPPHFSQDLA
|.||||  |.|.||. .|.|      .  |  ||||| |||..  ..|| ||||||||| .||| |||  | | ||  |  ..| |  | .|| .||||.
NIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQ

NIIRSLLQVSPQLRPSCAVIKRMNDS
|... .|.  |. |||   | .|   
NLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 3979.AA NEK2 105-222 39 4.6e-38 125.69 In-house 202-319 (319) Show / Hide 
Range on Protein: 105-222
Range on HMM: 202-319/319
Sequence Identity: 39% (47 aa)

IVKLGDMNVSKVAKQGLLYTQT--GTPYYASPEVWKDQAYDSKSDIWSLGCVLYEMTTLKPPFRAEDMEGLYKKVIRGYYPRIPPHFSQDLANIIRSLLQ
.|||||    .. .   .. .|  ||||| |||. ..| |. ||||||.||..||| .|.|||.|     |  |.  | . |||   |..|  || . . 
VVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMIN

VSPQLRPSCAVIKRMNDSLL
| .. |||  .|  . ....
VDHYHRPSIEEI--LQHPQI
Kinase 3979.AA NEK8 96-222 37 2.5e-37 104.03 In-house 148-278 (278) Show / Hide 
Range on Protein: 96-222
Range on HMM: 148-278/278
Sequence Identity: 37% (50 aa)

ANVFLTKE-GIVKLGDMNVSKVAKQG-LLYT---QTGTPYYASPEVWKDQAYDSKSDIWSLGCVLYEMTTLKPPFRAEDMEGLYKKVIRG-YYPRIPPHF
.|.|.|.  ..||.||   ||.     . .|     ||||| |||  . . |. |||.|.|||||||| .||  | |.    |  | ...  |  |. | 
QNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHY

SQDLANIIRSLLQVSPQLRPSCAVIKRMNDSLL
| ..   ....||. |. ||| . |  | . |.
SNEMRMLVHNCLQQDPEQRPSASQI--MAMPLC
Kinase 3979.AA CAMK 97-212 19 1.7e-30 94.95 In-house 209-417 (425) Show / Hide 
Range on Protein: 97-212
Range on HMM: 209-417/425
Sequence Identity: 19% (41 aa)

NVFLTKE-----------------GIVKLGDMNVSKVAKQG-------------------------LLYTQTGTPYYAS-PEVWKD--------------
|. |..                  . .|. |   ... ..|                         ...|. |||.|.. ||| .               
NILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEK

QAYDSKSDIWSLGCVLYEMTTLKPPFRAE-------------DMEGLYKKVIRGYYPRIPPHFS-----------------------QDLANIIRSLLQV
. |. |.|.||.|..|| | . .|||...             ... |..|...| |  .||.||                       |.  . ||..|||
PYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQV

SPQLRPSCA
 |. |....
DPEKRMTIE
Kinase 3979.AA NEK1 5-94 43 9.9e-30 100.39 In-house 2-91 (276) Show / Hide 
Range on Protein: 5-94
Range on HMM: 2-91/276
Sequence Identity: 43% (39 aa)

QFIQRIGEGAYSSVYKVKRISDDNEYALKKVKLMNLSDKEKQNALNEVRILASIRQPNIIGYKEAFVDEMSNSLCIVMEYADNGDLYQKI
  |. ||||..  ...||. .|  .|..|  ..|. ..||.....||| |||  . |||..|||.|. . .  | |||||.|.|||.|||
HYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKI
Kinase 3979.AA NEK6 96-211 42 3.7e-28 89.57 In-house 132-252 (252) Show / Hide 
Range on Protein: 96-211
Range on HMM: 132-252/252
Sequence Identity: 42% (51 aa)

ANVFLTKEGIVKLGDMNVSKV--AKQGLLYTQTGTPYYASPEVWKDQAYDSKSDIWSLGCVLYEMTTLKPPFRAEDME--GLYKKVIRGYYPRIPP-HFS
||||.| .|||||||. . .   .|        ||||| |||  ... |  |||||||||.||||  |. ||  . |    | ||. .  || .|  |.|
ANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPADHYS

QDLANIIRSLLQVSPQLRPSC
..| . .   .. .|..||  
EQLRQLVCMCIHPDPEWRPDI
Kinase 3979.AA Pkinase 96-217 23 3.6e-27 97.13 Pfam 137-290 (293) Show / Hide 
Range on Protein: 96-217
Range on HMM: 137-290/293
Sequence Identity: 23% (36 aa)

ANVFLTKEGIV----KLGDMNVSK---VAKQGLLYTQTGTPYYASPEVWK-DQAYDSKSDIWSLGCVLYEMTTLKPPFRAE------DMEGLYKKVIRGY
.|... ..| .    |..|  ..|     ... ..| .|||.|..||| . .| |..|.|.||.||.|||| . .|||. .      |.  ..... .. 
ENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPP

YPRIPPHFS--------------------QDLANIIRSLLQVSPQLRPSCAVIKRM
...  |  .                    ...  .|...|.. |. ||... |.  
LHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH
Kinase 3979.AA STE 95-210 25 2e-25 86.79 In-house 180-347 (359) Show / Hide 
Range on Protein: 95-210
Range on HMM: 180-347/359
Sequence Identity: 25% (44 aa)

SANVFLTKEGIVKLGDMNVSK-VAK-----------------QGLLYTQTGTPYYASPEVWK------DQAYDSKSDIWSLGCVLYEMTTLKPPFRA-ED
.||..|     ||| |  |.. ...                 |.  .| .||| . .||| .      |. || |.|||||||.. || | |||.    .
PANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHP

MEGLYKKVIR--------------GYYPRIPP-------------------HFSQDLANIIRSLLQVSPQLRPS
|. .. . .               |  |..|.                   ..|... . |.  ||  |. ||.
MRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase 3979.AA Pkinase 4-95 26 8.3e-25 88.8 Pfam 1-96 (293) Show / Hide 
Range on Protein: 4-95
Range on HMM: 1-96/293
Sequence Identity: 26% (26 aa)

NQFIQRIGEGAYSSVYKVKRISDDNEYALKKVKLMNLSDKEKQNALN--EVRILASIRQPNIIGYKEAFVDEMSNSLCIVMEYADNG----DLYQKIS
 .....||.|....||| .....  ..|.|..|. . .....|....  |..|..... |||. ....| |  ......||||...|    ||.  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIS
Kinase 3979.AA ULK 121-203 28 2.3e-23 79.81 In-house 197-307 (324) Show / Hide 
Range on Protein: 121-203
Range on HMM: 197-307/324
Sequence Identity: 28% (32 aa)

LLYTQT------GTPYYASPEVWKDQ-----AYDSKSDIWSLGCVLYEMTTLKPPFRAEDMEGLY-------------KKVIRGYYPRIP-----PHFSQ
...|.       |||.| .|.....|      ||.|.|||||||..||| . |.||..   . .|             .  |.    ..|     |..|.
MCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISP

DLANIIRSLLQV
.. ..|| .||.
ECKDLIRRMLQY
Kinase 3979.AA NEK4 5-93 35 7e-23 79.12 In-house 2-90 (257) Show / Hide 
Range on Protein: 5-93
Range on HMM: 2-90/257
Sequence Identity: 35% (32 aa)

QFIQRIGEGAYSSVYKVKRISDDNEYALKKVKLMNLSDKEKQNALNEVRILASIRQPNIIGYKEAFVDEMSNSLCIVMEYADNGDLYQK
.... .| | |  |. |.   |   | .||..| | | .|.. |. |...|   . |||. ||| .  |    |.||| . . ||||.|
CHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRK
Kinase 3979.AA Ciliate-E2 97-210 20 6.5e-22 72.0 In-house 191-354 (365) Show / Hide 
Range on Protein: 97-210
Range on HMM: 191-354/365
Sequence Identity: 20% (37 aa)

NVFLTKEGIVKLGDMNVSK---------------------------------VAKQGLLYTQTGTPYYASPEVWKDQA---------YDSKSDIWSLGCV
|...     .|. |.  ||                                 . .| . .|. |||.| .||. . .          || |.||||||..
NILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

LYEMTTLKPPFRAEDMEGLYKKVIRGYYP-R----------------IPPHFSQDLANIIRS----LLQVSPQLRPS
|||| . ||||        ... . . .  .                .. . ||.  ..|.     .||. |. |..
LYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT
Kinase 3979.AA CAMK 9-96 15 7.6e-21 63.25 In-house 1-157 (425) Show / Hide 
Range on Protein: 9-96
Range on HMM: 1-157/425
Sequence Identity: 15% (25 aa)

RIGEGAYSSVYKVKRISDD------------NEYALKKVKLMNLS--------------------------DKEKQNALNEVRILAS-------IRQPNI
 .|.|... |........              ..| | ..   |.                          .| ..| ..|..|. .       .. |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IGYKEAFVD-----------EMSN-------SLCIVM---EYADNG----DLYQKISA
|   |.. |             |.        ...||   ||...|    ||...| .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVE
Kinase 3979.AA NEK8 32-95 43 4.2e-20 53.97 In-house 31-92 (278) Show / Hide 
Range on Protein: 32-95
Range on HMM: 31-92/278
Sequence Identity: 43% (28 aa)

LKKVKLMNLSDKEKQNALNEVRILASIRQPNIIGYKEAFVDEMSNSLCIVMEYADNGDLYQKIS
.| . .  .| || | |.||...|. .  ||||.| . | ..  |.| |.||||| | |||.|.
WKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMED--NTLMIEMEYADGGTLYQMIQ
Kinase 3979.AA STE 4-94 24 3.1e-18 61.07 In-house 1-128 (359) Show / Hide 
Range on Protein: 4-94
Range on HMM: 1-128/359
Sequence Identity: 24% (31 aa)

NQFIQRIGEGAYSSVYKVKRI------SDDNE---------YALKKVKLMNLS---------------DKEKQNALNEVRILASIR--QPNIIGYKEAFV
 ..|..||.||. .||| ...      . ...         .| |...| | .               ..|.|. |.|..|.   .   |||. |  ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DE-----MSNSLCIVMEYADNGDLYQKI
.|       ..|.|.||| |.| | . |
KEGHNHKNDDELWICMEYMDGGSLDDII
Kinase 3979.AA Ciliate-E2 4-94 25 4.5e-18 58.62 In-house 1-125 (365) Show / Hide 
Range on Protein: 4-94
Range on HMM: 1-125/365
Sequence Identity: 25% (32 aa)

NQFIQRIGEGAYSSVYKVKRISDDNEYALK-------------KVK-----LMNLSDKEKQNALNEVRIL----------------ASIRQPNIIGYKEA
  ||. ||.|...||||.|........|.|             |||     . ... ..... ..| .|.                 ..  |||| ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FVDEMSNSLCIVMEYADNGDLYQKI
| ..  |.. .||||.. |||.. |
FQEKDDNNIYLVMEYCQGGDLFDYI
Kinase 3979.AA NEK6 5-94 37 1.6e-17 53.97 In-house 2-90 (252) Show / Hide 
Range on Protein: 5-94
Range on HMM: 2-90/252
Sequence Identity: 37% (34 aa)

QFIQRIGEGAYSSVYKVKRISDDNEYALKKVKLMNLSD-KEKQNALNEVRILASIRQPNIIGYKEAFVDEMSNSLCIVMEYADNGDLYQKI
|  ..|| | .| ||. . . || . |||||.. .. | | .|  . |. .| ..  ||.| | ..|...  | | ||.| || ||. . |
QIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIEN--NELNIVLELADAGDMSRMI
Kinase 3979.AA ULK 4-90 22 4.4e-15 50.01 In-house 1-104 (324) Show / Hide 
Range on Protein: 4-90
Range on HMM: 1-104/324
Sequence Identity: 22% (23 aa)

NQFIQRIGEGAYS-SVYKVK-RISD--DNEYALKKVKLMNLSDKEKQ--------NALNEVRILASIR---QPN--IIGYKEAFVDEMSNSLCIVMEYAD
 . ....|.|..   ||| .  ...  .  .| |.. . ....|...        .  ||..|.  .     ||  |. ... | .  .| ..|.||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDL
 |||
GGDL
Kinase 3979.AA NEK2 5-95 34 8.1e-15 46.22 In-house 2-92 (319) Show / Hide 
Range on Protein: 5-95
Range on HMM: 2-92/319
Sequence Identity: 34% (31 aa)

QFIQRIGEGAYSSVYKVKRISDDNEYALKKVKLMNLSDKEKQNALNEVRILASIRQPNIIGYKEAFVDEMSNSLCIVMEYADNGDLYQKIS
.  . ||.| . ...||.|.||    . |  .  ..  ||.|   .|. ||   . |||. |    .|. . .| |||||   ||| | |.
EVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIK
Kinase 3979.AA TyrKc 4-221 18 6.1e-13 -13.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-221
Range on HMM: 1-280/280
Sequence Identity: 18% (53 aa)

NQFIQRIGEGAYSSVYKVKRISDDNEYALKKVKLMNLSDKEKQNALNEVRILASI--RQPNIIGYKEAFVDE-----MSNSLCIVMEYADNGDLYQKI--
 .... .||||.  ||| . .    . | |..|        ..  ..| ||. ..  . |||.    . ...      .  |.|||||...||| . .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

SA-----------------------------------NVFLTKEGIVKLGDMNVSKVAKQG-------LLYTQT---GTP-----YYASPEVWKDQAYDS
.                                    |. ......|| .|   |.  . .         |...   |.         .||....  . .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDIWSLGCVLYEMTTL-KPPFRA-----EDMEGLYKKVIRGYYPRIPPH--------FSQDLANIIRSLLQVSPQLRPSCAVIKRMNDSL
|||.|| | ...|. |. ..|         . . ....| .||....||.         .... .|...  .  |  ||. . |    . .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase 3979.AA Pkinase_Tyr 133-210 23 8.1e-08 27.11 Pfam 182-262 (270) Show / Hide 
Range on Protein: 133-210
Range on HMM: 182-262/270
Sequence Identity: 23% (19 aa)

SPEVWKDQAYDSKSDIWSLGCVLYEMTTL-KPP-FRAEDMEGLYKKV-IRGYYPRIPPHFSQDLANIIRSLLQVSPQLRPS
.||....  . .|||.|| | ...|. |. . | .   . | .|...  .||   .|.. .... .....  .  |. ||.
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPT
Kinase 3979.AA Pkinase_Tyr 5-91 25 8.6e-05 16.86 Pfam 2-95 (270) Show / Hide 
Range on Protein: 5-91
Range on HMM: 2-95/270
Sequence Identity: 25% (24 aa)

QFIQRIGEGAYSSVYKVKRI----SDDNEYALKKVKLMNLSDKE--KQNALNEVRILASI-RQPNIIGYKEAFVDEMSN-SLCIVMEYADNGDLY
.|.. .||||. .||| .      ... . | |..   . ....  ..  ..|..|. .. . |||. .  . .|.    ...|||||. .|||.
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL