Gene 24902 (Tetrahymena)
24902
Sequence
Protein domains of 24902.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 24902.AA | NEK | 4-258 | 49 | 2.5e-162 | 545.58 | In-house | 1-286 (286) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-286/286 Sequence Identity: 49% (141 aa) YETVKLIGSGAFGQVYLVKHKREDKM-----YVNKKIKTRDMSQKDRENTE-NEVRLLQKLRHANIVAYKDSYMDRE-QYLNIVMIHCE-GGDMHNR--- || .| ||.|.||.||.|..|. |. || |||.. ||.|...|. ||||.|..|.| |||.|.||..... ..|.||| .|| |||.... YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS IKNQK--GKNFPEDQIQDWLAQMALALFYLHEK-----KILHRDLKTQNIFLKS-GR----VRLGDFGIAKVLDSTRDFANT-CIGTPYYMSPELFKYKP ||.|| ||.|.|.|| ||..||.||| |.|.. ||||||.|.||||| . .. |..|||||.|||..|.|.|.| ..|||||||||... || IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP YSYKSDIWAFGCVLYEMCNL--RHAFDAQ--SLNGLAVKIMNG-TYPPINST--YSKSLRDLIGKMLQLNPKSRPSILDIINTSFV |..|||||..|||||||| | .|.|.|. ....|..|||.| .||||.|. ||. |..|| .||| .|..|||. .|....|. YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | 24902.AA | NEK1 | 4-258 | 47 | 2.8e-125 | 422.48 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-276/276 Sequence Identity: 47% (131 aa) YETVKLIGSGAFGQVYLVKHKREDKMYVNKKIKTRDMSQKDRENTENEVRLLQKLRHANIVAYKDSYMDREQ-YLNIVMIHCEGGDMHNRIKNQ--KGKN |. | ||.|.|| ..||||| . ..|| | |. |..|.||. ||| .|.|..| |||.||.| . . | ||| |.|||. .|..| ||| YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL FPEDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFLK---SG---------------RVRLGDFGIAKVLDSTRDFANTCIGTPYYMSPELFKYKPYSY |.|||| .| |. ||| . | .||||||.|.||||| .| |.|||||||..| .| ..|.|||||||| |||. ||| FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN KSDIWAFGCVLYEMCNLRHAFDAQSLNGLAVKIMNGTYPPINSTYSKSLRDLIGKMLQLNPKSRPSILDIINTSFV |||||. |||||| | | |.|.|... | || |||||| ..||. |. |. .|.. ||..|||. .| |. KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI |
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| Kinase | 24902.AA | NEK4 | 4-258 | 48 | 1.1e-120 | 407.19 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-257/257 Sequence Identity: 48% (125 aa) YETVKLIGSGAFGQVYLVKHKREDKMYVNKKIKTRDMSQKDRENTENEVRLLQKLRHANIVAYKDSYMDREQ-YLNIVMIHCEGGDMHNRIKNQKGKNFP |. .| .| | .| |.||.|.| | || ||.. . |...| .| |..|| .|.| ||| ||.|. . .| ||| |||||. .. | ||.. . YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE EDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFL-KSGRVRLGDFGIAKVLDSTRDFANTCIGTPYYMSPELFKYKPYSYKSDIWAFGCVLYEMCNLRH | |. .| | |.|| |.|||.||||||||||||| | ...|||||..||. |.| | ||||||||||.| .|| ||||||. || .||| |.| EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKH AFDAQSLNGLAVKIMNGTYPPINSTYSKSLRDLIGKMLQLNPKSRPSILDIINTSFV |||| .| | .|..| ||. ||. | .|. .||. |. |||| ||. .. AFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI |
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| Kinase | 24902.AA | NEK8 | 4-258 | 37 | 1.9e-100 | 287.48 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-278/278 Sequence Identity: 37% (106 aa) YETVKLIGSGAFGQVYLVKHKRED--KMYVNKKIKTRDMSQKDRENTENEVRLLQKLRHANIVAYKDSYMDREQYLNIVMIHCEGGDMHNRIKNQKG-KN || . .| |||| . | | . . . | | . .|| | | ||...| .| |.||..| |. |. .. | |.| ..|| | |.. . YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFME-DNTLMIEMEYADGGTLYQMIQHQQNKLF FPED----------------QIQDWLAQMALALFYLHEKKILHRDLKTQNIFL-KS-GRVRLGDFGIAKVLDSTRDFAN--TCIGTPYYMSPELFKYKPY ..| .| . . || .|. ..|.. ||||||||||||. .. . | .|||||.|.. . . | .|||||||||. . ||| EEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPY SYKSDIWAFGCVLYEMCNLRHAFDAQSLNGLAVKIMNG-TYPPINSTYSKSLRDLIGKMLQLNPKSRPSILDIINTSFV |||.|| |||||||| |. ||.| | | .||| . .| || . ||. .| |. ||. | ||| | . NQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC |
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| Kinase | 24902.AA | S_TKc | 4-258 | 31 | 1.5e-92 | 314.66 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-231/231 Sequence Identity: 31% (86 aa) YETVKLIGSGAFGQVYLVKHKREDKMYVNKKIKTRDMSQKDRENTENEVRLLQKLRHANIVAYKDSYMDREQYLNIVMIHCEG--GDMHNRIKNQKGKN- || ...||.||||.||...||. .. . |.|| |....|...|.| .| ||| ..|.. | ..| .|| .|.| ||.. .||..... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FPEDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFLKSGRVRLGDFGIAKVLDSTRDFANTCIGTPYYMSPELFKYKPYSY-KSDIWAFGCVLYEM ||| ... ...|...|| |.|...|.||||| .||.| . .. ..|||.|..| .|..|||.||.||.. .|.. |.|.|..||.|||| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM CNLRHAFDAQSLNGLAVKIMNGTYPPINSTYSKSLRDLIGKMLQLNPKSRPSILDIIN-------TSFV . . |. .. . ||. |....|.| |.|| .|. ||.. .. . .. LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 24902.AA | Pkinase | 4-258 | 27 | 5.8e-85 | 293.36 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-293/293 Sequence Identity: 27% (83 aa) YETVKLIGSGAFGQVYLVKHKREDKMYVNKKIKTRDMSQKDRENTEN--EVRLLQKLRHANIVAYKDSYMDREQYLNIVMIHCEGG----DMHNRIKNQK |.... ||||.||.||. .|| . |... |.|| |. . . ... . |......|.| ||| ..|...| .... .|| .|||| | . .|. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR GKNF--PEDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFLK-SGRV----RLGDFGIAKVL-DSTRDFANTCIGTPYYMSPELFK-YKPYSYKSDIWA ...| .|....... |.. .| |.|...|.||||| .||... | . ...|||.||.. ..| |||.||.||. . ...|..|.|.|. HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS FGCVLYEMCNLRHAFDAQ----SLNGLAVKIMNGTYPPINSTYS-----------------------KSLRDLIGKMLQLNPKSRPSILDIINTSFV .||.||||.. | |. . . . ..| . .||. . .. ....|.| ..|...||.||.. .| . .. CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 24902.AA | NEK-Unclassified | 4-258 | 37 | 1.9e-79 | 262.67 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-258/258 Sequence Identity: 37% (98 aa) YETVKLIGSGAFGQVYLVKHKREDKMYVNKKIKTRDMSQKDRENTENEVRLLQKLRHANIVAYKDSYMDREQYLNIVMIHCEGGDMHNRIKNQKGK--NF |. . .| | | ||||.|. . | ..| | | . | . .| .||| || | ||. . . | |.||.. ||. . .| | YDKITTLGQGGGGAVYLVRHQISKRHLV-QQISKR----KKKKKRQNKIIILSQLRHPHIVTYHDSFFENAK-LFYTQDYCDGGNLDRRIQKHRKKNEPF PEDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFL-KSGRVRLGDFGIAKVLDSTRDFANTCIGTPYYMSPELFKYKPYSYKSDIWAFGCVLYEMCNLR | | | || |. | | .||.|||||.||||| .. | .|||||....| ||| | ||.||. .|||| . .|| .||.|. ||..|||| DEGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCE HAFDAQSLNGLAVKIMNGTY------PPINSTYSKSLRDLIGKMLQLNPKSRPSILDIINTSFV .||.... . || . |. .||| | ..| ||. |. ||| ..|. .. PFFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI |
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| Kinase | 24902.AA | NEK2 | 4-258 | 31 | 1.1e-73 | 247.54 | In-house | 1-319 (319) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-319/319 Sequence Identity: 31% (102 aa) YETVKLIGSGAFGQVYLVKHKREDKMYVNKKIKTRDMSQKDRENTENEVRLLQKLRHANIVAYKDSYMDREQ-YLNIVMIHCEGGD---MHNRIKNQKGK || . ||.| ||... |..| | | | |. | | . .|. .|..|.| ||| | | ||.. | ||| .||||| | . .... . YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKER-Q NFPEDQIQDWLAQMALALFYLHE------------------KK---ILHRDLKTQNIFL-KSGR------------------------------------ ..| | ..|. .|| | . |||||.| |||| . YMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYS ---VRLGDFGIAKVLDSTRDFANTCIGTPYYMSPELFKYKPYSYKSDIWAFGCVLYEMCNLRHAFDAQSLNGLAVKIMNGTYPPINSTYSKSLRDLIGKM | ||||| |..| || | .|||||||||. . .|. |||||. ||..|||| |. | | . |..|| .| . .| . ||. | ..| | QVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFM LQLNPKSRPSILDIINTSFV . .....|||| |. ... INVDHYHRPSIEEILQHPQI |
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| Kinase | 24902.AA | CAMK | 9-258 | 19 | 3.7e-73 | 234.86 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 9-258
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)
LIGSGAFGQVYLVKHKRED------------KMYVNKKIKTRDMS--------------------------QKDRENTENEVRLLQK-------LRHANI
.|.|.||.|.|..||. . . | |... .. .|||.| ..|.....| |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VAYKDSYMDREQ------------------YLNIVM---IHCEGG----DMHNRIKNQKG-------------KNFPEDQIQDWLAQMALALFYLHEKKI
. . | |... .. .|| .|.|| |. ..|. ... . |.|.. . . |.. |. |.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
LHRDLKTQNIFLKS------------------GRVRLGDFGIAKVLDS-----------------------TRDFANTCIGTPYYMS-PELFKY------
||||| || | . . . . ||| |...|. . . .|. |||.||. ||....
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
--------KPYSYKSDIWAFGCVLYEMCNLRHAFDAQ-------------SLNGLAVKIMNGTYPPI------------------------NSTYSKSLR
..|..|.|.|. |..|| | . |.. ... | |||.| | . . . |.. .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECK
DLIGKMLQLNPKSRPSILDIINTSFV
||| |||| .|. |..| .. | ..
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 24902.AA | STE | 4-258 | 22 | 5.9e-71 | 242.03 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-359/359 Sequence Identity: 22% (83 aa) YETVKLIGSGAFGQVYLVKHKR---------------EDKMYVNKKIKTRDMSQ---------------KDRENTENEVRLLQKLR--HANIVAYKDSYM .| .. ||.||||.||. ... ... |... .. .. ..... ..|.....|.. | ||| | ..|. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF DR------EQYLNIVMIHCEGGDMHNRIKNQKGKNFP------------EDQIQDWLAQMALA-LFYLHEKKILHRDLKTQNIFLKSGRVRLGDFGIAKV . ...|.|.| ...|| ||. .|...| |.|| . | . | |||...| |||.| .||.| | | |||... KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ LDS---------------TRD-FANTCIGTPYYMSPELFKY------KPYSYKSDIWAFGCVLYEMCNLRHAF-DAQSLNGLAVKIMN------------ |.. |.. ||..||| .|.|| . |.|..|.||| .||.. ||.. .. . | . . . ...| LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCI --GTYPPINS-------------------TYSKSLRDLIGKMLQLNPKSRPSILDIIN--TSFV |. ||. . .|....| | | || .|. ||. . .. .|. VNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | 24902.AA | ULK | 4-258 | 26 | 3.3e-70 | 239.55 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-329/329 Sequence Identity: 26% (88 aa) YETVKLIGSGAFGQVYLVKHKRE----DKMYVNKKIKTRDMSQKDREN--------TENEVRLLQKLR--------HANIVAYKDSYMDRE-QYLNIVMI |. . .|.|.||.|| ..|. ..... |.| |.|| |. .||.....|| | ||| ..| ... .. |.| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME HCEGGDMHNRIKNQKG--------KNFPEDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFLKSG-------------RVRLGDFGIAKVLDST---RD |.||| . ||..|. |...|.... . | . .. .||...| |||.| ||| .. | .. ..||| ||..|. . YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ FANTCI------GTPYYMSPELFKYK----PYS-YKSDIWAFGCVLYEMCNLRHAFDAQSLNGLAVKIMNGT------------YPPIN-------STYS . || |||.||.|.... . ||. ||.||| .||..||| . | |. | . .|.. |.. . | MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS KSLRDLIGKMLQLNPKSRPSILDIINTSFV . ..||| .||| ..| | |. ...| .. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 24902.AA | NEK11 | 4-258 | 40 | 2.9e-68 | 233.1 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-259/259 Sequence Identity: 40% (104 aa) YETVKLIGSGAFGQVYLV---KHKREDKMYVNKKIKTRDMSQKDRENTENEVRLLQKLRHANIVAYKDSYMDREQYLNIVMIHCEGGDMHNRIKNQK--G | . .|||.|| |||| | || . . | | | .. . | || .| | || . |.|. ... |. ||| |. .||. | | YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQDNFC-IITEYCEGRDLDYRIQEYKQAG KNFPEDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFLKSGRVRLGDFGIAKVLDSTRDFANTCIGTPYYMSPELFKYKPYSYKSDIWAFGCVLYEMCN | ||| || .| |. | |.||..||||||| .||||| ...||||....| | | | ||| ||||| | . | |||||. |.||||| KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCC LRHAFDAQSLNGLAVKIMNGTYPPINSTYSKSLRDLIGKMLQLNPKSRPSILDIINTSFV . ||| . . ..|. | | . | . | .. .|| || ||| ||. .. MDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM |
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| Kinase | 24902.AA | Pkinase_Tyr | 4-199 | 24 | 6.5e-29 | 98.54 | Pfam | 1-210 (270) | Show / Hide |
Range on Protein: 4-199 Range on HMM: 1-210/270 Sequence Identity: 24% (52 aa) YETVKLIGSGAFGQVYLVKHK-REDKMYVNKKIKTR--DMSQKD--RENTENEVRLLQKL-RHANIVAYKDSYMDREQY--LNIVMIHCEGGDMHNRIKN . | .|.||||.||. . | .|. . .|. . .... || .|.... .| .| ||| . .|... . ||| ....||... .. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK Q--KGKNFPEDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFLK-SGRVRLGDFGIAKVL--DSTR-DFANTCIGTPYYMSPELFKYKPYSYKSDIWAF . ..... .. .. .| | .. ||..|.. |||| . |. .. .. |. .||| |. . |.. . . |.|| ..|. .. |||.|.| HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF GCVLYEMCNL | ...|.. . GVLMWEIFTY |
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| Kinase | 24902.AA | TyrKc | 4-258 | 20 | 6.8e-21 | 76.65 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 4-258 Range on HMM: 1-280/280 Sequence Identity: 20% (61 aa) YETVKLIGSGAFGQVYLVKHKREDKMYVN---KKIKTRDMSQKDRENTENEVRLLQKL--RHANIVAYKDSYMDRE------QYLNIVMIHCEGGDMHNR . | .|.||||.||. . | .. |..| || .| |.. || .| |||. .. . . | ||| ....|| ... ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY IKNQKGKNFPEDQIQDWLAQMALALFYLHEKKILHRDLKTQNIFLKSGR-VRLGDFGIAKVLDST-------RDFAN----TCI--GTPYYMSPELFKYK ... ..| .. .. .. | | |||.|.. |||| . |. ..... |. .||| .. ... . |.|| ..|. LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG PYSYKSDIWAFGCVLYEMCNLRHAFDAQ------SLNGLAVKIMNGTYPPINST--------YSKSLRDLIGKMLQLNPKSRPSILDIINTSFV .. |||.|.|| ...|.. . | . ....| ..|. .. . ... . . .|..||. .| .. KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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