Gene 2122 (Tetrahymena)
2122
Sequence
Protein domains of 2122.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | 2122.AA | NEK | 40-296 | 44 | 9.40000000001e-154 | 517.09 | In-house | 1-286 (286) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-286/286 Sequence Identity: 44% (128 aa) YRELEQIGKGTSGTVFLVKSKQDKKF-----YIAKKIILTNLNEQERQAVE-QELILLKKLKHPHIVGYKENFLEPY--YMIIIMEYCE-QGDLSFH--- |.....||.| |.|..|..|.|.| |. ||| ..|..|.|.|. .| ..||.||||.||.|.. |.| ...|.||||| |||. . YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS IKQKLKENDHFPENIILNWFIQLTMALDFIHEK-----HVLHRDVKSSNIFLTSSGS----IKLGDFGISKVLHSTADKAQT-LIGTPYYLSPEVCENKP ||.. .....|.|..|..||||. .||...|.. ..|||| |..|||||.... .|.||||||||| .|.|.|.| ..|||||.|||||.||| IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP YTYQSDIWALGCVLFEMCAL--KHPFVSE--SLMALVVKIIRE-PNPNIPNM--YSSDLNCLVQILLAKKPESRPRTKQILSFPFV |.. ||||.|||||.|||.| |||| .. ....|..||... | || . ||.||. |.. .| | ||.|| ..|||..||. YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
|||||||||
Kinase | 2122.AA | NEK1 | 40-296 | 44 | 2.1e-116 | 392.99 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-276/276 Sequence Identity: 44% (123 aa) YRELEQIGKGTSGTVFLVKSKQDKKFYIAKKIILTNLNEQERQAVEQELILLKKLKHPHIVGYKENFLEPYY--MIIIMEYCEQGDLSFHIKQKLKENDH | .. |||.|. | ..|||.| | . | | | ... |.||... | ..|.|.||| ||.||| | | . |.||||. ||| |... . YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL FPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLT--SSG---------------SIKLGDFGISKVLHSTADKAQTLIGTPYYLSPEVCENKPYTY |.| |..||.|. .|| .|| . .|||| ||.||||| ..| .|||||||...| .| . |.| |||||||||| |.||||. FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN QSDIWALGCVLFEMCALKHPFVSESLMALVVKIIREPNPNIPNMYSSDLNCLVQILLAKKPESRPRTKQILSFPFV ||||.||||| | |.||||| . .. .|| ||.. . | ||. || .| || .. . |..|| . |||. ||. KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI |
|||||||||
Kinase | 2122.AA | NEK4 | 40-296 | 46 | 1.4e-102 | 347.05 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-257/257 Sequence Identity: 46% (121 aa) YRELEQIGKGTSGTVFLVKSKQDKKFYIAKKIILTNLNEQERQAVEQELILLKKLKHPHIVGYKENF-LEPY-YMIIIMEYCEQGDLSFHIKQKLKENDH | . ..||| | |.||....||| |. ||. | | .||.| |.| || .|||| || ||| . | .. |.| .|| ||| || . |. YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQ--QKNQF FPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSSGSIKLGDFGISKVLHSTADKAQTLIGTPYYLSPEVCENKPYTYQSDIWALGCVLFEMCAL .|. ...||.| ||| ..||||.|||| | ||||| ||.||||||.|| .| |.|.||||||.|||. |.|| | ||||.||| ..|| | LEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITL KHPFVSESLMALVVKIIREPNPNIPNMYSSDLNCLVQILLAKKPESRPRTKQILSFPFV || | . |. .|| | .| || || || .| |.|. || .|. |.. KHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI |
|||||||||
Kinase | 2122.AA | NEK8 | 46-296 | 39 | 4.7e-89 | 254.38 | In-house | 7-278 (278) | Show / Hide |
Range on Protein: 46-296 Range on HMM: 7-278/278 Sequence Identity: 39% (108 aa) IGKGTSGTVFLVKSKQDK--KFYIAKKIILTNLNEQERQAVEQELILLKKLKHPHIVGYKENFLEPYYMIIIMEYCEQGDLSFHI---KQKLKENDH--- .|.| | . | | | . | | | .. . | |||. | .|..| || |..| ..|.| | |||.. | | | . || |. VGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFEEERQLK ---------FPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSS-GSIKLGDFGISKVLHSTADKAQT---LIGTPYYLSPEVCENKPYTYQSDI |.| || |.| |. ..|.. .|||| | |||.| . . .|.|||||||.. .| ..|| ..|||||.||| || ||| ||. QVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIM-NTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDM WALGCVLFEMCALKHPFVSESLMALVVKIIR--EPNPNIPNMYSSDLNCLVQILLAKKPESRPRTKQILSFPFV |||||||.||| || | . | |||.||.. . .| |. ||... || .|.. || || ||.. | . WALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEP-ISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC |
|||||||||
Kinase | 2122.AA | S_TKc | 40-296 | 29 | 7.6e-84 | 285.77 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-231/231 Sequence Identity: 29% (79 aa) YRELEQIGKGTSGTVFLVKSKQDKKFYIAKKIILTNLNEQERQAVEQELILLKKLKHPHIVGYKENFLEPYYMIIIMEYCEQ--GDLSFHIKQKLKENDH |. |..||||. |.|.... | ... . |.| . ...|. .||| .||.|| ... | . .. ..||||.. ||| .||.. .. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --FPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSSGSIKLGDFGISKVLHSTADKAQTLIGTPYYLSPEVCENKPYTY-QSDIWALGCVLFEM ||| . .. |. ||...|.....|||.| .||.|.. ||..|||....| |..|||.|..|||. .|.. .|.|..||.|.|| FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM CALKHPFVSESLMALVVKIIREPNPNIPNMYSSDLNCLVQILLAKKPESRPRTKQILS-------FPFV .. . || |... |.|. |... ... .| | || || ..| |.. LCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | 2122.AA | NEK-Unclassified | 40-296 | 34 | 2.9e-80 | 265.42 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-258/258 Sequence Identity: 34% (90 aa) YRELEQIGKGTSGTVFLVKSKQDKKFYIAKKIILTNLNEQERQAVEQELILLKKLKHPHIVGYKENFLEPYYMIIIMEYCEQGDLSFHIKQKLKENDHFP | . .|.| | |.||. . |. . . | . || .|.| .|.||||| | . | | . .||. |.| |. . | |. | YDKITTLGQGGGGAVYLVRHQISKRHLVQQ--ISKRKKKKKRQ---NKIIILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFD ENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSSGSIKLGDFGISKVLHSTADKAQTLIGTPYYLSPEVCENKPYTYQSDIWALGCVLFEMCALKH | .| |.||. ||. .|| . ..||| | .||||| . . .||||||... | |||.| .||. ..|||||. .|| .||.|.|||...|||. EGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEP PFVSESLMALVVKIIREPN-------PNIPNMYSSDLNCLVQILLAKKPESRPRTKQILSFPFV | .. . || ...| | . || || .. .| . .. || |.. ... FFDTHNMGEVYMKIKQDDNRLEEALEP-VSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI |
|||||||||
Kinase | 2122.AA | Pkinase | 40-296 | 25 | 5.5e-73 | 253.59 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-293/293 Sequence Identity: 25% (77 aa) YRELEQIGKGTSGTVFLVKSKQDKKFYIAKKIILTNLNEQERQAVEQ--ELILLKKLKHPHIVGYKENFLEPYYMIIIMEYCEQG----DLSFHIKQKLK |. ...||.|..|.|.. . | . | . |.| . . .....|. |. ..|.|.||.|| ... | .. .. ..||||| | ||. .|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W ENDHF--PENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSSGSI----KLGDFGISKVL-HSTADKAQTLIGTPYYLSPEVCE-NKPYTYQSDIW .. | .|. . ... |. .|...|.. ..|||.|..||.. . | | |..|||..|.. . ..|. |||.|..|||. ...|.. .|.| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW ALGCVLFEMCALKHPFVSE------SLMALVVKIIR-EPNPNIPNMYS-------------------SDLNCLVQILLAKKPESRPRTKQILSFPFV ..||.|.||. . || .. . |.....| . .. ..|. .| ... .. .|.|.|..|| .||| |.. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
|||||||||
Kinase | 2122.AA | NEK2 | 40-296 | 31 | 3.9e-69 | 231.94 | In-house | 1-319 (319) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-319/319 Sequence Identity: 31% (99 aa) YRELEQIGKGTSGTVFLVKSKQDKKFYIAKKIILTNLNEQERQAVEQELILLKKLKHPHIVGYKENFL--EPYYMIIIMEYCEQGDLSFHIKQKLKENDH | |. ||.| |.. |. | |.| . | | ...| |.|. | .|..|||| || | . |.||||| |||| || || YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY FPENIILNWFIQLTMALDFIHE------------------KH---VLHRDVKSSNIFLTSSGS------------------------------------- ..| .|. . ||. || .| . .|||| | |||| . .. MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ --IKLGDFGISKVLHSTADKAQTLIGTPYYLSPEVCENKPYTYQSDIWALGCVLFEMCALKHPFVSESLMALVVKIIREPNPNIPNMYSSDLNCLVQILL .|||||| ..| |.| .||||| |||. . .| ||||..||...|||||. || . .| .|| || ||..|| .. . VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI AKKPESRPRTKQILSFPFV . ....|| . || |.. NVDHYHRPSIEEILQHPQI |
|||||||||
Kinase | 2122.AA | NEK11 | 40-296 | 39 | 3.5e-68 | 232.81 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-259/259 Sequence Identity: 39% (103 aa) YRELEQIGKGTSGTVFLV---KSKQDKKFYIAKKIILTNLNEQERQAVEQELILLKKLKHPHIVGYKENFLEPYYMIIIMEYCEQGDLSFHIKQKLKEND | ..| | |||.|| | |. . | | || | | || .|.|| || . |.| || |||| || .|. . YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQDNFCIITEYCEGRDLDYRIQEYKQAGK HFPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSSGSIKLGDFGISKVLHSTADKAQTLIGTPYYLSPEVCENKPYTYQSDIWALGCVLFEMCA |||| |. ||||| . |..||. .||||.|| |||| .|.||||.|..| | | || ||| |.||| . | .||||.| |.|.||| IFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNN-LLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCC LKHPFVSESLMALVVKIIREPNPNIPNMYSSDLNCLVQILLAKKPESRPRTKQILSFPFV . | | . ...|..|. | .|. | .|| .. .| | | || .|| |.. MDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM |
|||||||||
Kinase | 2122.AA | STE | 40-296 | 24 | 1.6e-66 | 227.31 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-359/359 Sequence Identity: 24% (88 aa) YRELEQIGKGTSGTVFLVKSKQ---------------DKKFYIAKKIILTNLN---------------EQERQAVEQELILLKKLK--HPHIVGYKENFL .. .|.||||..|||.. . . .... |.. | | | ..|.| ...|. ..||.. ||.|| | .. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF EPY-------YMIIIMEYCEQGDLSFHIKQKLKEND----------HFPENIILNWFIQLTMA-LDFIHEKHVLHRDVKSSNIFLTSSGSIKLGDFGISK . |.|||.. | |. ||.| . .. .|||..| |. . |...|..|. |||.|..||.| .|| |||... KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG VLHS---------------TAD-KAQTLIGTPYYLSPEVCEN------KPYTYQSDIWALGCVLFEMCALKHPFVSESLM-ALVVKIIR----------- | . | . | .|..||| . .||| .. |.|....||| |||.. ||. |.|. .. | |. ... QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ---EPNPNIPN-------------------MYSSDLNCLVQILLAKKPESRPRTKQILS--FPFV .| | .|. .|.... .. | | |. || ..| |. ||. IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
|||||||||
Kinase | 2122.AA | Ciliate-E2 | 40-296 | 21 | 1.7e-64 | 220.27 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-365/365 Sequence Identity: 21% (82 aa) YRELEQIGKGTSGTVFLVKSKQDKKFY------------------IAKKIILTNLNEQERQAVEQELILLK----------------KLKHPHIVGYKEN | ...||.|. |.|...| ....| . .|.. . ...... ....||. ... .|.||.|. ..| YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FL--EPYYMIIIMEYCEQGDLSFHIKQK-LKENDHFP------ENIILNWFIQLT---------------MALDFIHEKH-VLHRDVKSSNIFLTSSGSI | .. ..||||..||| .||.. .|.| ... |. |.. . |.. || ..|.|. ..||| | .||.. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLGDFGISKVLHS-------------------------------TADKAQTLIGTPYYLSPEVCENKP---------YTYQSDIWALGCVLFEMCALKHP |. |||.|| .. . ..|..|||.|..||. ..|. |.|..|||.||..|.||. |.| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FVSESLMALVVKIIREPNPNIPNM------------------YSSDLNCLVQI----LLAKKPESRPR-TKQILSFPFV | ..| . . ..|. | . | . .| |.|| |. .||| |. F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
|||||||||
Kinase | 2122.AA | ULK | 40-296 | 24 | 7.7e-64 | 218.41 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 40-296 Range on HMM: 1-329/329 Sequence Identity: 24% (81 aa) YRELEQIGKGTSGTVFLVKSKQDK---KFYIAKKIIL---TNLNEQERQ------AVEQELILLKKLK--------HPHIVGYKENFLEP--YYMIIIME | ...|||. |.|. . |..| . ..| |.|. | ...|.. ...| ..|||| ||.|| ... | .. . |||| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YCEQGDLSFHIKQKLK------ENDHFPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSS------------GSIKLGDFGISKVLHST---AD ||..|||. ||.. | |. ...|..... |.|. .. ..|.. . ||| | .|| .. | .|..||| .|.. . .. YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ KAQTLI------GTPYYLSPEVCE----NKPYT-YQSDIWALGCVLFEMCALKHPFVSESLMALVVKIIREP--------------NPNIP-----NMYS ..| |||.| .|.. . .|||. | .||| |||...|| | ||.. . .. .||.. ....| . | MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS SDLNCLVQILLAKKPESRPRTKQILSFPFV ... | . .| .... | .... |.. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
|||||||||
Kinase | 2122.AA | Pkinase_Tyr | 40-237 | 21 | 3.9e-18 | 62.06 | Pfam | 1-210 (270) | Show / Hide |
Range on Protein: 40-237 Range on HMM: 1-210/270 Sequence Identity: 21% (46 aa) YRELEQIGKGTSGTVFLVKSK---QDKKFYIAKKIILTNLNEQE--RQAVEQELILLKKL-KHPHIVGYKENFL---EPYYMIIIMEYCEQGDLSFHIKQ . ....|.| |.|.. . | ...| | |.. . ... |.. .|. ..|.| .||.|| . . || ...|.|||.. ||| . .. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK KLKENDHFPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSSGSIKLGDFGISKVL--HSTA-DKAQTLIGTPYYLSPEVCENKPYTYQSDIWAL . ...... .|.. .| ..... ..|. |||. |. .|... .| .||| .. . .. |.. ..||. .. .| .||.|. HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF GCVLFEMCAL | ...|.. . GVLMWEIFTY |
|||||||||
Kinase | 2122.AA | TyrKc | 40-294 | 18 | 7.8e-17 | 49.51 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 40-294 Range on HMM: 1-280/280 Sequence Identity: 18% (55 aa) YRELEQIGKGTSGTVFLVKSKQDKKFYIAKKIILTNLNEQERQAVEQELILLKKL--KHPHIVGYKENFLEP-------YYMIIIMEYCEQGDLSFHIKQ . ....| | |.|.. . | | | . . |.. .|. ...|| .||.|| ... . |.|||.. ||| ... ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK KLKENDHFPENIILNWFIQLTMALDFIHEKHVLHRDVKSSNIFLTSSGSIKLGDFGISKVLHST--------ADKAQTLIGTP-----YYLSPEVCENKP . .. .. |.. .| ...|.|.. ||| |. ... . .| .||| |. ... .... |. ..||. . HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YTYQSDIWALGCVLFEMCAL----KHP-----FVSESLMALVVKIIREPNPNI--PNM----YSSDLNCLVQILLAKKPESRPRTKQILSFP .| .||.|. | ...|.. . . ....| . | | | | | .... . . . .||.||. ..| .. FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |