Gene 13547 (Tetrahymena)
13547
Sequence
Protein domains of 13547.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| REC | 13547.AA | REC | 9-124 | 19 | 4.1e-23 | 84.03 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 9-124 Range on HMM: 1-150/150 Sequence Identity: 19% (31 aa) IHVLVAEDD----NFQRLALI------DILTLCDYQ--------VTAVENGR-------LARDELLKAD-----------SNIDIVLLDLYMP------- ...|...|| .| .| ..|. .|. |... .|. | . | . . ...|....|. || MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG EMDGIELLLLMQEHEHLKRIPVIMMSFDNEQERVAYCIANGAKDYLVKPLRIQNVKGLA .||||||. .. |.||.. .. | . ... || ||..|| ... . GMDGIELCRRIR--------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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| Response_reg | 13547.AA | Response_reg | 11-125 | 25 | 4.5e-22 | 81.64 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 11-125 Range on HMM: 1-115/115 Sequence Identity: 25% (30 aa) VLVAEDDNFQRLALIDILT-LCDY-QVTAVENGRLARDELLKADSNIDIVLLDLYMPEMDGIELLLLM-QEHEHLKRIPVIMMSFDNEQERVAYCIANGA ||...|. .| .| ||. .| |.....|. | . . . . .|....|. ||.|||.||. . ..|. .|.||.. .. . . .. || VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--PDLIIMDINMPGMDGLELCRRIRRQHP-HPQTPIIMCTAHGDEDDAVEALQAGA KDYLVKPLRIQNVKGLAK ||..|| .. . .. NDYITKPFDPDELHAAIR |
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| Kinase | 13547.AA | NEK | 146-401 | 41 | 1.5e-144 | 486.49 | In-house | 1-286 (286) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-286/286 Sequence Identity: 41% (120 aa) YKVIRMIGQGAGGSVELVQKRSDGQL-----FALKTISMKFMDDQQKKMAQ-QEITLLKVLVAPSIIRYYESFVEND--SIHIIMEYAK-EGALSDK--- |..|..||||. |.| .|...|||. ...| |.|. |....|..|| .|. .|| | | |..||.||.|.. ...|.|||. .| |..| YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS ITEHKQKGIPIDEETVLYFTAQIIISVLFMHSK-----NILHRDIKTQNLFLTKENI----VKLGDFGISKELG-TNANAKT-LVGTPYFMSPEVCSGEN | ..|||| ...||... . .|... . .||.. .|||||||.||.||||.|. ||.|||||||.|. |. |.| .|||||.||||||... IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP YGQKADIWAIGCTLYEMVML--KRPFDND--NLNILFNKIRFE-APPPLHEN--TSTEIRMLITFMLQKDPVKRPSVWDLAKIPII |..|.|||..|| ||||..| |.||. . |.. |..||. . .||.... |.. ..||..|||||| .|||.... . |.| YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | 13547.AA | NEK8 | 146-401 | 40 | 9.20000000001e-108 | 308.75 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-278/278 Sequence Identity: 40% (114 aa) YKVIRMIGQGAGGSVELVQKRSDG--QLFALKTISMKFMDDQQKKMAQQEITLLKVLVAPSIIRYYESFVENDSIHIIMEYAKEGALSDKITEHKQKGIP | || .|.|| |.. | ...|. .| .| | | |. . ||| || .|. | | || ||..| |. . | |||| | | ..| .|... YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMI--QHQQNKL IDEET-----------------VLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKE-NIVKLGDFGISKELGTNANAKT---LVGTPYFMSPEVCSGEN ||. .| . |. . | .||..||||||.|||| |.|. ..||.|||||||...| . | .||||| |||| |.| FEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKP YGQKADIWAIGCTLYEMVMLKRPFDNDNLNILFNKIRF-EAPPPLHENTSTEIRMLITFMLQKDPVKRPSVWDLAKIPII | || |.||.|| |||| ||| |. .|| | .|| | |. . | | |||.. ||.|| .|||. . . | . YNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC |
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| Kinase | 13547.AA | S_TKc | 146-401 | 30 | 9.2e-87 | 295.46 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-231/231 Sequence Identity: 30% (83 aa) YKVIRMIGQGAGGSVELVQKRSDGQLFALKTISMKFMDDQQKKMAQQEITLLKVLVAPSIIRYYESFVENDSIHIIMEYAKE--GALSDKITEHKQKG-- |...| ||.|| |.| .......|...|.| |. .....|| .|| | |...|..|.. |.....|||. | | | | ... .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR IPIDEETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKENIVKLGDFGISKELGTNANAKTLVGTPYFMSPEVCSGENYGQ-KADIWAIGCTLYEMV |..| .. ....||. . ..||..|.|||.| .|..|.. .|..|||....| .|..|||..|.|||. || |.|.|..||.||||. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML MLKRPFDNDNLNILFNKIRFEAPPPLHENTSTEIRMLITFMLQKDPVKRPSVWDLAK-------IPII . ||. ... .|.||. | | . .| .||||| |||.. .. . | . CGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 13547.AA | NEK1 | 146-401 | 37 | 5.8e-84 | 285.26 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-276/276 Sequence Identity: 37% (103 aa) YKVIRMIGQGAGGSVELVQKRSDGQLFALKTISMKFMDDQQKKMAQQEITLLKVLVAPSIIRYYESFVENDS--IHIIMEYAKEGALSDKITEHKQKGIP | .|..||.|. | . ||....|||....| |. | .. . . | .|... | |..|.|||.|| . |.|||. | | || . | || . YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL IDEETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLT--KEN---------------IVKLGDFGISKEL-GTNANAKTLVGTPYFMSPEVCSGENYGQ . | . . . || . . ..|...|||||||.||.||| | .||||||||.. | | . |.| .|||| ||| | | . FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN KADIWAIGCTLYEMVMLKRPFDNDNLNILFNKIRFEAPPPLHENTSTEIRMLITFMLQKDPVKRPSVWDLAKIPII | |||. || ||| . ||.||. |. | .|| ||. |.|.. |.. |....| |||| .. . |.| KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI |
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| Kinase | 13547.AA | NEK4 | 146-401 | 40 | 1e-80 | 274.48 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-257/257 Sequence Identity: 40% (104 aa) YKVIRMIGQGAGGSVELVQKRSDGQLFALKTISMKFMDDQQKKMAQQEITLLKVLVAPSIIRYYESFVENDS--IHIIMEYAKEGALSDKITEHKQKGIP | .. .|.| | | ||..| |. . .| . .| . ...| | .|. || | | |. | ||. . |.| . | | | .||. YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKL--KQQKNQF IDEETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKENIVKLGDFGISKELG-TNANAKTLVGTPYFMSPEVCSGENYGQKADIWAIGCTLYEMVML ..|. |. || . ..|| |.||||| ||||.|||| ||.|.||||||. | |||..||||.||||. . | | |||..|| .|||. | LEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITL KRPFDNDNLNILFNKIRFEAPPPLHENTSTEIRMLITFMLQKDPVKRPSVWDLAKIPII | || ..| | .| |||. | |... |. ||.| | ||||. |. . | | KHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI |
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| Kinase | 13547.AA | Pkinase | 146-391 | 27 | 7.8e-71 | 246.43 | Pfam | 1-283 (293) | Show / Hide |
Range on Protein: 146-391 Range on HMM: 1-283/293 Sequence Identity: 27% (79 aa) YKVIRMIGQGAGGSVELVQKRSDGQLFALKTISMKFMDDQQKKMAQQ--EITLLKVLVAPSIIRYYESFVENDSIHIIMEYAKEG----ALSDKITEHKQ |...| ||.|. |.| . .....|...|.|.|. . ...... . || ..| | | |.|.|..| ..|.|...|||. | |.| |. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W KGIPI--DEETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKENIV----KLGDFGISKE--LGTNANAKTLVGTPYFMSPEVCS-GENYGQKADIW .. .. .|... . ||. . ..||..|.|||.| .|... ... . |..|||..| . | ..|..|||..|.|||. |. ||.|.|.| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW AIGCTLYEMVMLKRPFDND------NLNILFNKIRFEAPPPLHENTS---------------------TEIRMLITFMLQKDPVKRPS ..||.||||. . ||... . . ....|. ..|.. .. .. | . .|. .|.||| |||. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIM-GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT |
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| Kinase | 13547.AA | Ciliate-E2 | 146-401 | 25 | 6.1e-69 | 235.36 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-365/365 Sequence Identity: 25% (96 aa) YKVIRMIGQGAGGSVELVQKRSDGQLF------------------ALKTISMKFMDDQQKKMAQQEITLLKVLV----------------APSIIRYYES ||.|..||||. ||| ..........| . | . || | .|... ||| ... . | ||..||. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FV--ENDSIHIIMEYAKEGALSDKITEHKQKG---IP----IDEETVLYFTAQII---------------ISVLFMHSKN-ILHRDIKTQNLFLTKENIV | ...| ..|||.. | | | | ..|.| |. ..|. ..|...||. . ..|||| |.||||| .|... . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLGDFGISKELGTN--------------------------------ANAKTLVGTPYFMSPEVCSGEN---------YGQKADIWAIGCTLYEMVMLKRP |. |||.||.. .. ..|..|||..|.||. .|.. |. |.|||..|..||||.. |.| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FDNDNLNILFNKIRFEAPPP------------LHENTSTEIRMLITF----MLQKDPVKRPS-VWDLAKIPII | .|. .||.| | . ... | | || |||||| ||.. ... . |.. F---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 13547.AA | STE | 146-401 | 25 | 2.7e-67 | 229.9 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-359/359 Sequence Identity: 25% (92 aa) YKVIRMIGQGAGGSVELVQKRS---------------DGQLFALKTISMKFMD---------------DQQKKMAQQEITLLKVLV--APSIIRYYESFV .. |..||.||.|.| . .. |...| | .... . ..... ..|| ..| . | |..|| ... WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF EN-------DSIHIIMEYAKEGALSDKITEHKQKGIPID----------EETVLYFTAQIIIS-VLFMHSKNILHRDIKTQNLFLTKENIVKLGDFGISK . |...|.||| | |.| | . . .| | . |. . |.. ||. . ||..| ||||| .| .| ||| |||... KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG ELG----------------TNA-NAKTLVGTPYFMSPEVCSGEN------YGQKADIWAIGCTLYEMVMLKRPF-DNDNLNILFNKIRF----------- | |.. . .|.|||| .|.||| .... |. |.||| .|||. ||. | |. | .. .|.... QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ---EAPPPLHENTS-------------------TEIRMLITFMLQKDPVKRPSVWDLAK--IPII . |||| ...| | . | ||||| |||.. .| | | | IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | 13547.AA | Ciliate-E2-Unclassified | 146-401 | 23 | 2e-65 | 223.65 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 146-401
Range on HMM: 1-352/352
Sequence Identity: 23% (84 aa)
YKVIRMIGQGAGGSVELVQKRSDGQLFALKTISMKFMDDQQKKMA-----QQEITLLKV----------------LVAPSIIRYYESFVENDS--IHIIM
||.|. ||||. |.| ..|.....|..|.|... . ...|...| ...... . | |....... ....| | |.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
EYAKEGALSDKIT-------------EHKQKGIPIDEETVL-----YFTAQIIISVLFMHSKN-ILHRDIKTQNLFLTKEN---IVKLGDFGISKELGTN
||.. | |.. |. ...... ..|. .. ...|||. ..|.|| |.||||| .|....... .|. ||||||....|
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
----------------ANAKTLVGTPYFM----SPEVCSGENYG----QKADIWAIGCTLYEMVMLKRPFDNDNLNI----------------LFNKI-R
...| .|||..| .||| |.||. |.|||. |. ||||.. ..||. | .. |...|
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
FEAPPPLHEN------TSTEIRMLIT----FMLQKDPVKRPSVWDLAKIPII
. | ... | | .|. ||.|.| ||.. ... . |..
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 13547.AA | CAMK | 151-392 | 21 | 7.3e-64 | 204.39 | In-house | 1-416 (425) | Show / Hide |
Range on Protein: 151-392
Range on HMM: 1-416/425
Sequence Identity: 21% (90 aa)
MIGQGAGGSVELVQKRSDG------------QLFALKTISMKFMD--------------------------DQQKKMAQQEITLLKVLV-------APSI
.|.|. | | |.. .... | .| | |. | .. .. .|. ..|| ..| | | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IRYYESFVE-------------------NDSIHIIM---EYAKEGAL----SDKITEHKQKG-----------IPIDEETVLYFTAQIIISVLFMHSKNI
|. || . .. ....| ||. | | |.|.||...| ..|. . .. ||. | ..||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
LHRDIKTQNLFLTKE-----------------NIVKLGDFGISKELGT------------------------NANAKTLVGTPYFMS-PEVCSGEN----
|||.| |. |.. | .|. ||| .... . || .|||..|. ||| .|.
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------YGQKADIWAIGCTLYEMVMLKRPFDND-------------NLNILFNKIR---FE-APPP--------------------LHENTSTEIR
||.|.|.|..|. || |. . ||. | |.. || ||. .. ||. | . |.| .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECK
MLITFMLQKDPVKRPSV
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DLIRKMLQVDPEKRMTI
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| Kinase | 13547.AA | NEK-Unclassified | 146-401 | 34 | 1.5e-60 | 199.09 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-258/258 Sequence Identity: 34% (91 aa) YKVIRMIGQGAGGSVELVQKRSDGQLFALKTISMKFMDDQQKKMAQQEITLLKVLVAPSIIRYYESFVENDSIHIIMEYAKEGALSDKITEHKQKGIPID | | .||| || | || . . || . ..|| | | .| | | |. | .|| || . .| | | .| | | |.| YDKITTLGQGGGGAVYLVRHQI-SKRHLVQQISKR----KKKKKRQNKIIILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFD EETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKENIVKLGDFGISKELG-TNANAKTLVGTPYFMSPEVCSGENYGQKADIWAIGCTLYEMVMLKR | . |.| | . |.. |.||| |.|| |||.. .| .||||||. . | |.| |||. .|||||| | . |.|. || .||| EGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEP PFDNDNLNILFNKIRFEAP------PPLHENTSTEIRMLITFMLQKDPVKRPSVWDLAKIPII || |. .. || . | || .|.|||.... .||| .. . | FFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI |
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| Kinase | 13547.AA | ULK | 146-401 | 25 | 1.7e-56 | 193.98 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-324/324 Sequence Identity: 25% (85 aa) YKVIRMIGQGAGG-SVELVQ-KRSD--GQLFALKTISMKFMDDQQKK--------MAQQEITLLKVLV------APSIIRYYESFVENDS--IHIIMEYA | .....|.|. | | |... .|..| | |..| | ..... . ..|| ..| | |...|. | . .. | ||||| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC KEGALSDKITEHKQ-----KGIPIDEETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKEN------------IVKLGDFGISKELGTN----ANAK | |.. | ..| .. . |. .. | ||. ..|..|| ||||| ||. ... . ..|..||| .| . | . NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ TLV------GTPYFMSPEVCS----GENYG-QKADIWAIGCTLYEMVMLKRPFDNDNLNILF-------------------NKIRFEAPPPLHENTSTEI |.| |||..|.|.. . ...|. |.||| .|| .|||. | || .. | .. ..|.| || . | |. TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPEC RMLITFMLQKDPVKRPSVWDLAKIPII . || |||.|. .| | .. ..|.. KDLIRRMLQYDEKDRISWEEIFNHPWF |
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| Kinase | 13547.AA | TyrKc | 146-401 | 19 | 6.4e-15 | 18.5 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 146-401 Range on HMM: 1-280/280 Sequence Identity: 19% (57 aa) YKVIRMIGQGAGGSVELVQKRSDGQLFALKTISMKFMDDQQKKMAQQEITLLKVL--VAPSIIRYYESFVEN-------DSIHIIMEYAKEGALSDKITE . ....| || | | . . . . | |.. ... .|. ... | | |.| | .. . . |.|||.. |.| | . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK HKQKGIPIDEETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKENIVKLGDFGISKELGTN----ANAKTLV-----GTP-----YFMSPEVCSGEN |. | . .. |.| || . ||||. |||. . | ......|| .||| |.... .. .. . |. |.||. HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YGQKADIWAIGCTLYEMVML-KRPFDN------DNLNILFNKIRFEAPPPLHEN-------TSTEIRMLITFMLQKDPVKRPSVWDLAKIPII . | |.|. | ...|. . . | . .| .. . . . .|. ... ..|. .... . || .||. ... . .. FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 13547.AA | Pkinase_Tyr | 146-342 | 24 | 2.7e-11 | 38.9 | Pfam | 1-210 (270) | Show / Hide |
Range on Protein: 146-342 Range on HMM: 1-210/270 Sequence Identity: 24% (52 aa) YKVIRMIGQGAGGSVELVQKR----SDGQLFALKTISMKFMDDQ--QKKMAQQEITLLKVL-VAPSIIRYYESFV-ENDS--IHIIMEYAKEGALSDKIT . ....|.|| |.| . . .... | |.. . |..| .... . |. ..| | | |.|.| . . .. | |.|||.. | | | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR EHKQKGIPIDEETVLYFTAQIIISVLFMHSKNILHRDIKTQNLFLTKENIVKLGDFGISKELGTNANAKTLVGT----PYF-MSPEVCSGENYGQKADIW .|. . |.. .. | . .|| . .|||. |||. . | .|..|.|| .||| .. . . . ... | . |.||. . . | |.| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW AIGCTLYEMVML . | ...|.. . SFGVLMWEIFTY |
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| DEP | 13547.AA | DEP | 467-542 | 15 | 0.000474 | 14.98 | SMART | 1-90 (90) | Show / Hide |
Range on Protein: 467-542 Range on HMM: 1-90/90 Sequence Identity: 15% (14 aa) LSSALSPYDQKISMFKVERNVINGKQLFQWIQQYYT------------NYNTSQVVEMLNELVEKKYLHHIA--GPLHQSDP-NSLYRFQF ... . .. ...|. .|. |..| .|. . . .. | . . ... .|.||. . .. .| ...|||| PETGVKMD-DHRWHMKTYPNCFTGSELVDWLMDHFEGQSNFCPTCTTFIHDREEAVHICQAMLDHGYIHHVNDWHKHTFQDDWQCYYRFQD |
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| DEP | 13547.AA | DEP | 485-540 | 19 | 0.000855 | 17.5 | Pfam | 15-75 (75) | Show / Hide |
Range on Protein: 485-540 Range on HMM: 15-75/75 Sequence Identity: 19% (12 aa) RNVINGKQLFQWIQ-QYYT--NYNTSQVVEMLNELVEKKYLHHIAGPLH-QSDP-NSLYRF .|. |... .|.. . . . . .. |.. ..|....|.||. . . .| ...||| PNCFTGSEAVDWLMNDCCEDFIIDREEAVHLGQDLMDHGYIHHVQDHHRGFQDSDHYFYRF |
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| DUF547 | 13547.AA | DUF547 | 666-719 | 34 | 1.4e-05 | 21.46 | Pfam | 51-112 (155) | Show / Hide |
Range on Protein: 666-719 Range on HMM: 51-112/155 Sequence Identity: 34% (22 aa) PFFSKSQDEFYYTIGNLQFTLDDIKHGIIRGNKTQ----------KLSSFKPFADNDSRKQFVL .||.. . ||.|. ..|||| |||.|.|. . .|||| | || ..| WFFFGPWNKAFYTVGGHKYSLDDIEHGILRPNRPHHRQWWKTLFSPHWKFKPFER-DWRK-YAL |
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