Gene 10577 (Tetrahymena)

10577

Species: Tetrahymena
Alias: 13, 10577, 92.m00119, PreTt10577, TTHERM_00641080
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: IRE

Sequence

Name Sequence Type Origin Length Description Download
10577.AA Protein None 838 None Fasta, JSON
10577.kin_dom Protein Kinase Domain None 231 None Fasta, JSON
10577.NA RNA None 2517 None Fasta, JSON

Protein domain

Protein domains of 10577.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10577.AA IRE 476-706 37 1.5e-124 420.08 In-house 18-292 (292) Show / Hide 
Range on Protein: 476-706
Range on HMM: 18-292/292
Sequence Identity: 37% (104 aa)

VNIGREIAVKQLLKDNKDLASKEIQMLIK---LQHKNIIKYYYFEETKDHILLGLEKCVGSISDLIDYANRKNKKK----SEQDLKALYNIKTDFFIKST
.|.....||||..|......|.|||||||    .|.|.|.||..||......|.||.|.||..|......|.|...    |....|...|......|...
WNGRIPVAVKQMQKEFNPFISREIQMLIKLESDNHPNVIRYYCQEEDDQFVYLALELCQGSLQDYVEQKKRNNFINSSNNSNNNNKNNNNNNNQWQIHIR

MKNTFKDCLEGLSYLHSQGVIHRDIKPENILIHY--------NKEIKLADFGLSKNISKTNVIFTN-----DIGTWGWRPLEQIDN---QPLTYNTDVFS
|....|.|..||..||||...|||.||.|||||.        |......||||.|........||.     ..|||||.|.|....   ...|...|.||
MWQLIKQCMNGLQHLHSQNIVHRDLKPHNILIHMNRPNQHGENNRFMISDFGLCKMLVEGRYSFTRNIRSGPTGTWGWHPPEMLQEFCQKRKTKSVDIFS

LGCVFYYIYTQGGHPFG-EYLRMEDETLK--------------------DLIQKMIHNDQSKRLTVKECLKHPYF
.||||||..|.|.|||| ..|......||                    |||..|||.|..||.|.||||.||.|
MGCVFYYVMTNGQHPFGNDKLHRQANILKGKYNLDQLKHHNHWHIVIACDLIHQMIHHDPQKRPTIKECLNHPFF
Kinase 10577.AA Ribonuc_2-5A 711-837 30 2.6e-49 174.91 Pfam 1-137 (137) Show / Hide 
Range on Protein: 711-837
Range on HMM: 1-137/137
Sequence Identity: 30% (42 aa)

QKFSFICEFSDYIETFDTENKYSDLIEQQAKSLNVLEGNRWDKNVDKSLIQDTKVF-KF---YNYGQVKDLIRLIRNRKSHYHEL-SESSKDIVGDTLDD
....|.|..||..|..|...... | .....| .|.....|.|..||....| . . ..   |....|.||.|..||.| ||||. .|. |.|.||. |.
KRLRFLCDVSDRFEIEDRDPPSPILQALERTSRCVVGFGDWHKKIDKAFMDDMGKYYRKRKNYYGDSVRDLLRAMRNKKHHYHEMKPEEMKEILGDLPDG

MFNYFDERFPKLFIFMYYFS---QTQNWELLS--FKN
...||.||||.|....|..    .....|...  .|.
FLQYFTERFPHLLMHCYHVMQECHCEHEEHFHKYYKP
Kinase 10577.AA Ciliate-E2 437-706 21 1.4e-42 143.95 In-house 1-365 (365) Show / Hide 
Range on Protein: 437-706
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

INRNKVLGYGAQGTVIFEGTFQGNIQEQKIVFDLINIVYV-----NIGREIAVKQLLKDNKDLASKEIQMLI----------------KLQHKNIIKYYY
.. .|..| |..|.|      . . |......|  ....      . . ..|.|.. |...   ..||...                 .|.|.||||.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

FEE--TKDHILLGLEKCVG-SISDLIDYANRKNKKKSEQDLKALYNIKTDFFIKSTMK-------NTFKDCLEGLSYLHSQG-VIHRDIKPENILIHYNK
. .  ....| | .| | | .  |.|   . | ... |.| | .   .  ...|   .       . .   ...| ||||.. .|||||||||||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

EIKLADFGLSKNISKTNV-------------------------------IFTNDIGTWGWRPLEQIDNQP---------LTYNTDVFSLGCVFYYIYTQG
 ||..||||||.... |                                .| . .|| |  . | . ...          .|  |..|||...|.  . |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF-G

GHPFGEYLRMEDETLK--------------------------------DLIQK----MIHNDQSKRLT-VKECLKHPYF
 .||      ... ..                                |||.|    |.  |..||.|  ...|.||.|
KPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 10577.AA S_TKc 437-706 25 7.1e-41 143.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 437-706
Range on HMM: 1-231/231
Sequence Identity: 25% (74 aa)

INRNKVLGYGAQGTVIFEGTFQGNIQEQKIVFDLINIVYVNIGREIAVKQLLKDNKDLASKEIQMLIKLQHKNIIKYYYFEETKDHILLGLEKCVG---S
    ...| || |.| . ..  .                   ||. |.|..     . . .|||.| | .|.||.|.|.. .. ||. . .| | |   .
YEILRKIGKGAFGKV-YKCRHKK------------------TGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGD

ISDLIDYANR--KNKKKSEQDLKALYNIKTDFFIKSTMKNTFKDCLEGLSYLHSQGVIHRDIKPENILIHYNKEIKLADFGLSKNISKTNVIFTNDIGTW
  |.|.  .|  .... .| . . .                ..  ...| |.||.|.||||.||||||.    .||..||||.. .       |  .|| 
LFDYIKKRGRHGLRFPFPE-HARFY----------------MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTP

GWRPLEQIDNQPLTY-NTDVFSLGCVFYYIYTQGGHPFGEYLRME------DETLKDLIQKMIHNDQSKRLTVKECLK-------HPYF
 ... | .   . ..   |. |.||..|  .. |  ||     ..      .. .||.|.|. . | .||.|. |.|.       ||.|
WYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 10577.AA Pkinase 577-706 30 2.6e-37 133.0 Pfam 118-293 (293) Show / Hide 
Range on Protein: 577-706
Range on HMM: 118-293/293
Sequence Identity: 30% (54 aa)

LEGLSYLHSQGVIHRDIKPENILIHYNKEI----KLADFGLSKNI-SKTNVIFTNDIGTWGWRPLEQID-NQPLTYNTDVFSLGCVFYYIYTQGGHPFG-
|.|| |.||.|.||||.|||||||. | .|    |..||||.| .    |. .|   || .... | |  .|. ..  |..|.||..|. .. |  ||  
LRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPG

-----------EYLRMED-------------------------------ETLKDLIQKMIHNDQSKRLTVKECLKHPYF
            . |  .                               |..||.| .... | .||.| ...|.||.|
HCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 10577.AA Ciliate-E2-Unclassified 480-706 21 1.7e-34 117.06 In-house 36-352 (352) Show / Hide 
Range on Protein: 480-706
Range on HMM: 36-352/352
Sequence Identity: 21% (73 aa)

REIAVKQLLKDNKDLASKEIQMLIK------------------LQHKNIIKYYYFEETKDHILLGLEKCVGSISDLIDYAN----------------RKN
.....|| .. . ..  ....| .|                  ..| .|.|..| ...|..| . .|.| |   ||..| .                ...
QIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGG--DLWQYIKKRKKQKQKGNDLFHNMKQR

KKKSEQDLK---ALYNIKTDFFIKSTMKNTFKDCLEGLSYLHSQG-VIHRDIKPENILIHYNK---EIKLADFGLSKNISKTNVIFTND-----------
|. .||  |   |              |. |.  |.||.|||... .|||||||||||.. |.   .||..|||.||.. . | .  ..           
KIFTEQQAKYKKA--------------KFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQ

-----IGTWGWR----PLEQIDNQPLT----YNTDVFSLGCVFYYIYTQGGHPFG---------------------EYLRME------------------
     .|| .      . | ...|       |  |..|||...|.. ..  .||.                     ....                    
MMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKH

-DETLKDLIQ----KMIHNDQSKRLTVKECLKHPYF
 ... ||.|.    ||. ....||.| .. |.||.|
WSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 10577.AA STE 477-706 21 2.2e-34 118.85 In-house 37-359 (359) Show / Hide 
Range on Protein: 477-706
Range on HMM: 37-359/359
Sequence Identity: 21% (72 aa)

NIGREIAVKQLL--------------------KDNKDLASKEIQMLIKLQ--HKNIIKYYYFEETK-------DHILLGLEKCV-GSISDLIDYANRKNK
. |. .|.||.                     .....   |||... |..  |.||.|||  .. .       |.. . .| .  ||..|.|.    ..|
ETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGK

--KKSEQDLKALYNIKTDFFIKSTMKNTFKDCLEG-LSYLHSQGVIHRDIKPENILIHYNKEIKLADFGLSKNISK---------------TNVIFT-ND
  ... |          ..|  |  .   ...|.| |.||||...||||||| |||.     .||.|||.......               |..  .  .
PLNHNRQ-------H-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTF

IGTWGWRPLEQIDN------QPLTYNTDVFSLGCVF---------YYIYTQG---------GHPF----------GEYLRMED-----------------
.||  |   | |..      .. ..  |. ||||.          .  ..           .|..          |.  . .|                 
VGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTY

-----ETLKDLIQKMIHNDQSKRLTVKECLK--HPYF
     . .|| |.|    | .|| |... ||  || .
PHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 10577.AA CMGC 479-662 19 1.2e-25 80.45 In-house 38-330 (513) Show / Hide 
Range on Protein: 479-662
Range on HMM: 38-330/513
Sequence Identity: 19% (59 aa)

GREIAVKQLLKD-NKDLAS-------------KEIQMLIKLQ-----------------HKNIIKYYYFEETKD-----------------HILLGLEKC
....|.| . .. ... |               ||..| .|.                 |.||.| |..  .|.                 |. |  | .
NEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYM

VGSISDLIDYANR-----KNKKKSEQD---------LKALYNIKTDFFIKSTM---KNTFKDCLEGLS--YLHSQG--VIHRDIKPENILIHYNKE----
  .  ..|.  ..     .... ||           .           ||. |   .  ..  |.||   |.||..  .||||.|||||||  |.|    
DHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPP---------HNIKYFMIHIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITR

----------------IKLADFGLSKNISKT---------------------NVIFTNDIGTWGWRPLEQIDNQPL----------TYNTDVFSLGCVFY
                .|..||||.. ...                      |  .|... |   |. | . . .           |.  |. |.||.|.
MMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFA

YIYT
 .||
EMYT
Kinase 10577.AA TKL 574-704 20 2e-24 84.87 In-house 139-364 (364) Show / Hide 
Range on Protein: 574-704
Range on HMM: 139-364/364
Sequence Identity: 20% (46 aa)

KDCLEGLSYLHSQG--------VIHRDIKPENILIHYNKE--------------IKLADFGLSKNISKTNV-------------------IFTNDIGTWG
.|.  |..||||..        .||||.|..|||.. | .              .|..|||||...|...                       . .|| .
LDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPR

WRPLEQIDNQ----------------PLTYNTDVFSLGCVFYYIYT--QGGHPFGEYLRM---------------------------------------E
| . | ...|                . .  .||.| | |.. |.|  .   |. .|  |                                        
WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDC

DETLKDLIQKMIHNDQSKRLTVKECLKHP
.. .|.|.|.  . | .||.. .|.||. 
PPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 10577.AA Ciliate-E2a 497-658 28 3e-24 68.31 In-house 48-207 (275) Show / Hide 
Range on Protein: 497-658
Range on HMM: 48-207/275
Sequence Identity: 28% (50 aa)

KEIQMLIKLQHKNIIKYYYFEETKDHILLGLEKCVG-SISDLIDYANRKNKKKSEQDLKALYNIKTDFFIKSTMKNTFKDCLEGLSYLHSQGVIHRDIKP
.||. . .| |.|||| | . |..... | .| | | .  | | .  | ...              .. |.. |.. .    .||.|.|.....|||.||
NEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE--------------IQEICDIMQQLLW---QGLHYMHQRNIMHRDLKP

ENILIH-------YNKEIKLADFGLSKNI--SKTNVIFTNDIGTWGWRP------LEQIDNQPLTYNTDVFSLGCVFY
||||.        .|..||..||||...|   . ...|.   || |  .       | . ..  ..  |..|.|..||
ENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQK-CGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFY
Kinase 10577.AA CAMKL 577-614 52 2.9e-20 61.24 In-house 137-176 (297) Show / Hide 
Range on Protein: 577-614
Range on HMM: 137-176/297
Sequence Identity: 52% (21 aa)

LEGLSYLHSQGVIHRDIKPENILIHYNK--EIKLADFGLS
.....|.||.|..||||||||||. .|.   ||..|||.|
VSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFS
Kinase 10577.AA CAMK 577-619 30 1.1e-19 59.39 In-house 189-248 (425) Show / Hide 
Range on Protein: 577-619
Range on HMM: 189-248/425
Sequence Identity: 30% (18 aa)

LEGLSYLHSQGVIHRDIKPENILIHYNK-----------------EIKLADFGLSKNISK
.... |.||....|||.||||||. .|.                  ||..|||... . .
CSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDP
Kinase 10577.AA Ciliate-E2c 577-625 52 4.4e-18 60.04 In-house 124-172 (310) Show / Hide 
Range on Protein: 577-625
Range on HMM: 124-172/310
Sequence Identity: 52% (26 aa)

LEGLSYLHSQ-GVIHRDIKPENILIHYNKEIKLADFGLSKNISKTNVIFT
. .. |||.. ...|||||||||||| | .||.||||.|| .   |. .|
ISAFKYLHKEKNIFHRDIKPENILIH-NGMIKIADFGFSKICQDDNIQNT
Kinase 10577.AA TyrKc 437-713 21 6.7e-14 2.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 437-713
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

INRNKVLGYGAQGTVIFEGTFQGNIQEQKIVFDLINIVYVNIGREIAVKQLLKDNKDLASKEIQMLIKL--QHKNIIKYYYFEETK-------DHILLGL
|  .|.|| || |.| ..||                       .. ||| | .| .    .|.... ||  .|.||.. |    ..       . ... .
ITLGKKLGEGAFGEV-YKGTWK---------------------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM

EKCVGSISDLIDYANRKNKKKSEQDLKALYNIKTDFFIKSTMKNTFKDCLEGLSYLHSQGVIHRDIKPENILIHYNKEIKLADFGLSKNISKT-------
| . .   || ||  ||...|               .  ... .   .  .| .||||...||||.   |.|.. |. .| .|||||..|          
EYMPH--GDLKDY-LRKHRPK---------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESK

NVIFTND-IGTWG-----WRPLEQIDNQPLTYNTDVFSLGCVFYYIYTQGGHPFGEYLR--MEDETLKDLIQKMIHNDQSKR--------------LTVK
 .. .    |. .     | ..| |.    |  .||.| | . . |.| |. |  .     |... .  ....    .| .                  |
DYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMK

ECLKH-----PYFWNTLQKF
.| ..     | |..  ..|
QCWHEDPEDRPTFSEIHECF
Kinase 10577.AA CMGC 666-706 30 1.8e-12 36.39 In-house 466-513 (513) Show / Hide 
Range on Protein: 666-706
Range on HMM: 466-513/513
Sequence Identity: 30% (15 aa)

HPFGEYLR--------MEDETLKDLIQKMIHNDQSKRLTVKECLKHPYF
..|... .        ..|. . ||..|| . | .||.|....|.||||
EKFKSH-KFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 10577.AA Ciliate-E2a 680-706 48 1.3e-11 30.49 In-house 249-275 (275) Show / Hide 
Range on Protein: 680-706
Range on HMM: 249-275/275
Sequence Identity: 48% (13 aa)

KDLIQKMIHNDQSKRLTVKECLKHPYF
|||..||   | .||.| ...|.||.|
KDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 10577.AA CAMK 676-706 42 1.8e-10 29.25 In-house 388-425 (425) Show / Hide 
Range on Protein: 676-706
Range on HMM: 388-425/425
Sequence Identity: 42% (16 aa)

DE-------TLKDLIQKMIHNDQSKRLTVKECLKHPYF
||         ||||.||   | .||.|...||.|| .
DEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 10577.AA Pkinase 474-554 26 3.1e-08 30.21 Pfam 19-111 (293) Show / Hide 
Range on Protein: 474-554
Range on HMM: 19-111/293
Sequence Identity: 26% (25 aa)

VYVNIGREIAVKQLLKDNKDLASK-------EIQMLIKLQHKNIIKYYYFEETKDHILLGLEKCVGSISDLIDYA----NRKNKKK--SEQDLK
. .. |.. |||.. |....   .       |||.. .|.|.||...|.. |.|||| . .| | |  . ..| .     .....   ||...|
HHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECK
Kinase 10577.AA IRE 440-459 45 9e-08 22.58 In-house 1-20 (292) Show / Hide 
Range on Protein: 440-459
Range on HMM: 1-20/292
Sequence Identity: 45% (9 aa)

NKVLGYGAQGTVIFEGTFQG
|..||.|. ||. |.|...|
NNILGRGCNGTLVFKGIWNG
Kinase 10577.AA Pkinase_Tyr 578-617 42 1.7e-07 26.05 Pfam 122-161 (270) Show / Hide 
Range on Protein: 578-617
Range on HMM: 122-161/270
Sequence Identity: 42% (17 aa)

EGLSYLHSQGVIHRDIKPENILIHYNKEIKLADFGLSKNI
.|..||.|.. ||||.   |.|.. |. .| .||||.. |
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase 10577.AA CAMKL 676-706 32 2.2e-07 19.44 In-house 268-297 (297) Show / Hide 
Range on Protein: 676-706
Range on HMM: 268-297/297
Sequence Identity: 32% (10 aa)

DETLKDLIQKMIHNDQSKRLTVKECLKHPYF
.  ..|||.||   . .|| |... ..|| .
S-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 10577.AA CAMK 442-532 17 2.4e-07 18.95 In-house 1-144 (425) Show / Hide 
Range on Protein: 442-532
Range on HMM: 1-144/425
Sequence Identity: 17% (28 aa)

VLGYGAQGTVIFEGTFQGNIQEQKIVFDL-IN-------IVYVNIGREIAVKQLLKD-------------------------------NKDLASKEIQML
.|| |. |.|               ...   .       | |.| |.. |.| . |.                               ...   .||...
TLGRGSFGKVK-------------LCIHKNTTGKERVHHI-YTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIM

IKLQ-------HKNIIKYYYFEE------------TKDH--------ILLGL---EKCVG
 |||       |.|||| | . |            | ..        . . .   | | |
KKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSG
Kinase 10577.AA CAMKL 479-532 27 4e-06 15.32 In-house 25-105 (297) Show / Hide 
Range on Protein: 479-532
Range on HMM: 25-105/297
Sequence Identity: 27% (22 aa)

GREIAVKQLLKDNKDL------------------ASKEIQMLIKLQ---HKNIIKYYYFEETKDH------ILLGLEKCVG
|.. |.| . |. . .                    .||| . .|.   |.|||| |   ||..|      | | .| | |
GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSG
Kinase 10577.AA Ciliate-E2c 671-706 30 9e-06 16.23 In-house 275-310 (310) Show / Hide 
Range on Protein: 671-706
Range on HMM: 275-310/310
Sequence Identity: 30% (11 aa)

YLRMEDETLKDLIQKMIHNDQSKRLTVKECLKHPYF
|. . .. .|.||.||.  | .||.  .|   |. .
YEQNISQEVKQLIHKMLQVDEEKRIDWDEIFNHECI
Kinase 10577.AA Ciliate-E2c 488-530 39 2.4e-05 14.77 In-house 54-96 (310) Show / Hide 
Range on Protein: 488-530
Range on HMM: 54-96/310
Sequence Identity: 39% (17 aa)

LKDNKDLASKEIQMLIKLQHKNIIKYYYFEETKDHILLGLEKC
.|| |  ...||.|. .. |..|||.| .  |. || | .| |
EKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYC
Kinase 10577.AA PUG 772-826 27 4.5e-05 24.09 SMART 1-66 (66) Show / Hide 
Range on Protein: 772-826
Range on HMM: 1-66/66
Sequence Identity: 27% (18 aa)

GQVKDLIRLIRNRKSHYHEL--------SESSKDIVGDTLDDMFNYFDERFPKLFI---FMYYFSQ
  |.||.|..|| . |..|.         .  |  .|.  ..  .|| ..||.| |     | | .
ESVRDLLRYMRNIYHHPREEKFRKIRMENKAFKEKMGQVPGGFECYFTCGFPDLMIHAWEHYFFCK
Kinase 10577.AA TKL 479-514 18 0.000346 10.99 In-house 26-91 (364) Show / Hide 
Range on Protein: 479-514
Range on HMM: 26-91/364
Sequence Identity: 18% (12 aa)

GREIAVKQLLKDNK------------------------------DLASKEIQMLIKLQHKNIIKYY
|...|||.. ..|                               .   .|| |...|.| ||....
GKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFM
Kinase 10577.AA Ciliate-E2c 437-451 53 0.004861 6.6 In-house 1-15 (310) Show / Hide 
Range on Protein: 437-451
Range on HMM: 1-15/310
Sequence Identity: 53% (8 aa)

INRNKVLGYGAQGTV
|.||. || | .|.|
IDRNNILGSGSYGKV
Kinase 10577.AA Pkinase_Tyr 483-514 27 0.058866 7.25 Pfam 32-70 (270) Show / Hide 
Range on Protein: 483-514
Range on HMM: 32-70/270
Sequence Identity: 27% (11 aa)

AVKQLLKDNKDLAS-------KEIQMLIKL-QHKNIIKYY
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AVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY