Gene 13029 (Tetrahymena)

13029

Species: Tetrahymena
Alias: PreTt13029, 459, TTHERM_00058440, 4.m00428, 3707.m00073, 13029
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E5

Sequence

Name Sequence Type Origin Length Description Download
13029.AA Protein None 655 None Fasta, JSON
13029.kin_dom Protein Kinase Domain None 96 None Fasta, JSON
13029.NA RNA None 1968 None Fasta, JSON

Protein domain

Protein domains of 13029.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13029.AA Ciliate-E5 192-312 38 1.1e-72 235.84 In-house 84-271 (271) Show / Hide 
Range on Protein: 192-312
Range on HMM: 84-271/271
Sequence Identity: 38% (73 aa)

TDLKQFMKDKLANNIWMSKKYIYETCLQLVLGLKAIHNKNVLHLDIKPANLLLGLDLKWKYTDLGVS---------KNVDDERD----------------
.||..... ..  . | .  .||. ||||| ||..||.||..||||||||.|||.|.||||.|.|.|         |.|...|.                
CDLHTYLNKIIYQMKWQKHQDIYQICLQLVKGLQDIHQKNIIHLDIKPANILLGYDNKWKYIDMGISRKFKHVVRDKQVSEQRQNSSETIEENMIKFIKI

-------------------------HTVNLKGITACYSSPEQYQLYQFQS-----------------NKKITKQCDIYSLGVVFMELT
                         ||.||||.|.|||||||||.|..|.                 .||||||.||||||.||.|||
IPYFFQREYPKLHNKNRKKLRYQIPHTCNLKGFTQCYSSPEQYQCYHNQMFYILIRNLPDIKYIQSFKKKITKQSDIYSLGIVFLELT
Kinase 13029.AA Ciliate-A1 204-371 30 4.6e-43 144.45 In-house 94-301 (301) Show / Hide 
Range on Protein: 204-371
Range on HMM: 94-301/301
Sequence Identity: 30% (64 aa)

NNIWMSKKYIYETCLQLVLGLKAIHNKNVLHLDIKPANLLLGLDLKWKYTDLGVSKNVDDER------------------DHTVNLKGITACYSSPEQYQ
.| .|.|  ||| |.|.. |. .|| .|.||.|.|| | |.. | |||  ||| ||     .                   ||.  || .  | ||||||
QNDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLGMSKQLEQNQDCCDDVNGCSFSKQVNKHYHTCK-KGGNLYYMSPEQYQ

LYQ---FQSNKKITKQCDIYSLGVVFMELTG-----------VDIRKKWVIKQK----------IRQKPFDKYLNPEFQEFNDAVLKNMMQYNANQRIQL
..      .  || || |.||||.....|..           | |     .  .          | .  |    .|.| | .  ... ||||. |.|..|
MHYRDQMFIENKIYKQSDMYSLGCIICFLCYKEDSHPYVGTIVNIFGNNMQNDQSIHFCKSVNAIKKIIFPPMQEPRFEELQ-NLIFKMMQYEPNNRCSL

DELEVILKNL
...   |. .
QQCIDCLYIF
Kinase 13029.AA Ciliate-B2 219-305 37 1e-27 62.16 In-house 112-197 (197) Show / Hide 
Range on Protein: 219-305
Range on HMM: 112-197/197
Sequence Identity: 37% (33 aa)

QLVLGLKAIHNKNVLHLDIKPANLLLGLDLKWKYTDLGVSKNVDDERDHTVNLKGITACYSSPEQYQLY-QFQSNKKITKQCDIYSLG
||. ||  .. .|.|||||||.| |.    . .|.| |.|       .  .. || |  | |||| .      .  .|  | ||||.|
QLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKK--DNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 13029.AA Ciliate-E1 175-302 27 1.4e-20 64.02 In-house 60-202 (202) Show / Hide 
Range on Protein: 175-302
Range on HMM: 60-202/202
Sequence Identity: 27% (39 aa)

VISQLIKNKPYIDYFKDTDLKQFMKDKLA-------------NNIWMSKKYIYETCLQLVLGLKAIHNKNVLHLDIKPANLLLGLDLKWKYTDLGVSKNV
.| .... . || ... . ...  ||.|              |..... . . .   ||. || ..|..|..|.||||.|.|   . . .|.|.|.||. 
IIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFL

DDERDHTVNLKGITACYSSPEQYQ---LYQFQSNKKITKQCDIY
  . ..... || | .|..||||.   . . . |.||... |||
KNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY
Kinase 13029.AA Ciliate-E5 76-132 39 1.1e-19 60.58 In-house 1-58 (271) Show / Hide 
Range on Protein: 76-132
Range on HMM: 1-58/271
Sequence Identity: 39% (23 aa)

FLDQTILGKGGNGYVLKGIDAF-NYKVAIKVLKCETEEQYLQNQYEYENMKQCNSKYV
..   ||||||.| |.|| .   .. .|||..|| . .|. .|| |....||.||...
IIENQILGKGGSGMVMKGCSEWNDKPIAIKIMKCKNQKQCEDNQREFNILKQFNSPHI
Kinase 13029.AA Ciliate-E3 209-312 37 2.2e-19 57.34 In-house 101-202 (202) Show / Hide 
Range on Protein: 209-312
Range on HMM: 101-202/202
Sequence Identity: 37% (40 aa)

SKKYIYETCLQLVLGLKAIHNKNVLHLDIKPANLLLGLDL---KWKYTDLGVSKNVDDERDHTVNL-KGITACYSSPEQYQLYQFQSNKKITKQCDIYSL
..  ||. | |.. |. ||| ||. | |||| | |..  .     |  |.| ||    .  ||  .  | |  |..||| .  |      | |  |.||.
TQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGESKQLRKNKGHTHTQYQGWTPFYAAPEQNDQQQ------ISKESDYYSV

GVVFMELT
|.||..| 
GAVFCQLC
Kinase 13029.AA Ciliate-E2 187-308 22 3.6e-16 51.97 In-house 114-286 (365) Show / Hide 
Range on Protein: 187-308
Range on HMM: 114-286/365
Sequence Identity: 22% (41 aa)

DYFKDTDLKQFMK--DKLANNI---------WMSKKYIYETCL-----------QLVLGLKAIHNKN-VLHLDIKPANLLLGLDLKWKYTDLGVSKNVDD
.|..  ||....|  .|  |..            |..... .            ...|.|. .|.|| ..| |||| |.|.      | .|.| ||..||
EYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDD

ERDHTVNLKGI-------------------------------TACYSSPEQYQL--YQFQSNKK-ITKQCDIYSLGVVF
... .   | .                               |. | .|| ..   |. |...|  ...|||.||||..
DNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase 13029.AA C8 194-308 30 6.8e-15 48.22 In-house 106-226 (226) Show / Hide 
Range on Protein: 194-308
Range on HMM: 106-226/226
Sequence Identity: 30% (38 aa)

LKQFMKDKLANNIWMSKKYIYETCLQLVLGLKAIHNKNVLHLDIKPANLLLGLDLKW----KYTDLGVSKNVDDERDHTVNLK----GITACYSSPEQYQ
|||. ...  ..  .||.   .  .|.. |.  || ||..| |||| |.|. || .     |  |.|..  | ....|    |    | |  |. ||. .
LKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCG-TWAYFAPEIEK

LYQFQSNKKITKQCDIYSLGVVF
  | . .|. ..| |..|.|.| 
K-QDNQYKQYRIQSDLFSVGLVL
Kinase 13029.AA S_TKc 76-372 16 7.2e-15 41.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 76-372
Range on HMM: 1-231/231
Sequence Identity: 16% (52 aa)

FLDQTILGKGGNGYVLKGIDAF-NYKVAIKVLKCETEEQYLQNQYEYENMKQCNSKYVQIKYLIPHNGALLKCLLLIFLKISINKFPNISLPIHSQVLSL
.    ..|||. | | |...   . .||||..|                                           |   |.| |        |  .  |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------------------EHIRREIQILKK------HHPNIVKL

VISQLIKNKPYI--DYFKD--TDLKQFMKDKLA--NNIWMSKKYIYETCLQLVLGLKAIHNKNVLHLDIKPANLLLGLDLKWKYTDLGVSKNVDDERDHT
  .    .. |.  .|      ||....|..    .. ...   .   . |....|. .|.....| |.||.|.||      | .| |... .       
YDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------

VNLKGITACYSSPEQYQLYQFQSNKKITK-QCDIYSLGVVFMELTG----VDIRKKWVIKQKIRQKPFDKYLNPEFQEFNDAVLKNMMQYNANQRIQLDE
 .    |  | .||           . .|  ||..|.|... |.       .     .. .||.            .|. |  .....|.. ..|.   |
-TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-E

LEV-----ILKNLI
.        .   .
ALQDEWDIKCHPWF
Kinase 13029.AA STE 217-311 27 1.4e-14 48.04 In-house 157-261 (359) Show / Hide 
Range on Protein: 217-311
Range on HMM: 157-261/359
Sequence Identity: 27% (31 aa)

CLQLVLG-LKAIHNKNVLHLDIKPANLLLGLDLKWKYTDLGVSKNVDDERD----------------HTVNLKGITACYSSPEQYQLYQFQSN-KKITKQ
| |.. | |. .|.... | |||||| ||      | .| ||.....|. .                ..  . |    . .||  |  .   . |. . .
CRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQG-RDKGYDTK

CDIYSLGVVFMEL
|||.||| . .|.
CDIWSLGCTIIEM
Kinase 13029.AA Pkinase 217-311 22 4.6e-14 50.82 Pfam 114-205 (293) Show / Hide 
Range on Protein: 217-311
Range on HMM: 114-205/293
Sequence Identity: 22% (23 aa)

CLQLVLGLKAIHNKNVLHLDIKPANLLLGLDLKW----KYTDLGVSKNVDDERDHTVNLKGI--TACYSSPEQYQLYQFQSNKKITKQCDIYSLGVVFME
..|.. ||. .|.....| |.||.|.|.  .       | .| |..| .|    . . ....  |  | .||  .     ....... .|..|.|... |
MYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIR-----GGQYYGPKVDMWSCGCILYE

L
.
M
Kinase 13029.AA ULK 219-364 23 1.8e-13 43.43 In-house 138-323 (329) Show / Hide 
Range on Protein: 219-364
Range on HMM: 138-323/329
Sequence Identity: 23% (46 aa)

QLVLGLKAIHNKNVLHLDIKPANLLLGLDLK------------WKYTDLGVSKNVDDE---RDHTVNLK------GITACYSSPEQYQLYQFQ-SNKKIT
|.. |.|..| .|. | ||||.| |.  .               | .| | .| ||..    . ..  .      | |  | .|   |. | |  .|. .
QILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCG-TPLYMAP---QILQGQGEQKPYY

-KQCDIYSLGVVFMELTG--------VDIRKKWVIKQK----------IRQKPFDKY-------LNPEFQEFNDAVLKNMMQYNANQRIQLDEL
 . |||.|||..| |.              ... |..           |...|.. .       . ||....    .. |.||. ..||  .||
DYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDL----IRRMLQYDEKDRISWEEL
Kinase 13029.AA TKL 217-311 17 3e-13 44.08 In-house 138-282 (364) Show / Hide 
Range on Protein: 217-311
Range on HMM: 138-282/364
Sequence Identity: 17% (25 aa)

CLQLVLGLKAIHN--------KNVLHLDIKPANLLLGLDLK--------------WKYTDLGVSKNVD---DERDH---------------TVNLKGITA
.|.  .|.   |.        ....| |.|..|.|.  ...               | .|.| |....   .  |                | . .. | 
ALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTP

CYSSPEQYQLYQFQSNK----------KITKQCDIYSLGVVFMEL
.. .||  .  .. ..|          . ...||.|| |.|. |.
RWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI
Kinase 13029.AA Ciliate-A1 76-132 32 6.6e-13 40.22 In-house 1-59 (301) Show / Hide 
Range on Protein: 76-132
Range on HMM: 1-59/301
Sequence Identity: 32% (19 aa)

FLDQTILGKGGNGYVLKGIDAFNYK--VAIKVLKCETEEQYLQNQYEYENMKQCNSKYV
..    ..||. | |.. .|  | |  ...|...| . |||. |  ||  .|| |. .|
YHVVQLIDKGSFGVVMRAYDIQNQKKYLCCKIIICTNFEQYKNNIQEYRKCKQINHNNV
Kinase 13029.AA TyrKc 76-368 16 1e-06 -115.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 76-368
Range on HMM: 1-280/280
Sequence Identity: 16% (55 aa)

FLDQTILGKGGNGYVLKGIDAFNYKVAIKVLKCETEEQYLQNQYEYENMKQC--NSKY-VQIKYLIPHN-------GALLKCL-------LLIFLKISIN
     .|| |  | | ||.    ..||.|.|| ...|  ..   | . |..   . .  |..   . .        . |.  .       |. .|. . .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMR---EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KFPNISLPIHSQVLSLVISQLIKNKPYIDYFKDTDLKQFMKDKLANNIWMSKKYIYETCLQLVLGLKAIHNKNVLHLDIKPANLLLGLDLKWKYTDLGVS
|                                                 . |   . |.|   |   .| ||. | |.   | |.| ..  | .| | |
K------------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS

KNVDDE-------RDHTV----NLKG-ITACYSSPEQYQLYQFQSNKKITKQCDIYSLGVVFMEL-TGVDIRKKW-----VIKQKIRQKPFDKYLNPEFQ
....|.          ..    . |. .     .||  . . |      | . |..| ||.  |. |  .          .  | ....  . |  |  .
RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF------TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPP

E--------FNDAVLKNMM----QYNANQRIQLDELEVIL
.          |.. . .|    ......|    |.  ..
NDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase 13029.AA STE 76-132 19 4e-06 17.95 In-house 1-92 (359) Show / Hide 
Range on Protein: 76-132
Range on HMM: 1-92/359
Sequence Identity: 19% (18 aa)

FLDQTILGKGGNGYVLKGIDA----FNYK-------------VAIKVLKCETE-----------------EQYLQNQYEYENMKQCN--SKYV
. .. ..|||. | | |...     .. |             .|||... |..                 |.  | . | . ||.||  ....
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNI
Kinase 13029.AA Ciliate-E3 76-132 34 8e-06 14.49 In-house 1-64 (202) Show / Hide 
Range on Protein: 76-132
Range on HMM: 1-64/202
Sequence Identity: 34% (22 aa)

FLDQTILGKGGNGYVLKGIDA-FNYKVAIKVLKCETEEQ------YLQNQYEYENMKQCNSKYV
.. | |||.|. | | |. |   | .||||.. |. .            | |  | .| ||..|
YTVQQILGCGQFGRVYKAFDFQNNQDVAIKAIICQNQQNEGVGEQFQKTQQEFQNCQQINSQNV
Kinase 13029.AA Pkinase 76-132 25 0.002924 12.61 Pfam 1-62 (293) Show / Hide 
Range on Protein: 76-132
Range on HMM: 1-62/293
Sequence Identity: 25% (16 aa)

FLDQTILGKGGNGYVLKGIDAFNYK-VAIKVLKCETEEQYLQNQY-----EYENMKQCNSKYV
.    ..|.|. | | |...  . | ||.|..| . .|   ..|.     | . || .|....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNI
Kinase 13029.AA Ciliate-E1 82-138 22 0.009879 5.28 In-house 1-61 (202) Show / Hide 
Range on Protein: 82-138
Range on HMM: 1-61/202
Sequence Identity: 22% (14 aa)

LGKGGNGYVLKG-IDAFN-YKVAIKVLKCE---TEEQYLQNQYEYENMKQCNSKYVQIKYLI
.|.|. . |.|. ..  | ..||.|. .|.   ..........|| ....   |. .| ..|
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQII
Kinase 13029.AA Ciliate-B2 75-93 36 0.037193 0.75 In-house 1-18 (197) Show / Hide 
Range on Protein: 75-93
Range on HMM: 1-18/197
Sequence Identity: 36% (7 aa)

YFLDQTILGKGGNGYVLKG
|.| . ...||| | . .|
YYLCK-YINKGGCGFICEG
Kinase 13029.AA TKL 82-124 19 0.039266 3.49 In-house 1-77 (364) Show / Hide 
Range on Protein: 82-124
Range on HMM: 1-77/364
Sequence Identity: 19% (15 aa)

LGKGGNGYVLKGIDAF---------NYKVAIKVLKCET-------------------------EEQYLQNQYEYENM
.|.|| | | ||.            .. ||.|..| .                          | . .. . |.| |
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIM
Kinase 13029.AA ULK 76-132 21 0.067615 2.51 In-house 1-80 (329) Show / Hide 
Range on Protein: 76-132
Range on HMM: 1-80/329
Sequence Identity: 21% (17 aa)

FLDQTILGKGGNGYVLKGIDAFN-----YKVAIKVLK--CETEEQYLQN--------QYEYENMKQCN----SKY----V
.    .||||  |.| ||..  .      |||.|..    . .....|.        . | ..||. .    .|.    .
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNI
Kinase 13029.AA C8 76-113 28 0.14319 1.36 In-house 1-39 (226) Show / Hide 
Range on Protein: 76-113
Range on HMM: 1-39/226
Sequence Identity: 28% (11 aa)

FLDQTILGKGGNGYVLKGIDAF-NYKVAIKVLKCETEEQ
| .  .| .|. | |||.  .  | ....|..||. ...
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQD